Journal of Applied Animal Research最新文献_第8页

Proximate composition and mineral profile of elephants forages in the Savannah ecological zone of Ghana 加纳萨凡纳生态区大象觅食的近似成分和矿物特征

IF 1.4 4区农林科学

Journal of Applied Animal Research Pub Date : 2023-09-02 DOI: 10.1080/09712119.2023.2250409

Sylvenus Aguree, Samson Abah Abagale, Isaac Sackey

{"title":"Proximate composition and mineral profile of elephants forages in the Savannah ecological zone of Ghana","authors":"Sylvenus Aguree, Samson Abah Abagale, Isaac Sackey","doi":"10.1080/09712119.2023.2250409","DOIUrl":"https://doi.org/10.1080/09712119.2023.2250409","url":null,"abstract":"ABSTRACT\u0000 This study evaluated the proximate and mineral composition of various parts of Balanites aegyptiaca, Mitragyna inermis, Cassia sieberiena, Kigelia africana, Detarium microcarpum, Terminalia laxiflora, Ficus platyphylla and Climber plant (Liana) as feeds of elephants in the savannah ecological zone of Ghana. The proximate composition was carried out using the methods of the Association of official analytical chemists (AOAC) and the mineral profiles were determined by atomic absorption and flame photometric methods. The highest content of Crude Protein, Crude Fibre, Ash, Moisture and Nitrogen free extract were 12.0% ± 0.01, 15.3% ± 0.01, 14.6% ± 0.0, 7.5% ± 0.01, 76.6% ± 0.01 for Ficus platyphylla, Tamarindus indica, Balanites aegyptiaca and Detarium microcarpum, respectively. The mineral profiling also found appreciable levels of Ca, Mg, P, K, Na, Zn, Cu, Fe, Se and Mn at concentrations (mg/kg) of 4.6 ± 0.00, 0.4 ± 0.01, 0.4 ± 0.01, 5.1 ± 0.01, 0.11 ± 0.01, 1.07 ± 0.008, 0.25 ± 0.005, 0.063 ± 0.0005, 37.48 ± 0.001 for Ficus platyphylla bark, Liana, Terminalia laxiflora bark and leaves, Mitragyna inermis bark, Terminalia laxiflora leaves and Mitragyna inermis leaves, respectively. Presentation of the presence of these important nutrients would be a guide to zoo managers and wildlife practitioners on the best quality of feeds to select for wild elephants.","PeriodicalId":15030,"journal":{"name":"Journal of Applied Animal Research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2023-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46473550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Alternative organic wastes as substrates and its impact on growth, proximate chemical and mineral composition of black soldier fly (Hermetia illucens) larvae for subsistent animal feed 替代有机废物作为底物及其对黑兵蝇(Hermetia illucens)幼虫生长、近因化学和矿物组成的影响

IF 1.4 4区农林科学

Journal of Applied Animal Research Pub Date : 2023-08-22 DOI: 10.1080/09712119.2023.2249545

O. Opoku, J. Hamidu, B. Adjei-Mensah, B. Quaye, Prince Sasu, V. Benante, M. A. Amankrah, A. Donkoh, C. C. Atuahene

{"title":"Alternative organic wastes as substrates and its impact on growth, proximate chemical and mineral composition of black soldier fly (Hermetia illucens) larvae for subsistent animal feed","authors":"O. Opoku, J. Hamidu, B. Adjei-Mensah, B. Quaye, Prince Sasu, V. Benante, M. A. Amankrah, A. Donkoh, C. C. Atuahene","doi":"10.1080/09712119.2023.2249545","DOIUrl":"https://doi.org/10.1080/09712119.2023.2249545","url":null,"abstract":"ABSTRACT\u0000 This study explored the growth parameters and nutritional composition of Black soldier fly larvae (BSFL) reared on some selected alternative organic waste materials. The substrates comprised wheat bran (WB) as the control, millet waste (MW), restaurant leftovers (RL) and fruits waste (FW) and were replicated 8 times in a mini-insectary set-up. Proximate nutrient and mineral composition of the larvae were analyzed. RL had the highest (p < 0.0001) total weight of larvae, number of larvae, efficiency of conversion and substrate reduction index compared to the other substrates. Crude protein (%) content of the BSFL was superior (p < 0.000) in the WB and MW substrate groups at 41.1% and 41.4%, respectively. Crude protein and dry matter yield (g) of the BSFL was higher (p < 0.0001) in the RL than in the other substrates. Metabolizable energy and dry matter were superior (p < 0.0001) in MW and RL groups respectively to all the other substrate groups. RL recorded the lowest (p < 0.0001) phosphorus and calcium levels relative to the other substrates. Conclusively, the crude protein content of the BSFL irrespective of the substrates was adequate to be employed in the livestock feed industry.","PeriodicalId":15030,"journal":{"name":"Journal of Applied Animal Research","volume":"101 23","pages":""},"PeriodicalIF":1.4,"publicationDate":"2023-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41251125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of palm kernel cake on the growth performance, gut health and hematochemical indices of slow-growing broilers 棕榈仁饼对慢生长肉鸡生长性能、肠道健康和血液化学指标的影响

