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Retraction Note: Acute coronary syndrome due to left main coronary trunk compression 2 months after left atrial auricle clipping: a case report. 撤稿说明:左心耳剪切术后 2 个月因左冠状动脉主干受压导致的急性冠状动脉综合征:病例报告。
IF 0.9
JA Clinical Reports Pub Date : 2024-06-06 DOI: 10.1186/s40981-024-00719-y
Satoshi Uchida, Daiki Takekawa, Koudai Kato, Kazuyoshi Hirota
{"title":"Retraction Note: Acute coronary syndrome due to left main coronary trunk compression 2 months after left atrial auricle clipping: a case report.","authors":"Satoshi Uchida, Daiki Takekawa, Koudai Kato, Kazuyoshi Hirota","doi":"10.1186/s40981-024-00719-y","DOIUrl":"10.1186/s40981-024-00719-y","url":null,"abstract":"","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":"10 1","pages":"36"},"PeriodicalIF":0.9,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11153474/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141262100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3D transesophageal echocardiographic visualization of the pulmonary artery catheter through the tricuspid valve and their position relative to the tricuspid valve leaflets. 三维经食道超声心动图显示肺动脉导管穿过三尖瓣的情况及其与三尖瓣瓣叶的相对位置。
IF 0.9
JA Clinical Reports Pub Date : 2024-05-30 DOI: 10.1186/s40981-024-00718-z
Shoko Takada, Tomoko Fujimoto, Akiko Tomita-Kobayashi, Yukio Hayashi
{"title":"3D transesophageal echocardiographic visualization of the pulmonary artery catheter through the tricuspid valve and their position relative to the tricuspid valve leaflets.","authors":"Shoko Takada, Tomoko Fujimoto, Akiko Tomita-Kobayashi, Yukio Hayashi","doi":"10.1186/s40981-024-00718-z","DOIUrl":"10.1186/s40981-024-00718-z","url":null,"abstract":"<p><strong>Background: </strong>The tricuspid valve is an atrioventricular valve consisting of three lobes. We used the 3D transesophageal echocardiography to visualize position of the pulmonary artery catheter at the tricuspid valve annulus and examined where the catheter passed through at the level of the tricuspid annulus.</p><p><strong>Methods: </strong>In this prospective and observational study, we monitored the pressure wave on patients undergoing cardiac surgery with the catheter placement by monitoring the pressure waveform for 8 months. We measured the time required for the catheter to pass through the tricuspid and pulmonary valves, respectively. We acquired the 3D image of the tricuspid valve by transesophageal echocardiography and determined the position of the pulmonary artery catheter at the level of the tricuspid annulus. The data were analyzed by Kruskal-Wallis test followed by Mann-Whitney test with Holm multiple comparisons. P < 0.05 was considered significant.</p><p><strong>Results: </strong>Of the 116 cases, the pulmonary artery catheter passed through the tricuspid valve between antero-posterior leaflets in 78 cases (67.2 %), between septal-posterior leaflets in 25 cases (21.6 %), and between antero-septal leaflets in 2 cases (1.7 %) and the center in 11 cases (9.5 %), respectively. The time required for the catheter to pass through the pulmonary valves was significantly different among the catheter positions at the level of the tricuspid annulus.</p><p><strong>Conclusion: </strong>The pulmonary artery catheter location at the level of the tricuspid annulus can be identified using 3D transesophageal echocardiography. The location of the catheter significantly affects the pulmonary artery catheter placement time.</p>","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":"10 1","pages":"35"},"PeriodicalIF":0.9,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11139813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141175635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Remimazolam for general anesthesia in a patient with aortic stenosis and severe obesity undergoing transcatheter aortic valve implantation. 雷马唑仑用于接受经导管主动脉瓣植入术的主动脉瓣狭窄和重度肥胖患者的全身麻醉。
IF 0.9
JA Clinical Reports Pub Date : 2024-05-27 DOI: 10.1186/s40981-024-00716-1
Atsushi Kainuma, Ayaka Koyama, Mao Kinoshita, Jun Iida, Teiji Sawa
