Journal of Anesthesia最新文献

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Using multi-level regression to determine associations and estimate causes and effects in clinical anesthesia due to patient, practitioner and hospital or health system practice variability 利用多层次回归确定相关性,并估算临床麻醉中因患者、从业人员、医院或医疗系统的实践差异而产生的原因和影响
IF 2.8 3区 医学
Journal of Anesthesia Pub Date : 2024-09-18 DOI: 10.1007/s00540-024-03408-3
Kazuyoshi Aoyama, Alan Yang, Ruxandra Pinto, Joel G. Ray, Andrea Hill, Damon C. Scales, Robert A. Fowler
{"title":"Using multi-level regression to determine associations and estimate causes and effects in clinical anesthesia due to patient, practitioner and hospital or health system practice variability","authors":"Kazuyoshi Aoyama, Alan Yang, Ruxandra Pinto, Joel G. Ray, Andrea Hill, Damon C. Scales, Robert A. Fowler","doi":"10.1007/s00540-024-03408-3","DOIUrl":"https://doi.org/10.1007/s00540-024-03408-3","url":null,"abstract":"<p>In this research methods tutorial of clinical anesthesia, we will explore techniques to estimate the influence of a myriad of factors on patient outcomes. Big data that contain information on <i>patients</i>, treated by <i>individual anesthesiologists and surgical teams</i>, at different <i>hospitals</i>, have an inherent multi-level data structure (Fig. 1). While researchers often attempt to determine the association between patient factors and outcomes, that does not provide clinicians with the whole story. Patient care is <i>clustered</i> together according to clinicians and hospitals where they receive treatment. Therefore, multi-level regression models are needed to validly estimate the influence of each factor at each level. In addition, we will explore how to estimate the influence that <i>variability</i>—for example, one anesthesiologist deciding to do one thing, while another takes a different approach—has on outcomes for patients, using the <i>intra-class correlation coefficient</i> for continuous outcomes and the <i>median odds ratio</i> for binary outcomes. From this tutorial, you should acquire a clearer understanding of how to perform and interpret multi-level regression modeling and estimate the influence of variable clinical practices on patient outcomes in order to answer common but complex clinical questions.</p>","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142248413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of the effectiveness of preoperative intubation simulation using a custom-made simulator for pediatric patients with difficult airway: a pilot study 使用定制模拟器为气道困难的儿科患者进行术前插管模拟的有效性调查:一项试点研究
IF 2.8 3区 医学
Journal of Anesthesia Pub Date : 2024-09-15 DOI: 10.1007/s00540-024-03407-4
Tomoyuki Kanazawa
{"title":"Investigation of the effectiveness of preoperative intubation simulation using a custom-made simulator for pediatric patients with difficult airway: a pilot study","authors":"Tomoyuki Kanazawa","doi":"10.1007/s00540-024-03407-4","DOIUrl":"https://doi.org/10.1007/s00540-024-03407-4","url":null,"abstract":"<p>The purpose of this study is to investigate whether preoperative intubation simulation using custom-made simulator is useful during anesthesia induction for the children who have difficult airway. We included the children under 15 years of age who have difficult airway which had been already known. Prior to the scheduled surgery, CT imaging was performed and a 3D reconstruction of the face from the chest was performed. Then custom-made airway simulator was made. We tried to intubate custom-made simulator of patients preoperatively. We planned how to intubate the patient for anesthesia induction from the result of intubation simulation. The findings of direct laryngoscopy were compared with the findings during intubation. Three patients were included in this study. It took up to 3 weeks to create a simulator, which was difficult due to time constraints to accommodate emergency surgeries. Simulation findings correlated well with findings during anesthesia induction. There were no cases of severe hypotension or hypoxia during induction of anesthesia with the planned intubation method. In conclusion, preoperative intubation simulation using custom-made simulator may be useful for the patients who have difficult airway.</p>","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142248461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of lung-recruitment maneuver on postoperative shoulder pain in patients undergoing laparoscopic cholecystectomy: a randomized controlled trial 肺复张法对腹腔镜胆囊切除术患者术后肩痛的影响:随机对照试验
