Journal of Anesthesia最新文献

{"title":"Neuropathic pain after peripheral nerve injury in rats: a model using sciatic nerve clamping.","authors":"Michio Kumagai, Shigekazu Sugino, Toru Murakami, Hideaki Obata, Masanori Yamauchi","doi":"10.1007/s00540-025-03541-7","DOIUrl":"10.1007/s00540-025-03541-7","url":null,"abstract":"<p><p>Various preclinical rodent models have been established and utilized to elucidate the mechanisms underlying neuropathic pain. However, the utility of existing major models faces challenges, such as reproducibility and surgical complexity. Here, we introduce a new rat model of neuropathic pain created by simply clamping the sciatic nerve for 10 min. First, we investigated pain-related behavior in 12 male Wistar rats after surgery to clamp the sciatic nerve that induced mechanical allodynia for 21 days and thermal hyperalgesia for 7 days (2-way ANOVA compared with sham-operated rats, p < 0.01). We observed only small interindividual differences in response to stimuli among the rats after sciatic nerve clamp surgery. The L5 dorsal root ganglion and spinal dorsal horn of the other 14 rats were subsequently sectioned and stained for Atf3 and Iba-1 immunoreactivity, respectively. Compared with sham surgery, nerve clamping induced peripheral and central sensitization (Mann-Whitney U test, p < 0.01). This new preclinical rat model of neuropathic pain offers procedural simplicity and high reproducibility.</p>","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":" ","pages":"815-820"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12464118/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144768675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to Kawasaki et al. randomized clinical trial.","authors":"Shuyu Zhang","doi":"10.1007/s00540-025-03542-6","DOIUrl":"10.1007/s00540-025-03542-6","url":null,"abstract":"","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":" ","pages":"833-834"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144637086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to the letter by Triwiyanto.","authors":"Koji Sato, Junji Genda, Seiki Deguchi, Takumi Taniguchi","doi":"10.1007/s00540-025-03514-w","DOIUrl":"10.1007/s00540-025-03514-w","url":null,"abstract":"","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":" ","pages":"825-826"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on Itaya et al.'s trial of anesthetic agents.","authors":"Itsuki Terao","doi":"10.1007/s00540-025-03516-8","DOIUrl":"10.1007/s00540-025-03516-8","url":null,"abstract":"","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":" ","pages":"827"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"General anesthesia/general anesthetics: Journal of Anesthesia symposium 2025.","authors":"Kenichi Masui, Kotoe Kamata, Ayako Tojo, Michiyoshi Sanuki, Yoshiki Nakajima, Shuya Kiyama","doi":"10.1007/s00540-025-03591-x","DOIUrl":"https://doi.org/10.1007/s00540-025-03591-x","url":null,"abstract":"<p><p>Key interventions for anesthesia patients include administering drugs, infusing fluids and blood, and providing artificial ventilation. As general anesthetics are always administered to patients undergoing general anesthesia, anesthetists need to be familiar with the fundamentals and the latest issues of general anesthesia/anesthetics. The Journal of Anesthesia symposium 2025 aimed to discuss fundamental topics and environmental issues related to general anesthesia and anesthetics. In this symposium, we had following topics: (1) patient outcomes of general anesthesia observed outside the operating room after the surgery, (2) updated information on the benefits and limitations of intravenous and inhalational anesthesia, (3) the environmental impact and recommended actions, and (4) potential reasons for not selecting intravenous anesthesia despite its apparent benefits for anesthetized patients.</p>","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145206526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Executive summary of the guideline for prescribing opioid analgesics for chronic non-cancer pain (third edition) by the Japan Society of Pain Clinicians.","authors":"Akifumi Kanai, Masako Iseki, Hiroki Iida, Shigeki Yamaguchi, Ayano Oiwa, Hiroshi Yonekura, Narihito Iwashita, Hiroshi Ueno, Yoshiyuki Kimura, Toshifumi Takasusuki, Keisuke Yamaguchi, Shie Iida, Hiroko Ikemiya, Rina Oya, Yoko Sugiyama, Kumiko Tanabe, Ayano Taniguchi, Yoshiyasu Hattammaru, Maki Mizogami, Shinobu Yamaguchi, Keiko Yamada, Sei Fukui","doi":"10.1007/s00540-025-03559-x","DOIUrl":"10.1007/s00540-025-03559-x","url":null,"abstract":"<p><p>Opioid analgesics are powerful pain relievers, but inappropriate use can cause a variety of problems. Especially, in chronic non-cancer pain, inappropriate use of opioid analgesics might fail to improve or even worsen the quality of life and activities of daily living of patients impaired by pain. The Japan Society of Pain Clinicians has developed the Guidelines for Prescribing Opioid Analgesics for Chronic Non-cancer Pain (Third Edition), which answers basic clinical questions concerning opioid management as summary statements in accordance with the most recent scientific evidence and expert opinion. The guidelines emphasize patient selection (e.g., obvious organic cause of the persistent pain, low risk of psychosocial factors, pain refractory to non-opioid therapies, and good adherence to medication). Furthermore, patients should be treated with an oral dose of 90 morphine milligram equivalents/day as the upper limit and target duration of 3-6 months. For pain in cancer survivors that is not directly caused by cancer, such as pain after treatment or pain associated with complications or pre-existing conditions, these guidelines should be followed.