{"title":"Remimazolam for general anesthesia in a patient with aortic stenosis and severe obesity undergoing transcatheter aortic valve implantation.","authors":"Atsushi Kainuma, Ayaka Koyama, Mao Kinoshita, Jun Iida, Teiji Sawa","doi":"10.1186/s40981-024-00716-1","DOIUrl":"10.1186/s40981-024-00716-1","url":null,"abstract":"<p><strong>Introduction: </strong>There is currently limited research on the clinical use of remimazolam in severely obese patients. In this report, we describe the anesthesia management of transcatheter aortic valve implantation (TAVI) in a severely obese patient using remimazolam.</p><p><strong>Case description: </strong>A 76-year-old woman (height 1.54 m; total body weight 104 kg; body mass index 43.9 kg/m<sup>2</sup>) was scheduled for TAVI via the femoral artery approach for aortic valve stenosis. Preoperative echocardiography showed an aortic valve peak flow of 4.0 m/s and an effective orifice area of 0.75 cm<sup>2</sup>. Anesthesia induction was performed with a bolus dose of 100 μg fentanyl, 15 mg remimazolam, 60 mg rocuronium, and a continuous infusion of remifentanil at 0.4 mg/h. Intraoperatively, remimazolam was administered at a rate of 35 mg/h. General anesthesia management was completed without any complications, although the patient required temporary catecholamine and inhalation anesthesia assistance due to hemodynamic changes.</p><p><strong>Conclusion: </strong>Owing to its pharmacological advantages, remimazolam may be an option for anesthesia induction and maintenance in severely obese patients with unstable circulation.</p>","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":"10 1","pages":"34"},"PeriodicalIF":0.9,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11128417/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141154464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictive model for post-induction hypotension in patients undergoing transcatheter aortic valve implantation: a retrospective observational study. 经导管主动脉瓣植入术患者诱导后低血压的预测模型:一项回顾性观察研究。
IF 0.9
JA Clinical Reports Pub Date : 2024-05-24 DOI: 10.1186/s40981-024-00717-0
Kohei Noto, Satoshi Uchida, Hirotaka Kinoshita, Daiki Takekawa, Tetsuya Kushikata, Kazuyoshi Hirota
{"title":"Predictive model for post-induction hypotension in patients undergoing transcatheter aortic valve implantation: a retrospective observational study.","authors":"Kohei Noto, Satoshi Uchida, Hirotaka Kinoshita, Daiki Takekawa, Tetsuya Kushikata, Kazuyoshi Hirota","doi":"10.1186/s40981-024-00717-0","DOIUrl":"10.1186/s40981-024-00717-0","url":null,"abstract":"<p><strong>Purpose: </strong>Post-induction hypotension (PIH) is an independent risk factor for prolonged postoperative stay and hospital death. Patients undergoing transcatheter aortic valve implantation (TAVI) are prone to develop PIH. This study aimed to develop a predictive model for PIH in patients undergoing TAVI.</p><p><strong>Methods: </strong>This single-center retrospective observational study included 163 patients who underwent TAVI. PIH was defined as at least one measurement of systolic arterial pressure <90 mmHg or at least one incident of norepinephrine infusion at a rate >6 µg/min from anesthetic induction until 20 min post-induction. Multivariate logistic regression analysis was performed to develop a predictive model for PIH in patients undergoing TAVI.</p><p><strong>Results: </strong>In total, 161 patients were analyzed. The prevalence of PIH was 57.8%. Multivariable logistic regression analysis showed that baseline mean arterial pressure ≥90 mmHg [adjusted odds ratio (aOR): 0.413, 95% confidence interval (95% CI): 0.193-0.887; p=0.023] and higher doses of fentanyl (per 1-µg/kg increase, aOR: 0.619, 95% CI: 0.418-0.915; p=0.016) and ketamine (per 1-mg/kg increase, aOR: 0.163, 95% CI: 0.062-0.430; p=0.002) for induction were significantly associated with lower risk of PIH. A higher dose of propofol (per 1-mg/kg increase, aOR: 3.240, 95% CI: 1.320-7.920; p=0.010) for induction was significantly associated with higher risk of PIH. The area under the curve (AUC) for this model was 0.802.</p><p><strong>Conclusion: </strong>The present study developed predictive models for PIH in patients who underwent TAVI. This model may be helpful for anesthesiologists in preventing PIH in patients undergoing TAVI.</p>","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":"10 1","pages":"33"},"PeriodicalIF":0.9,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11126397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141086778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of pediatric Perthes' disease with unexplained hyperlactatemia at the time of initial surgery and anesthetic management with remimazolam for the subsequent surgery. 一例小儿珀尔特氏病患者在初次手术时出现不明原因的高乳酸血症,并在随后的手术中使用了瑞马唑仑进行麻醉处理。
IF 0.9
JA Clinical Reports Pub Date : 2024-05-24 DOI: 10.1186/s40981-024-00715-2
