Yang Guan, Yao Sun, Xiaoyan Gao, Tian Tian, Jiaying Yang, Yi Xu
{"title":"Preparation and Functional Analysis of a New Cosmetics Raw Materials with Sika Deer Skin Peptide and Angelica Dahurica","authors":"Yang Guan, Yao Sun, Xiaoyan Gao, Tian Tian, Jiaying Yang, Yi Xu","doi":"10.12691/bb-8-1-1","DOIUrl":"https://doi.org/10.12691/bb-8-1-1","url":null,"abstract":"","PeriodicalId":15089,"journal":{"name":"Journal of Biomedicine and Biotechnology","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74017228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sabitha Vadakedath, V. Kandi, Vikram Godishala, Venkata Bharat Kumar Pinnelli, Samar Sami Alkafaas, Sara Sami EIkafas
{"title":"The Principle, Types, and Applications of Mass Spectrometry: A Comprehensive Review","authors":"Sabitha Vadakedath, V. Kandi, Vikram Godishala, Venkata Bharat Kumar Pinnelli, Samar Sami Alkafaas, Sara Sami EIkafas","doi":"10.12691/bb-7-1-2","DOIUrl":"https://doi.org/10.12691/bb-7-1-2","url":null,"abstract":"","PeriodicalId":15089,"journal":{"name":"Journal of Biomedicine and Biotechnology","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80404985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Toward Personalized Cell Therapies by Using Stem Cells 2012","authors":"K. Isobe, H. Cheung, Ji Wu","doi":"10.1155/2012/682192","DOIUrl":"https://doi.org/10.1155/2012/682192","url":null,"abstract":"1 Department of Immunology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan 2 Biomedical Engineering Department, College of Engineering, University of Miami, Coral Gables, FL, USA 3 Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai 200240, China 4 School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China","PeriodicalId":15089,"journal":{"name":"Journal of Biomedicine and Biotechnology","volume":"2012 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2012-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2012/682192","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64343680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erratum to “Unsupervised Two-Way Clustering of Metagenomic Sequences”","authors":"Shruthi Prabhakara, R. Acharya","doi":"10.1155/2012/795820","DOIUrl":"https://doi.org/10.1155/2012/795820","url":null,"abstract":"The reference in the originally published paper reads, “S. Nasser, A. Breland, F. Harris, and M. Nicolescu, “Metagenome fragment classification using n-mer frequency profiles,” in Proceedings of the Annual Meeting of the North American Fuzzy Information Processing Society (NAFIPS ‘08)*, pp. 1–6, New York, NY, USA, 2008.” \u0000 \u0000However, the correct reference for the citation is “Gail Rosen, Elaine Garbarine, Diamantino Caseiro, Robi Polikar, and Bahrad Sokhansanj, “Metagenome fragment classification using N-mer frequency profiles,” Advances in Bioinformatics, Volume 2008 (2008).”","PeriodicalId":15089,"journal":{"name":"Journal of Biomedicine and Biotechnology","volume":"2012 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2012-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2012/795820","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64353749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Genomic Instability, Inflammation, and Cancer","authors":"V. Gorgoulis","doi":"10.1155/2012/308043","DOIUrl":"https://doi.org/10.1155/2012/308043","url":null,"abstract":"Accumulating evidence supports that the inflammatory milieu plays a key role in the initiation and progression of epithelial cancer, the most characteristic example being that of ulcerative colitis which is associated with increased risk of colonic adenocarcinoma. Other less frequent and studied inflammatory lesions include asbestos-induced cellular damages, oral lichen planus (premalignant lesion), and cardiac myxoma. The mechanistic basis of this association is just beginning to be clarified. In the center of this picture lies the cytokine network which seems to link genomic instability, an evolving hallmark of cancer, with cancer development. In this special issue which deals with genomic instability, inflammation, and cancer, several research groups present evidence supporting this connection. \u0000 \u0000H. Matsuzaki et al. have demonstrated a relationship between chronic inflammation and carcinogenesis through asbestos-induced cellular and molecular alteration of immunocompetent cells, resulting in a decline in tumor immunity. Induction of chronic inflammation in the areas of the lung, regional lymph nodes and the pleural cavity has been shown to be due to the production of reactive oxygen/nitrogen species. Cellular and molecular features of immunocompetent cells may be altered by asbestos fibers which, combined with the surrounding inflammation, eventually lead to decreased tumor immunity. \u0000 \u0000M. Murata et al, have investigated the role of nitrative and oxidative DNA damage in inflammation-related carcinogenesis. In their work they revealed that infectious and noninfectious agents induce iNOS-dependent formation of 8-nitroguanine and 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) in cancer tissues and precancerous regions. Their results suggest that DNA base