IF 2.8 3区 医学
Journal of Anesthesia Pub Date : 2024-09-14 DOI: 10.1007/s00540-024-03403-8
Yeon Ji Noh, Eun Jin Kwon, Yu Jeong Bang, So Jeong Yoon, Hyun Ji Hwang, Heejoon Jeong, Sangmin Maria Lee, Young Hee Shin
{"title":"The effect of lung-recruitment maneuver on postoperative shoulder pain in patients undergoing laparoscopic cholecystectomy: a randomized controlled trial","authors":"Yeon Ji Noh, Eun Jin Kwon, Yu Jeong Bang, So Jeong Yoon, Hyun Ji Hwang, Heejoon Jeong, Sangmin Maria Lee, Young Hee Shin","doi":"10.1007/s00540-024-03403-8","DOIUrl":"https://doi.org/10.1007/s00540-024-03403-8","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose</h3><p>Lung-recruitment maneuvers (LRM) have been shown to reduce postoperative pain after laparoscopic surgery. This study aimed to investigate the association of LRM with the incidence of shoulder pain after laparoscopic cholecystectomy.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>A randomized controlled study was conducted with 110 patients undergoing elective laparoscopic cholecystectomy from July 2022 to March 2023. Participants were randomized to receive either routine exsufflation or LRM at pneumoperitoneum release. The postoperative shoulder pain and abdominal pain were assessed at 1, 4, 6, 12, and 24 h after surgery using a numeric rating scale. Analgesic consumption and postoperative nausea or vomiting (PONV) were evaluated during the first 24 h after surgery.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>The incidence of shoulder pain during the first 24 h after surgery was significantly lower in the LRM group compared to the control group (26.9 vs. 59.3%; <i>P</i> = 0.001). The median [interquartile range] score of worst shoulder pain was significantly lower compared to the control group (3 [2–3] vs 4 [3–5.5]; <i>P</i> = 0.003). Participants in the LRM group showed reduced abdominal pain at rest at 4 and 24 h after surgery, and experienced significantly lower intensities of abdominal pain during mobilization at all time points over 24 h after surgery. There were no significant differences in opioid consumption or the incidence of PONV between the groups.</p><h3 data-test=\"abstract-sub-heading\">Conclusions</h3><p>LRM reduces both the incidence and intensity of shoulder pain during 24 h after laparoscopic cholecystectomy. Additionally, LRM was associated with reduced intensity of abdominal pain during mobilization over the study period.</p>","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142248462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk of postoperative pneumonia after extubation with the positive pressure versus normal pressure technique: a single-center retrospective observational study 采用正压与常压技术拔管后术后肺炎的风险:一项单中心回顾性观察研究
IF 2.8 3区 医学
Journal of Anesthesia Pub Date : 2024-09-12 DOI: 10.1007/s00540-024-03409-2
Kensuke Shimada, Masahiko Gosho, Tomohiro Ohigashi, Keitaro Kume, Takahiro Yano, Ryota Ishii, Kazushi Maruo, Ryota Inokuchi, Masao Iwagami, Hiroshi Ueda, Makoto Tanaka, Masaru Sanuki, Nanako Tamiya