Ko Ishikawa, Tadanao Hiroki, Sachiko Ito, Chizu Aso, Shigeru Saito
{"title":"A case of pediatric Perthes' disease with unexplained hyperlactatemia at the time of initial surgery and anesthetic management with remimazolam for the subsequent surgery.","authors":"Ko Ishikawa, Tadanao Hiroki, Sachiko Ito, Chizu Aso, Shigeru Saito","doi":"10.1186/s40981-024-00715-2","DOIUrl":"10.1186/s40981-024-00715-2","url":null,"abstract":"<p><strong>Background: </strong>The causes of perioperative hyperlactatemia vary, but they are generally associated with hypoperfusion. Here, we report the case of a pediatric patient who developed unexplained hyperlactatemia during anesthesia with propofol and sevoflurane, which recurred during a second surgery under anesthesia with remimazolam.</p><p><strong>Case presentation: </strong>An 8-year-old boy with Perthes disease and no remarkable past or family history was scheduled for an osteotomy. Anesthesia was induced with propofol and rocuronium and then maintained with sevoflurane and remifentanil. The patient developed lactic acidosis without hemodynamic instability during anesthesia, with a normal lactate/pyruvate ratio after surgery, suggesting a lack of hypoperfusion. We used remimazolam instead of propofol during the second surgery 6 months later, considering the possibility of drug-induced lactic acidosis, including malignant hyperthermia and propofol infusion syndrome, where the unexplained hyperlactatemia recurred.</p><p><strong>Conclusions: </strong>Distinguishing the causes of hyperlactatemia, particularly in the absence of other symptoms, is challenging. The lactate/pyruvate ratio during episodes of hyperlactatemia can provide insights into the underlying pathology.</p>","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":"10 1","pages":"31"},"PeriodicalIF":0.9,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11126548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141086660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment-resistant hiccups during general anesthesia possibly caused by remimazolam: a case report. 可能由瑞咪唑安定引起的全身麻醉期间的治疗抵抗性打嗝:一份病例报告。
IF 0.8
JA Clinical Reports Pub Date : 2024-05-24 DOI: 10.1186/s40981-024-00714-3
Miku Sakurai, Yusuke Matsui, Tomonori Takazawa, Yoji Kabasawa, Wataru Nagumo, Ryo Takada, Shigeru Saito
{"title":"Treatment-resistant hiccups during general anesthesia possibly caused by remimazolam: a case report.","authors":"Miku Sakurai, Yusuke Matsui, Tomonori Takazawa, Yoji Kabasawa, Wataru Nagumo, Ryo Takada, Shigeru Saito","doi":"10.1186/s40981-024-00714-3","DOIUrl":"10.1186/s40981-024-00714-3","url":null,"abstract":"<p><strong>Background: </strong>Previous reports have described hiccups during general anesthesia that were possibly induced by drugs, including benzodiazepines. However, there are few reports of hiccups caused by remimazolam. Case presentation A 75-year-old woman underwent corneal transplantation under general anesthesia with remimazolam. She presented with hiccups once the effects of muscle relaxants used during induction wore off, which persisted even after various treatments, such as the administration of antipsychotic drugs. However, when remimazolam administration was terminated after surgery to awaken the patient, the hiccups stopped and did not recur after extubation. Evaluation of predicted blood levels of remimazolam suggests that higher levels of remimazolam might cause hiccups.</p><p><strong>Conclusion: </strong>Remimazolam might induce hiccups during general anesthesia. Anesthesiologists should consider administering muscle relaxants or changing the anesthetic in cases of refractory hiccups under general anesthesia.</p>","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":"10 1","pages":"32"},"PeriodicalIF":0.8,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11126544/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141086718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A retrospective study of the prevalence of isolated prolongation of activated partial thromboplastin time in the preoperative setting. 一项关于术前活化部分凝血活酶时间个别延长发生率的回顾性研究。
IF 0.9
JA Clinical Reports Pub Date : 2024-05-07 DOI: 10.1186/s40981-024-00713-4
Yasuhiro Watanabe, Yuki Kato, Takayuki Matsuno
