JAMA otolaryngology-- head & neck surgery最新文献

筛选
英文 中文
Longitudinal Growth of Mandated Hearing Aid Benefits in the US. 美国强制性助听器福利的纵向增长。
IF 7 1区 医学
JAMA otolaryngology-- head & neck surgery Pub Date : 2026-10-15 DOI: 10.1001/jamaoto.2026.3143
Michelle L Arnold, Lauren Tonti, Serena Phillips, Stacie P Kershner, Brandy Lipton, Brianna Heslin, Benjamin Ukert, Austin Landini, Michael F Pesko
{"title":"Longitudinal Growth of Mandated Hearing Aid Benefits in the US.","authors":"Michelle L Arnold, Lauren Tonti, Serena Phillips, Stacie P Kershner, Brandy Lipton, Brianna Heslin, Benjamin Ukert, Austin Landini, Michael F Pesko","doi":"10.1001/jamaoto.2026.3143","DOIUrl":"10.1001/jamaoto.2026.3143","url":null,"abstract":"<p><strong>Importance: </strong>Inconsistent hearing aid coverage across US health plans poses substantial barriers to essential care. Prior research has examined private insurance and Medicaid mandates separately, leaving the overall reach of coverage across all major US programs unclear.</p><p><strong>Objective: </strong>To identify mandated hearing aid coverage under private insurance, Medicaid, and federal direct-service programs and to compare coverage for US youth, adults, and older adults by coverage plan and economic indicators.</p><p><strong>Design, setting, and participants: </strong>This cross-sectional study used population-level policy surveillance data with nationally representative insurance data from the American Community Survey (ACS) from 2008 to 2023. ACS respondents were categorized by age (younger than 18 years, 18 to 64 years, and 65 years or older), insurance type (state-level private insurance, Medicaid, and federal direct-service insurance providers), and eligibility for hearing aid coverage. Data were analyzed from February 2024 to August 2026.</p><p><strong>Exposures: </strong>Mandated health coverage for hearing aids through private insurers, Medicaid, US Department of Veterans Affairs, TRICARE, and Indian Health Service.</p><p><strong>Main outcomes and measures: </strong>Annual estimates of the proportion of US individuals with mandated coverage for hearing aids across insurance types, classified into coverage groups. ACS measures included are age, annual household income, and home ownership status.</p><p><strong>Results: </strong>Among 50 203 993 ACS respondents from 2008 to 2023, mandated hearing aid coverage increased from 34.1% (95% CI, 34.0-34.2) to 52.5% (95% CI, 52.4-52.6) among youth younger than 18 years. Among adults aged 18 to 64 years, coverage rose from 10.2% (95% CI, 10.1-10.2) to 19.2% (95% CI, 19.2-19.3), with Medicaid the largest contributor. Mandated coverage for adults 65 years and older declined from 18.5% (95% CI, 18.4-18.6) to 16.9% (95% CI, 16.8-17.0), with Medicaid the primary source. Mandated hearing aid coverage grew 1.03 percentage points (95% CI, 1.02-1.04; P < .001) faster per year among youth younger than 18 years than among adults 65 years and older, largely reflecting consistent Medicaid coverage through the long-standing Early and Periodic Screening, Diagnostic, and Treatment (EPSDT) benefit and the adoption of private insurance pediatric mandates. In 2023, renters and individuals in households below the federal poverty level threshold were more likely to hold mandated coverage than homeowners and those at or above the threshold in every age group.</p><p><strong>Conclusions and relevance: </strong>In this cross-sectional study, despite gradual improvements, substantial gaps remained in mandated hearing aid coverage, particularly for older adults and adults with limited economic resources. Policy reforms, including expanded Medicaid coverage and mandates requiring hearing aid benefits i","PeriodicalId":14632,"journal":{"name":"JAMA otolaryngology-- head & neck surgery","volume":" ","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13673372/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149193564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Facial Synkinesis Resting Phenotypes and Surgical Implications. 面部联动性静息表型和手术意义。
IF 7 1区 医学
