Journal of Anatomy and Histopathology最新文献_第8页

Morphology of the epithelium of the fallopian tubes of rats under the influence of chronic low-intensity γ-radiation 慢性低强度γ辐射对大鼠输卵管上皮形态的影响

Journal of Anatomy and Histopathology Pub Date : 2023-01-13 DOI: 10.18499/2225-7357-2022-11-4-27-32

A. Pavlov, O. V. Ermakova, T. V. Korableva, O. A. Fokanova

{"title":"Morphology of the epithelium of the fallopian tubes of rats under the influence of chronic low-intensity γ-radiation","authors":"A. Pavlov, O. V. Ermakova, T. V. Korableva, O. A. Fokanova","doi":"10.18499/2225-7357-2022-11-4-27-32","DOIUrl":"https://doi.org/10.18499/2225-7357-2022-11-4-27-32","url":null,"abstract":"The purpose of the study was to investigate the functional morphology of the ciliary transport system of the fallopian tubes of sexually mature rats under the influence of chronic low-intensity γ-radiation.Material and methods. Using a complex technique of intravital microscopic observation, the motor activity of the ciliary apparatus was studied. The frequency of the main types of epithelial cells in the layer was determined on histological sections stained with hematoxylin and eosin. There was also determined morphometry of digitized images of cell structures (cell height, length of cilia) of the epithelial lining of the fallopian tubes of 16 female Wistar rats subjected to experimental chronic γ-irradiation for 55–70 days (total absorbed doses – 5 cGy and 50 cGy) and 8 control animals that were under natural background radiation.Results. The epithelium of the fallopian tubes in the control and experiment in rats contains three types of cells: ciliated, secretory and intercalary (cambial). Compared to the control of the irradiated rats the average height of ciliated cells and the length of cilia were decreased by 30% and 23%, respectively, at a total absorbed dose of 5 cGy and by 16% and 13% at 50 cGy (p 18% (p recorded, while the dimensional characteristics of secretory cells did not significantly differ from the control (p>0,05).Conclusions. The effects of chronic low-intensity γ-radiation on the epithelial lining of the fallopian tubes can be clearly manifested at the level of physiological reactions of cells; irradiation at a minimum dose of 5 cGy is already capable of causing atrophic rearrangements and dysfunction of the ciliated epithelium. The results obtained indicate a high radiosensitivity of the studied tissue elements and make it possible to consider chronic ionizing radiation as a potential risk factor disrupting the structure and function of the epithelial lining of the organ.","PeriodicalId":15028,"journal":{"name":"Journal of Anatomy and Histopathology","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78915811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Morphological characteristics and expression of the S-100 protein in Purkinje cells of the cerebellum of a young and senile human S-100蛋白在青年人和老年人小脑浦肯野细胞中的形态特征和表达

Journal of Anatomy and Histopathology Pub Date : 2023-01-13 DOI: 10.18499/2225-7357-2022-11-4-9-14

A. A. Balandin, L. M. Zheleznov, I. A. Balandina

{"title":"Morphological characteristics and expression of the S-100 protein in Purkinje cells of the cerebellum of a young and senile human","authors":"A. A. Balandin, L. M. Zheleznov, I. A. Balandina","doi":"10.18499/2225-7357-2022-11-4-9-14","DOIUrl":"https://doi.org/10.18499/2225-7357-2022-11-4-9-14","url":null,"abstract":"The problem of aging of the human body and the prevention of age-associated diseases in modern scientific literature is devoted to many studies. Researchers are showing increased interest in the aging of the cerebellum. Purkinje cells, which form the ganglionic layer of the cerebellar cortex, are considered to be very sensitive to various influences.The aim is to reveal the morphofunctional features of the Purkinje cells of the human cerebellum in the senile age in comparison with the young age.Material and methods. Morphological study of the cerebellum of 59 men and 52 women, right-handed, with anamnestic data that excluded diseases and injuries of the organs of the central and peripheral nervous system, as well as alcohol or drug addiction, was carried out during autopsy. The material for the study was taken from the region of the inferior semilunar lobule of the cerebellum. The studied material was divided into two groups: group I (n=59) included samples obtained from 31 men and 28 young women (from 25 to 32 years old inclusive), group II (n=52) – from 28 men and 24 women of senile age (from 79 to 88 years inclusive). We used general and neurohistological, immunohistochemical and morphometric research methods. Morphological assessment of Purkinje cells was carried out and the distance between their bodies was determined. An immunohistochemical study used a panel of antibodies to the S-100 protein.Results. A comparative analysis of the data obtained showed a statistically significant predominance of the distance between the bodies of Purkinje cells in the elderly compared to the young. Immunohistochemical study revealed an increase in the number of S-100-immunopositive Purkinje cells in old age.Conclusion. New data have been obtained on the age-related structural transformation of the cytoarchitectonics of the human cerebellar nervous tissue, which must be taken into account when studying age-associated diseases and movement coordination disorders.","PeriodicalId":15028,"journal":{"name":"Journal of Anatomy and Histopathology","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74390403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Journal of Anatomy and Histopathology Pub Date : 2023-01-13 DOI: 10.18499/2225-7357-2022-11-4-15-19

