Journal of Analytical Science and Technology最新文献_第3页

Development of non-destructive isotope measurement of the natural galena (PbS) using negative muon beams 利用负μ介子束开发天然方铅矿（PbS）无损同位素测量技术

IF 2.4 4区化学

Journal of Analytical Science and Technology Pub Date : 2024-05-07 DOI: 10.1186/s40543-024-00440-6

K. Terada, K. Ninomiya, A. Sato, D. Tomono, Y. Kawashima, M. Inagaki, A. Nambu, T. Kudo, T. Osawa, M. K. Kubo

引用次数: 0

Fast, accessible and reliable method for elemental analysis of metals in solution by ED-XRF spectroscopy 利用电离辐射 XRF 光谱快速、便捷、可靠地分析溶液中金属元素的方法

IF 2.4 4区化学

Journal of Analytical Science and Technology Pub Date : 2024-05-07 DOI: 10.1186/s40543-024-00442-4

Filipe M. J. Figueiredo, José M. Carretas, João P. Leal, José M. Sardinha

{"title":"Fast, accessible and reliable method for elemental analysis of metals in solution by ED-XRF spectroscopy","authors":"Filipe M. J. Figueiredo, José M. Carretas, João P. Leal, José M. Sardinha","doi":"10.1186/s40543-024-00442-4","DOIUrl":"https://doi.org/10.1186/s40543-024-00442-4","url":null,"abstract":"The measurement of metals in solution is usually performed using inductive coupled plasma hyphenated techniques or atomic absorption. Although very sensitive and accurate, these analytical techniques are quite expensive and do not allow field measurements. The present work takes advantage of energy-dispersive X-ray fluorescence (ED-XRF) ease-of-use features to determine the concentration of rare earth elements (Y, Pr, Nd, Eu) and others (S, Fe, Ni, Cu, Zn) in aqueous solutions, after appropriate sample treatment. The approach turned out to be a reliable and very convenient procedure for field analysis. The simplicity, speed and reliability of the methodology used combined with the possibility of simultaneous analysis and low cost of the method can be advantageous in industrial context. The approach relies on the suspension of the target solutions in a cellulose matrix that is further converted into a pellet for direct analysis. Calibration curves obtained by regression analysis at 5% significance are shown for a variety of elements (S, Fe, Ni, Cu, Zn, Y, Pr, Nd, Eu) with correlation coefficients between 0.9555 and 0.9980. Higher coefficients of variance were obtained for the calibration of S and Pr due to low sensitivity and the overlapping with the L lines of Nd, respectively. The performed calibrations were not affected by the presence of other analytes in the matrix. Results obtained showed that it is possible to use the proposed methodology to accurately quantify d and f block metals in aqueous solutions by ED-XRF after sequestering the chemical content into a cellulose powder matrix and further processing into a pellet. ","PeriodicalId":14967,"journal":{"name":"Journal of Analytical Science and Technology","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140889618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SIMS study of fine-scale distribution of U, Th and Pb in meteorites 陨石中铀、钍和铅的细粒度分布的 SIMS 研究

IF 2.4 4区化学

Journal of Analytical Science and Technology Pub Date : 2024-05-01 DOI: 10.1186/s40543-024-00439-z

Keewook Yi, Yuri Amelin

{"title":"SIMS study of fine-scale distribution of U, Th and Pb in meteorites","authors":"Keewook Yi, Yuri Amelin","doi":"10.1186/s40543-024-00439-z","DOIUrl":"https://doi.org/10.1186/s40543-024-00439-z","url":null,"abstract":"We report developing a procedure for measuring concentrations of U, Th and Pb (including all natural Pb isotopes) to establish the distribution of these elements in meteorite minerals and correctly interpret Pb-isotopic ages of meteorites. The concentrations were measured on KBSI SHRIMP IIe by peak jumping using a discrete-dynode secondary electron multiplier. The concentrations were calculated relative to BCR-2G glass and monitored by analysis of the NIST glasses SRM-615 and SRM-617 as secondary reference materials. The detection limits using the spot sizes of ca. 180 μm2, primary O2− beam current of 10.6 nA, and with amplifier dark noise of 0.015 counts per second are ~ 0.2 parts per billion (ppb) for U (500 s integration), ~ 0.6 ppb for Pb (100 s integration for each of the major isotopes), and ~ 1.2 ppb for Th (100 s integration). Analyses of the NIST glasses confirm that the measured concentrations of U and Th are consistent with their certified values, while the Pb concentrations are about four times too low, most likely due to the compositional mismatch between the primary and secondary reference materials. The achieved level of sensitivity and concentration precision (~ 20–30%) is adequate for measuring U, Th and Pb distributions in both rock-forming and accessory minerals in chondrites, achondrites, and their components.","PeriodicalId":14967,"journal":{"name":"Journal of Analytical Science and Technology","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140832088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aptamer-based protein molecule detection via cyclic reverse transcription coupling with self-priming hairpin-triggered CRISPR-Cas12a system 通过自吸发夹触发的 CRISPR-Cas12a 系统与循环反转录耦合进行基于色聚体的蛋白质分子检测

