Journal of Applied Biomaterials & Functional Materials最新文献

{"title":"<ArticleTitle xmlns:ns0=\"http://www.w3.org/1998/Math/MathML\">Irreversibility process analysis for <ns0:math><ns0:mrow><ns0:mi>S</ns0:mi><ns0:mi>i</ns0:mi><ns0:msub><ns0:mi>O</ns0:mi><ns0:mn>2</ns0:mn></ns0:msub><ns0:mo>-</ns0:mo><ns0:mi>M</ns0:mi><ns0:mi>o</ns0:mi><ns0:msub><ns0:mi>S</ns0:mi><ns0:mn>2</ns0:mn></ns0:msub></ns0:mrow></ns0:math>/water-based flow over a rotating and stretching cylinder.","authors":"Masood Khan,&nbsp;Mahnoor Sarfraz,&nbsp;Sabba Mehmood,&nbsp;Malik Zaka Ullah","doi":"10.1177/22808000221120329","DOIUrl":"https://doi.org/10.1177/22808000221120329","url":null,"abstract":"<p><p>Entropy is the measure of the amount of energy in any physical system that is not accessible for the useful work, which causes a decrease in a system's thermodynamic efficiency. The idea of entropy generation analysis plays a vital role in characterizing the evolution of thermal processes and minimizing the impending loss of available mechanical power in thermo-fluid systems from an analytical perspective. It has a wide range of applications in biological, information, and engineering systems, such as transportation, telecommunication, and rate processes. The analysis of the entropy generation of axisymmetric magnetohydrodynamic hybrid nanofluid <math><mrow><mrow><mo>(</mo><mrow><mi>S</mi><mi>i</mi><msub><mi>O</mi><mn>2</mn></msub><mo>-</mo><mi>M</mi><mi>o</mi><msub><mi>S</mi><mn>2</mn></msub></mrow><mo>)</mo></mrow></mrow></math>/water flow induced by rotating and stretching cylinder in the presence of heat radiation, ohmic heating, and the magnetic field is focus of this study. Thermal energy transport of hybrid nanofluids is performed by applying the Maxwell model. Heat transport is carried out by using convective boundary condition. The dimensionless ordinary differential equations are acquired by similarity transformations. The numerical solution for these differential equations is obtained by the <i>bvp4c</i> program in MATLAB. A comparison between nanofluid and hybrid nanofluid is made for flow field, temperature, and entropy generation. Comparison of nanofluid flow with hybrid nanofluid flow exhibits a higher rate of heat transmission, while entropy generation exhibits the opposite behavior. It is observed that the flow and heat distribution increase as the solid volume fraction's value grows. An increase in entropy is indicated by augmentation in the Brinkman number and temperature ratio parameter, but the Bejan number shows a declining trend. Furthermore, outcomes of the Nusselt number for hybrid nanofluid and nanofluid are calculated for various parameters. It is noticed that the Nusselt number is reduced for enlarging the magnetic field and Eckert number. The axial and azimuthal wall stress parameters are declined by augmenting the Reynolds number.</p>","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":" ","pages":"22808000221120329"},"PeriodicalIF":2.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33445317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A low-shrinkage, hydrophobic, degradation-resistant, antimicrobial dental composite using a fluorinated acrylate and an oxirane.","authors":"Clara Bergeron,&nbsp;Cori Ballard,&nbsp;Yiming Li,&nbsp;Wu Zhang,&nbsp;Zhe Zhong,&nbsp;Kyumin Whang","doi":"10.1177/22808000221087337","DOIUrl":"https://doi.org/10.1177/22808000221087337","url":null,"abstract":"<p><strong>Objective: </strong>To develop a low shrinkage, hydrophobic, degradation-resistant, antimicrobial dental composite using a fluorinated acrylate, and a difunctional oxirane.</p><p><strong>Methods: </strong>The effects of a fluorinated acrylate (2-(perfluorooctyl)ethyl acrylate; PFOEA), a difunctional oxirane (EPALLOY™ 5001; EP5001), and a three-component initiator system (camphorquinone/ethyl 4-dimethylaminobenzoate/4-Isopropyl-4'-methyldiphenyl iodonium Tetrakis (pentafluorophenyl) borate; CQ/EDMAB/Borate) on bisphenol A glycidyl dimethacrylate: triethylene glycol dimethacrylate (BisGMA:TEGDMA) composite surface hardness, degree of monomer-to-polymer conversion, hydrophobicity, translucency, mechanical properties, polymerization shrinkage and shrinkage stress, degradation, water imbibition, and antimicrobial properties were determined.