4区农林科学

Journal of Applied Animal Research Pub Date : 2023-08-02 DOI: 10.1080/09712119.2023.2242447

Achiamaa Asafu-Adjaye Koranteng, Koffi Apeti Gbogbo, Benjamin Adjei-Mensah, Tchilabalou Bouassi, Richard Koblah Agbehadzi, Kokou Tona

{"title":"Influence of palm kernel cake on the growth performance, gut health and hematochemical indices of slow-growing broilers","authors":"Achiamaa Asafu-Adjaye Koranteng, Koffi Apeti Gbogbo, Benjamin Adjei-Mensah, Tchilabalou Bouassi, Richard Koblah Agbehadzi, Kokou Tona","doi":"10.1080/09712119.2023.2242447","DOIUrl":"https://doi.org/10.1080/09712119.2023.2242447","url":null,"abstract":"Four hundred and fifty (450) 3-week-old male and female broiler chicks were randomly allocated to a control diet and four dietary treatments with six replicates in a completely randomized design (CRD) with 15 birds per replicate arranged in a 2 × 2 factorial design to evaluate the effect of palm kernel cake (PKC) diet and multi-blend enzymes on the performance of Sasso broilers. The five dietary treatments were T0 = (control, standard diet), T1 = PKC1*0% (10% PKC with no enzyme), T2 = PKC1*0.05% (10% PKC with enzyme), T3 = PKC2*0% (20% PKC with no enzyme) and T4 = PKC2*0.05% (20% PKC with enzyme). The interactive effect of PKC and enzyme showed improved (p < 0.05) FCR in T1 and T2. Higher counts (p < 0.05) of Lactobacillus spp. were found in PKC2 than in PKC1 and lower Clostridium perfringens counts in T3 compared to T2 at 8 weeks. At week 12, the PKC-enzyme effect resulted in higher (p < 0.05) platelets in the T2 and T4 groups than in the other treatments. The incorporation of 10% PKC with enzyme into the diets of Sasso broilers could maintain bacteria balance in their gut and enhance growth performance.","PeriodicalId":15030,"journal":{"name":"Journal of Applied Animal Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135015331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The relationship between vitamin A status and oxidative stress in animal production 动物生产中维生素A水平与氧化应激的关系

IF 1.4 4区农林科学

Journal of Applied Animal Research Pub Date : 2023-07-27 DOI: 10.1080/09712119.2023.2239319

Y. Shastak, Alvaro Gordillo, W. Pelletier

{"title":"The relationship between vitamin A status and oxidative stress in animal production","authors":"Y. Shastak, Alvaro Gordillo, W. Pelletier","doi":"10.1080/09712119.2023.2239319","DOIUrl":"https://doi.org/10.1080/09712119.2023.2239319","url":null,"abstract":"ABSTRACT\u0000 Oxidative stress is caused by an imbalance between the production of harmful oxygen molecules and the body's ability to repair their detrimental implications, leading to reduced growth rates, increased disease susceptibility, and decreased reproductive performance in animals. Vitamin A, comprising retinol, retinal, and retinoic acid, is crucial for normal growth, reproduction, and vision. Vitamin A possesses antioxidant properties by directly scavenging reactive oxygen species, boosting antioxidant enzyme activity, and promoting antioxidant defence mechanisms. Numerous studies have shown that livestock with adequate levels of vitamin A in their diet experience reduced oxidative stress compared to those with vitamin A deficiency. Moreover, vitamin A supplementation can mitigate oxidative stress in animals exposed to stressful conditions like heat stress. Adequate vitamin A status in livestock through dietary interventions and improved animal management practices can significantly benefit animal health and well-being. However, further research is still needed to optimize dosing strategies and fully understand the relationship between vitamin A and oxidative stress in different animal species and production systems. Therefore, continued research efforts are essential to fully harness the potential of vitamin A as an effective tool for mitigating oxidative stress and improving animal welfare.","PeriodicalId":15030,"journal":{"name":"Journal of Applied Animal Research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45850717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Genetic screening between Italian and Romanian water buffalo 意大利和罗马尼亚水牛的遗传筛选

