Journal of Bioscience and Applied Research最新文献_第2页

Determination of ex vivo chemical and in vivo biological antioxidant activities of clary sage essential oil 测定香紫苏精油的体内外化学和生物抗氧化活性

Journal of Bioscience and Applied Research Pub Date : 2024-02-21 DOI: 10.21608/jbaar.2024.259473.1030

Saba M. J. Falih, Ali Al-Ali

引用次数: 0

Investigate the impact of probiotics of lactic acid bacteria obtained from various local sources on some pathogenic bacteria 研究从不同地方获取的乳酸菌益生菌对一些病原菌的影响

Journal of Bioscience and Applied Research Pub Date : 2024-02-11 DOI: 10.21608/jbaar.2024.256487.1029

Hasanain Mezaal

引用次数: 0

Physiological responses (HSH70, Mt), Oxidative stress, toxicity impacts, and risk assessment of the biomarker (Enochrus tenuicosta) to heavy metals contamination along the Red Sea coasts- Egypt. 埃及红海沿岸生物标志物（Enochrus tenuicosta）对重金属污染的生理反应（HSH70、Mt）、氧化应激、毒性影响和风险评估。

Journal of Bioscience and Applied Research Pub Date : 2024-02-05 DOI: 10.21608/jbaar.2024.339934

Eman Hassan, Eman Radwan, Gaber Saad, Nessrin Kheirallah

引用次数: 0

Physiological responses (HSH70, Mt), Oxidative stress, toxicity impacts, and risk assessment of the biomarker (Enochrus tenuicosta) to heavy metals contamination along the Red Sea coasts- Egypt. 埃及红海沿岸生物标志物（Enochrus tenuicosta）对重金属污染的生理反应（HSH70、Mt）、氧化应激、毒性影响和风险评估。

Journal of Bioscience and Applied Research Pub Date : 2024-02-05 DOI: 10.21608/jbaar.2024.339934

Eman Hassan, Eman Radwan, Gaber Saad, Nessrin Kheirallah

引用次数: 0

The combinatorial treatment with Kaempferol and β-sitosterol attenuates the hematological and lipid profile alterations induced by cisplatin in rats. 山奈酚和β-谷甾醇的组合疗法可减轻顺铂诱导的大鼠血液和血脂变化。

Journal of Bioscience and Applied Research Pub Date : 2024-01-09 DOI: 10.21608/jbaar.2024.334650

Islam Elebshany, Hala Abdel-Azeem, Zainab Attia, Mohamed Shahen

{"title":"The combinatorial treatment with Kaempferol and β-sitosterol attenuates the hematological and lipid profile alterations induced by cisplatin in rats.","authors":"Islam Elebshany, Hala Abdel-Azeem, Zainab Attia, Mohamed Shahen","doi":"10.21608/jbaar.2024.334650","DOIUrl":"https://doi.org/10.21608/jbaar.2024.334650","url":null,"abstract":"Chemotherapeutic agents are in use for cancer, however, these agents showed severe side effects on vital organs upon treatment. This study aimed to evaluate the protective effect of the combinatorial treatment with Kaempferol (Kpf) and β-sitosterol (Bs) in hematological parameters and lipid profile alterations induced by cisplatin (Cis) toxicity in rats. Sixty male Sprague-Dawley rats were divided into five groups (N = 12). The first group (Gp1) served as a negative control. From Gp2 to Gp5, rats were fed on a high-fat diet (HFD) for 4 weeks, then Gp2 was injected with a single dose of Cis (7mg/kg B.Wt). Gp3, Gp4, and Gp5 were injected with Cis as in Gp2, then administered with Kpf (50mg/Kg B.Wt), Bs (50mg/Kg B.Wt) or Kpf /Bs as in Gp3, Gp4, and Gp5, respectively. Blood samples were collected in heparinized and non-heparinized tubes for hematological and lipid profile investigations. The results showed that Cis treatment led to a significant decrease in the cellular compartments of blood and increased the mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC). Cis treatment also caused an increase in the total cholesterol (TC), triglycerides (TG), low-density lipoprotein (LDL-C), atherogenic index (Risk 1), lipoprotein (a), and decrease the high-density lipoprotein (HDL-C). The treatment with a combination of Kpf/Bs after Cis ameliorated the above-mentioned hematological and lipid profile alterations.","PeriodicalId":15163,"journal":{"name":"Journal of Bioscience and Applied Research","volume":"55 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139534957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MiRNA-122 association with TNF-α in some liver diseases of Egyptian patients 埃及肝病患者体内 MiRNA-122 与 TNF-α 的关系

Journal of Bioscience and Applied Research Pub Date : 2023-12-10 DOI: 10.21608/jbaar.2023.329927