JAMA otolaryngology-- head & neck surgery Pub Date : 2026-10-15 DOI: 10.1001/jamaoto.2026.3142
Sahejbir S Bhatia, Christine F Johansen, Devan R Patel, Benjamin Rail, Cristina V Sanchez, MinJae Lee, Diana Tavares-Ferreira, Shai M Rozen
{"title":"Facial Synkinesis Resting Phenotypes and Surgical Implications.","authors":"Sahejbir S Bhatia, Christine F Johansen, Devan R Patel, Benjamin Rail, Cristina V Sanchez, MinJae Lee, Diana Tavares-Ferreira, Shai M Rozen","doi":"10.1001/jamaoto.2026.3142","DOIUrl":"10.1001/jamaoto.2026.3142","url":null,"abstract":"<p><strong>Importance: </strong>Facial synkinesis manifestations are well established, but no trait-based phenotypic stratification exists with implications for static and dynamic treatment planning.</p><p><strong>Objective: </strong>To present clinically observable clusters of resting features in patients with stabilized facial synkinesis with implications for guiding potential static and dynamic treatment considerations.</p><p><strong>Design, setting, and participants: </strong>This single-center retrospective cross-sectional study used videographic and photographic data from January 2009 to March 2025 from a tertiary academic referral center. Inclusion criteria required standardized images and videos captured at least 16 months after facial paralysis onset, prior to synkinesis operations, and at least 3 months following chemodenervation. Patients without all standardized photos and videos or bilateral synkinesis were excluded. Determinations were made by 3 independent evaluators.</p><p><strong>Exposures: </strong>This clustering study of resting phenotypes did not involve any patient exposures.</p><p><strong>Main outcomes and measures: </strong>The primary outcome was classification of patients into clinically observable phenotypic clusters. Secondary outcomes included comparisons of etiological and medical characteristics between the identified phenotypes, with clinician-graded eFACE facial nerve scale scores quantifying facial synkinesis severity.</p><p><strong>Results: </strong>Of 549 consecutive patients with facial synkinesis evaluated, 160 were included in the study. Overall, 128 patients (80%) were female, and the mean (SD) age at paralysis onset was 41 (16) years. Median (IQR) follow-up time was 1.1 (0.2-3.1) years. Mean (SD) eFACE synkinesis score was 53 (16); median time from paralysis onset to evaluation was 5.4 (range, 1.4-36.0) years. Three phenotypes were identified. Type 1, identified in 93 patients (58%), represented notable resting hypertonicity and facial asymmetry, with a mean (SD) eFACE score of 49 (16). Type 2, identified in 47 patients (29%), represented symmetry throughout the face with a mean (SD) eFACE score of 58 (16), which was significantly less severe than type 1 (mean difference, 9 points [95% CI, 3.68-14.48 points]). Type 3, identified in 20 patients (13%), represented localized hypotonicity on the affected side, with a mean (SD) eFACE score of 55 (20). Clustering analysis of dynamic appearance did not yield clinically usable results.</p><p><strong>Conclusions and relevance: </strong>In this cross-sectional study, clinically meaningful clusters of resting facial synkinesis phenotypes represent regional hypertonicity in most cases, symmetry in others, and regional hypotonicity in atypical cases. This phenotypic framework may be useful in systematically evaluating patients and devising static and dynamic surgical treatment strategies.</p>","PeriodicalId":14632,"journal":{"name":"JAMA otolaryngology-- head & neck surgery","volume":" ","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13673379/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149193493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Woman With Palatal Ulcers. 一个患有腭溃疡的女人。
IF 7 1区 医学
JAMA otolaryngology-- head & neck surgery Pub Date : 2026-10-15 DOI: 10.1001/jamaoto.2026.3104
Yong-Wei Fu, Jin-Hao Li
