Journal of Biochemical Technology最新文献

Effectiveness of the Use of Citrulline Malate to Increase the Powerlifters Adaptive Potential and Physical Performance 使用瓜氨酸苹果酸提高举重运动员适应潜能和体能的有效性

IF 0.5

Journal of Biochemical Technology Pub Date : 2023-01-01 DOI: 10.51847/gd16a1jnmz

A. Tishchenko, Diana Aleksandrovna Kaplanyan, Viktoriya Andreevna Krechetova, Yaramir Khadzhiretovich Frantsuzov, Islam Shamilovich Shakhbanov, Anita Varuzhanovna Chnavayan

引用次数: 0

Metformin Anti-Tumor Effect and Metabolic Reprogramming in Breast Cancer Cells 二甲双胍在乳腺癌细胞中的抗肿瘤作用和代谢重编程

IF 0.5

Journal of Biochemical Technology Pub Date : 2023-01-01 DOI: 10.51847/u62zz2npvj

Feryal Alharthy, A. Alamoudi, Amina Alnouri, Arwa Alkhuzaee, G. Ajabnoor, Mehal A AlQriqri, H. Gad, H. Choudhry, A. Aldahlawi, R. R. Basheer

引用次数: 0

The State Biology Museum Named after Kliment Arkadyevich Timiryazev as a Scientific and Educational Center 国家生物博物馆以Kliment Arkadyevich Timiryazev命名，作为科学和教育中心

IF 0.5

Journal of Biochemical Technology Pub Date : 2023-01-01 DOI: 10.51847/olkerwxo55

Michail A. Osadchuk, A. Osadchuk, Inna Vasilieva, M. Trushin

引用次数: 0

Treatment of Menstruation Disorders at Puberty: A Plant-Based Dietary Supplement Efficacy and Safety 青春期月经紊乱的治疗:植物性膳食补充剂的有效性和安全性

Journal of Biochemical Technology Pub Date : 2023-01-01 DOI: 10.51847/r9vjre0mhw

Valery Petrovich Sergun, Bereslavets Evgenia, Valentina Nikolaevna Burkova, Valeriy Mikhailovich Poznyakovsky, Nadezhda Nikolaevna Danko, Boisjoni Tokhiriyon

{"title":"Treatment of Menstruation Disorders at Puberty: A Plant-Based Dietary Supplement Efficacy and Safety","authors":"Valery Petrovich Sergun, Bereslavets Evgenia, Valentina Nikolaevna Burkova, Valeriy Mikhailovich Poznyakovsky, Nadezhda Nikolaevna Danko, Boisjoni Tokhiriyon","doi":"10.51847/r9vjre0mhw","DOIUrl":"https://doi.org/10.51847/r9vjre0mhw","url":null,"abstract":"Primary dysmenorrhea harms the physical and social functioning of many young women. At the Siberian State Medical University laboratory complex and Tomsk prenatal clinic No. 4 antenatal clinic, a clinical experiment was conducted to better understand the impact of diet on the treatment of menstrual problems. In the clinical experiment, sixty young women with dysmenorrhea between the ages of 14 and 18 took part. To assess the efficacy of complex treatment both objective and subjective performance criteria were used. All the participants underwent numerous examinations before the trial, and the whole process of the treatment was carefully recorded and analyzed. The supplement was prescribed to complement the conventional cyclic vitamin therapy. The tested dietary supplement demonstrated bacterial, anti-inflammatory, and immune-stimulating effects. The favorable impact of the supplement on the autonomic nervous system was registered. The participants of the experimental group experienced pain relief and demonstrated a noticeable improvement. No side effects were detected during the clinical trial.","PeriodicalId":15062,"journal":{"name":"Journal of Biochemical Technology","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135312504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Food Biochemistry in The Control and Prevention of Nervous System Diseases 食品生物化学在控制和预防神经系统疾病中的作用

Journal of Biochemical Technology Pub Date : 2023-01-01 DOI: 10.51847/atdejs15py

Florica Voiţă-Mekereş, Felicia Manole, Ioan Bogdan Voiţă, Paula Marian

引用次数: 0

Arterial Hypertension in Ukraine: Medical and Social Problems of Pathogenesis 乌克兰动脉高血压:发病机制的医学和社会问题

IF 0.5

Journal of Biochemical Technology Pub Date : 2023-01-01 DOI: 10.51847/uhbo9d7zip

N. Korylchuk, R. Riabushko, I. Haman, Anatolija Krasnova, N. Dovzhuk

{"title":"Arterial Hypertension in Ukraine: Medical and Social Problems of Pathogenesis","authors":"N. Korylchuk, R. Riabushko, I. Haman, Anatolija Krasnova, N. Dovzhuk","doi":"10.51847/uhbo9d7zip","DOIUrl":"https://doi.org/10.51847/uhbo9d7zip","url":null,"abstract":"Arterial hypertension is becoming increasingly common among diseases of the cardiovascular system. The work aimed to analyze blood pressure control in patients diagnosed with arterial hypertension. Fifty physicians and 1020 patients (under 56 years of age) participated in the study. Regular use of medications was observed in 92% of the patients, and the systolic blood pressure level was 167 mm Hg. More frequent use of renin-angiotensin system blockers compared with diuretics and calcium antagonists was noted, both in monotherapy and in combination therapy. Target BP was achieved in 66% of cases within three months by therapy with amlodipine and retarded indapamide. The majority of patients adhered to the prescribed therapy (97%). The effectiveness of amlodipine and indapamide therapy was in direct correlation with baseline BP values. Significant factors were smoking (lower efficacy), and gender (higher in women). The degree of BP reduction following combined therapy with amlodipine and indapamide was determined to be directly correlated with the beginning BP level. At the same time, female patients and non-smokers see more pronounced dynamics of BP lowering. Pre-treatment is also a crucial element; statins and renin system blockers greatly lower blood pressure when used together.","PeriodicalId":15062,"journal":{"name":"Journal of Biochemical Technology","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70835592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibiotics Coupled with Photothermal Therapy for the Enhanced Killing of Bacteria. 抗生素与光热疗法相结合，增强杀灭细菌的效果。