A. B. Gur'eva, V. Alekseeva, T. V. Sleptsova

{"title":"Age-related features of somatometric parameters of Yakut men according to Heath–Carter","authors":"A. B. Gur'eva, V. Alekseeva, T. V. Sleptsova","doi":"10.18499/2225-7357-2022-11-4-15-19","DOIUrl":"https://doi.org/10.18499/2225-7357-2022-11-4-15-19","url":null,"abstract":"The aim of the study was to identify the features of the somatometric parameters of Yakut men in the youthful and second period of adulthood according to Heath–Carter.Material and methods. 167 young men and 41 men of the second period of mature age of the Yakut nationality were examined. The examination included anthropometric measurements and bioimpedance analysis of the body BMI and waist-to-hip ratio were calculated. Somatotyping according to Heath–Carter was carried out on the basis of ecto-, meso- and endomorphic scores, which are included in the bioimpedancemetry protocol. Statistical processing of the obtained data was carried out using the SPSS 17.0 application package. The normality of the distribution of parameters was determined by the Kolmogorov–Smirnov criterion. Mean (M) and standard deviation (SD) were calculated, and intergroup differences were assessed using Student's t-test.Results. The study revealed age differences in terms of length, weight and body composition. Significantly large values of body length, relative parameters of skeletal muscle mass and active cell mass were found in young men. Mature men had significantly higher body weight values, absolute and relative indicators of fat mass, absolute values of active cell mass. According to BMI, overweight was detected in 6.6%, obesity - in 3.0% of young men. Among men of mature age, overweight was determined in 54.2%, obesity - in 27.0%. A high index of the ratio of waist circumference to hip circumference was found in 4.8% of boys and 58.5% of men. The distribution of somatotypes according to Heath-Carter revealed that young men in 100% of cases had a mesectomorphic somatotype. In mature men, the mesectomorphic type was also the predominant somatotype (95.8%). In 4.2% of men of mature age, a balanced ectomorphic type was determined. The absence of variability in body types suggests that the mesectomorphic somatotype is the most adapted to living in the extreme natural and climatic conditions of Yakutia.","PeriodicalId":15028,"journal":{"name":"Journal of Anatomy and Histopathology","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76013082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of the immunohistochemical and ultrastructural studies of the white rats sensorimotor cortex synaptic terminals reaction to common carotid arteries ligation 大鼠感觉运动皮层突触末梢对颈总动脉结扎反应的免疫组织化学和超微结构研究

Journal of Anatomy and Histopathology Pub Date : 2022-10-11 DOI: 10.18499/2225-7357-2022-11-3-65-74

S. Stepanov, L. M. Makar'eva, V. A. Akulinin, M. Korzhuk, A. Y. Shoronova, D. Avdeev, I. G. Tsuskman, A. V. Slobodskaya

引用次数: 3

Matrix metalloproteinases in extracellular matrix remodeling: molecular, cellular and tissue aspects 基质金属蛋白酶在细胞外基质重塑中的作用:分子、细胞和组织方面

Journal of Anatomy and Histopathology Pub Date : 2022-10-11 DOI: 10.18499/2225-7357-2022-11-3-93-108

V. V. Shishkina, L. N. Antakova, S. Zolotareva, D. Atyakshin

引用次数: 1

Expression of 5-HT1A receptors in skin of rats under dark deprivation 暗剥夺大鼠皮肤5-HT1A受体的表达

Journal of Anatomy and Histopathology Pub Date : 2022-10-11 DOI: 10.18499/2225-7357-2022-11-3-57-64

I. S. Sobolevskaya, M. I. Krasnobaeva, O. D. Myadelets

引用次数: 0

Macrophages of the respiratory division of the lungs of rats after a single parenteral injection of silicon dioxide nanoparticles of various sizes 单次肠外注射不同大小二氧化硅纳米颗粒后大鼠肺呼吸分裂的巨噬细胞

Journal of Anatomy and Histopathology Pub Date : 2022-10-11 DOI: 10.18499/2225-7357-2022-11-3-114-117

G. Yukina, E. Sukhorukova, I. Polovnikov, E. A. Kryzhanovskaya, S. Zhuravskii

引用次数: 0

2D geometric model of the human femoral neck in frontal projection 人股骨颈正面投影的二维几何模型

Journal of Anatomy and Histopathology Pub Date : 2022-10-11 DOI: 10.18499/2225-7357-2022-11-3-75-81

S. A. Teplov, A. Pavlov, A. V. El'tsov, I. Bakharev, K. O. Slabachkov

引用次数: 0

Assessment of the content of neuroendocrine cells in the gastric mucosa in patients with autoimmune gastritis 自身免疫性胃炎患者胃黏膜神经内分泌细胞含量的评价

Journal of Anatomy and Histopathology Pub Date : 2022-10-11 DOI: 10.18499/2225-7357-2022-11-3-109-113

D. P. Nagornaya, S. D. Sarkisyan, O. Vasil'eva, K. A. Il'icheva, A. S. Tertychnyi

引用次数: 1

Morphofunctional features of the uterus of rodents: morphogenesis, structure, cyclic changes, impact of various negative environmental factors 啮齿类动物子宫的形态功能特征:形态发生、结构、循环变化、各种负面环境因素的影响

Journal of Anatomy and Histopathology Pub Date : 2022-10-11 DOI: 10.18499/2225-7357-2022-11-3-82-92

N. Shevlyuk, E. V. Blinova

引用次数: 1