{"title":"A Woman With Palatal Ulcers.","authors":"Yong-Wei Fu, Jin-Hao Li","doi":"10.1001/jamaoto.2026.3104","DOIUrl":"https://doi.org/10.1001/jamaoto.2026.3104","url":null,"abstract":"","PeriodicalId":14632,"journal":{"name":"JAMA otolaryngology-- head & neck surgery","volume":" ","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149192848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validity of the SNOT-22 as a Primary Outcome in Recurrent Acute Rhinosinusitis. SNOT-22作为复发性急性鼻窦炎主要转归的有效性
IF 7 1区 医学
JAMA otolaryngology-- head & neck surgery Pub Date : 2026-10-08 DOI: 10.1001/jamaoto.2026.2996
Isabelle Williams
{"title":"Validity of the SNOT-22 as a Primary Outcome in Recurrent Acute Rhinosinusitis.","authors":"Isabelle Williams","doi":"10.1001/jamaoto.2026.2996","DOIUrl":"https://doi.org/10.1001/jamaoto.2026.2996","url":null,"abstract":"","PeriodicalId":14632,"journal":{"name":"JAMA otolaryngology-- head & neck surgery","volume":" ","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149136683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Precision Phenotyping With Audiometric Data and Gene Discovery for Sensorineural Hearing Loss. 感音神经性听力损失的精确表型与听力测量数据和基因发现。
IF 7 1区 医学
JAMA otolaryngology-- head & neck surgery Pub Date : 2026-10-08 DOI: 10.1001/jamaoto.2026.3089
Andrea J DeFreese, Tanguy Rubat du Mérac, Quanhu Sheng, Srishti Nayak, Taha A Jan
{"title":"Precision Phenotyping With Audiometric Data and Gene Discovery for Sensorineural Hearing Loss.","authors":"Andrea J DeFreese, Tanguy Rubat du Mérac, Quanhu Sheng, Srishti Nayak, Taha A Jan","doi":"10.1001/jamaoto.2026.3089","DOIUrl":"10.1001/jamaoto.2026.3089","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Importance: &lt;/strong&gt;The genetic architecture underlying hearing sensitivity as a quantitative trait is critical for advancing precision medicine in hearing health. Despite extensive genome-wide association study (GWAS) efforts, few strong genetic drivers have been identified.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To compare the sensitivity for detecting genetic variants associated with sensorineural hearing loss (SNHL) using precision phenotyping with pure-tone averages (PTAs) with common phenotyping using diagnostic coding approaches.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Design, setting, and participants: &lt;/strong&gt;In this genetic association study, 2 separate GWASs were conducted using different phenotyping approaches for SNHL: (1) diagnostic code control and (2) precision phenotyping with PTA data. Whole-genome sequencing data from a population with European genetic ancestry collected at a single tertiary center biobank was used. For the control GWAS based on diagnostic codes, case and control participants were defined using primarily International Classification of Diseases, Ninth Revision (ICD-9) and International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10) diagnosis and procedure codes related to SNHL hearing loss. For the precision phenotyping GWAS, hearing status was defined as a continuous variable, using the standard 3-frequency PTA of the better hearing ear from the audiogram. Data analysis was conducted from August 2025 to April 2026.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Main outcomes and measures: &lt;/strong&gt;GWAS summary statistics were used to calculate estimates of single-nucleotide variant (SNV)-based heritability for PTA and ICD phenotypes; to map the genetic risk loci to candidate genes using functional annotation; to evaluate genetic correlations with existing GWASs; and to calculate polygenic risk scores for testing in an independent cohort from the National Institutes of Health's All of Us Research Program.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Overall, 10 164 case participants (mean [SD] age, 63.9 [21.3] years; 5118 [50.4%] female) and 51 305 control participants (mean [SD] age, 51.1 [21.0] years; 28 784 [56.1%] female) were included in the first GWAS; 16 057 participants with PTA (mean [SD] age, 55.5 [21.8] years; 9147 [57.0%] female) were included in the second GWAS. PTA-based GWAS identified 3 genome-wide significant loci mapped to 4 genes: EML6, SPTBN1, ARHGEF28, and EYA4 (SNV-based heritability estimate [h2] = 11.78%; SE = 2.84%). ICD-based GWAS identified no significant loci (h2 = 2.90%; SE = 0.77%). Genome-wide correlations between the PTA-based GWAS and 3 hearing-related ability traits were found (eg, PTA-based GWAS and hearing aid use: r = 0.985; SE = 0.163; P = 1.56 × 10-9). In the All of Us cohort, PTA-derived polygenic risk scores were significantly associated with self-reported deafness (odds ratio [OR], 1.09; 95% CI, 1.07-1.12), whereas ICD-derived scores were not (OR, 1.00; 95% CI, 0.97-1.02).