JAMA otolaryngology-- head & neck surgery最新文献

{"title":"Patient With Hemoptysis and a Laryngeal Mass.","authors":"Pollara A Cobb, Gregory S Hill, Wojtek K Mydlarz","doi":"10.1001/jamaoto.2025.1560","DOIUrl":"10.1001/jamaoto.2025.1560","url":null,"abstract":"","PeriodicalId":14632,"journal":{"name":"JAMA otolaryngology-- head & neck surgery","volume":" ","pages":"817-818"},"PeriodicalIF":5.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144496680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nosebleeds in Children.","authors":"Alexandra G Espinel","doi":"10.1001/jamaoto.2025.1252","DOIUrl":"10.1001/jamaoto.2025.1252","url":null,"abstract":"","PeriodicalId":14632,"journal":{"name":"JAMA otolaryngology-- head & neck surgery","volume":" ","pages":"828"},"PeriodicalIF":5.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HPV Status and Survival Outcomes in Patients 70 Years and Older After Surgery for Oropharyngeal Carcinoma.","authors":"Paolo Boscolo-Rizzo, Marta Tagliabue, Jerry Polesel, Fabiola Giudici, Vittorio Rampinelli, Giacomo Spinato, Luigi Angelo Vaira, Pawel Golusinski, Didier Dequanter, Carlos Chiesa Estomba, Antonino Maniaci, Mario Lentini, Rita De Berardinis, Laura Iandolo, Daniele Borsetto, Mateusz Szewczyk, Francesco Bussu, Jerome R Lechien, Enzo Emanuelli, Cesare Piazza, Piero Nicolai, Mohssen Ansarin, Giancarlo Tirelli","doi":"10.1001/jamaoto.2025.1722","DOIUrl":"10.1001/jamaoto.2025.1722","url":null,"abstract":"<p><strong>Importance: </strong>The incidence of HPV-associated oropharyngeal squamous cell carcinoma (OPSCC) arising from the palatine tonsil and base of the tongue (BOT) is increasing among the older population. However, data on the prognostic impact of HPV status in patients 70 years and older who undergo up-front surgical treatment remain limited.</p><p><strong>Objective: </strong>To evaluate whether HPV status is associated with survival outcomes in patients 70 years or older undergoing surgical treatment for squamous cell carcinoma (SCC) of the tonsil or BOT.</p><p><strong>Design, setting, and participants: </strong>This was a retrospective cohort analysis including patients 70 years or older at the time of diagnosis with biopsy specimen-proven and surgically resectable SCC of the tonsil or BOT treated in 10 comprehensive cancer centers from January 1, 2010, to July 31, 2021, with a minimum follow-up period of 3 years. Data analysis was conducted from August 20 to December 23, 2024.</p><p><strong>Exposure: </strong>HPV status determined by p16 immunohistochemistry.</p><p><strong>Main outcomes and measures: </strong>Overall survival (OS) and disease-free survival (DFS) were compared between p16-positive and p16-negative groups using Cox proportional hazards models.</p><p><strong>Results: </strong>The analysis included 345 patients (mean [SD] age, 75.7 [4.8] years; 241 [69.9%] male), of whom 207 (60.0%) underwent a transoral surgical approach and 138 (40.0%), an open surgical technique. Of these, 155 patients (44.9%) had p16-positive and 190 (55.1%) had p16-negative test results. The median (IQR) follow-up duration was 55 (18-87) months. Patients with p16-positive tumors demonstrated significantly improved survival outcomes. Specifically, the 5-year OS rate was 71.4% for patients who had p16-positive vs 47.7% for p16-negative test results, with an absolute difference of 23.7% (95% CI, 13.0%-34.4%) and an adjusted hazard ratio (HR) for OS of 0.36 (95% CI, 0.23-0.57). Similarly, the 5-year DFS rate was 66.4% for patients who were p16-positive compared to 40.8% for those p16-negative, with an absolute difference of 25.6% (95% CI, 14.9%-36.3%) and an adjusted HR for DFS of 0.42 (95% CI, 0.28-0.63).</p><p><strong>Conclusions and relevance: </strong>This cohort study found that p16 positivity was associated with significantly improved survival outcomes, suggesting that HPV-associated tumors maintain their favorable prognosis even in patients 70 years and older who were surgically treated for SCC of the tonsil or BOT.