Journal of Innovations in Applied Pharmaceutical Science (JIAPS)最新文献_第7页

Case report on ischemic stroke 缺血性脑卒中1例报告

Journal of Innovations in Applied Pharmaceutical Science (JIAPS) Pub Date : 2021-11-15 DOI: 10.37022/jiaps.v6i3.253

Chandini Kosuru, Sharmila T, Usha Sri Kanumula, T. Ch, Madhurismith V

引用次数: 0

Technical Documentation Requirements for Medical Devices Approval in European Union and a Detailed Emphasis on Air-way Products 欧盟医疗器械批准的技术文件要求和对气道产品的详细强调

Journal of Innovations in Applied Pharmaceutical Science (JIAPS) Pub Date : 2021-10-18 DOI: 10.37022/jiaps.v6i3.244

Shanmukhi Kondrath, Ramaiah Maddi

引用次数: 1

A review on vaccines – benefits and risks 疫苗的益处和风险综述

Journal of Innovations in Applied Pharmaceutical Science (JIAPS) Pub Date : 2021-09-30 DOI: 10.37022/JIAPS.V6I3.239

P. AkhilSusmith, Soha Sanobar, Prathyusha Vadluri, B. Sri, Pratap Kabya

引用次数: 0

Formulation and Evaluation of Ficus Benghalensis Emulgel for its Anti- Rheumatoid Arthritis Effect 榕树乳剂抗类风湿关节炎作用的配方及评价

Journal of Innovations in Applied Pharmaceutical Science (JIAPS) Pub Date : 2021-09-21 DOI: 10.37022/JIAPS.V6I3.230

Sonali, Mohd. Aqil Siddiqui, Amresh Gupta, Arpita Singh, Nitish Kumar

{"title":"Formulation and Evaluation of Ficus Benghalensis Emulgel for its Anti- Rheumatoid Arthritis Effect","authors":"Sonali, Mohd. Aqil Siddiqui, Amresh Gupta, Arpita Singh, Nitish Kumar","doi":"10.37022/JIAPS.V6I3.230","DOIUrl":"https://doi.org/10.37022/JIAPS.V6I3.230","url":null,"abstract":"The current study focuses on the development and characterization of ficus benghalensis powdered aerial roots emulgel to avoid the first-pass effect and strengthen bioavailability while reducing dosage intervals and dose-related deleterious reactions. three formulations with the same concentration and different polymers were formulated. Ethanolic and petroleum ether extract of dried aerial roots of ficus benghalensis were prepared by using different gelling agents like Carbopol 934, Carbopol 940, and Xanthane gum was formulated. The prepared formulations were evaluated for their qualitative as well as quantitative tests, physical appearance, pH, viscosity, spreadability, consistency, homogeneity, moisture loss, and finally in vitro anti-arthritic activity. Depending on the outcomes, it was observed that to all the formulation, F1 formulation containing Carbopol 940 with 4.6% moisture loss, 3780.3±5.0 viscosity and 6.1±0.1 PH and 43.7±1.53 spreadability shows better activity then all the other. Herbal emulgel of ethanolic extract of dried aerial roots of ficus benghalensis line, when compared with diclofenac emulgel, confirms the anti-arthritic activity through invitro release method.","PeriodicalId":151037,"journal":{"name":"Journal of Innovations in Applied Pharmaceutical Science (JIAPS)","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117002952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A review study on the anti depressant and anti oxidant activities of pisidum guajava and allium sativum 瓜石榴和葱属植物抗抑郁和抗氧化活性的研究进展

Journal of Innovations in Applied Pharmaceutical Science (JIAPS) Pub Date : 2021-09-20 DOI: 10.37022/JIAPS.V6I3.237

Anil Kumar Y, Lalitha Lavanya S. K, R. Konda, Prathyusha A

引用次数: 1

Formulation and optimization of synthetic polymer based herbal emulgel for anti-microbial activity 合成高分子植物抗微生物乳剂的配方及优化

Journal of Innovations in Applied Pharmaceutical Science (JIAPS) Pub Date : 2021-09-19 DOI: 10.37022/JIAPS.V6I3.217

N. Patel

{"title":"Formulation and optimization of synthetic polymer based herbal emulgel for anti-microbial activity","authors":"N. Patel","doi":"10.37022/JIAPS.V6I3.217","DOIUrl":"https://doi.org/10.37022/JIAPS.V6I3.217","url":null,"abstract":"The aim of the present research was to develop and evaluate the anti-microbial emulgel by using three different types of synthetic polymers. The active moiety selected for the formulation was the seeds of Carica papaya fruit. The formulation was developed by performing the extraction process; Soxhlet extraction with ethanol and water. The seeds of Carica papaya are reported to have anti-microbial properties. The skin-friendly i.e., the topical formulation was selected for development. Emulgel was prepared by incorporating different polymers and then evaluating each of them for best results. Basic evaluation parameters such as organoleptic parameters, viscosity, consistency, pH, homogeneity have been done, which demonstrate the results as per the reference and standard articles. Along with that, qualitative and quantitative tests of Carica seeds have also been performed, which indicates that the selected plant material is safe for usage. Finally, the most imp test, the anti-microbial test has been performed for determining the efficacy of prepared emulgel. Hence, it can be concluded that the prepared emulgel is safe and best for topical use as an anti-microbial. ","PeriodicalId":151037,"journal":{"name":"Journal of Innovations in Applied Pharmaceutical Science (JIAPS)","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126539925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Synthesis, characterization and anti-bacterial activity of novel schiff bases of pyridin-3 yl-carbohydrazide derivatives 新型希夫碱吡啶-3基碳酰肼衍生物的合成、表征及抗菌活性研究