</p><p><strong>Results: </strong>Overall the experimental composites had comparable mechanical properties and lower volumetric polymerization shrinkage and shrinkage stress as compared to BisGMA:TEGDMA controls. Addition of PFOEA increased composite hydrophobicity, but it decreased degree of cure, ultimate transverse strength, and translucency. It also decreased polymerization shrinkage and shrinkage stress. The use of the CQ/EDMAB/Borate initiator system was beneficial for the cure and mechanical properties of the 30% w/w PFOEA group. However, it decreased the hydrophobicity and translucency of those composites. The addition of EP5001, at the low concentration used in this work, did not contribute to reduced polymerization volumetric shrinkage or antimicrobial properties, but it did reduce shrinkage stress.</p><p><strong>Conclusions: </strong>A mechanically viable hydrophobic composite system with reduced polymerization shrinkage and shrinkage stress has been developed by adding PFOEA and EP5001. However, the addition of EP5001 did not render the composite antimicrobial due to the low concentration used. Further research is needed to determine the lowest concentration at which EP5001 provides antimicrobial activity. The composites developed here have the potential to improve longevity of traditional BisGMA:TEGDMA composite systems.</p>","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":" ","pages":"22808000221087337"},"PeriodicalIF":2.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40313409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fabrication method for a magnetically induced highly oriented nanohydroxyapatite/collagen composite.","authors":"Huang Shuai,&nbsp;Zhou Xiaoni,&nbsp;Liu Yan,&nbsp;Liu Yanle,&nbsp;Duan Yan,&nbsp;Meng Lu,&nbsp;Song Yingliang,&nbsp;Ma Wei","doi":"10.1177/22808000221105727","DOIUrl":"https://doi.org/10.1177/22808000221105727","url":null,"abstract":"<p><p>Both collagen fibres and nanohydroxyapatite crystals have anisotropic magnetisation, which allows them to be oriented by a high magnetic field. Highly oriented nanohydroxyapatite/collagen composites were prepared using a high magnetic field combined with in situ synthesis. These highly oriented composites were investigated and compared with conventional composites. The results showed that the collagen fibres in the magnetically induced highly oriented nanohydroxyapatite/collagen composites had a preferred orientation and smaller molecular spacing, while the nanohydroxyapatite crystals were tightly adhered along the collagen fibre surface. The magnetically induced composites exhibited superior resistance to swelling and degradation along with high compressive strength. This artificial composite, with a structure and composition similar to natural bone, represents a new idea for improving materials for vertical or horizontal bone augmentation.</p>","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":" ","pages":"22808000221105727"},"PeriodicalIF":2.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40560048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Finite element analysis and energy recovery calculation of carbon fiber composite based on ANSYS software.","authors":"Jianxiao Zheng,&nbsp;Zhishan Duan,&nbsp;Liming Zhou","doi":"10.1177/22808000221140059","DOIUrl":"https://doi.org/10.1177/22808000221140059","url":null,"abstract":"<p><strong>Purpose: </strong>To study the response under impact load of carbon fiber reinforced composite materials that have excellent mechanical properties.</p><p><strong>Design/methodology/approach: </strong>Finite element analysis of unidirectional plates was conducted under unsymmetrical impact load based on drop weight impact test. At the macroscopic scale, a finite element model was built on ANSYS/LS-DYNA, which took the impact response of carbon fiber unidirectional plates as unknown quantity. The model considered the macroscopic response of carbon fiber unidirectional plates under different initial conditions, from the aspects of stress, strain, energy change and deformation degree of unidirectional plates. Finally, a mathematical model of energy recovery of carbon fiber composite materials under partial impact load was established, and the energy recovery amount under different fiber orientations was calculated on MATLAB.</p><p><strong>Findings: </strong>The impact energy absorbed by the unidirectional plate is the largest when the fiber orientation is 30°. To improve the impact resistance of unidirectional plates under unsymmetrical impact load, laying schemes should be avoided at fiber orientations of 0°, 15° and 60°, and be recommended at 30°, 45°, and 75°. For impact velocity, 4.71 and 7.54 m/s should be avoided, while 2 m/s is recommended. For the impact weight, 50 and 250 kg weights should be avoided, and 150 and 200 kg weights are recommended.