{"title":"Risk of postoperative pneumonia after extubation with the positive pressure versus normal pressure technique: a single-center retrospective observational study","authors":"Kensuke Shimada, Masahiko Gosho, Tomohiro Ohigashi, Keitaro Kume, Takahiro Yano, Ryota Ishii, Kazushi Maruo, Ryota Inokuchi, Masao Iwagami, Hiroshi Ueda, Makoto Tanaka, Masaru Sanuki, Nanako Tamiya","doi":"10.1007/s00540-024-03409-2","DOIUrl":"https://doi.org/10.1007/s00540-024-03409-2","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose</h3><p>A normal pressure extubation technique (no lung inflation before extubation), proposed by the Japanese Society of Anesthesiologists to prevent droplet infection during the coronavirus disease 2019 (COVID-19) pandemic, could theoretically increase postoperative pneumonia incidence compared with a positive pressure extubation technique (lung inflation before extubation). However, the normal pressure extubation technique has not been adequately evaluated. This study compared postoperative pneumonia incidence between positive and normal pressure extubation techniques using a dataset from the University of Tsukuba Hospital.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>In our hospital, the extubation methods changed from positive to normal pressure extubation techniques on March 3, 2020 due to the COVID-19 pandemic. Thus, we compared the risk of postoperative pneumonia between the positive (April 1, 2017 to December 31, 2019) and normal pressure extubation techniques (March 3, 2020 to March 31, 2022) using propensity score analyses. Postoperative pneumonia was defined using the International Classification of Diseases, 10th Edition (ICD-10) codes (J13–J18), and we reviewed the medical records of patients flagged with these ICD-10 codes (preoperative pneumonia and ICD-10 codes for prophylactic antibiotic prescriptions for pneumonia).</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>We identified 20,011 surgeries, including 11,920 in the positive pressure extubation group (mean age 48.2 years, standard deviation [SD] 25.2 years) and 8,091 in the normal pressure extubation group (mean age 47.8 years, SD 25.8 years). The postoperative pneumonia incidences were 0.19% (23/11,920) and 0.17% (14/8,091) in the positive and normal pressure extubation groups, respectively. The propensity score analysis using inverse probability weighting revealed no significant difference in postoperative pneumonia incidence between the two groups (adjusted odds ratio 0.98, 95% confidence interval 0.50 to 1.91, <i>P</i> = 0.94).</p><h3 data-test=\"abstract-sub-heading\">Conclusions</h3><p>These results indicated no increased risk of postoperative pneumonia associated with the normal pressure extubation technique compared with the positive pressure extubation technique.</p><h3 data-test=\"abstract-sub-heading\">Clinical trial number</h3><p>Clinical trial number: UMIN000048589 https://center6.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000055364</p>","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142248460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accuracy of non-invasive core temperature monitoring in infant and toddler patients: a prospective observational study 婴幼儿患者无创核心体温监测的准确性:前瞻性观察研究
IF 2.8 3区 医学
Journal of Anesthesia Pub Date : 2024-09-11 DOI: 10.1007/s00540-024-03404-7
Tasuku Fujii, Masashi Takakura, Tomoya Taniguchi, Kimitoshi Nishiwaki
{"title":"Accuracy of non-invasive core temperature monitoring in infant and toddler patients: a prospective observational study","authors":"Tasuku Fujii, Masashi Takakura, Tomoya Taniguchi, Kimitoshi Nishiwaki","doi":"10.1007/s00540-024-03404-7","DOIUrl":"https://doi.org/10.1007/s00540-024-03404-7","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose</h3><p>Careful perioperative temperature management is important because it influences clinical outcomes. In pediatric patients, the esophageal temperature is the most accurate indicator of core temperature. However, it requires probe insertion into the body cavity, which is mildly invasive. Therefore, a non-invasive easily and continuously temperature monitor system is ideal. This study aimed to assess the accuracy of Temple Touch Pro™ (TTP), a non-invasive temperature monitoring using the heat flux technique, compared with esophageal (Tesoph) and rectal (Trect) temperature measurements in pediatric patients, especially in infants and toddlers.