</p>","PeriodicalId":14632,"journal":{"name":"JAMA otolaryngology-- head & neck surgery","volume":" ","pages":"795-805"},"PeriodicalIF":5.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12232267/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adjuvant Chemoradiotherapy for Oral Cavity SCC With Minor and Major Extranodal Extension.","authors":"Mirko Manojlovic-Kolarski, Susie Su, Ilian Weinreb, Robert Calvisi, Bayardo Perez-Ordonez, Stephen Smith, Snehal Patel, Cristina Valero, Bin Xu, Ronald Ghossein, Nora Katabi, Jonathan Clark, Tsu-Hui Hubert Low, Ruta Gupta, Evan Graboyes, Joel Davies, Mary Richardson, David Goldstein, Shao Hui Huang, Brian O'Sullivan, Weu Xu, Aaron Hansen, John R de Almeida","doi":"10.1001/jamaoto.2025.1721","DOIUrl":"10.1001/jamaoto.2025.1721","url":null,"abstract":"<p><strong>Importance: </strong>Extranodal extension (ENE) in oral cavity squamous cell carcinoma (OSCC) is a poor prognostic feature and an indication for adjuvant chemoradiotherapy. ENE is stratified into minor (≤2 mm) or major (>2 mm) extent. The role of adjuvant chemoradiotherapy, particularly for the minor ENE subgroup, is unclear.</p><p><strong>Objective: </strong>To determine the impact of adjuvant chemoradiotherapy on oncological outcomes depending on the extent of ENE.</p><p><strong>Design, setting, and participants: </strong>This retrospective, multicenter cohort study was conducted across 4 high-volume head and neck surgery centers in Australia, the US, and Canada. The study included patients with surgically resected OSCC with pathologic positive nodal disease treated between 2005 and 2018. Statistical analysis took place between 2022 and 2025; final follow-up was in 2022.</p><p><strong>Exposures: </strong>Extent of ENE was restaged on archived tissue. Adjuvant radiotherapy or chemoradiotherapy was recommended per standard guidelines.</p><p><strong>Outcomes: </strong>Univariable and multivariable analysis were used to assess the effect of chemotherapy for the entire group and for propensity score-matched cohorts on locoregional control (LRC), disease-free survival (DFS), and overall survival (OS) stratified by minor vs major ENE.</p><p><strong>Results: </strong>A total of 755 patients (mean [SD] age, 61.7 [12.9] years; 36% female) were included in the study: 126 (17%) with minor ENE and 243 (32%) with major ENE. A total of 50 (39.7%) patients with minor ENE and 116 (47.8%) with major ENE received adjuvant chemotherapy. On multivariable analysis, chemotherapy was not associated with improved LRC (hazard ratio [HR], 1.07 [95% CI, 0.49-2.32]), DFS (HR, 0.96 [95% CI, 0.56-1.66]), or OS (HR, 0.97 [95% CI, 0.55-1.73]) in patients with minor ENE. However, in patients with major ENE, chemotherapy improved DFS (HR, 0.58 [95% CI, 0.41-0.81]) and OS (HR, 0.61 [95% CI, 0.38-0.98]). In propensity score-matched cohorts, chemotherapy did not improve LRC (71% vs 75%; difference, 4% [95% CI, -18% to 26%]), DFS (56% vs 56%; difference, 0% [95% CI, -25% to 25%]), or OS (57% vs 57%; difference, 0% [95% CI, -25% to 25%]) for patients with minor ENE, but improved DFS (33% vs 11%; difference, 22% [95% CI, 5%-38%]) and OS (41% vs 15%; difference, 26% [95% CI, 8%-44%]) but not LRC (61% vs 62%; difference, 1% [95% CI, -17% to 21%]) in patients with major ENE.</p><p><strong>Conclusions: </strong>This multicenter cohort study found that in patients with OSCC, adjuvant chemotherapy is beneficial in patients with major ENE, but may not be beneficial in patients with minor ENE.</p>","PeriodicalId":14632,"journal":{"name":"JAMA otolaryngology-- head & neck surgery","volume":" ","pages":"785-794"},"PeriodicalIF":5.