{"title":"A retrospective study of the prevalence of isolated prolongation of activated partial thromboplastin time in the preoperative setting.","authors":"Yasuhiro Watanabe, Yuki Kato, Takayuki Matsuno","doi":"10.1186/s40981-024-00713-4","DOIUrl":"10.1186/s40981-024-00713-4","url":null,"abstract":"<p><strong>Background: </strong>Isolated prolongation of activated partial thromboplastin time (APTT) has various causes including inheritable bleeding disorders, and has medical significance as it can lead to the cancelation of surgery. However, even an emergency surgery can be conducted in a patient presenting with severe APTT prolongation, provided careful evaluation and appropriate measures are taken. Hence, the identification of the underlying etiology of the prolonged APTT is crucial. To date, little evidence exists regarding the prevalence of isolated APTT prolongation in Japanese patients undergoing surgery. Herein, we aimed to clarify the prevalence of isolated prolongation of APTT in the preoperative setting and to identify the reasons underlying isolated, severely prolonged APTT.</p><p><strong>Methods: </strong>Preoperative coagulation data of all elective and emergent patients who presented to the anesthetic department between January 1, 2020, and June 30, 2023, were retrospectively collected. Isolated prolongation of APTT was defined as an APTT ≥ 37 s with an international normalized ratio of prothrombin time < 1.2. The underlying etiology of the patient with isolated, severely prolonged APTT (≥ 46 s) was investigated, and canceled surgical procedures in relation to the isolated APTT prolongation were searched.</p><p><strong>Results: </strong>Overall, 10,684 measurements from 9413 patients were included, of which 725 (6.8%) were identified as having isolated APTT prolongation. The reasons for the severely prolonged APTT (n = 60) were miscellaneous, with the most frequently detected etiology being antiphospholipid antibody positivity. Preoperative isolated APTT prolongation contributed to the cancellation of surgery in elective five cases.</p><p><strong>Conclusions: </strong>We clarified the prevalence of preoperative isolated prolongation of APTT. The presence of antiphospholipid antibody was the most frequently detected etiology of the patient with isolated, severely prolonged APTT. The present study provides an important dataset regarding the isolated prolongation of APTT in East Asian patients undergoing surgery.</p>","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":"10 1","pages":"30"},"PeriodicalIF":0.9,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140859014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between perioperative non-steroidal anti-inflammatory drug use and cardiovascular complications after non-cardiac surgery in older adult patients 老年患者非心脏手术后围术期使用非甾体抗炎药与心血管并发症之间的关系
IF 0.9
JA Clinical Reports Pub Date : 2024-04-30 DOI: 10.1186/s40981-024-00712-5
Ryu Komatsu, Michael D. Singleton, Emily M. Dinges, Jiang Wu, Laurent A. Bollag
{"title":"Association between perioperative non-steroidal anti-inflammatory drug use and cardiovascular complications after non-cardiac surgery in older adult patients","authors":"Ryu Komatsu, Michael D. Singleton, Emily M. Dinges, Jiang Wu, Laurent A. Bollag","doi":"10.1186/s40981-024-00712-5","DOIUrl":"https://doi.org/10.1186/s40981-024-00712-5","url":null,"abstract":"We investigated in older adult non-cardiac surgical patients whether receipt of perioperative non-steroidal anti-inflammatory drugs (NSAIDs) is associated with increased incidence of postoperative cardiovascular complications. We retrospectively extracted the information for patients with age ≥ 65 years who had inpatient non-cardiac surgery with a duration of ≥ 1 h from the American College of Surgeons-National Surgical Quality Improvement Program registry data acquired at the University of Washington Medical Center. We compared patients who received NSAIDs perioperatively to those who did not receive NSAIDs, on the two composite outcomes: (1) the incidence of postoperative cardiovascular complications within 30 days of the surgery, and (2) the incidence of combined postoperative gastrointestinal and renal complications, and length of postoperative hospital stay. We used separate multivariable logistic regression models to analyze the two composite outcomes and a Poisson regression model for the length of hospital stay. The receipt of perioperative NSAIDs was not associated with postoperative cardiovascular complications (estimated odds ratio (OR), 1.78; 95% confidence interval (CI), 0.97 to 3.25; P = 0.06), combined renal and gastrointestinal complications (estimated OR, 1.30; 95% CI, 0.53 to 3.20; P = 0.57), and length of postoperative hospital stay in days (incidence rate ratio, 1.06; 95% CI, 0.93 to 1.21; P = 0.39). In older adult non-cardiac surgical patients, receipt of perioperative NSAIDs was not associated with increased incidences of postoperative cardiovascular complications, and renal and gastrointestinal complications within 30 days after surgery, or length of postoperative hospital stay.","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":"48 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140841995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Remimazolam-based total intravenous anesthesia in a patient with a confirmed diagnosis of malignant hyperthermia: a case report 在一名确诊为恶性高热的患者中使用基于雷马唑仑的全静脉麻醉:病例报告
IF 0.9
JA Clinical Reports Pub Date : 2024-04-22 DOI: 10.1186/s40981-024-00710-7
Hiroshi Kondo, Keiko Mukaida, Kurumi Sasai, Yukiko Nao, Ken Hashimoto, Hirotsugu Miyoshi, Rieko Kanzaki, Yasuo M. Tsutsumi
{"title":"Remimazolam-based total intravenous anesthesia in a patient with a confirmed diagnosis of malignant hyperthermia: a case report","authors":"Hiroshi Kondo, Keiko Mukaida, Kurumi Sasai, Yukiko Nao, Ken Hashimoto, Hirotsugu Miyoshi, Rieko Kanzaki, Yasuo M. Tsutsumi","doi":"10.1186/s40981-024-00710-7","DOIUrl":"https://doi.org/10.1186/s40981-024-00710-7","url":null,"abstract":"Malignant hyperthermia (MH) is a rare, life-threatening disorder of calcium homeostasis in skeletal muscle cells that is triggered by volatile anesthetics and succinylcholine, leading to a hypermetabolic reaction. The pathogenic ryanodine receptor 1 (RYR1) gene variant is critical. Patients susceptible to MH should avoid triggering agents, and total intravenous anesthesia (TIVA) is preferred. Remimazolam is safe in patients with suspected MH. We present the first case of remimazolam treatment in a genetically confirmed patient with MH without MH development. A 72-year-old man with a family history of MH underwent remimazolam-based TIVA. After informed consent was obtained, a muscle biopsy and genetic testing were performed. Intraoperatively and postoperatively, the patient exhibited no signs of MH. An enhanced function of the RYR1 channel into releasing calcium was indicated, and the genetic testing revealed a pathogenic variant of RYR1. Remimazolam-based TIVA is safe in patients confirming the diagnosis of MH.","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":"139 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140636356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anesthetic management in pregnant women with Fontan circulation: a case series 方坦循环孕妇的麻醉管理:病例系列
IF 0.9
JA Clinical Reports Pub Date : 2024-04-18 DOI: 10.1186/s40981-024-00706-3
Ai Fujita, Kazuhiro Shirozu, Midoriko Higashi, Ken Yamaura
{"title":"Anesthetic management in pregnant women with Fontan circulation: a case series","authors":"Ai Fujita, Kazuhiro Shirozu, Midoriko Higashi, Ken Yamaura","doi":"10.1186/s40981-024-00706-3","DOIUrl":"https://doi.org/10.1186/s40981-024-00706-3","url":null,"abstract":"Given the advances in medicine, women with Fontan circulation are now reaching childbearing age. However, data on the mode of delivery and anesthetic management of these patients are limited. We report the cases of five pregnant women with Fontan circulation. The mean age at delivery was 28 ± 3 years, and the mean gestational period was 34 weeks and 3 days. Anticoagulation therapy was switched from warfarin and aspirin to continuous intravenous heparin. The modes of delivery were scheduled cesarean section (C/S) in one, emergency C/S in three, and vaginal delivery with epidural labor analgesia in one patient. Three patients underwent C/S under regional anesthesia; one received general anesthesia. The perinatal complications were heart failure, worsening valve regurgitation, and postoperative hematoma in three, four, and two patients, respectively. For C/S in women with Fontan circulation, regional anesthesia should be considered. Epidural labor analgesia can help prevent the decrease in pulmonary blood flow due to straining. We initiated labor analgesia or C/S with regional anesthesia at the appropriate time in four patients.","PeriodicalId":14635,"journal":{"name":"JA Clinical Reports","volume":"140 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140630037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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