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;C","PeriodicalId":14632,"journal":{"name":"JAMA otolaryngology-- head & neck surgery","volume":" ","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13650696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149136729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Body Composition Metrics and Overall Survival in Head and Neck Cancer Radiotherapy. 头颈部肿瘤放疗的体成分指标和总生存率。
IF 7 1区 医学
JAMA otolaryngology-- head & neck surgery Pub Date : 2026-10-08 DOI: 10.1001/jamaoto.2026.2951
Erika Jank, Chulmin Bang, Vinith B Raj, Jasmine Gillett, Cesar Vincent Villafuerte, Changsuk Oh, Anthony Militchin, Lydia Chau, X Sharon Qi, Robert K Chin, Kyunghyun Sung, Ricky R Savjani
{"title":"Body Composition Metrics and Overall Survival in Head and Neck Cancer Radiotherapy.","authors":"Erika Jank, Chulmin Bang, Vinith B Raj, Jasmine Gillett, Cesar Vincent Villafuerte, Changsuk Oh, Anthony Militchin, Lydia Chau, X Sharon Qi, Robert K Chin, Kyunghyun Sung, Ricky R Savjani","doi":"10.1001/jamaoto.2026.2951","DOIUrl":"10.1001/jamaoto.2026.2951","url":null,"abstract":"<p><strong>Importance: </strong>Advancing the prognostication of patients with head and neck cancer who are undergoing radiotherapy may guide clinicians to better individualize support throughout oncologic treatment.</p><p><strong>Objective: </strong>To evaluate how automated 3-dimensional soft tissue phenotyping, as extracted from routine computed tomography (CT) scans, provides deeper biological granularity into body composition and mortality risk and examine the prognostic utility of baseline body mass index.</p><p><strong>Design, setting, and participants: </strong>This retrospective cohort study evaluated a consecutive sample of patients who were receiving conventionally fractionated definitive-intent radiotherapy for head and neck cancer between January 1, 2014, and December 31, 2024, at a single-center tertiary academic referral center. Cohort filtering was applied to exclude palliative, abbreviated, or nonstandard treatment regimens. Data were analyzed from October 2025 to May 2026.</p><p><strong>Exposures: </strong>Baseline body composition metrics, including body mass index and 3-dimensional volumetric soft tissue indices, extracted automatically from pretreatment CT simulation scans using an open-source deep learning segmentation pipeline.</p><p><strong>Main outcomes and measures: </strong>The primary outcome was overall survival. Multivariable Cox proportional hazards models were used to assess the independent prognostic associations of baseline body mass index and volumetric soft tissue indices, controlling for standard clinical confounders.</p><p><strong>Results: </strong>The primary clinical cohort comprised 1187 patients (median [range] age, 64.0 [5.0-100.0] years; 323 female individuals [27.2%] and 864 male individuals [72.8%]), with an imaging subcohort of 659 patients (55.5%). While elevated body mass index categories were associated with overall survival (overweight: hazard ratio [HR], 0.70; 95% CI, 0.56-0.89; obesity: HR, 0.67; 95% CI, 0.50-0.89), a volumetric analysis revealed that this expansion was disproportionately associated with subcutaneous adiposity gain rather than muscle growth. In the imaging subcohort, elevated skeletal muscle was associated with improved overall survival (HR, 0.67; 95% CI, 0.50-0.89; P = .001). Conversely, elevated intermuscular adiposity was independently associated with an increased mortality risk (HR, 1.28; 95% CI, 1.03-1.58; P = .02).