</p><p><strong>Originality/value: </strong>This model not only provides reference for similar impact resistance research, but also predicts the impact response of unidirectional plates under different initial loads in the future. It can also provide reference for the structure using carbon fiber composite materials to achieve lightweight.</p>","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":" ","pages":"22808000221140059"},"PeriodicalIF":2.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35252497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanofluids modeling and energy transformation under the influence of mixed convection: Role of aluminum and γ-aluminum nanoparticles.","authors":"Haneen Hamam,&nbsp;Awatif Alhowaity,&nbsp;Umar Khan,&nbsp;Adnan,&nbsp;Basharat Ullah,&nbsp;Wahid Khan","doi":"10.1177/22808000221114715","DOIUrl":"https://doi.org/10.1177/22808000221114715","url":null,"abstract":"<p><p>The analysis of nanofluids under various physical scenarios convinced the researchers and scientists because of their broad range of applications in potential area of the current time like chemical engineering, biomedical engineering and applied thermal engineering etc. To give the final shape of many industrial and engineering processes, enhanced heat transfer desired, therefore, the study of Al₂O₃-H₂O, γAl₂O₃-H₂O, Al₂O₃-C₂H₆O₂, and γAl₂O₃- C₂H₆O₂ nanofluids is reported. The model successfully achieved after mathematical operations and by appealing similarity transforms. To examine the behavior of heat transfer, numerical tools utilized and performed the results. It is observed that enhanced heat transfer in Al₂O₃-H₂O, γAl₂O₃-H₂O, Al₂O₃-C₂H₆O₂, and γAl₂O₃-C₂H₆O₂ could be attained by setting nanoparticles concentration up to 20%. For Al₂O₃-H₂O, γAl₂O₃-H₂O, optimum heat transfer trends noticed due to their prominent thermophysical values. Also, fewer effects of combined convection on <math><mrow><mi>θ</mi><mo>(</mo><mi>η</mi><mo>)</mo></mrow></math> examined.</p>","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":" ","pages":"22808000221114715"},"PeriodicalIF":2.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40572484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electroplating of HAp-brushite coating on metallic bioimplants with advanced hemocompatibility and osteocompatibility properties.","authors":"Yanhong Wang,&nbsp;Bing Wu,&nbsp;Songtao Ai,&nbsp;Daqian Wan","doi":"10.1177/22808000221103970","DOIUrl":"https://doi.org/10.1177/22808000221103970","url":null,"abstract":"<p><p>In cases of severe bone tissue injuries, the use of metallic bioimplants is quite widespread due to their high strength, high fracture toughness, hardness, and corrosion resistance. However, they lack adequate biocompatibility and show poor metal-tissue integration during the post-operative phase. To mitigate this drawback, it is beneficial to add a biocompatible polymer layer to ensure a quick growth of cell or tissue over the surface of metallic bioimplant material. Furthermore, this additional layer should possess good adherence with the underlying material and also accompany a rapid bonding between the tissue and the implant material, in order to reduce the recovery time for the patient. Therefore, in this work, we report a novel green electroplating route for growing porous hydroxyapatite-brushite coatings on a stainless steel surface. The malic acid used for the production of hydroxyapatite-brushite coatings has been obtained from an extract of locally available apple fruit (<i>Malus domestica</i>). We demonstrate the effect of electroplating parameters on the structural morphology of the electroplated composite layer via XRD, SEM with EDS, and FTIR characterization techniques and report an optimized set of electroplating parameters that will yield the best composite coating in terms of thickness, adherence to substrate and speed. The hemocompatibility and osteocompatibility studies on the electroplated composites coating show this technology's effectiveness and potential applicability in biomedical applications. Compared to other routes reported in the literature, this electroplating route is quicker and yields better composite coatings with faster bone tissue growth potential.