Jornal Brasileiro De Pneumologia最新文献_第4页

Impact of telehealth during the COVID-19 pandemic on clinical and nutritional conditions of adolescents with cystic fibrosis. COVID-19 大流行期间远程保健对囊性纤维化青少年临床和营养状况的影响。

IF 2.7 4区医学

Jornal Brasileiro De Pneumologia Pub Date : 2024-05-27 DOI: 10.36416/1806-3756/e20230397

Lavínia Mayara da Silva Reis, Aline Antunes de Cerqueira Pinheiro, Maurício Antônio da Silva Júnior, Christine Pereira Gonçalves, Nelbe Nesi Santana

引用次数: 0

A critical analysis of the decreasing trends in tuberculosis cure indicators in Brazil, 2001-2022. 对 2001-2022 年巴西结核病治愈指标下降趋势的批判性分析。

IF 2.7 4区医学

Jornal Brasileiro De Pneumologia Pub Date : 2024-05-27 eCollection Date: 2024-01-01 DOI: 10.36416/1806-3756/e20240018

Gabriel Pavinati, Lucas Vinícius de Lima, Pedro Henrique Paiva Bernardo, Jhenicy Rubira Dias, Bárbara Reis-Santos, Gabriela Tavares Magnabosco

{"title":"A critical analysis of the decreasing trends in tuberculosis cure indicators in Brazil, 2001-2022.","authors":"Gabriel Pavinati, Lucas Vinícius de Lima, Pedro Henrique Paiva Bernardo, Jhenicy Rubira Dias, Bárbara Reis-Santos, Gabriela Tavares Magnabosco","doi":"10.36416/1806-3756/e20240018","DOIUrl":"10.36416/1806-3756/e20240018","url":null,"abstract":"Objective: To analyze the temporal trend of tuberculosis cure indicators in Brazil.Methods: An ecological time-series study using administrative data of reported cases of the disease nationwide between 2001 and 2022. We estimated cure indicators for each federative unit (FU) considering individuals with pulmonary tuberculosis, tuberculosis-HIV coinfection, and those in tuberculosis retreatment. We used regression models using joinpoint regression for trend analysis, reporting the annual percentage change and the average annual percentage change.Results: For the three groups analyzed, we observed heterogeneity in the annual percentage change in the Brazilian FUs, with a predominance of significantly decreasing trends in the cure indicator in most FUs, especially at the end of the time series. When considering national indicators, an average annual percentage change of -0.97% (95% CI: -1.23 to -0.74) was identified for the cure of people with pulmonary tuberculosis, of -1.11% (95% CI: -1.42 to -0.85) for the cure of people with tuberculosis-HIV coinfection, and of -1.44% (95% CI: -1.62 to -1.31) for the cure of people in tuberculosis retreatment.Conclusions: The decreasing trends of cure indicators in Brazil are concerning and underscore a warning to public authorities, as it points to the possible occurrence of other treatment outcomes, such as treatment discontinuity and death. This finding contradicts current public health care policies and requires urgent strategies aiming to promote follow-up of patients during tuberculosis treatment in Brazil.","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"50 2","pages":"e20240018"},"PeriodicalIF":2.7,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11185134/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141160783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenges in the treatment of cystic fibrosis in the era of CFTR modulatorsAuthors' replyUse of elexacaftor+tezacaftor+ivacaftor in individuals with cystic fibrosis and at least one F508del allele a systematic review and meta-analysisDiscontinuation versus continuation of hypertonic saline or dornase alfa in modulator treated people with cystic fibrosis (SIMPLIFY) results from two parallel, multicentre, open-label, randomised, controlled, non-inferiority trialsAssessing Safety of Discontinuing Hypertonic Saline in Those with Lower Forced Expiratory Volume in 1 Second after Elexacaftor/Tezacaftor/Ivacaftor. CFTR调节剂时代囊性纤维化治疗面临的挑战作者回复在囊性纤维化且至少有一个F508del等位基因的患者中使用eexacaftor+tezacaftor+ivacaftor的系统综述和荟萃分析在接受调节剂治疗的囊性纤维化患者中停用与继续使用高渗盐水或dornase alfa（SIMPLIFY）两项平行、多中心、开放标签、随机对照、非劣效性试验的结果评估停用高渗盐水对用力呼气容积降低者的安全性多中心、开放标签、随机对照、非劣效试验评估停用高渗盐水对 Elexacaftor/Tezacaftor/Ivacaftor 治疗后 1 秒内用力呼气容积降低者的安全性。

