{"title":"Amino acids to prevent cardiac surgery-associated acute kidney injury: a randomized controlled trial.","authors":"Masahiro Kazawa, Daijiro Kabata, Hisako Yoshida, Kimito Minami, Takuma Maeda, Kenji Yoshitani, Hitoshi Matsuda, Ayumi Shintani","doi":"10.1186/s40981-024-00703-6","DOIUrl":"10.1186/s40981-024-00703-6","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to examine the preventive effect of amino acids on postoperative acute kidney injury (AKI).</p><p><strong>Methods: </strong>This was single-center, patient- and assessor-blinded, randomized controlled trial. Patients who underwent aortic surgery with cardiopulmonary bypass were included. The intervention group received 60 g/day of amino acids for up to 3 days. The control group received standard care. The primary outcome was the incidence of AKI. We assessed the effect of amino acids on AKI using a Cox proportional hazards regression model.</p><p><strong>Results: </strong>Sixty-six patients were randomly assigned to the control or intervention group. One patient in the control group withdrew consent after randomization. The incidence of AKI was 10 patients (30.3%) in the intervention group versus 18 patients (56.2%) in the control group (adjusted hazard ratio, 0.44; 95% confidence interval, 0.20-0.95; P = 0.04).</p><p><strong>Conclusions: </strong>This trial demonstrated a significant reduction in AKI incidence with amino acid supplementation.</p><p><strong>Trial registration: </strong>jRCT, jRCTs051210154. Registered 31 December 2021, https://jrct.niph.go.jp/re/reports/detail/69916.</p>","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10963352/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140287439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sustained mitigation of ST-segment elevation in a patient with Brugada syndrome type 1 during sevoflurane and remifentanil anesthesia: a case report.","authors":"Kurumi Saito, Hitoshi Yoshida, Kazuyoshi Hirota","doi":"10.1186/s40981-024-00702-7","DOIUrl":"10.1186/s40981-024-00702-7","url":null,"abstract":"<p><strong>Background: </strong>During general anesthesia, patients with Brugada syndrome are at risk of malignant arrhythmias following worsened ST-segment elevation, potentially leading to sudden cardiac death. The protocol for safe anesthetic management of patients with Brugada syndrome has not yet been established.</p><p><strong>Case presentation: </strong>A 63-year-old man, diagnosed with a spontaneous Brugada type 1 pattern, was scheduled for a pleural biopsy using video-assisted thoracoscopic surgery under general anesthesia. We planned general anesthesia using volatile induction and maintenance anesthesia with sevoflurane and remifentanil. We monitored ST-segment morphology and observed sustained mitigation of ST-segment elevation throughout general anesthesia.</p><p><strong>Conclusion: </strong>The present case may indicate that safe anesthetic management of patients with Brugada syndrome depends on whether the anesthetics used can reduce ST-segment elevation.</p>","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10928048/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140101607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Successful intraoperative management of laparoscopic hysterectomy in a patient with Eisenmenger syndrome: a case report.","authors":"Yuki Maeda, Nami Kakuta, Asuka Kasai, Hiroki Yonezawa, Ryosuke Kawanishi, Katsuya Tanaka","doi":"10.1186/s40981-024-00700-9","DOIUrl":"10.1186/s40981-024-00700-9","url":null,"abstract":"<p><strong>Background: </strong>Patients with Eisenmenger syndrome (ES) requiring noncardiac surgery are at a significantly high risk of perioperative morbidity and mortality. However, perioperative management of patients with ES requiring laparoscopic surgery remains unclear.</p><p><strong>Case presentation: </strong>We describe the case of a patient with ES who underwent laparoscopic hysterectomy under general anesthesia with a peripheral nerve block. The objectives of the perioperative management included the following: (1) maintaining systemic vascular resistance and cardiac output through euvolemia, facilitated by the infusion of noradrenaline, and (2) preventing a reduction in oxygen-carrying capacity and factors that elevate pulmonary vascular resistance, such as pain, hypoxia, and decreased body temperature. Although laparoscopic procedures involved an increased risk in patients with ES, they are less invasive than open surgeries.</p><p><strong>Conclusion: </strong>This report describes the successful anesthetic management of a patient with ES, ensuring a balance between systemic and pulmonary vascular resistance.