IF 2.4 4区化学

Journal of Analytical Science and Technology Pub Date : 2024-04-30 DOI: 10.1186/s40543-024-00441-5

Jie Gao, Xiaoqing Yang

{"title":"Aptamer-based protein molecule detection via cyclic reverse transcription coupling with self-priming hairpin-triggered CRISPR-Cas12a system","authors":"Jie Gao, Xiaoqing Yang","doi":"10.1186/s40543-024-00441-5","DOIUrl":"https://doi.org/10.1186/s40543-024-00441-5","url":null,"abstract":"Protein biomarkers (e.g. thrombin) are of great significance for the biological process of the organism, and its aberrant expression is closely associated with the development of diseases. With thrombin, a serine protease that plays a crucial role in maintaining homeostasis and promoting blood clotting, as detection target, this study introduces a novel approach for sensitive and accurate measurement of protein biomarker expression by utilization of cyclic reverse transcription (CRT) in combination with the self-priming hairpin-triggered CRISPR-Cas12a system. In this method, an elegantly designed sensing probe is utilized to specifically bind with the thrombin protein and convert the protein signals to nucleic acids signals, following by the CRT and CRISPR-Cas12a system-based signal amplification strategy. Taking the merit of the two-stage amplification, this assay has the capability to detect thrombin at the fM level. In addition, due to the aptamer sequence’s strong selectivity to thrombin protein and the dual-check process in the signal amplification process (first in the CRT and second in the CRISPR system), the proposed test demonstrates exceptional specificity in detecting thrombin. By re-designing the sensing probe, the established method could be extended to various protein biomarker detection. Ultimately, this assay has successfully enabled the accurate evaluation of biomarker levels in constructed clinical samples, showing significant potential for application in the realm of clinical molecular diagnosis.","PeriodicalId":14967,"journal":{"name":"Journal of Analytical Science and Technology","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140831909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of the antibacterial efficacy of silver nanoparticles-based Artemisia annua against methicillin-resistant Staphylococcus aureus-infected lung tissues in albino rats 基于银纳米颗粒的青蒿对白化大鼠肺组织耐甲氧西林金黄色葡萄球菌感染的抗菌效果评估

IF 2.4 4区化学

Journal of Analytical Science and Technology Pub Date : 2024-04-25 DOI: 10.1186/s40543-024-00436-2

M. T. Shaaban, M. Abdel-Hamid, S. Orabi, R. Korany, R. H. Elbawab

引用次数: 0

Advances in mass spectrometry-based approaches for characterizing monoclonal antibodies: resolving structural complexity and analytical challenges 基于质谱的单克隆抗体表征方法的进展：解决结构复杂性和分析难题

IF 2.4 4区化学

Journal of Analytical Science and Technology Pub Date : 2024-04-23 DOI: 10.1186/s40543-024-00437-1

Abhik Mojumdar, Hee-Jin Yoo, Duck-Hyun Kim, Jiwon Park, Su-Jin Park, Eunji Jeon, Sunhee Choi, Jung Hoon Choi, Moonhee Park, Geul Bang, Kun Cho

引用次数: 0

Sample size and the limits to precision in Pb-isotopic dating by ID-TIMS 利用 ID-TIMS 进行铅同位素年代测定时的样本量和精确度限制

IF 2.4 4区化学

Journal of Analytical Science and Technology Pub Date : 2024-04-23 DOI: 10.1186/s40543-024-00435-3

Yuri Amelin

引用次数: 1

Hf-W dating of zircon in mesosiderite with high-pressure sintered standard 用高压烧结标准对介闪石中的锆石进行Hf-W测年

IF 2.4 4区化学

Journal of Analytical Science and Technology Pub Date : 2024-04-23 DOI: 10.1186/s40543-024-00438-0

Yuji Sano, Yuta Koyama, N. Takahata, Takuya Matsuzaki, M. Koike, M. Haba, Shuhei Sakata, H. Kuwahara, Tetsuo Irifune