</p><p><strong>Conclusions and relevance: </strong>The results of this cohort study suggest that higher body mass index was associated with improved overall survival. Automated volumetric CT phenotyping revealed that higher skeletal muscle and lower intermuscular adiposity were also associated with improved survival outcomes. This scalable, opportunistic framework may guide pretreatment risk stratification to identify vulnerable patients who may benefit from targeted supportive care.</p>","PeriodicalId":14632,"journal":{"name":"JAMA otolaryngology-- head & neck surgery","volume":" ","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13650697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149136737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validity of the SNOT-22 as a Primary Outcome in Recurrent Acute Rhinosinusitis-Reply. SNOT-22作为复发性急性鼻窦炎主要转归的有效性
IF 7 1区 医学
JAMA otolaryngology-- head & neck surgery Pub Date : 2026-10-08 DOI: 10.1001/jamaoto.2026.2993
Antti Alakärppä, Heidi Kaski, Olli-Pekka Alho
{"title":"Validity of the SNOT-22 as a Primary Outcome in Recurrent Acute Rhinosinusitis-Reply.","authors":"Antti Alakärppä, Heidi Kaski, Olli-Pekka Alho","doi":"10.1001/jamaoto.2026.2993","DOIUrl":"https://doi.org/10.1001/jamaoto.2026.2993","url":null,"abstract":"","PeriodicalId":14632,"journal":{"name":"JAMA otolaryngology-- head & neck surgery","volume":" ","pages":""},"PeriodicalIF":7.0,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149136747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unilateral and Bilateral Hearing Aids for Age-Related Hearing Loss: A Randomized Clinical Trial. 单侧和双侧助听器治疗年龄相关性听力损失:一项随机临床试验。
IF 7 1区 医学
JAMA otolaryngology-- head & neck surgery Pub Date : 2026-10-01 DOI: 10.1001/jamaoto.2026.2401
Sherri L Smith, Todd A Ricketts, Kayla W Kilpatrick, Rebecca North, Janet P Bettger, Theresa Coles, Shari Eberts, Sarah B Peskoe, Howard W Francis, Heather Toth, William Dillon, Laura Thompson, Kjersten Branscome, Amy Walker, Frank W Rockhold
{"title":"Unilateral and Bilateral Hearing Aids for Age-Related Hearing Loss: A Randomized Clinical Trial.","authors":"Sherri L Smith, Todd A Ricketts, Kayla W Kilpatrick, Rebecca North, Janet P Bettger, Theresa Coles, Shari Eberts, Sarah B Peskoe, Howard W Francis, Heather Toth, William Dillon, Laura Thompson, Kjersten Branscome, Amy Walker, Frank W Rockhold","doi":"10.1001/jamaoto.2026.2401","DOIUrl":"10.1001/jamaoto.2026.2401","url":null,"abstract":"<p><strong>Importance: </strong>Age-related hearing loss (ARHL) is ubiquitous and is characterized as bilateral symmetrical sensorineural and mild to moderate in degree. When left untreated, significant impacts arise in domains including communication, psychosocial, cognitive and physical health. Data demonstrating the effectiveness of unilateral or bilateral hearing aids (HAs) as the standard treatment are lacking.</p><p><strong>Objective: </strong>To determine whether bilateral HAs provide more benefit compared with a unilateral HA.</p><p><strong>Design, setting, and participants: </strong>This single-blinded parallel-group randomized clinical trial was conducted at audiology clinics at Duke University Health System and Vanderbilt University from 2021 to 2024 with the primary outcome duration of 3 months. Participants were aged 50 years or older with ARHL with less than 3 months of prior HA use seeking HAs. Participants were randomly assigned to the bilateral or unilateral group. Analyses were based on intention to treat.</p><p><strong>Interventions: </strong>Commercially available prescription receiver-in-the-canal HAs.</p><p><strong>Main outcomes and measures: </strong>The hypothesis was that bilateral HAs would provide greater benefit than a unilateral HA. The primary outcome was HA benefit as measured using the Abbreviated Profile of Hearing Aid Benefit (APHAB) score. Benefit was defined as the difference in APHAB-global score at the 3-month primary end point (aided) from baseline (pretreatment/unaided) APHAB scores. The primary analysis was a linear regression of the APHAB benefit score at 3 months with clinical site and hearing aid assignment as covariates.