IF 2.9 4区医学

Jornal Brasileiro De Pneumologia Pub Date : 2024-05-27 DOI: 10.36416/1806-3756/e20240107

Caroline Jacoby Schmidt, Laura Silveira de Moura, Paulo de Tarso Roth Dalcin, Bruna Ziegler

引用次数: 0

Feasibility of EBUS-TBNA for the molecular characterization of non-small cell lung cancer. EBUS-TBNA 用于非小细胞肺癌分子特征描述的可行性。

IF 2.7 4区医学

Jornal Brasileiro De Pneumologia Pub Date : 2024-05-27 DOI: 10.36416/1806-3756/e20230193

Luis Vaz Rodrigues, Marta Viegas, Rosa Cordovilla, Luis Taborda-Barata, Vitor Sousa

引用次数: 0

Tracheobronchial amyloidosis and multiple myeloma. 气管支气管淀粉样变性和多发性骨髓瘤。

IF 2.9 4区医学

Jornal Brasileiro De Pneumologia Pub Date : 2024-05-27 DOI: 10.36416/1806-3756/e20240080

Luciana Volpon Soares Souza, Arthur Soares Souza, Edson Marchiori

引用次数: 0

Microbial variations in sputum cultures among hospitalized patients with community-acquired pneumonia: differences in sputum microbiota between asthma and COPD patients. 社区获得性肺炎住院患者痰培养物中的微生物变异：哮喘和慢性阻塞性肺病患者痰微生物群的差异。

IF 2.7 4区医学

Jornal Brasileiro De Pneumologia Pub Date : 2024-05-27 eCollection Date: 2024-01-01 DOI: 10.36416/1806-3756/e20230329

Fatih Uzer, Burcu Karaboğa, A Gamze Çalış, Nermin Kaplan, Rojan Barış Gedik, Ahmet Alper Durmuş, Umut Barış Inanc, Metin Akgün

{"title":"Microbial variations in sputum cultures among hospitalized patients with community-acquired pneumonia: differences in sputum microbiota between asthma and COPD patients.","authors":"Fatih Uzer, Burcu Karaboğa, A Gamze Çalış, Nermin Kaplan, Rojan Barış Gedik, Ahmet Alper Durmuş, Umut Barış Inanc, Metin Akgün","doi":"10.36416/1806-3756/e20230329","DOIUrl":"10.36416/1806-3756/e20230329","url":null,"abstract":"Objective: To assess differences in the sputum microbiota of community-acquired pneumonia (CAP) patients with either COPD or asthma, specifically focusing on a patient population in Turkey.Methods: This retrospective study included hospitalized patients > 18 years of age with a diagnosis of pneumonia between January of 2021 and January of 2023. Participants were recruited from two hospitals, and three patient groups were considered: CAP patients with asthma, CAP patients with COPD, and CAP patients without COPD or asthma.Results: A total of 246 patients with CAP were included in the study, 184 (74.8%) and 62 (25.2%) being males and females, with a mean age of 66 ± 14 years. Among the participants, 52.9% had COPD, 14.2% had asthma, and 32.9% had CAP but no COPD or asthma. Upon analysis of sputum cultures, positive sputum culture growth was observed in 52.9% of patients. The most commonly isolated microorganisms were Pseudomonas aeruginosa (n = 40), Acinetobacter baumannii (n = 20), Klebsiella pneumoniae (n = 16), and Moraxella catarrhalis (n = 8). CAP patients with COPD were more likely to have a positive sputum culture (p = 0.038), a history of antibiotic use within the past three months (p = 0.03), utilization of long-term home oxygen therapy (p < 0.001), and use of noninvasive ventilation (p = 0.001) when compared with the other patient groups. Additionally, CAP patients with COPD had a higher CURB-65 score when compared with CAP patients with asthma (p = 0.004).Conclusions: This study demonstrates that CAP patients with COPD tend to have more severe presentations, while CAP patients with asthma show varied microbial profiles, underscoring the need for patient-specific management strategies in CAP.","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"50 2","pages":"e20230329"},"PeriodicalIF":2.7,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11185154/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141161057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lung ultrasound teaching in medical education: a pilot study at a Brazilian medical school. 医学教育中的肺部超声教学：巴西一所医学院的试点研究。