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12177724/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144325724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Adolescent With a Tracheal Mass.","authors":"Amanda J Bastien, Matthew T Brigger, Z Jason Qian","doi":"10.1001/jamaoto.2025.1638","DOIUrl":"10.1001/jamaoto.2025.1638","url":null,"abstract":"","PeriodicalId":14632,"journal":{"name":"JAMA otolaryngology-- head & neck surgery","volume":" ","pages":"819-820"},"PeriodicalIF":5.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Updated Thresholds of Basal Calcitonin Level and Extent of Lymph Node Metastasis in Initially Treated Medullary Thyroid Cancer.","authors":"Yuxin Du, Cenkai Shen, Kehan Song, Chuqiao Liu, Zimeng Li, Zhiyan Liu, Yijun Wu, Liang Guo, Yan Zhang, Hao Zhang, Chuang Chen, Min Yin, Haitao Tang, Qinghai Ji, Wenjun Wei, Xiao Shi, Yu Wang","doi":"10.1001/jamaoto.2025.0542","DOIUrl":"10.1001/jamaoto.2025.0542","url":null,"abstract":"<p><strong>Importance: </strong>Calcitonin is the most sensitive and specific biomarker for medullary thyroid cancer (MTC). Basal serum calcitonin levels are strongly associated with the burden of lymph node metastasis (LNM) and can help guide the extent of neck dissection. However, the predictive thresholds for varying degrees of LNM are based on laboratory testing methods no longer in use.</p><p><strong>Objective: </strong>To update the optimal thresholds of basal serum calcitonin levels for predicting the extent of LNM.</p><p><strong>Design, setting, and participants: </strong>This retrospective cohort study included initially treated patients with MTC who had their preoperative basal calcitonin levels tested using electrochemiluminescence or chemiluminescence from a Chinese multicenter cohort of 13 hospitals between 2011 and 2024. The patients were randomly divided into a training and a validation cohort in a 2:1 ratio. The data were analyzed between June 2024 and September 2024.</p><p><strong>Exposures: </strong>Preoperative basal serum calcitonin using electrochemiluminescence or chemiluminescence.</p><p><strong>Main outcomes and measures: </strong>The main outcome is Structural recurrence-free survival (SRFS) based on the group partitioned by the proposed thresholds predicting different LNMs.</p><p><strong>Results: </strong>A total of 509 patients were included in the study with a median (interquartile range [IQR]) follow-up of 52 (27-84) months. The median (IQR) age at diagnosis was 50 (40-59) years, and 279 patients (54.8%) were female individuals. Patients were categorized into 4 groups based on the extent of LNM: no LNM, central LNM, lateral LNM, and upper mediastinal LNM. A positive correlation was found between preoperative calcitonin levels and the extent of LNM (η2 = 0.28). Using the training cohort, preoperative basal calcitonin thresholds associated with different extents of LNM were identified as follows: 241.9 pg/mL for central LNM, 693.9 pg/mL for ipsilateral lateral LNM, 2787.1 pg/mL for upper mediastinal LNM, and 2378.5 pg/mL for bilateral and/or contralateral lateral LNM. In both the training and validation cohorts, the proposed thresholds outperformed those recommended by the American Thyroid Association guidelines not only in the prediction of LNM, but also in the discrimination of SRFS.</p><p><strong>Conclusions: </strong>In this cohort study, updated threshold values of preoperative serum calcitonin predicted different extents of LNM, which may provide optimal cutoffs for future prospective studies on biomarker-guided selective neck dissection in patients with MTC.</p>","PeriodicalId":14632,"journal":{"name":"JAMA otolaryngology-- head & neck surgery","volume":" ","pages":"761-767"},"PeriodicalIF":5.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12203393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144496683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypothermia in Microvascular Head and Neck Reconstruction-Risk of Venous Thromboembolism and Flap Pedicle Thrombosis-Reply.","authors":"Rakan Saadoun, Mario G Solari","doi":"10.1001/jamaoto.2025.1501","DOIUrl":"10.1001/jamaoto.2025.1501","url":null,"abstract":"","PeriodicalId":14632,"journal":{"name":"JAMA otolaryngology-- head & neck surgery","volume":" ","pages":"825-826"},"PeriodicalIF":5.