</p><p><strong>Results: </strong>A total of 275 participants were included (148 female [53.8%]; mean [SD] age, 70.9 [7.9] years). The mean (SD) APHAB benefit score was 14.41 (13.02) for the unilateral group (n = 136) and 19.74 (15.18) for the bilateral group (n = 139). These results indicate that both groups had benefit as demonstrated in APHAB benefit scores, with the bilateral group experiencing significantly higher benefit compared with the unilateral group with a mean difference in APHAB benefit score of -5.29% (95% CI, -8.79% to -1.80%) between the groups.</p><p><strong>Conclusions and relevance: </strong>The trial results indicate that bilateral HAs yield greater self-reported benefit than unilateral HAs; however, while statistically detectable, it is not clear whether this reaches the threshold for clinical meaningfulness. Both configurations produced individually meaningful improvements. These results inform, but do not yet establish, a standard-of-practice recommendation for bilateral fitting.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov Identifier: NCT04739436.</p>","PeriodicalId":14632,"journal":{"name":"JAMA otolaryngology-- head & neck surgery","volume":" ","pages":"970-978"},"PeriodicalIF":7.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13522993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148840197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intentional Imaging for Primary Hyperparathyroidism. 原发性甲状旁腺功能亢进的影像学检查。
IF 7 1区 医学
JAMA otolaryngology-- head & neck surgery Pub Date : 2026-10-01 DOI: 10.1001/jamaoto.2026.2316
Twyla B Bartel, Tracy L Yarbrough, Brendan C Stack
{"title":"Intentional Imaging for Primary Hyperparathyroidism.","authors":"Twyla B Bartel, Tracy L Yarbrough, Brendan C Stack","doi":"10.1001/jamaoto.2026.2316","DOIUrl":"10.1001/jamaoto.2026.2316","url":null,"abstract":"<p><strong>Importance: </strong>Preoperative parathyroid localization has been a great advance in the success of surgery for patients with primary hyperparathyroidism (pHPT) over the past 40 years.</p><p><strong>Objective: </strong>To highlight the amount of radiation exposure from contemporary parathyroid imaging options and to suggest intentional imaging use in planning for parathyroidectomy.</p><p><strong>Evidence review: </strong>Contemporary parathyroid imaging modalities and their respective radiation exposure were reviewed. The analysis focused on patients undergoing preoperative parathyroid imaging related to pHPT and persistent/recurrent pHPT. Exposure of patients to ionizing radiation from devices and radiotracers measured in mSv was reported.</p><p><strong>Findings: </strong>The parathyroid imaging recommendations include ultrasonography (0 mSv), technetium Tc 99m sestamibi single-photon emission computed tomography (SPECT) with or without computed tomography (CT) (8.6-12.1 mSv), and second-line/complex imaging for patients undergoing revision parathyroid surgery: 4-dimensional CT (9.3-20.2 mSv) or choline-based positron emission tomography (PET) with or without CT (6.7-11.8 mSv).</p><p><strong>Conclusions and relevance: </strong>Imaging should be conducted only when the diagnosis is confirmed. When making decisions about imaging, consider radiation exposure, sensitivity/specificity for adenoma detection, local expertise in the imaging modality, and cost.</p>","PeriodicalId":14632,"journal":{"name":"JAMA otolaryngology-- head & neck surgery","volume":" ","pages":"989-991"},"PeriodicalIF":7.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148792936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Routine Postdissection Vagal Nerve Stimulation. 常规解剖后迷走神经刺激。
IF 7 1区 医学
JAMA otolaryngology-- head & neck surgery Pub Date : 2026-10-01 DOI: 10.1001/jamaoto.2026.2282
Keyu Shen, Xiequn Xu
{"title":"Routine Postdissection Vagal Nerve Stimulation.","authors":"Keyu Shen, Xiequn Xu","doi":"10.1001/jamaoto.2026.2282","DOIUrl":"10.1001/jamaoto.2026.2282","url":null,"abstract":"","PeriodicalId":14632,"journal":{"name":"JAMA otolaryngology-- head & neck surgery","volume":" ","pages":"1011"},"PeriodicalIF":7.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148792975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书