A. Yameny, S. Alabd, Magda Mansor

{"title":"MiRNA-122 association with TNF-α in some liver diseases of Egyptian patients","authors":"A. Yameny, S. Alabd, Magda Mansor","doi":"10.21608/jbaar.2023.329927","DOIUrl":"https://doi.org/10.21608/jbaar.2023.329927","url":null,"abstract":": Background: Due to the high frequency of HCC, ongoing research is needed to find precise, non-invasive biomarkers for early identification and follow-up that will improve prognostic results. Patients and methods: this study was conducted on 90 patients with liver diseases and 25 healthy control G1, patients divided into 4 groups, (G2) 25 patients with HCV infection, (G3) 25 HCC+HCV infection, (G4) 25 patients with HBV infection, (G5) 15 patients with HCC + HBV. Results: Serum miR-122 and TNF-α levels were increased in HCV and HBV infection significantly with p-value >0.001 * compared to the control group, and their levels decreased when developed into HCC but still higher than the healthy subjects significantly with p-value >0.001. For discriminating HCV from HCV+HCC the cut-off for miR-122 was >7.1 at sensitivity 100%, specificity 100%, and the AUC was 1.0 (Excellent) P-value <0.001, also the sensitivity and specificity for TNF-α 72%, and 60% respectively with cut off >12.1 and AUC of 0.745 (Good) p-value 0.003. For discriminating HBV from HBV+HCC the cut-off for miR-122 was ≤6.4 at a sensitivity of 86.67% and specificity of 96%, and the AUC of miR-122 was 0.99 (Excellent) P-value <0.001, also the sensitivity and specificity for TNF-α 93.33%, and 48.0% respectively with cut-off ≤15.73, TNF-α has AUC of 0.527 (fair) it was not significant p-value 0.780.","PeriodicalId":15163,"journal":{"name":"Journal of Bioscience and Applied Research","volume":"9 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138982043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

International and national data on maternal, neonatal, and child mortality rates and policies to reduce the high in the Middle East and Morocco: a multilevel meta-analysis. 关于中东和摩洛哥孕产妇、新生儿和儿童死亡率的国际和国家数据以及降低高死亡率的政策：多层次荟萃分析。

Journal of Bioscience and Applied Research Pub Date : 2023-12-01 DOI: 10.21608/jbaar.2023.330290

A. Al-Selwi, Amina Barkat

引用次数: 0

Circulating MicroRNA-34a as a Promising Marker for Early Detection of Heart Failure Diseases in Egyptian Patients 循环 MicroRNA-34a 是埃及患者早期检测心衰疾病的有效标记物

Journal of Bioscience and Applied Research Pub Date : 2023-12-01 DOI: 10.21608/jbaar.2023.331876

Mohamed Nasr, Ahmed Hassanain, Wael El-Hakeem, Hamdi Abo Alazm, Randa Ghanoum, Sabah El Abed, Mohamed Ebaid

引用次数: 0

Whole Genome Sequence and Comparative Genomics Analysis of Citrobacter Freundii Isolate from burn skin 烧伤皮肤中弗赖登氏柠檬杆菌的全基因组序列和比较基因组学分析

Journal of Bioscience and Applied Research Pub Date : 2023-12-01 DOI: 10.21608/jbaar.2023.243629.1020

Namariq Al'Saadi, Ohood Radhi, Ali Hashim, Alaa Alabbas

引用次数: 0

Mothers’ Perception toward their Children who Suffering from Cerebral Palsy at the Pediatric Outpatient in Minia University Hospital 母亲对米尼亚大学医院儿科门诊脑瘫患儿的看法

Journal of Bioscience and Applied Research Pub Date : 2023-12-01 DOI: 10.21608/jbaar.2023.330453

Hager Hussein, Sahar El Awady, Aliaa El – afandy

{"title":"Mothers’ Perception toward their Children who Suffering from Cerebral Palsy at the Pediatric Outpatient in Minia University Hospital","authors":"Hager Hussein, Sahar El Awady, Aliaa El – afandy","doi":"10.21608/jbaar.2023.330453","DOIUrl":"https://doi.org/10.21608/jbaar.2023.330453","url":null,"abstract":"Background: Cerebral Palsy (CP ( is weakness or problems with using muscles and is caused by abnormal brain development or damage in the brain that affects a child's ability to control muscles. Aim : This study aimed to assess mothers’ perceptions toward children who suffer from CP. Research design: A descriptive design was used. Sample: Convenient sample included 200 mothers who have children with CP. Setting : Pediatric outpatient clinic in Minia University Hospital. Tool of data collection: One tool an interview questionnaire that includes 5 parts, 1 st part is demographic characteristics, 2 nd part is the past medical history of mothers and children, 3 rd part the mothers' knowledge, 4 th part: mothers’ reported practice, 5 th part: Mothers’ attitude scale. Results: 50% of studied mothers had poor knowledge. 30% had average knowledge and 20% had good knowledge about CP. 88% had unsatisfactory reported practice and 12% had satisfactory reported practice. 67 % had a negative attitude, and 33 % had a positive attitude. Conclusion: Most mothers had poor total knowledge about CP, most had unsatisfactory total reported practices, and more than two-thirds had negative attitudes about CP. There is a statistically significant relation between mothers’ sociodemographic data, knowledge, reported practices, and attitudes. Recommendations: Provide an education program for mothers and design booklets","PeriodicalId":15163,"journal":{"name":"Journal of Bioscience and Applied Research","volume":" 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139196204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0