IF 2.7 4区医学

Jornal Brasileiro De Pneumologia Pub Date : 2024-05-27 eCollection Date: 2024-01-01 DOI: 10.36416/1806-3756/e20230382

Gabrielle Turnes Pereira Demetrio, Ana Cristina Burigo Grumann, Mariângela Pimentel Pincelli, Leonardo Jonck Staub

{"title":"Lung ultrasound teaching in medical education: a pilot study at a Brazilian medical school.","authors":"Gabrielle Turnes Pereira Demetrio, Ana Cristina Burigo Grumann, Mariângela Pimentel Pincelli, Leonardo Jonck Staub","doi":"10.36416/1806-3756/e20230382","DOIUrl":"10.36416/1806-3756/e20230382","url":null,"abstract":"Objective: To evaluate cognitive learning, ability to perform and interpret lung ultrasound exams, and self-perception of learning among medical students after a short pedagogical intervention at a medical school in Brazil.Methods: An experimental pilot study was conducted with medical students at different stages of their education (basic cycle, clinical cycle, and medical internship). The participants underwent a cognitive test before and after the intervention, a practical test, a test to recognize lung ultrasound pathologies, and a qualitative evaluation test at the end of the intervention. Statistical analysis was performed using a significance level of p < 0.05.Results: A total of 42 students were included in the study, with a median age of 23 years and a predominance of males. The mean score of the pre-intervention cognitive test was 2.97 ± 0.87, and that of the post-intervention test was 6.57 ± 1.41, showing significant improvement (p < 0.001). The score of the practical test and that of the recognition of pathologies test also showed significant improvement after the intervention. There was no significant difference in execution time between the groups. Students in the clinical cycle had a better self-perception of learning.Conclusions: Theoretical teaching and practical training of lung ultrasound in a short pedagogical intervention can improve cognitive performance, practical skills, and interpretation of the exam. The level of learning achievement was higher among more advanced students in medical education. Additionally, the students in the clinical cycle had a better perception of their learning.","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"50 2","pages":"e20230382"},"PeriodicalIF":2.7,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11185135/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141160974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lung function and quality of life one year after severe COVID-19 in Brazil. 巴西严重 COVID-19 一年后的肺功能和生活质量。

IF 2.7 4区医学

Jornal Brasileiro De Pneumologia Pub Date : 2024-05-27 eCollection Date: 2024-01-01 DOI: 10.36416/1806-3756/e20230261

Tarciane Aline Prata, Arnaldo Santos Leite, Valéria Maria Augusto, Daniel Cruz Bretas, Bruno Horta Andrade, Jaqueline das Graças Ferreira Oliveira, Aline Priscila Batista, George Luiz Lins Machado-Coelho, Eliane Mancuzo, Carolina Coimbra Marinho