IF 1.4 4区农林科学

Journal of Applied Animal Research Pub Date : 2023-07-25 DOI: 10.1080/09712119.2023.2237618

C. Rossetti, V. Genualdo, A. Perucatti, D. Incarnato, I. Nicolae

引用次数: 0

Detection and identification of foot-and-mouth disease O/ME-SA/Ind-2001 virus lineage, Indonesia, 2022 口蹄疫O/ME-SA/Ind-2001病毒谱系的检测和鉴定，印度尼西亚，2022

IF 1.4 4区农林科学

Journal of Applied Animal Research Pub Date : 2023-07-24 DOI: 10.1080/09712119.2023.2229414

Edy Budi Susila, Rosmalina Sari Dewi Daulay, Dewi Noor Hidayati, Sapto Rini Budi Prasetyowati, Wriningati, Ernes Andesfha, S. H. Irianingsih, I. Dibia, Faisal, A. Supriyadi, Y. Yupiana, M. Hidayat, N. Zainuddin, H. Wibawa

{"title":"Detection and identification of foot-and-mouth disease O/ME-SA/Ind-2001 virus lineage, Indonesia, 2022","authors":"Edy Budi Susila, Rosmalina Sari Dewi Daulay, Dewi Noor Hidayati, Sapto Rini Budi Prasetyowati, Wriningati, Ernes Andesfha, S. H. Irianingsih, I. Dibia, Faisal, A. Supriyadi, Y. Yupiana, M. Hidayat, N. Zainuddin, H. Wibawa","doi":"10.1080/09712119.2023.2229414","DOIUrl":"https://doi.org/10.1080/09712119.2023.2229414","url":null,"abstract":"ABSTRACT\u0000 Foot-and-mouth disease (FMD) is a contagious disease affecting cloven-hoofed animals, which has been well-documented as one of the major animal diseases that causes severe economic loss in livestock sectors. The disease is endemic in many countries, particularly in Asia and Africa. Indonesia has been declared a disease-free country since 1986, and the World Organization of Animal Health (WOAH/OIE) recognized Indonesia as an FMD-free country without vaccination in 1990. However, the FMD virus was detected in many disease outbreaks in cattle and goats in Indonesia in May 2022. This study reports the detection and identification of FMD serotype O viruses in Indonesia. Although these viruses appeared to belong to the ME-SA/Ind-2001e lineage, they formed a unique cluster with 95.3% average nucleotide sequence similarity of the FMD VP1 gene to Ind-2001e viruses from other Asia countries. The illegal trade of live animals from endemic areas in Southeast Asia is one of the possible routes regarding the incursion of FMD in Indonesia, however, it requires further investigation.","PeriodicalId":15030,"journal":{"name":"Journal of Applied Animal Research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2023-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48496515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Zootechnical performances and profitability of local breed’s pigs fattened through the application of feed and health technological packages in traditional livestock farms in Casamance, Senegal 在塞内加尔卡萨芒斯的传统牲畜养殖场中，通过饲料和卫生技术包的应用，饲养当地品种猪的动物技术性能和盈利能力

IF 1.4 4区农林科学

Journal of Applied Animal Research Pub Date : 2023-07-13 DOI: 10.1080/09712119.2023.2231243