引用次数: 1

Performance assessment of activated carbon thermally modified with iron in the desulfurization of biogas in a static batch system supported by headspace gas chromatography 铁热改性活性炭在顶空气相色谱法支持的静态批处理系统中用于沼气脱硫的性能评估

IF 2.4 4区化学

Journal of Analytical Science and Technology Pub Date : 2024-04-16 DOI: 10.1186/s40543-024-00432-6

Mayerlin Edith Acuña Montaño, Luciane Effting, Carmen Luisa Barbosa Guedes, Gregorio Guadalupe Carbajal Arizaga, Renata Mello Giona, Patricia Hissae Yassue Cordeiro, César Ricardo Teixeira Tarley, Alesandro Bail

{"title":"Performance assessment of activated carbon thermally modified with iron in the desulfurization of biogas in a static batch system supported by headspace gas chromatography","authors":"Mayerlin Edith Acuña Montaño, Luciane Effting, Carmen Luisa Barbosa Guedes, Gregorio Guadalupe Carbajal Arizaga, Renata Mello Giona, Patricia Hissae Yassue Cordeiro, César Ricardo Teixeira Tarley, Alesandro Bail","doi":"10.1186/s40543-024-00432-6","DOIUrl":"https://doi.org/10.1186/s40543-024-00432-6","url":null,"abstract":"A static batch arrangement composed of anti-leak vials coupled to gas chromatography is proposed as a complementary system for performance assessment of biogas desulfurization by adsorption. For testing, a modified commercial activated carbon produced by controlled thermal treatment in the presence of iron(III) species improved biogas desulfurization. The adsorbents showed a superior hydrogen sulfide removal compared to ordinary one. Pseudo-first-order, pseudo-second-order, and Bangham’s kinetic models were used to fit experimental data. All studied samples followed pseudo-first-order model, indicating the predominance of physisorption, and Bangham’s model, confirming that the micropores structure played an important role for gases diffusion and adsorbent capacity. Additionally, the materials were characterized by N2 adsorption–desorption, X-ray diffraction, infrared spectroscopy, scanning electron microscopy and energy-dispersive spectroscopy. The thermal treatment associated with iron impregnation caused significant modifications in the surface of the materials, and the iron species showed two main benefits: an expressive increase in the specific area and the formation of specific adsorption sites for hydrogen sulfide removal. The results reinforce the advantages of iron-modified adsorbents in relation to their non-modified counterparts. The analytical methodology based on the confinement of multiple gases contributes to improving the understanding of the hydrogen sulfide adsorption process using pressure swing adsorption technology. ","PeriodicalId":14967,"journal":{"name":"Journal of Analytical Science and Technology","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140589917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Direct and accurate miRNA detection based on CRISPR/Cas13a-triggered exonuclease-iii-assisted colorimetric assay 基于 CRISPR/Cas13a 触发的外切酶-iii 辅助比色法的直接准确 miRNA 检测

IF 2.4 4区化学

Journal of Analytical Science and Technology Pub Date : 2024-04-16 DOI: 10.1186/s40543-024-00434-4

Yunxiao Li, Qiuxia Wang, Yali Wang

{"title":"Direct and accurate miRNA detection based on CRISPR/Cas13a-triggered exonuclease-iii-assisted colorimetric assay","authors":"Yunxiao Li, Qiuxia Wang, Yali Wang","doi":"10.1186/s40543-024-00434-4","DOIUrl":"https://doi.org/10.1186/s40543-024-00434-4","url":null,"abstract":"The abnormally expressed microRNAs (miRNAs) serve as crucial indicators for disease diagnosis and are strongly associated with the progression of various diseases. The quantification of miRNAs is highly significant for the clinical diagnosis and treatment of various types of cancers. This study utilizes the CRISPR/Cas13a system, which combines CRISPR RNA (crRNA) and CRISPR-associated Cas13a, to recognize the miRNA directly and specifically, thus activating the trans-cleavage activity of Cas13a. By integrating the CRISPR-Cas13a system with an exonuclease-iii (Exo-iii)-assisted chain cleavage of silver ions (Ag+)-aptamer and an Ag+ -based color reaction, a method for the detection of miRNA that is specific and sensitive is developed. This approach demonstrated exceptional sensitivity in detecting miRNA, with a low detection limit of 5.12 fM. Moreover, the suggested method was effectively utilized to precisely measure the amount of miRNA in intricate biological samples, demonstrating its practical applicability. Furthermore, due to its elevated sensitivity and simple probe design and fluorophore labeling, the suggested colorimetric technique holds great potential for use in clinical diagnostics.","PeriodicalId":14967,"journal":{"name":"Journal of Analytical Science and Technology","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140589464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0