</p>","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10909790/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140021748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Combination of high-flow nasal oxygen and ketamine/dexmedetomidine sedation for diagnostic catheterization in a child with pulmonary arterial hypertension: a case report","authors":"Kaoru Tsuboi, Misuzu Asai, Toshiki Nakamura, Jun Ninagawa, Hiroshi Ono, Shugo Kasuya","doi":"10.1186/s40981-024-00699-z","DOIUrl":"https://doi.org/10.1186/s40981-024-00699-z","url":null,"abstract":"Pulmonary hypertension is associated with significant risk of perioperative life-threatening events. We present a case of a 12-year-old child with severe pulmonary arterial hypertension who successfully underwent diagnostic cardiac catheterization under ketamine and dexmedetomidine sedation with the support of high-flow nasal oxygen. Ketamine and dexmedetomidine are reported to have minimal effect on pulmonary vasculature in children with pulmonary hypertension and can be safely used in this population along with its lack of respiratory depression. Positive pressure generated by high-flow nasal oxygen improves upper airway patency, prevents micro-atelectasis, and is shown to improve the effectiveness of ventilation and oxygenation in patients under sedation breathing spontaneously. The presented strategy may contribute to enhancing the safety and effectiveness of procedural sedation for children with life-threatening pulmonary hypertension.","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139921567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Left common peroneal nerve palsy caused by cross-legged sitting during epidural labor analgesia: a case report.","authors":"Shunya Ogawa, Hirotsugu Kanda, Hiromichi Kurosaki, Tomoyuki Kawamata","doi":"10.1186/s40981-024-00698-0","DOIUrl":"10.1186/s40981-024-00698-0","url":null,"abstract":"<p><strong>Background: </strong>Nerve injury in epidural labor analgesia can occur with various potential causes. We report a rare case of left common peroneal nerve palsy after delivery caused by a prolonged period of sitting cross-legged during epidural labor.</p><p><strong>Case report: </strong>Epidural labor analgesia in a 28-year-old primipara started at 39 weeks of gestation. She sat cross-legged to prompt delivery for approximately 4 h with a break of a few minutes every hour. She had numbness in her left lower limb and difficulty in dorsiflexion of the ankle joint that did not improve until 3 h after delivery. We made a diagnosis of left common peroneal nerve palsy. Most of the symptoms had improved at 2 months postpartum.</p><p><strong>Conclusion: </strong>Epidural labor analgesia prevented recognition of prolonged peroneal head compression caused by sitting cross-legged. When this position is used to facilitate delivery, it should be released frequently owing to the possibility of a neurologic deficit.</p>","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10879039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139912635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anesthesia management for thoracoscopic resection of a huge intrathoracic meningocele: a case report.","authors":"Ryosuke Nakazawa, Kenichi Masui, Takahisa Goto","doi":"10.1186/s40981-024-00697-1","DOIUrl":"10.1186/s40981-024-00697-1","url":null,"abstract":"<p><strong>Background: </strong>Diagnosed intrathoracic meningocele is an uncommon complication of neurofibromatosis type 1. We report an anesthesia management for a rare case undergoing thoracoscopic resection of a huge intrathoracic meningocele.</p><p><strong>Case presentation: </strong>A 51-year-old woman was scheduled for thoracoscopic meningectomy under general anesthesia. We monitored intrathecal pressure during anesthesia to prevent a decrease in intrathecal pressure. During surgery, the intrathecal pressure occasionally increased by around 5 cmH<sub>2</sub>O immediately after the insertion of the drainage tube and occasionally decreased by up to 10 cmH<sub>2</sub>O during the careful slow aspiration of the cerebrospinal fluid (CSF). The pressure rapidly recovered after the interruption of the procedures. She was discharged on postoperative day 4 without major complications.</p><p><strong>Conclusions: </strong>The CSF pressure was fluctuated by procedures during thoracoscopic resection of a huge meningocele. A CSF pressure monitoring was useful to detect the sudden change of CSF pressure immediately, which can cause intracranial hemorrhage.</p>","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10874914/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139899877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natsuho Haraguchi, Yoshifumi Naito, Masayuki Shibasaki, Teiji Sawa