</p>","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":" ","pages":"22808000221103970"},"PeriodicalIF":2.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40615032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of firing temperature and duration on the hardness of dental zirconia for optimum selection of sintering conditions.","authors":"Omar Al-Surkhi,&nbsp;Zeina Hamad","doi":"10.1177/22808000221114218","DOIUrl":"https://doi.org/10.1177/22808000221114218","url":null,"abstract":"<p><strong>Objective: </strong>In order to optimize the properties of dental zirconia, the sintering process involves firing zirconia to elevated temperatures for an extended time that can take several hours. The aim of this study is to investigate the effect of firing temperature and firing duration on the hardness of dental zirconia to indicate the optimum sintering conditions.</p><p><strong>Methods: </strong>Thirty-six zirconia specimens in shape of bars were randomly assigned to nine groups. The zirconia specimen groups were sintered using a sintering furnace with different firing temperatures (900°C, 1200°C, and 1800°C) and firing durations (6, 9, and 12 h). A total of 108 hardness measurements were conducted for all specimens (12 hardness readings per group). For each of the specimen groups, micro Vickers hardness test was performed using a load of 1 Kgf (9.807 N) and the Vickers hardness number was computed. Statistical analysis using Kruskal-Wallis test was conducted to examine the significant differences on Vickers hardness number HV among the specimen groups according to the firing parameters with 0.005 <i>p</i>-value used as an indicator.</p><p><strong>Results: </strong>Results suggest that there is an association between the increase in the hardness number and the increase in firing duration at a given firing temperature. The results also indicate that there is an association between the increase in the hardness number and increase in firing temperature at a given firing duration.</p><p><strong>Conclusions: </strong>The greatest rate of hardness increase with time is associated with groups of firing temperature 1200°C. The highest rate of hardness increase with temperature happened during the first 6 h of sintering process. On the other hand, there is no significant increase in the hardness number when increasing the firing temperature beyond 1200°C.</p>","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":" ","pages":"22808000221114218"},"PeriodicalIF":2.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40537111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thermal transport of biological base fluid with copper and iron oxide nanoparticles in wavy channel.","authors":"Kamel Guedri,&nbsp;Aamar Abbasi,&nbsp;Kamel Al-Khaled,&nbsp;Waseh Farooq,&nbsp;Sami Ullah Khan,&nbsp;Muhammad Ijaz Khan,&nbsp;Ahmed M Galal","doi":"10.1177/22808000221125870","DOIUrl":"https://doi.org/10.1177/22808000221125870","url":null,"abstract":"<p><p>The nanoparticles are frequently used in biomedical science for the treatment of diseases like cancer and these nanoparticles are injected in blood which is transported in the cardiovascular system on the principle of peristalsis. This study elaborates the effects of Lorentz force and joule heating on the peristaltic flow of copper and iron oxide suspended blood based nanofluid in a complex wavy non-uniform curved channel. The Brinkman model is utilized for the temperature dependent viscosity and thermal conductivity. The problem is formulated using the fundamental laws in terms of coupled partial differential equations which are simplified using the creeping flow phenomenon. The graphical results for velocity, temperature, streamlines, and axial pressure are simulated numerically. The concluded observations deduce that the solid volume fraction of nanoparticles reduces the velocity and enhance the pressure gradient and accumulation of trapping bolus in the upper half of the curved channel is noticed for temperature dependent viscosity.</p>","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":" ","pages":"22808000221125870"},"PeriodicalIF":2.