W. Ossebi, S. B. Ayssiwede, S. Atchiwassa, A. E. Djettin, Richard Malou, M. Diop, A. Missohou

{"title":"Zootechnical performances and profitability of local breed’s pigs fattened through the application of feed and health technological packages in traditional livestock farms in Casamance, Senegal","authors":"W. Ossebi, S. B. Ayssiwede, S. Atchiwassa, A. E. Djettin, Richard Malou, M. Diop, A. Missohou","doi":"10.1080/09712119.2023.2231243","DOIUrl":"https://doi.org/10.1080/09712119.2023.2231243","url":null,"abstract":"ABSTRACT This work aims to assess the effects of the application of feed and health technological packages on the zootechnical-economic performance of local breeds pigs in Casamance. It involved 253 young pigs, provided by 44 traditional farms. The feed and health technological package group (FHT) pigs were kept in permanent confinement and fed ad-libitum with a diet containing 15% of dried cashew apple pulp, while the controls and health technological package (HT) pigs were raised in a free-range area and fed in the usual way by the farmers. The zootechnical and economic parameters were collected and processed by ANOVA test and linear regression. The results showed a significant improvement in health status, live body weight, carcass weight of pigs, daily weight gain mean of the pigs in the FHT group compared to the HT and controls (p < 0.05). The production costs of the FHT pigs were lower than those of the HT and control pigs’ groups. They generated on average a gain for the selling in live body weight and a loss for those in carcass weight. The use of feed and health technological packages is advised in pig farming and price incentives are necessary to make the fattening activity sustainable.","PeriodicalId":15030,"journal":{"name":"Journal of Applied Animal Research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42481244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutrient intake and blood profile of Nellore calves supplemented with cellulolytic fungi from rumen 添加瘤胃纤维素分解真菌对内洛雷小牛营养物质摄入量和血液特性的影响

IF 1.4 4区农林科学

Journal of Applied Animal Research Pub Date : 2023-07-13 DOI: 10.1080/09712119.2023.2232000

E. R. Duarte, Brenda Marques de Paula, Thiago Alves Xavier dos Santos, Luís Miguel Gonçalves Fernandes, Valdo Soares Martins Júnior, Ramon Stefano Souza Silva, Fernanda de Oliveira Vincenzi, Luis Felipe Gonçalves, Bruna Freitas Souza, L. C. Geraseev, N. Oliveira, A. S. Chaves

{"title":"Nutrient intake and blood profile of Nellore calves supplemented with cellulolytic fungi from rumen","authors":"E. R. Duarte, Brenda Marques de Paula, Thiago Alves Xavier dos Santos, Luís Miguel Gonçalves Fernandes, Valdo Soares Martins Júnior, Ramon Stefano Souza Silva, Fernanda de Oliveira Vincenzi, Luis Felipe Gonçalves, Bruna Freitas Souza, L. C. Geraseev, N. Oliveira, A. S. Chaves","doi":"10.1080/09712119.2023.2232000","DOIUrl":"https://doi.org/10.1080/09712119.2023.2232000","url":null,"abstract":"ABSTRACT This study evaluates the effects of cellulolytic fungi from rumen on the nutrient intake and blood profile of Nellore calves. A diet was formulated with 56.79% lignified hay of Urochloa brizantha and 43.21% of concentrate. Sixteen Nellore calves were evaluated in completely randomized blocks using two calf groups: four males and four females. The first group was supplemented with a culture medium containing a mixture of Aspergillus terreus (VN 15 isolate) and Trichoderma longibrachiatum (VN 20 isolate). The second group received the sterile culture medium only. Ether extract ingestion was higher in the control calves; however, the supplemented calves showed a tendency to improve feed efficiency. No significant differences were detected in the blood profiles or serum biochemistry between the calf groups. Further research analyzing different dosages, adjusting the diet protein levels, and increasing the proportion of roughage could better elucidate the interference of these fungi on the performance and blood parameters of weaned Nellore calves.","PeriodicalId":15030,"journal":{"name":"Journal of Applied Animal Research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46363609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interspecific heavy metal variations and bioaccumulation in peafowl (Pavo cristatus) 孔雀(Pavo cristatus)种间重金属变异及生物积累

IF 1.4 4区农林科学

Journal of Applied Animal Research Pub Date : 2023-07-13 DOI: 10.1080/09712119.2023.2233587

Sajida Arooj, S. Naz, Aniqa Qaisar, Sania Satti, Alina Razzaq, A. Alrefaei, M. Albeshr, Mehwish Durrani, S. Dai, R. Khan