{"title":"Tracheal injury diagnosed by a sudden increase in end-tidal carbon dioxide levels during mediastinoscopic subtotal esophagectomy: a case report.","authors":"Natsuho Haraguchi, Yoshifumi Naito, Masayuki Shibasaki, Teiji Sawa","doi":"10.1186/s40981-024-00695-3","DOIUrl":"10.1186/s40981-024-00695-3","url":null,"abstract":"<p><strong>Background: </strong>Mediastinoscopic surgery for esophageal cancer facilitates early postoperative recovery. However, it can occasionally cause serious complications. Here, we present the case of a patient with a tracheal injury diagnosed by a sudden increase in end-tidal carbon dioxide (EtCO<sub>2</sub>) during mediastinoscopic subtotal esophagectomy.</p><p><strong>Case presentation: </strong>A 52-year-old man diagnosed with esophageal cancer was scheduled to undergo mediastinoscopic subtotal esophagectomy. During the mediastinoscopic procedure, the EtCO<sub>2</sub> level suddenly increased above 200 mmHg, and the blood pressure dropped below 80 mmHg. We immediately asked the operator to stop insufflation and found a tracheal injury on the right side of the trachea near the carina by bronchoscopy. The endotracheal tube was replaced with a double-lumen tube, and the trachea was repaired via right thoracotomy. There were no further intraoperative complications. After surgery, the patient was extubated and admitted to the intensive care unit.</p><p><strong>Conclusions: </strong>Monitoring EtCO<sub>2</sub> levels and close communication with the operator is important for safely managing sudden tracheal injury during mediastinoscopic esophagectomy.</p>","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10864238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139722648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Successful radiofrequency thermocoagulation of the mandibular nerve for intractable pain associated with medication-related osteonecrosis of the jaw: a case report.","authors":"Sho Shinotsuka, Aiko Maeda, Tomoka Eri, Nozomi Kameyama, Chiaki Yamada, Masako Asada, Ken Yamaura","doi":"10.1186/s40981-024-00696-2","DOIUrl":"10.1186/s40981-024-00696-2","url":null,"abstract":"<p><strong>Background: </strong>Bisphosphonates may cause serious adverse events, including osteonecrosis of the jaw. This article describes a case of successful application of radiofrequency thermocoagulation for pain caused by osteonecrosis of the jaw.</p><p><strong>Case presentation: </strong>An 86-year-old woman who had received alendronate sodium hydrate for osteoporosis was diagnosed with osteonecrosis of the right mandible after dental treatment. Despite repeated conservative and debridement treatments, the patient could not eat due to intractable pain; accordingly, her condition was debilitated. The patient was referred to our pain management clinic for radiofrequency thermocoagulation of the right mandibular nerve. Immediately after the procedure, her pain drastically improved and she could eat; moreover, the pain has not recurred for 3 years.</p><p><strong>Conclusion: </strong>Our findings demonstrate that minimally invasive radiofrequency thermocoagulation may have long-term effects in patients with chronic pain caused by osteonecrosis of the jaw that is refractory to conservative treatment.</p>","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10864227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139722647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analgesic effect of neuromodulation using the AT-04 portable magnetic field-generating device in a patient with neuropathic pain: a case report.","authors":"Atsushi Sawada, Michiaki Yamakage","doi":"10.1186/s40981-024-00694-4","DOIUrl":"10.1186/s40981-024-00694-4","url":null,"abstract":"<p><strong>Background: </strong>Neuromodulation by magnetic field through the AT-04 (ait® (AT-04); Peace of Mind Co., Ltd., Kumamoto, Japan) has improved allodynia in neuropathic pain model rats. This report focuses on neuromodulation through magnetic field exposure using the AT-04 that provided an analgesic effect in a patient with neuropathic pain.</p><p><strong>Case presentation: </strong>A 47-year-old man presented with flaccid paralysis and extensive neuropathic pain and scored 7 on the 11-point Numerical Rating Scale (NRS) for his left upper limb. The patient was treated with neuromodulation by magnetic field exposure using the AT-04. Baseline NRS scores were obtained three times daily during the baseline period (days 1-5). Magnetic field exposure was then performed for 30 min three times daily (morning, noon, and evening) at home for 36 days, which was termed the intervention period (days 6-41). During the baseline period, the median NRS score was 7 and the baseline NRS score for calculating the percentage of nonoverlap data (PND) was 6. During the intervention period, the median NRS score was 4 and the PND value of the NRS score was 77.8% (28/36). Neuromodulation by magnetic field exposure using the AT-04 effectively decreased the patient's NRS score. The patient had no adverse effects during the intervention period.</p><p><strong>Conclusions: </strong>Neuromodulation by magnetic field exposure using the AT-04 was effective in decreasing the NRS score in a patient with neuropathic pain. The AT-04 portable magnetic field-generating device shows potential as a therapeutic option for refractory neuropathic pain.</p>","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10857986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139712236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}