Journal of Innovations in Applied Pharmaceutical Science (JIAPS) Pub Date : 2021-08-31 DOI: 10.37022/jiaps.v6i2.234

R. Konda, K. AnishKumar, M. PhaniLakshman, M. Asif, D. AnushaReddy

{"title":"Synthesis, characterization and anti-bacterial activity of novel schiff bases of pyridin-3 yl-carbohydrazide derivatives","authors":"R. Konda, K. AnishKumar, M. PhaniLakshman, M. Asif, D. AnushaReddy","doi":"10.37022/jiaps.v6i2.234","DOIUrl":"https://doi.org/10.37022/jiaps.v6i2.234","url":null,"abstract":"Heterocyclic compounds are cyclic compounds containing carbon and other heteroatoms. The most common heteroatoms are oxygen, nitrogen, and Sulphur. A heterocyclic compound is a cyclic compound that has atoms at least two different elements as members of its ring. A Schiff base (azomethine) is named after its inventor, Hugo Schiff and it is a functional group that contains a carbon-nitrogen double bond with the nitrogen atom connected to an aryl or alkyl group but not hydrogen. Schiff bases of Pyridin-3 yl-carbohydrazide derivatives from ethyl nicotinate and different aromatic aldehydes. Schiff’s bases are aromatic substituted imine compounds. These compounds are very important in the medicinal and pharmaceutical fields because of their wide spectrum of biological activity. Schiff’s bases show antibacterial activity, antifungal activity, and also antitumor activity. Aromatic aldehydes were refluxed with ethyl nicotinate using ethanol as a solvent to form Schiff's bases. All chemicals are taken in equimolar concentrations. The synthesized compounds were characterized by melting point, solubility, percentage yield, TLC, and IR spectral analysis. All derivatives are evaluated for anti-bacterial activity by the cup plate method. The antibacterial activity of test compounds was compared against standard Streptomycin. The 5 synthesized compounds show moderate antimicrobial activity. The experimental work summarizes the synthesis and in-vitro antibacterial activity of Schiff base derivatives.","PeriodicalId":151037,"journal":{"name":"Journal of Innovations in Applied Pharmaceutical Science (JIAPS)","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115171668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A review on vaccine pharmacovigilance during covid-19 covid-19期间疫苗药物警戒研究进展

Journal of Innovations in Applied Pharmaceutical Science (JIAPS) Pub Date : 1900-01-01 DOI: 10.37022/jiaps.v6i2.226

Jyothi K Navya, Archana Jaka, Velpula Padma sujaya Velpula Padma sujaya, Pallavi Nayak Rupavath, R. R. C. Vaddadi

{"title":"A review on vaccine pharmacovigilance during covid-19","authors":"Jyothi K Navya, Archana Jaka, Velpula Padma sujaya Velpula Padma sujaya, Pallavi Nayak Rupavath, R. R. C. Vaddadi","doi":"10.37022/jiaps.v6i2.226","DOIUrl":"https://doi.org/10.37022/jiaps.v6i2.226","url":null,"abstract":"Pharmacovigilance is important for collecting, detecting, monitoring adverse events which is the main objective. The adverse events reported should be assessed in order to know the casual relationship and avoid unnecessary effects on the recipient. Many people are vaccinating in a short period, so it is becoming much burden to the pharmacovigilance centers. The international society of pharmacovigilance (ISOP), the French national agency for medicines and health products safety (ANSM), and many others were in continuous collaboration and taking many initiatives to identify the safety and efficacy of vaccines and to provide answers to the raised questions respectively. Through pharmacovigilance, signals were detected, and many adverse events were identified. Pharmacovigilance of BioNTech/Pfizer-m-RNA, Moderna-mRNA vaccine, Covishield, Johnson and Johnson, Vaxzevria, Sputnik V, Convidecia are addressed. With BioNTech/Pfizer-m-RNA 12,249 ADRs, with Moderna-mRNA vaccine 577 ADRs, with Covishield 447 ADRs, with Johnson and Johnson 653 ADRs, with Vaxzevria 743 ADRs were reported. These vaccines resulted in immune thrombocytopenic purpura, cerebrovascular events, thrombosis, thrombocytopenia, facial paralysis, deaths, and many other reactions which may be fatal. But the events reported were less compared to the safety of the patients. All these events were maintained by the Uppsala monitoring center.","PeriodicalId":151037,"journal":{"name":"Journal of Innovations in Applied Pharmaceutical Science (JIAPS)","volume":"2015 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127325243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2