{"title":"Interspecific heavy metal variations and bioaccumulation in peafowl (Pavo cristatus)","authors":"Sajida Arooj, S. Naz, Aniqa Qaisar, Sania Satti, Alina Razzaq, A. Alrefaei, M. Albeshr, Mehwish Durrani, S. Dai, R. Khan","doi":"10.1080/09712119.2023.2233587","DOIUrl":"https://doi.org/10.1080/09712119.2023.2233587","url":null,"abstract":"ABSTRACT The present study was designed for biomonitoring of heavy metals such as lead (Pb), cadmium (Cd), chromium (Cr), zinc (Zn), nickel (Ni), manganese (Mn) and cobalt (Co) at three selected wildlife parks of Punjab. Soil, water and feed samples analysis revealed the high heavy metals contents in feed (21.59 ± 27.39 and 12.67 ± 23.13) followed by soil (11.80 ± 25.84 and 4.96 ± 10.95) and water (2.93 ± 4.48 and 1.11 ± 1.23) samples at Jallo Wildlife Park and Wildlife Park Bahawalnagar, respectively. At Wildlife Park Murree, heavy metals contamination was recorded highest in feed (10.45 ± 16.35), followed by water (6.26 ± 11.35) and soil samples (5.75 ± 9.54). Feathers samples at all sites showed the highest levels of heavy metals concentrations as 12.21 ± 25.69 at Jallo Wildlife Park, 11.50 ± 25.63 at Wildlife Park Bahawalnagar and 3.35 ± 4.81 at Wildlife Park Murree. Interspecific variation of heavy metals among samples and sites was recorded at P < 0.01, and bioaccumulation of heavy metals in the feathers of captive birds was found in high concentration, making them a good indicator of biomonitoring. In captivity, the birds feeding on homogenous diets and particular environmental conditions can better allow us to understand the bioaccumulation of polymetallic contamination, which can further be generalized to predict the risk of these toxic pollutants on public health.","PeriodicalId":15030,"journal":{"name":"Journal of Applied Animal Research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48510681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Polyphenols-rich polyherbal mixture attenuates hepatorenal impairment, dyslipidaemia, oxidative stress and inflammation in alloxan-induced diabetic rats 富含多酚的多元醇混合物减轻四氧嘧啶诱导的糖尿病大鼠的肝肾损伤、血脂异常、氧化应激和炎症

IF 1.4 4区农林科学

Journal of Applied Animal Research Pub Date : 2023-07-05 DOI: 10.1080/09712119.2023.2230754

B. Aslam, Asif Hussain, Zia-ud-Din Sindhu, S. Nigar, Ibad Ullah Jan, A. Alrefaei, M. Albeshr, V. Tufarelli, R. Khan

{"title":"Polyphenols-rich polyherbal mixture attenuates hepatorenal impairment, dyslipidaemia, oxidative stress and inflammation in alloxan-induced diabetic rats","authors":"B. Aslam, Asif Hussain, Zia-ud-Din Sindhu, S. Nigar, Ibad Ullah Jan, A. Alrefaei, M. Albeshr, V. Tufarelli, R. Khan","doi":"10.1080/09712119.2023.2230754","DOIUrl":"https://doi.org/10.1080/09712119.2023.2230754","url":null,"abstract":"ABSTRACT Effects of polyherbal mixture on hepatorenal injury and dyslipidaemia in alloxan-induced diabetic rats were evaluated. Alloxan monohydrate (120 mg/kg, i.p.) was injected into Wistar rats to induce diabetes. Animals were allotted to six groups (n = 6) and treatments were administered for consecutive six weeks as normal and diabetic controls, glibenclamide and polyherbal mixture (200, 400 and 600 mg/kg), respectively. Ameliorative effects of the polyherbal mixture were investigated by assessing FBG levels, changes in body and organ (liver and kidney) weights, biochemical parameters, oxidative stress along with inflammatory parameters in addition to histopathological examination of the liver and kidney. The results showed that alloxan-injected rats had significant (P < 0.05) hyperglycaemia in addition to elevated serum levels of hepatorenal injury indices (ALT, AST, ALP, bilirubin, total protein, albumin, creatinine, BUN and uric acid) and hyperlipidaemia evidenced by increased TC, TG, LDL-C, VLDL-C and decreased HDL-C levels. Furthermore, diabetes induction caused an increase in lipid peroxidation (MDA) and a reduction in antioxidant markers (SOD and CAT activities) as well as inflammation (TNF-α) in hepatic and renal tissues. Polyherbal mixture remarkably improved the aforementioned parameters in a dose-dependent manner. Histopathological findings supported the biochemical results. Conclusively, this study has provided novel insights into the efficacy of polyherbal mixtures in managing hyperglycaemia and its secondary complications in diabetes mellitus.","PeriodicalId":15030,"journal":{"name":"Journal of Applied Animal Research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2023-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43837604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3