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40463799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the use of a Ruthenium complex incorporated into a methacrylate-based dental material for antimicrobial photodynamic therapy.","authors":"Adriana Pigozzo Manso,&nbsp;Maria Luísa Leite,&nbsp;Patricia Comeau,&nbsp;Claudia Dietrich,&nbsp;Sahand Ghaffari,&nbsp;Dirk Lange,&nbsp;Neil Branda","doi":"10.1177/22808000221112989","DOIUrl":"https://doi.org/10.1177/22808000221112989","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the effects of a blue light photosensitizer (PS), Ruthenium II complex (Ru), on the chemical, physical, mechanical, and antimicrobial properties of experimental dental resin blends.</p><p><strong>Methods: </strong>The experimental resin (BisEMA, TEEGDMA, HPMA, ethanol, and photoinitiator) was loaded with Ru at 0.00%, 0.07%, 0.14%, 0.28%, 0.56%, 1.12%, 1.2%, 1.5%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, or 10% w/w. Samples were evaluated for the degree of conversion (DC) after 30 and 60 s curing-time (<i>n</i> = 6). Selected formulations (0.00%, 0.28%, 0.56%, 1.12%) were further tested for shear bond strength (SBS) (<i>n</i> = 15); flexural strength (FS) (<i>n</i> = 12); and antimicrobial properties (CFUs), in dark and light conditions. These latter tests were performed on specimens stored for 24-h or 2-month in 37°C water. Water sorption (WS) and solubility (SL) tests were also performed (<i>n</i> = 12). Data were analyzed either by a one- or two-factor general linear model (α = 0.05).</p><p><strong>Results: </strong>Overall, Ru concentration above 1.2% resulted in reduced DC. In SBS results, only the 1.12%Ru resin blend samples had statistically lower values compared to the 0.00%Ru resin blend at 24-h storage (<i>p</i> = 0.004). In addition, no differences in SBS were detected among the experimental groups after 2-month storage in water. Meanwhile, FS increased for all experimental groups under similar aging conditions (<i>p</i> < 0.001). Antimicrobial properties were improved upon inclusion of Ru and application of light (<i>p</i> < 0.001 for both) at 24-h and 2-month storage. Lastly, no detectable changes in WS or SL were observed for the Ru-added resins compared to the 0.00%Ru resin blend. However, the 0.28% Ru blend presented significantly higher WS compared to the 0.56% Ru blend (<i>p</i> = 0.007).</p><p><strong>Conclusions: </strong>Stable SBS, improved FS, and sustained antimicrobial properties after aging gives significant credence to our approach of adding the Ruthenium II complex into dental adhesive resin blends intended for an aPDT approach.</p>","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":" ","pages":"22808000221112989"},"PeriodicalIF":2.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40607424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibacterial multicomponent electrospun nanofibrous mat through the synergistic effect of biopolymers.","authors":"Md Abdus Shahid,&nbsp;Md Mehedi Hasan,&nbsp;Md Rubel Alam,&nbsp;Md Mohebullah,&nbsp;Mohammad Asaduzzaman Chowdhury","doi":"10.1177/22808000221136061","DOIUrl":"https://doi.org/10.1177/22808000221136061","url":null,"abstract":"<p><p>The endeavor was to adopt a facile bi-layered approach to fabricate a novel PVA-chitosan-collagen-licorice nanofibrous mat (PCCLNM) with maintaining the spinning parameters and conditions to assess the synergistic antibacterial action of two biopolymers and having properties for repairing tissues. Bonding behavior, morphological orientation, antibacterial activity, and moisture management features of the electrospun nanofibrous mat were investigated using various characterization techniques. The FTIR analysis of the manufactured nanofibrous mat revealed characteristic peaks of licorice, chitosan, collagen, and PVA polymer, confirming the presence of all polymers in the sample. Additionally, a scanning electron microscopy (SEM) image attributes the development of nanofibers with an average diameter for top and bottom sides were 219 and 188 nm respectively. Furthermore, moisture management tests (MMT) confirm PCCLNM's slow absorption and drying capabilities. Apart from that, a disk diffusion method was used to investigate antibacterial activity against the bacteria <i>Staphylococcus aureus (S. aureus)</i>, which revealed a strong presence of antibacterial activity with a 20 mm zone of inhibition due to the chemical constituents of licorice and chitosan compound. The developed bio-nanocomposite could have a potential application as wound healing material.</p>","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":" ","pages":"22808000221136061"},"PeriodicalIF":2.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40453643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}