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144325727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Error in Text.","authors":"","doi":"10.1001/jamaoto.2025.2378","DOIUrl":"10.1001/jamaoto.2025.2378","url":null,"abstract":"","PeriodicalId":14632,"journal":{"name":"JAMA otolaryngology-- head & neck surgery","volume":" ","pages":"827"},"PeriodicalIF":5.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12246948/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal Financial Toxicity and Quality of Life in Head and Neck Cancer.","authors":"Leila J Mady, Khalil Baddour, Maryanna S Owoc, Lauren D Kudrick, Alexzandra T Gentsch, David Ebbott, Benjamin Skalla, Maria Amache, Wassim Najjar, Sudip Gupta, Seema Kacker, Angela L Mazul, Carole Fakhry, Kristin L Rising, Richard Hass, Laila A Gharzai","doi":"10.1001/jamaoto.2025.1313","DOIUrl":"10.1001/jamaoto.2025.1313","url":null,"abstract":"<p><strong>Importance: </strong>Patients with head and neck cancer (HNC) are disproportionately affected by financial toxicity (FT). Most research has evaluated FT at a single point.</p><p><strong>Objective: </strong>To evaluate longitudinal factors associated with FT and health-related quality of life in patients and caregivers to understand its progression and effect.</p><p><strong>Design, setting, and participants: </strong>This prospective cohort study was conducted at a single tertiary care center from October 2018 to December 2020. Data were analyzed from December 2020 to December 2024. Eligible participants included adult patients with HNC undergoing definitive treatment and their primary caregivers.</p><p><strong>Exposures: </strong>Surveys conducted at diagnosis, 3 months, and 6 months postdiagnosis. Instruments included the Comprehensive Score for Financial Toxicity, version 1, Financial Distress Questionnaire, University of Washington Quality of Life Scale (UWQOL), version 4 (with physical [PQOL] and social [SQOL] subscales), 19-Item Social Support Survey, and Three-Item Loneliness Scale. Semistructured qualitative interviews were performed at 6 months.</p><p><strong>Main outcomes and measures: </strong>Linear mixed-effects modeling assessed trends in FT (Comprehensive Score for Financial Toxicity), PQOL, and SQOL longitudinally. The McNemar tests compared Financial Distress Questionnaire score among dyads. Qualitative interviews were analyzed using a conventional content analysis.</p><p><strong>Results: </strong>Of 74 enrolled patients (median [range] age, 60 [32-81] years; 12 female individuals [19%]), 64 (86%) completed at least 1 survey, and 41 (64%) participated in interviews. Patients and caregivers reported similar support and loneliness. FT decreased over time (β = 2.77; 95% CI, 1.60-4.33) and older age (β = 0.37; 95% CI, 0.05-0.68) and higher education (β = 13.43; 95% CI, 7.76-18.43) were associated with lower FT, while not working (β = -6.77; 95% CI, -10.31 to -2.96) was associated with worse FT over time. Mixed-effects logistic modeling showed similar odds of high FT over time for patients and caregivers (odds ratio, 1.66; 95% CI, 0.11-273.14). PQOL declined, while SQOL improved longitudinally. Insurance type was the only sociodemographic variable associated with health-related quality of life at diagnosis. Qualitative findings highlighted gaps in treatment expectations, lack of preparedness for financial demands, and the association of FT with employment and caregiving.</p><p><strong>Conclusions and relevance: </strong>The results of this cohort study suggest that age, education level, and employment are associated with FT and its progression. FT is dynamically associated with PQOL and SQOL over time. These findings highlight treatment expectations as a theme contributing to unpreparedness for FT. Interventions to manage physical symptoms, return patients and caregivers to work, and alleviate lower educational attainment an","PeriodicalId":14632,"journal":{"name":"JAMA otolaryngology-- head & neck surgery","volume":" ","pages":"750-760"},"PeriodicalIF":5.