damage may lead to double-stranded breaks. They also demonstrated IL-6-modulated iNOS expression via STAT3 and EGFR in Epstein-Barr virus-associated nasopharyngeal carcinoma and found promoter hypermethylation in several tumor suppressor genes, while proposing 8-nitroguanine as potentially useful biomarkers for predicting the risk of inflammation-related cancers. \u0000 \u0000I. S. Pateras et al. have investigated the presence of herpes simplex virus (HSV) DNA in a cohort of cardiac myxomas assessing the possibility that HSV infection might be involved in the development of these lesions with potential therapeutic applications. \u0000 \u0000E. Georgakopoulou et al. have examined whether oral lichen planus exhibits malignant potential, with relation to the development of oral squamous cell carcinoma, and may therefore represent a model of preneoplastic inflammation. \u0000 \u0000I. Aivaliotis et al. have reviewed the effects of cytokines as crucial components of inflammation, participating in the interaction between the cells of the tumor microenvironment, and have focused on their potential role in the development of genomic instability. \u0000 \u0000This special issue of the Journal of Biomedicine and Biotechnology is devoted to the p","PeriodicalId":15089,"journal":{"name":"Journal of Biomedicine and Biotechnology","volume":"2012 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2012-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2012/308043","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64311871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Ballesteros-Rodea, M. Santillán, S. Martínez-Calvillo, R. Manning-Cela
{"title":"Erratum to “Flagellar Motility of Trypanosoma cruzi Epimastigotes”","authors":"G. Ballesteros-Rodea, M. Santillán, S. Martínez-Calvillo, R. Manning-Cela","doi":"10.1155/2012/793487","DOIUrl":"https://doi.org/10.1155/2012/793487","url":null,"abstract":"The authors would like to make the following changes. \u0000 \u0000(1) In the Results Section 3.3. Vectorial Analysis of Parasites Trajectories, third paragraph, the sentence: this behavior was clearly observed when speed and rotational angle were analyzed together (Figure 7) should be replaced by the following sentence: this behavior was clearly observed in the parasite trajectories, like the one pictured in Figure 7. \u0000 \u0000 \u0000 \u0000Figure 7 \u0000 \u0000 \u0000 \u0000(2) The legend of Figure 7, Figure 7: Analysis of parasite trajectory. The trajectory of free-swimming epimastigotes was determined using the speed and rotational angle results form a 10-second recording. The histogram is representative of the average behavior of 20 randomly selected epimastigotes, should be replaced by Figure 7: Analysis of a single parasite trajectory. The trajectory of a typical free-swimming epimastigote was recorded for 10 seconds. \u0000 \u0000(3) Figure 7 that is in the original paper should be replaced by the following figure.","PeriodicalId":15089,"journal":{"name":"Journal of Biomedicine and Biotechnology","volume":"2012 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2012-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2012/793487","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64353003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bionanotechnology and Nanomedicine","authors":"P. Chase, Seunghun Hong, A. Månsson, P. Xiong","doi":"10.1155/2012/763967","DOIUrl":"https://doi.org/10.1155/2012/763967","url":null,"abstract":"This special issue contains contributions from the broad interdisciplinary fields of bionanotechnology and nanomedicine. Nanotechnology has great promise in biology and medicine. This includes new approaches to fundamental studies, improved methods for detection of protein or nucleic acid-based biomarkers of disease, and new ways to administer drugs or vaccines or enhancing their effects. The tools of nanotechnology provide new insights into mechanisms of normal biological functions and diseases. Novel nanotechnology-based imaging methods reveal structural and functional information at progressively higher levels of resolution, both in vitro, in cells and in organisms. Molecular components of biological systems on their own can be often viewed as nanoscale machines with functions that have been tuned through evolution and with design principles often based on self-assembly and self-organization phenomena. These biological nanomachines can be incorporated into micro- and nanofabricated devices, a merger that yields novel structures and functionalities.","PeriodicalId":15089,"journal":{"name":"Journal of Biomedicine and Biotechnology","volume":"2012 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2012-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2012/763967","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64351505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recent advances in imaging of dopaminergic neurons for evaluation of neuropsychiatric disorders.","authors":"Lie-Hang Shen, Mei-Hsiu Liao, Yu-Chin Tseng","doi":"10.1155/2012/259349","DOIUrl":"https://doi.org/10.1155/2012/259349","url":null,"abstract":"<p><p>Dopamine is the most