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>This single-center prospective observational study included 40 pediatric patients (&lt; 3 years old) who underwent elective non-cardiac surgery. The accuracy of TTP was analyzed using Bland–Altman analysis and compared with Tesoph or Trect temperature measurements. The error was within ± 0.5 °C and was considered clinically acceptable.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>The bias ± precision between TTP and Tesoph was 0.09 ± 0.28 °C, and 95% limits of agreement were – 0.48 to 0.65 °C (error within ± 0.5 °C: 94.0%). The bias ± precision between TTP and Trect was 0.41 ± 0.38 °C and 95% limits of agreement were – 0.35 to 1.17 °C (error within ± 0.5 °C: 68.5%). In infants, bias ± precision with 95% limits of agreement were 0.10 ± 0.30 °C with – 0.50 to 0.69 °C (TTP vs. Tesoph) and 0.35 ± 0.29 °C with – 0.23 to 0.92 °C (TTP vs. Trect).</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>Core temperature measurements using TTP in infants and toddlers were more accurate with Tesoph than with Trect. In the future, non-invasive TTP temperature monitoring will help perioperative temperature management in pediatric patients.</p>","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142227925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Decrease of the peak heights of EEG bicoherence indicated insufficiency of analgesia during surgery under general anesthesia. 脑电图双相干峰值高度的降低表明全身麻醉手术期间镇痛不足。
IF 2.8 3区 医学
Journal of Anesthesia Pub Date : 2024-09-09 DOI: 10.1007/s00540-024-03406-5
Rieko Uno, Satoshi Hagihira, Satoshi Aihara, Takahiko Kamibayashi
{"title":"Decrease of the peak heights of EEG bicoherence indicated insufficiency of analgesia during surgery under general anesthesia.","authors":"Rieko Uno, Satoshi Hagihira, Satoshi Aihara, Takahiko Kamibayashi","doi":"10.1007/s00540-024-03406-5","DOIUrl":"https://doi.org/10.1007/s00540-024-03406-5","url":null,"abstract":"<p><strong>Background: </strong>Studies show that the two peak heights of electroencephalographic bicoherence (pBIC-high, pBIC-low) decrease after incision and are restored by fentanyl administration. We investigated whether pBICs are good indicators for adequacy of analgesia during surgery.</p><p><strong>Methods: </strong>After local ethical committee approval, we enrolled 50 patients (27-65 years, ASA-PS I or II) who were scheduled elective surgery. Besides standard anesthesia monitors, to assess pBICs, we used a BIS monitor and freeware Bispectrum Analyzer for A2000. Fentanyl 5 µg/kg was completely administered before incision, and anesthesia was maintained with sevoflurane. After skin incision, when the peak of pBIC-high or pBIC-low decreased by 10% in absolute value (named LT10-high and LT10-low groups in order) or when either peak decreased to below 20% (BL20-high and BL20-low groups), an additional 1 g/kg of fentanyl was administered to examine its effect on the peak that showed a decrease.</p><p><strong>Results: </strong>The mean values and standard deviation for pBIC-high 5 min before fentanyl administration, at the time of fentanyl administration, and 5 min after fentanyl administration for LT10-high group were 39.8% (10.9%), 26.9% (10.5%), and 35.7% (12.5%). And those for pBIC-low for LT10-low group were 39.5% (6.0%), 26.8% (6.4%) and 35.0% (7.0%). Those for pBIC-high for BL20-high group were 26.3% (5.6%), 16.5% (2.6%), and 25.7% (7.0%). And those for pBIC-low for BL20-low group were 26.7% (4.8%), 17.4% (1.8%) and 26.9% (5.7%), respectively. Meanwhile, at these trigger points, hemodynamic parameters didn't show significant changes.</p><p><strong>Conclusion: </strong>Superior to standard anesthesia monitoring, pBICs are better indicators of analgesia during surgery.</p><p><strong>Trial registry: </strong>Clinical trial Number and registry URL: UMIN ID: UMIN000042843 https://center6.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno  = R000048907.</p>","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142154060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pregnancy ameliorates neuropathic pain through suppression of microglia and upregulation of the δ-opioid receptor in the anterior cingulate cortex in late-pregnant mice. 妊娠通过抑制小胶质细胞和上调妊娠晚期小鼠前扣带回皮层中的δ-阿片受体来改善神经性疼痛。
