JCO oncology practice最新文献

{"title":"Fortifying the Workforce: A National Survey of Hematology/Oncology Fellowship Program Leaders Regarding Training Fellows for Community-Based Careers.","authors":"Anthony Iacoviello, Anika Patel, Shubham Agrawal, Laura E Dodge, Jonathan L Berry, Page Widick, Daniel Aaron Roberts, Rushad Patell, Deepa Rangachari","doi":"10.1200/OP-25-00298","DOIUrl":"https://doi.org/10.1200/OP-25-00298","url":null,"abstract":"<p><strong>Purpose: </strong>Hematology/oncology (HO) care in the United States is predominantly delivered in community-based (CB) settings. We aimed to explore attitudes of HO fellowship program leaders (PLs) surrounding CB-HO training.</p><p><strong>Methods: </strong>We conducted a cross-sectional electronic survey of 194 HO fellowship PLs in the United States. The primary outcome was assessing PLs' attitudes regarding inclusion of CB-HO training during fellowship. Secondary outcomes included assessing whether programs currently have clinical and/or nonclinical training experiences relevant to CB-HO careers.</p><p><strong>Results: </strong>We received 109 responses (response rate, 56.1%) from HO fellowship PLs across the United States. Most fellowship programs (74.3%) are based in tertiary care academic centers, and the largest share (30.3%) are located in the Northeast. A third (33.3%) of PLs indicate that their trainees often pursue CB careers. The majority of respondents (81.6%) believe that CB-HO training should be available for HO trainees, and 60% believe that graduating fellows are adequately prepared for CB careers as is. Roughly two thirds (67%) of PLs provide CB clinical training experiences in their programs currently; 30% offer nonclinical training relevant to CB careers.</p><p><strong>Conclusion: </strong>Although the vast majority of HO training programs in the United States are embedded within academic centers, nearly all respondents indicate training fellows who will pursue careers in the community post-graduation. PLs believe that experiences tailored to CB-HO practice should be available to their fellows. Although many respondents' programs offer CB clinical rotations, rigorous and relevant nonclinical skill development opportunities are lacking. Goal-concordant pathways for career development during HO fellowship can be optimized-particularly as they relate to training individuals to pursue careers in CB settings, a growing need within the HO workforce.</p>","PeriodicalId":14612,"journal":{"name":"JCO oncology practice","volume":" ","pages":"OP2500298"},"PeriodicalIF":4.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144764865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Liability Risks of Ambient Clinical Workflows With Artificial Intelligence for Clinicians, Hospitals, and Manufacturers.","authors":"Sara Gerke, David A Simon, Benjamin R Roman","doi":"10.1200/OP-24-01060","DOIUrl":"https://doi.org/10.1200/OP-24-01060","url":null,"abstract":"","PeriodicalId":14612,"journal":{"name":"JCO oncology practice","volume":" ","pages":"OP2401060"},"PeriodicalIF":4.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144764866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Musician's Experience After Breast Cancer Treatment: Defining Musical Toxicity and its Frequency.","authors":"Jessica F Burlile, Joshua D Cameron, Heather J Gunn, Nicole L Larson, Jennifer L Bradt, Judy C Boughey, Mary M Mrdutt, Fergus J Couch, Janet E Olson, Valerie Cangie, Shawna Ehlers, Yasamin Sharifzadeh, Kathryn J Ruddy, Dean A Shumway, Charles L Loprinzi, Elizabeth J Cathcart-Rake","doi":"10.1200/OP-24-00729","DOIUrl":"10.1200/OP-24-00729","url":null,"abstract":"<p><strong>Purpose: </strong>Over 50% of households in the United States have at least one musician-many musicians are also breast cancer survivors. This group has not been well studied, and given the level of fine sensory-motor skill required for musicianship, we hypothesized that musicians experience unique manifestations of breast cancer treatment toxicities.</p><p><strong>Methods: </strong>A nine-item Musical Toxicity Questionnaire (MTQ) was distributed to patients who had consented to participate in the Mayo Clinic Breast Cancer Registry. The MTQ screened participants by asking if they played a musical instrument or sang in the last 10 years: questions populated for those who answered yes. Respondents were asked if they noticed difficulty with their musical endeavor during or after breast cancer treatment, defined as acute musical toxicity (AMT). The questionnaire asked which side effect and cancer-directed therapy most influenced musical ability, what musical attributes were affected, and the timeline of resolution. Multivariable and classification tree analyses assessed relationships between AMT and treatment characteristics.