intensely studied monoaminergic neurotransmitter. Dopaminergic neurotransmission plays an important role in regulating several aspects of basic brain function, including motor, behavior, motivation, and working memory. To date, there are numerous positron emission tomography (PET) and single photon emission computed tomography (SPECT) radiotracers available for targeting different steps in the process of dopaminergic neurotransmission, which permits us to quantify dopaminergic activity in the living human brain. Degeneration of the nigrostriatal dopamine system causes Parkinson's disease (PD) and related Parkinsonism. Dopamine is the neurotransmitter that has been classically associated with the reinforcing effects of drug abuse. Abnormalities within the dopamine system in the brain are involved in the pathophysiology of attention deficit hyperactivity disorder (ADHD). Dopamine receptors play an important role in schizophrenia and the effect of neuroleptics is through blockage of dopamine D(2) receptors. This review will concentrate on the radiotracers that have been developed for imaging dopaminergic neurons, describe the clinical aspects in the assessment of neuropsychiatric disorders, and suggest future directions in the diagnosis and management of such disorders.</p>","PeriodicalId":15089,"journal":{"name":"Journal of Biomedicine and Biotechnology","volume":"2012 ","pages":"259349"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2012/259349","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9375073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Philippe Jeandet, Bertrand Delaunois, Aziz Aziz, David Donnez, Yann Vasserot, Sylvain Cordelier, Eric Courot
{"title":"Metabolic engineering of yeast and plants for the production of the biologically active hydroxystilbene, resveratrol.","authors":"Philippe Jeandet, Bertrand Delaunois, Aziz Aziz, David Donnez, Yann Vasserot, Sylvain Cordelier, Eric Courot","doi":"10.1155/2012/579089","DOIUrl":"https://doi.org/10.1155/2012/579089","url":null,"abstract":"<p><p>Resveratrol, a stilbenic compound deriving from the phenyalanine/polymalonate route, being stilbene synthase the last and key enzyme of this pathway, recently has become the focus of a number of studies in medicine and plant physiology. Increased demand for this molecule for nutraceutical, cosmetic and possibly pharmaceutic uses, makes its production a necessity. In this context, the use of biotechnology through recombinant microorganisms and plants is particularly promising. Interesting results can indeed arise from the potential of genetically modified microorganisms as an alternative mechanism for producing resveratrol. Strategies used to tailoring yeast as they do not possess the genes that encode for the resveratrol pathway, will be described. On the other hand, most interest has centered in recent years, on STS gene transfer experiments from various origins to the genome of numerous plants. This work also presents a comprehensive review on plant molecular engineering with the STS gene, resulting in disease resistance against microorganisms and the enhancement of the antioxidant activities of several fruits in transgenic lines.</p>","PeriodicalId":15089,"journal":{"name":"Journal of Biomedicine and Biotechnology","volume":"2012 ","pages":"579089"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2012/579089","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9380444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bum Ju Lee, Boncho Ku, Kihyun Park, Keun Ho Kim, Jong Yeol Kim
{"title":"A new method of diagnosing constitutional types based on vocal and facial features for personalized medicine.","authors":"Bum Ju Lee, Boncho Ku, Kihyun Park, Keun Ho Kim, Jong Yeol Kim","doi":"10.1155/2012/818607","DOIUrl":"10.1155/2012/818607","url":null,"abstract":"<p><p>The aim of the present study is to develop an accurate constitution diagnostic method based solely on the individual's physical characteristics, irrespective of psychologic traits, characteristics of clinical medicine, and genetic factors. In this paper, we suggest a novel method for diagnosing constitutional types using only speech and face characteristics. Based on 514 subjects, the area under the receiver operating characteristics curve (AUC) values of classification models in age and gender groups ranged from 0.64 to 0.89. We identified significant features showing statistical differences among three constitutional types by performing statistical analysis. Also, we selected a compact and discriminative feature subset for constitution diagnosis in each age and gender group. Our method may support the direction of improved diagnosis prediction and will serve to develop a personal and automatic constitution diagnosis software for improvement of the effectiveness of prescribed medications and development of personalized medicine.</p>","PeriodicalId":15089,"journal":{"name":"Journal of Biomedicine and Biotechnology","volume":"2012 ","pages":"818607"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415144/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10269733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}