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12163717/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social Outcomes Among Adults With Hearing Aids and Cochlear Implants: A Systematic Review and Meta-Analysis.","authors":"Kaitlin Hori, Rishabh Shah, Akhil Paladugu, Tyler J Gallagher, Sophie S Jang, Elizabeth V Weinfurter, Choo Phei Wee, Janet S Choi","doi":"10.1001/jamaoto.2025.1777","DOIUrl":"10.1001/jamaoto.2025.1777","url":null,"abstract":"<p><strong>Importance: </strong>Hearing loss is associated with social isolation and loneliness, which are known to negatively impact mental and cognitive health. However, high-quality evidence on the impact of hearing rehabilitation devices on social outcomes remains limited.</p><p><strong>Objective: </strong>To assess the impact of hearing rehabilitation device use on social outcomes in adults with hearing loss.</p><p><strong>Data sources: </strong>Embase, MEDLINE, Linguistics and Language Behavior Abstracts, CINAHL, and PsycINFO were searched from database inception to March 13, 2024.</p><p><strong>Study selection: </strong>Included studies used a hearing rehabilitation device and compared a validated social outcome score to a baseline or control. Studies with baseline and follow-up scores, including variability measures, were eligible for meta-analysis. Risk of bias was assessed using the Newcastle-Ottawa Scale.</p><p><strong>Data extraction and synthesis: </strong>This systematic review and meta-analysis followed the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) reporting guideline. Two independent reviewers screened studies and extracted data using a standardized template. The meta-analysis used restricted maximum likelihood-based random-effects models to estimate effect sizes.</p><p><strong>Main outcomes and measures: </strong>Hearing rehabilitation devices included hearing aids, cochlear implants, bone conduction hearing aids, and personal sound amplification. The main outcomes included quality of life, isolation, loneliness, and social engagement using the following validated measures: the UCLA Loneliness Scale, Short Form 36, Nijmegen Cochlear Implant Questionnaire, Hearing Handicap Index for the Elderly, Hearing Handicap Index for Adults-Short, Cochlear Implant Quality of Life-35 Profile, Glasgow Benefit Inventory, and World Health Organization Quality of Life.</p><p><strong>Results: </strong>Of 5847 studies screened, 295 underwent full-text review, 65 were included in the systematic review, and 35 in meta-analysis. A total of 5911 participants (weighted mean [SD] age, 64.1 [6.3] years; weighted mean [SD] percentage female, 49.4% [13.9%]) were included among the studies in the systematic review, and 2664 participants (mean age [SD] age, 65.9 [8.3] years; weighted mean [SD] percentage female, 46.3% [13.6%] female) among the studies in the meta-analysis. Hearing rehabilitation with hearing aids or cochlear implants was generally associated with improved social outcomes, including higher social quality of life (QoL) and decreased perceived social handicap and loneliness. The meta-analysis revealed that both hearing aid and cochlear implant use were associated with higher social QoL scores compared to baseline or control groups (SMD, 1.22; 95% CI, 0.88-1.57). Hearing aid use was linked to a moderate improvement in social QoL (SMD, 0.62; 95% CI, 0.13-1.10). Cochlear implant use, for those with moderate to profo","PeriodicalId":14632,"journal":{"name":"JAMA otolaryngology-- head & neck surgery","volume":" ","pages":"806-816"},"PeriodicalIF":5.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12232266/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}