{"title":"Lung function and quality of life one year after severe COVID-19 in Brazil.","authors":"Tarciane Aline Prata, Arnaldo Santos Leite, Valéria Maria Augusto, Daniel Cruz Bretas, Bruno Horta Andrade, Jaqueline das Graças Ferreira Oliveira, Aline Priscila Batista, George Luiz Lins Machado-Coelho, Eliane Mancuzo, Carolina Coimbra Marinho","doi":"10.36416/1806-3756/e20230261","DOIUrl":"10.36416/1806-3756/e20230261","url":null,"abstract":"Objective: To evaluate symptoms, lung function, and quality of life of a cohort of patients hospitalized for severe COVID-19 12 months after hospital admission.Methods: This was a cross-sectional study. We included severe COVID-19 survivors hospitalized in one of three tertiary referral hospitals for COVID-19 in the city of Belo Horizonte, Brazil. Participants were submitted to lung function and six-minute walk tests and completed the EQ-5D-3L questionnaire.Results: The whole sample comprised 189 COVID-19 survivors (mean age = 59.6 ± 13.4 years) who had been admitted to a ward only (n = 96; 50.8%) or to an ICU (n = 93; 49.2%). At 12 months of follow-up, 43% of patients presented with dyspnea, 27% of whom had a restrictive ventilatory disorder and 18% of whom presented with impaired DLCO. There were no significant differences in FVC, FEV1, and TLC between the survivors with or without dyspnea. However, those who still had dyspnea had significantly more impaired DLCO (14.9% vs. 22.4%; p < 0.020) and poorer quality of life.Conclusions: After one year, survivors of severe COVID-19 in a middle-income country still present with high symptom burden, restrictive ventilatory changes, and loss of quality of life. Ongoing follow-up is needed to characterize long COVID-19 and identify strategies to mitigate its consequences.","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"50 2","pages":"e20230261"},"PeriodicalIF":2.7,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11185156/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141160898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical remission after biologic therapy discontinuation in pediatric patients with severe asthma: a case series from a tertiary center. 儿科重症哮喘患者停用生物制剂治疗后的临床缓解：来自一家三级医疗中心的系列病例。

IF 2.7 4区医学

Jornal Brasileiro De Pneumologia Pub Date : 2024-05-27 DOI: 10.36416/1806-3756/e20230405

Giovana De Marchi Castelli, Frederico Friederich, Anasthácia Ferreira Wiemann, Giovana Dos Santos, Paulo Márcio Pitrez

引用次数: 0

Asthma in the Brazilian Unified Health Care System: an epidemiological analysis from 2008 to 2021. 巴西统一医疗系统中的哮喘：2008 年至 2021 年流行病学分析。

IF 2.7 4区医学

Jornal Brasileiro De Pneumologia Pub Date : 2024-05-27 eCollection Date: 2024-01-01 DOI: 10.36416/1806-3756/e20230364

David Halen Araújo Pinheiro, João Victor Hermógenes de Souza, Alberto Fernando Oliveira Justo, Regina Maria Carvalho-Pinto, Fabiano Francisco de Lima, Celso R F Carvalho

{"title":"Asthma in the Brazilian Unified Health Care System: an epidemiological analysis from 2008 to 2021.","authors":"David Halen Araújo Pinheiro, João Victor Hermógenes de Souza, Alberto Fernando Oliveira Justo, Regina Maria Carvalho-Pinto, Fabiano Francisco de Lima, Celso R F Carvalho","doi":"10.36416/1806-3756/e20230364","DOIUrl":"10.36416/1806-3756/e20230364","url":null,"abstract":"Objective: To analyze the number of hospitalizations, the length of hospital stay, and mortality due to asthma, as well as the costs to the Unified Health Care System in Brazil between 2008 and 2021.Methods: This was a cross-sectional epidemiological study using data from the Information Technology Department of the Brazilian Unified Health Care System. Proportional hospitalization and death rates were estimated per 100,000 population by age, microregion, and year.Results: The number of hospitalizations and deaths due to asthma decreased from 2008 to 2021 (205,392 vs. 55,009 and 822 vs. 327, respectively). In addition, a between-sex difference was observed in asthma-related hospitalizations in 2008, and more men were hospitalized in 2021 (51.8%). Asthma mortality rates were similar for both sexes (50.0% each) in 2008, and a slight increase was observed in women's deaths in 2021 (52.9%). Even so, approximately one death/day and more than 55,000 hospitalizations were observed yearly, with a mean length of hospital stay of three days. Additionally, the Southeast region allocated more financial resources to asthma-related hospitalizations.Conclusions: Our results showed that the number of deaths and hospitalizations due to asthma substantially declined during the study period.","PeriodicalId":14845,"journal":{"name":"Jornal Brasileiro De Pneumologia","volume":"50 2","pages":"e20230364"},"PeriodicalIF":2.7,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11185155/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141160799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0