</p>","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":" ","pages":"677-702"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12464052/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144821496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of postoperative pain in neonatal intensive care units in Japan.","authors":"Aya Shimizu, Mio Ozawa, Akio Kubota, Toshie Yamazaki, Takako Tamura, Satoshi Toyama, Takeshi Arimitsu, Rie Fukuhara","doi":"10.1007/s00540-025-03497-8","DOIUrl":"10.1007/s00540-025-03497-8","url":null,"abstract":"<p><p>Neonatal postoperative pain management in Japan is not as standardized as bedside procedural pain, where evidence-based guidelines are widespread, which causes a knowledge gap. To identify postoperative pain management issues, we analyzed the anonymous survey online or by mail by neonatologists or head nurses in 89 Japan's neonatal intensive care units (levels III and IV). Although 79 units (88.8%) required recommendation for postoperative pain management, 11 units (12.4%) used a pain scale for pain assessment, 35 units (39.3%) had evaluated and recorded the pain assessment, 27 units (30%) had updated the postoperative pain management plan, less than bedside procedure, and 14 units (15.7%) had made a preoperative pain management plan. Pain management among neonatal nurses and neonatologists and pediatric surgeons and anesthesiologists have been in three units (3.4%) for preoperative, and in six units (6.7%), and postoperative pain management consult was provided in 15 units (16.9%), which means Initiatives at facilities are essential. We suggest evidence-based practical recommendations in Japan are necessary for neonates to minimize postoperative pain, enhance neonatal postoperative pain management knowledge, and provide consistent postoperative pain management appropriate to the neonates' condition by multidisciplinary collaboration among neonatal nurses, neonatologists, pediatric surgeons, and pediatric anesthesiologists.</p>","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":" ","pages":"771-778"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144020173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the article by Sato et al.","authors":"Triwiyanto Triwiyanto","doi":"10.1007/s00540-025-03501-1","DOIUrl":"10.1007/s00540-025-03501-1","url":null,"abstract":"","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":" ","pages":"823-824"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioimpedance analysis in clinical anesthesia: insights from two recent studies.","authors":"Shinju Obara","doi":"10.1007/s00540-025-03539-1","DOIUrl":"10.1007/s00540-025-03539-1","url":null,"abstract":"","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":" ","pages":"675-676"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phase angle as a prognostic factor for postoperative outcomes in major abdominal surgery: a single-center prospective observational study.","authors":"Yu Jeong Bang, Dawoon Jeong, Ji Hye Kwon, Yang Jin Park, Jeong-Jin Min","doi":"10.1007/s00540-025-03526-6","DOIUrl":"10.1007/s00540-025-03526-6","url":null,"abstract":"<p><strong>Purpose: </strong>Phase angle (PA), derived from bioelectrical impedance-analysis (BIA) has emerged as a reliable marker predicting clinical outcomes. This prospective observational study investigated the association between PA and a composite in-hospital outcome in major abdominal surgery.</p><p><strong>Methods: </strong>Each patient underwent BIA before surgery (PA_pre), immediately postoperatively (PA_post), and 1 day postoperatively (PA_POD1). Specific assessment for frailty and nutrition status was performed before surgery. Patient outcomes were assessed using a composite adverse outcome comprising death, myocardial infarction, revascularization, stroke, hemodynamic instability, acute kidney injury, pulmonary complications, delirium, ileus, and surgical complications during hospitalization. One-year complication, including all-cause mortality, myocardial infarction, stroke, surgical complications, and readmission after discharge within the year were also assessed.</p><p><strong>Results: </strong>A total of 122 adults who underwent major abdominal surgery were enrolled from July 2019 and April 2021. Twenty-three patients (53.5%) in the lower PA group (PA < 5) experienced in-hospital complications compared to 38 patients (34.2%) in the higher PA group (PA ≥ 5) (relative risk, 1.6; 95% confidence interval [CI], 1.0 to 2.4; p = 0.038). PA_pre was significantly associated with in-hospital complications (odds ratio, 0.491; 95% CI, 0.279 to 0.862; p < 0.001). Patients with lower PA_pre had a higher degree of frailty, and poor nutritional status. However, PA_pre was not significantly associated with 1-year composite complications.</p><p><strong>Conclusion: </strong>Low PA_pre was associated with adverse postoperative outcomes after major abdominal surgery. PA can be a reliable prognostic factor to predict in-hospital complications in patients undergoing major abdominal surgery, serving as an alternative surrogate to frailty indices and nutritional markers.</p><p><strong>Trial registration: </strong>Clinical Research Information Services of the Republic of Korea (CRIS identifier: KCT0004160).</p>","PeriodicalId":14997,"journal":{"name":"Journal of Anesthesia","volume":" ","pages":"750-759"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12464096/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}