IF 2.8 3区 医学
Journal of Anesthesia Pub Date : 2024-09-08 DOI: 10.1007/s00540-024-03402-9
Atsushi Sawada, Michiaki Yamakage
{"title":"Pregnancy ameliorates neuropathic pain through suppression of microglia and upregulation of the δ-opioid receptor in the anterior cingulate cortex in late-pregnant mice.","authors":"Atsushi Sawada, Michiaki Yamakage","doi":"10.1007/s00540-024-03402-9","DOIUrl":"https://doi.org/10.1007/s00540-024-03402-9","url":null,"abstract":"<p><strong>Purpose: </strong>Pregnancy-induced analgesia develops in late pregnancy, but its mechanisms are unclear. The anterior cingulate cortex (ACC) plays a key role in the pathogenesis of neuropathic pain. The authors hypothesized that pregnancy-induced analgesia ameliorates neuropathic pain by suppressing activation of microglia and the expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, and by upregulating opioid receptors in the ACC in late-pregnant mice.</p><p><strong>Methods: </strong>Neuropathic pain was induced in non-pregnant (NP) or pregnant (P) C57BL/6JJmsSlc female mice by partial sciatic nerve ligation (PSNL). The nociceptive response was evaluated by mechanical allodynia and activation of microglia in the ACC was evaluated by immunohistochemistry. The expressions of phosphorylated AMPA receptors and opioid receptors in the ACC were evaluated by immunoblotting.</p><p><strong>Results: </strong>In von Frey reflex tests, NP-PSNL-treated mice showed a lower 50% paw-withdrawal threshold than NP-Naïve mice on experimental day 9. No difference in 50% paw-withdrawal threshold was found among the NP-Naïve, NP-Sham, P-Sham, and P-PSNL-treated mice. The number of microglia in the ACC was significantly increased in NP-PSNL-treated mice compared to NP-Sham mice. Immunoblotting showed significantly increased expression of phosphorylated AMPA receptor subunit GluR1 at Ser831 in NP-PSNL-treated mice compared to NP-Sham mice. Immunoblotting also showed significantly increased δ-opioid receptor in the ACC in P-Sham and P-PSNL-treated mice compared to NP-Sham mice.</p><p><strong>Conclusion: </strong>Pregnancy-induced analgesia ameliorated neuropathic pain by suppressing activation of microglia and the expression of phosphorylated AMPA receptor subunit GluR1 at Ser831, and by upregulation of the δ-opioid receptor in the ACC in late-pregnant mice.</p>","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142154061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lower extremity pain and/or numbness after laparoscopic surgery and robot-assisted surgery in the lithotomy position combined with the Trendelenburg position. 以平卧位结合 Trendelenburg 体位进行腹腔镜手术和机器人辅助手术后的下肢疼痛和/或麻木。
IF 2.8 3区 医学
Journal of Anesthesia Pub Date : 2024-09-01 DOI: 10.1007/s00540-024-03399-1
Keiko Yamasaki, Keisuke Fujii, Yasuo Kohjimoto, Kenji Matsuda, Hiromitsu Iwamoto, Manabu Kawai, Ke Wan, Tomoyuki Kawamata
{"title":"Lower extremity pain and/or numbness after laparoscopic surgery and robot-assisted surgery in the lithotomy position combined with the Trendelenburg position.","authors":"Keiko Yamasaki, Keisuke Fujii, Yasuo Kohjimoto, Kenji Matsuda, Hiromitsu Iwamoto, Manabu Kawai, Ke Wan, Tomoyuki Kawamata","doi":"10.1007/s00540-024-03399-1","DOIUrl":"https://doi.org/10.1007/s00540-024-03399-1","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to investigate the incidence and risk factors of lower extremity pain and/or numbness after laparoscopic colorectal surgery and robot-assisted laparoscopic radical prostatectomy in the lithotomy position combined with the Trendelenburg position. The relationship between creatine kinase (CK) levels and lower extremity pain and/or numbness was also investigated.