</p><p><strong>Results: </strong>Of 1,871 survey respondents, 29% (535/1,871) self-identified as musicians. Over a quarter (27%, 144/535) reported AMT, and for 57% (82/144), AMT had not resolved at the time of survey. Of the treatments each participant received, chemotherapy was most often reported as most negatively impactful (63/89 who received chemotherapy, 71%). Decreased endurance was the most common musical difficulty (64% of those with AMT, 92/144), followed by decreased accuracy, trouble playing/singing quickly, and difficulty using proper technique. Multivariable and classification tree analyses revealed that receipt of chemotherapy was most strongly correlated with AMT.</p><p><strong>Conclusion: </strong>These results will help oncology care teams counsel musicians, answer questions about impacts on musicality, and provide a timeline for resolution of musical symptoms.</p>","PeriodicalId":14612,"journal":{"name":"JCO oncology practice","volume":" ","pages":"1142-1152"},"PeriodicalIF":4.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12345839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How Should We Manage the Impact of Antimicrobial Resistance in Patients With Cancer? An Oncological and Infectious Disease Specialist Point of View.","authors":"Angioletta Lasagna, Patrizia Cambieri, Fausto Baldanti, Massimo Andreoni, Francesco Perrone, Paolo Pedrazzoli, Nicola Silvestris","doi":"10.1200/OP-24-00935","DOIUrl":"10.1200/OP-24-00935","url":null,"abstract":"<p><p>Patients with solid tumors present a higher risk of infectious diseases with worse outcomes compared with immunocompetent patients. Prolonged treatment of prophylactic and empirically chosen antibiotics and health care-acquired infections can predispose patients with cancer to infections with antimicrobial-resistant (AMR) organisms. AMR is a global health priority and can affect patients with cancer. The outcome of patients with cancer worsens dramatically if multidrug-resistant (MDR) microorganisms cause infections. Moreover, the emergence of MDR organisms increases health care costs. Antimicrobial stewardship programs can be useful to monitor and improve the use of antibiotics in all oncological settings, including the palliative setting. Awareness of the magnitude of these issues is still low, so it is important to inform and educate oncologists. This narrative review aims to illustrate the main evidence on infections caused by AMR organisms in patients with cancer and the tools that oncologists should have to enhance their multidisciplinary management.</p>","PeriodicalId":14612,"journal":{"name":"JCO oncology practice","volume":" ","pages":"1097-1105"},"PeriodicalIF":4.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What's in the Syringe-Or Isn't: Defining Perioperative Supportive Care Interventions for Improved Surgical Outcomes Among Older Adults With Cancer.","authors":"Ana Berlin","doi":"10.1200/OP-25-00072","DOIUrl":"10.1200/OP-25-00072","url":null,"abstract":"","PeriodicalId":14612,"journal":{"name":"JCO oncology practice","volume":" ","pages":"1057-1059"},"PeriodicalIF":4.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143575734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antimicrobial Stewardship in Patients With Cancer: Interventions and Future Directions to Combat the Rise of Antimicrobial Resistance.","authors":"Aneela Majeed, Thomas Rust","doi":"10.1200/OP-25-00124","DOIUrl":"10.1200/OP-25-00124","url":null,"abstract":"","PeriodicalId":14612,"journal":{"name":"JCO oncology practice","volume":" ","pages":"1067-1069"},"PeriodicalIF":4.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143624512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond the Point: Learning From Outcomes After Inpatient Immune Checkpoint Inhibitor Therapy.","authors":"Ali Raza Khaki, Kerry L Reynolds, Laura A Petrillo","doi":"10.1200/OP-25-00213","DOIUrl":"10.1200/OP-25-00213","url":null,"abstract":"","PeriodicalId":14612,"journal":{"name":"JCO oncology practice","volume":" ","pages":"1063-1066"},"PeriodicalIF":4.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143996400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Oncologist's Guide to Ensuring Your First Medical Grand Rounds Will Be Your Last.","authors":"David H Johnson","doi":"10.1200/OP-25-00120","DOIUrl":"10.1200/OP-25-00120","url":null,"abstract":"","PeriodicalId":14612,"journal":{"name":"JCO oncology practice","volume":" ","pages":"1084-1086"},"PeriodicalIF":4.