IF 0.5

Journal of Biochemical Technology Pub Date : 2023-01-01 Epub Date: 2023-09-26 DOI: 10.51847/nplvoycg9u

Amanda Jalihal, Armin Mortazi, Mavis Forson, Mujeebat Bashiru, Thuy Le, Adeniyi Oyebade, Noureen Siraj

{"title":"Antibiotics Coupled with Photothermal Therapy for the Enhanced Killing of Bacteria.","authors":"Amanda Jalihal, Armin Mortazi, Mavis Forson, Mujeebat Bashiru, Thuy Le, Adeniyi Oyebade, Noureen Siraj","doi":"10.51847/nplvoycg9u","DOIUrl":"10.51847/nplvoycg9u","url":null,"abstract":"In this study, the application of ionic materials as a combination antibiotic drug was investigated. The fluoroquinolone, Norfloxacin, was converted into the ionic form and combined with the cationic dye, IR780+, using an ion-exchange reaction. The resulting ionic combination drug possesses two killing mechanisms in one compound. The antibiotic chemical mechanism along with the photothermal mechanism that was acquired by adding IR780 to the compound led to the development of a combination antibiotic drug. This ionic combination drug consisting of Norfloxacin anion and IR780 cation is easily dispersed in water using sonication waves. The parent compounds and ionic combination drug, dissolved in organic solvent and dispersed in water, were characterized, and the photophysical properties were studied in detail. It was discovered that the aqueous ionic combination drugs exhibited significant changes in absorbance and photoluminescent properties. In aqueous media, the dispersed ionic combination drug exhibited a very broad absorbance with an additional peak around 1000 nm which is advantageous in photothermal. A significant decrease in the quantum yield along with enhanced non-radiative rate constant was observed for the combination drug in the aqueous. The photothermal mechanism is present in both the parent IR780 dye and the ionic combination drug. The ionic combination drug displayed a high light-to-heat conversion efficiency and temperature increase similar to the parent dye. The combination of both killing mechanisms in the ionic combination drug resulted in enhanced antibacterial activity against Escherichia coli as compared to the parent Norfloxacin and IR780-I individually.","PeriodicalId":15062,"journal":{"name":"Journal of Biochemical Technology","volume":"14 3","pages":"50-58"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10766427/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139097910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study of Blood-Ocular Barrier Permeability by Levomecitin Group Drugs in Normal and Pathological Conditions 左旋美西丁组药物对正常和病理血眼屏障通透性的影响

IF 0.5

Journal of Biochemical Technology Pub Date : 2023-01-01 DOI: 10.51847/dwoixyzfkz

Daria Andreevna Gorokhova, Karolina Karenovna Tsaturyan, Albert Armenovich Engibaryan, Valeriia Fedorovna Bosenko, N. V. Makarenko, Anna Vladimirovna Chernookova

{"title":"Study of Blood-Ocular Barrier Permeability by Levomecitin Group Drugs in Normal and Pathological Conditions","authors":"Daria Andreevna Gorokhova, Karolina Karenovna Tsaturyan, Albert Armenovich Engibaryan, Valeriia Fedorovna Bosenko, N. V. Makarenko, Anna Vladimirovna Chernookova","doi":"10.51847/dwoixyzfkz","DOIUrl":"https://doi.org/10.51847/dwoixyzfkz","url":null,"abstract":"An eye defense mechanism called the blood-ocular barrier stops hazardous compounds from the circulatory system from entering the eye's structural components. In order to preserve human health and quality of life, the blood-ocular barrier must operate at its peak. There are several eye illnesses that might be linked to a breach in the blood-ocular barrier's functionality. The blood-ocular barrier's permeability to medications in the levomecitin group was examined in this paper under both healthy and unhealthy circumstances. A total of 40 laboratory rabbits were divided into two groups for this reason, and the experimental group's rabbits underwent artificial induction of keratoconjunctivitis. In the posterior femoral muscle group of rabbits in the control and experimental groups, a 30 mg/kg dose of a 10% chloramphenicol solution diluted in a 0.5% novocaine solution was intramuscularly administered twice, separated by a 12-hour interval. Next, the behavior and health of the rabbits in both groups were observed, along with routine checks on the animals' body temperatures, pulses, and respirations. On several experiment days, the level of chloramphenicol in blood serum and intraocular fluid was examined in order to gauge the permeability of the blood-ocular barrier. Further research was done on the biochemical and hematological characteristics of blood serum.","PeriodicalId":15062,"journal":{"name":"Journal of Biochemical Technology","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70819139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Applications of Deep Learning and Machine Learning in Computational Medicine 深度学习和机器学习在计算医学中的应用

IF 0.5

Journal of Biochemical Technology Pub Date : 2023-01-01 DOI: 10.51847/iw1dfvoxvw

R. Adiga, Titas Biswas, P. Shyam

引用次数: 1

Plant Biotechnology Potential for Food Production: The Tyumen Region 植物生物技术在粮食生产中的潜力:秋明地区

Journal of Biochemical Technology Pub Date : 2023-01-01 DOI: 10.51847/hsrseyplwa

Marina Viktorovna Nikolenko, Vera Viktorovna Trigub, Vladimir Grigorievich Popov, Elena Viktorovna Ragozinnikova, Galina Georgievna Cherentsova, Boisjoni Tokhiriyon

引用次数: 0