</p><p><strong>Methods: </strong>We retrospectively reviewed adult patients who underwent laparoscopic colorectal surgery and robot-assisted laparoscopic radical prostatectomy in the lithotomy position combined with the Trendelenburg position between May 2015 and April 2020. Logistic regression analysis was used to identify risk factors of lower extremity pain and/or numbness. Preoperative and postoperative CK levels were compared in patients with and those without lower extremity pain and/or numbness.</p><p><strong>Results: </strong>Among 940 patients, 1.9% experienced lower extremity pain and/or numbness postoperatively. The incidences of lower extremity pain and/or numbness after laparoscopic colorectal surgery and after robot-assisted laparoscopic radical prostatectomy were 1.7% and 2.1%, respectively. Multivariate logistic regression analysis revealed that only duration of surgery > 4 h (odds ratio = 3.144, 95% CI: 1.102-8.969, p = 0.032) was a significant predictor of lower extremity pain and/or numbness. Postoperative median CK level in patients with lower extremity pain and/or numbness was significantly higher than that in patients without lower extremity pain and/or numbness.</p><p><strong>Conclusion: </strong>The incidence of lower extremity pain and/or numbness after laparoscopic colorectal surgery was comparable to that after robot-assisted laparoscopic radical prostatectomy. Prolonged duration of surgery contributed to lower extremity pain and/or numbness. Significantly elevated CK levels in patients with lower extremity pain and/or numbness suggest the involvement of muscle injury in these symptoms.</p>","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142107684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recommendation for the practice of total intravenous anesthesia. 关于全静脉麻醉实践的建议。
IF 2.8 3区 医学
Journal of Anesthesia Pub Date : 2024-09-01 DOI: 10.1007/s00540-024-03398-2
Shinju Obara, Kotoe Kamata, Masakazu Nakao, Shigeki Yamaguchi, Shuya Kiyama
{"title":"Recommendation for the practice of total intravenous anesthesia.","authors":"Shinju Obara, Kotoe Kamata, Masakazu Nakao, Shigeki Yamaguchi, Shuya Kiyama","doi":"10.1007/s00540-024-03398-2","DOIUrl":"https://doi.org/10.1007/s00540-024-03398-2","url":null,"abstract":"<p><p>This Recommendation was developed by the Japanese Society of Intravenous Anesthesia Recommendation Making Working Group (JSIVA-WG) to promote the safe and effective practice of total intravenous anesthesia (TIVA), tailored to the current situation in Japan. It presents a policy validated by the members of JSIVA-WG and a review committee for practical anesthesia management. Anesthesiologists should acquire and maintain the necessary knowledge and skills to be able to administer TIVA properly. A secure venous access is critically important for TIVA. To visualize and understand the pharmacokinetics of intravenous anesthetics, use of real-time pharmacokinetic simulations is strongly recommended. Syringe pumps are essential for the infusion of intravenous anesthetics, which should be prepared according to the rules of each individual anesthesia department, particularly with regard to dilution. Syringes should be clearly labeled with content and drug concentration. When managing TIVA, particularly with the use of muscle relaxants, monitoring processed electroencephalogram (EEG) is advisable. However, the depth of sedation/anesthesia must be assessed comprehensively using various parameters, rather than simply relying on a single EEG index. TIVA should be swiftly changed to an alternative method that includes inhalation anesthesia if necessary. Use of antagonists at emergence may be associated with re-sedation risk. Casual administration of antagonists and sending patients back to surgical wards without careful observation are not acceptable.</p>","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142107685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hypotension in cesarean delivery: questions and answers. 剖宫产术中的低血压:问题与解答。
IF 2.8 3区 医学
Journal of Anesthesia Pub Date : 2024-08-31 DOI: 10.1007/s00540-024-03400-x
Ahmed M Hasanin, Rana M Zaki, Maha Mostafa
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