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143780010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of a Single Item Measure for Financial Toxicity Screening in Patients With Breast Cancer.","authors":"Laila A Gharzai, Leila J Mady, Maria Armache, Zequn Sun, Reshma Jagsi, David Cella, J Devin Peipert, Gelareh Sadigh, Richard W Hass","doi":"10.1200/OP-24-00753","DOIUrl":"10.1200/OP-24-00753","url":null,"abstract":"<p><strong>Purpose: </strong>Financial toxicity (FT) has been linked to higher symptom burden and poorer clinical outcomes for patients with cancer. Despite the availability of validated tools to measure FT, a simple screen remains an unmet need. We evaluated item 12 (\"My illness has been a financial hardship to my family and me\") of the COmprehensive Score for Financial Toxicity (COST) measure as a single-item FT screening measure.</p><p><strong>Methods: </strong>In this secondary analysis, 711 patients with cancer (690 with breast cancer) were recruited via a web-based survey from a philanthropic organization. COST items 1-11 were scored according to Functional Assessment of Chronic Illness Therapy scoring guidelines, with lower scores indicating worse FT. Analyses focused on establishing a correlation, examining item properties, and sensitivity/specificity of item 12 relative to the total COST score.</p><p><strong>Results: </strong>Item 12 had a correlation of <i>r</i> = 0.53 with the COST-11 score, and an increase of one point on item 12 is associated with a decrease of approximately three total points on the full scale (<i>b</i>, 3.35; <i>P</i> < .001; adjusted <i>R</i>², 0.28). Item analysis with the graded-response item in response theory modeling showed very good discrimination (<i>a</i>, 2.096) for item 12, indicating that it can reliably distinguish between low and high FT in patients. Sensitivity ranged between 75.6% and 95.7% on all item 12 thresholds to screen positive for FT using two COST cutoffs as criteria. Maximizing both sensitivity and specificity was to be found for higher item 12 scores.</p><p><strong>Conclusion: </strong>To our knowledge, this is the first validation of a single-item screening measure for FT. Overall, these results illustrate that item 12 from the COST measure is a good candidate for a single-item screener. Clinicians can choose among item 12 screening thresholds depending on their tolerance for low specificity.</p>","PeriodicalId":14612,"journal":{"name":"JCO oncology practice","volume":" ","pages":"1134-1141"},"PeriodicalIF":4.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Virtual Second-Opinion Delivery for Oncology Patients.","authors":"Aadit P Shah, Siyu Shi, Thomas Y Sun, Manali I Patel, Sumit A Shah","doi":"10.1200/OP.24.00392","DOIUrl":"10.1200/OP.24.00392","url":null,"abstract":"<p><strong>Purpose: </strong>Patients with cancer face increasing difficulty securing access to timely, quality oncologic care. A virtual consultation program at a tertiary academic center could eliminate physical barriers while providing treatment recommendations that could be executed locally.</p><p><strong>Methods: </strong>We evaluated an <i>Online Second Opinions Program</i> to increase access to expert care via a cloud-based platform through Included Health. This program was open to any patient globally who had a local treating physician. Patient records were compiled and sent to a disease expert at Stanford Healthcare. A report detailing an assessment and treatment recommendation was then returned within 3 days. We analyzed the characteristics of the patient base and the frequency with which treatment change was recommended.</p><p><strong>Results: </strong>Between November 2018 and August 2020, 657 patients participated in the program. The majority of patients were female (58.4%) with a mean age of 60 years. A majority lived out-of-state (62%, with 24.7% of total patients from outside the United States) and had advanced disease (77.2% diagnosed at stage III or IV). Breast cancer was the most common diagnosis (24.7%). Physicians providing the virtual service were primarily medical oncologists (67.6%) and reported to have recommended a treatment change in more than half of the cases reviewed (53.8%). A treatment change was most often recommended for patients with stage II disease (64%), and least often for stage I and III disease (both 45%).</p><p><strong>Conclusion: </strong>To our knowledge, this is one of the first studies to describe patients who use virtual second-opinion programs for oncology, showing that more than half of the patients were recommended to have a treatment change. Although patients most often had advanced disease, those with stage II disease most often received a treatment change recommendation.</p>","PeriodicalId":14612,"journal":{"name":"JCO oncology practice","volume":" ","pages":"1118-1123"},"PeriodicalIF":4.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}