JAC-Antimicrobial Resistance最新文献

{"title":"Resistance to empirical antibiotics in urinary tract infections caused by Enterobacterales in the East of England.","authors":"Stuart Drazich-Taylor, Catherine Dominic, James Moore, Ashley Craine, Davis Nwaka","doi":"10.1093/jacamr/dlaf003","DOIUrl":"10.1093/jacamr/dlaf003","url":null,"abstract":"<p><strong>Objectives: </strong>To characterize resistance rates in urinary tract infections caused by Enterobacterales to first- and second-line antibiotics.</p><p><strong>Methods: </strong>Positive urine cultures examined by the Eastern Pathology Alliance network from September 2018 to September 2023 were retrospectively analysed. Enterobacterales from non-pregnant adults were included. Resistance to cefalexin, nitrofurantoin, trimethoprim, pivmecillinam and fosfomycin was investigated.</p><p><strong>Results: </strong>A total of 193 137 samples from 99 635 patients met inclusion criteria. The mean number of episodes per patient was 1.94, with a range of 1-55 episodes over the 5 year period. Patients were predominantly of female sex (76.6%) and of an older age (mean age 66.4 ± 19.5 SD). <i>Escherichia coli</i> was the commonest organism isolated (73%) followed by undifferentiated coliforms (16%), <i>Proteus</i> spp. (6%) and <i>Klebsiella pneumoniae</i> (2%). Across all samples, trimethoprim resistance was high at 27%, with lower cefalexin (8.3%) and nitrofurantoin (8.8%) resistance. Resistance to two or three of the first-line antibiotics-trimethoprim, cefalexin and nitrofurantoin-was 5.5% and 0.6%, respectively. In <i>E. coli</i> there was low fosfomycin resistance at 3.1%. In resistant isolates subject to extended sensitivity testing, moderate pivmecillinam (21%) resistance was demonstrated. Organisms demonstrating AmpC and ESBL resistance were detected in 3.2% and 3.5% of isolates. Trimethoprim resistance was highest at James Paget University Hospital (37%) and surrounding general practices (30%).</p><p><strong>Conclusions: </strong>This study illustrates resistance rates to commonly prescribed antibiotics for urinary tract infections in Norfolk and Waveney. Adjustments to local empirical antibiotic guidelines have been shaped by the resistance rates demonstrated herein.</p>","PeriodicalId":14594,"journal":{"name":"JAC-Antimicrobial Resistance","volume":"7 1","pages":"dlaf003"},"PeriodicalIF":3.7,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11752643/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Country of origin and prices of systemic antibiotics in Vietnam: a multicentre retrospective study.","authors":"Vu Quoc Dat","doi":"10.1093/jacamr/dlae221","DOIUrl":"10.1093/jacamr/dlae221","url":null,"abstract":"<p><strong>Background: </strong>Local production of antibiotics is essential for improving access to treatment of clinical infection and avoiding vulnerability to expensive drug imports.</p><p><strong>Objectives: </strong>To describe the country of origin and cost of antibiotics in Vietnam.</p><p><strong>Methods: </strong>This was an observational study. Antibiotic procurement in 372 healthcare facilities in Vietnam between 2018 and 2022 were included in this analysis. Antibiotics were classified using the Anatomical Therapeutic Chemical Index and the 2021 WHO Access, Watch and Reserve groups. The country of origin of antibiotics was determined by the place where the final products were manufactured. Antibiotic costs were estimated in US dollars per DDD and adjusted by annual inflation.</p><p><strong>Results: </strong>This study included 2.54 billion antibiotic DDDs, totalling 3.13 billion US dollars. Local production accounted for 80.2% of the number of DDDs and 43.4% of the total expenditure. The antibiotics from other countries were driven by imports from high-income countries, which accounted for 75.5% of DDDs and 89.6% of the expenditure on imported antibiotics. Availability of Reserve group antibiotics was more dependent on imports from high-income countries (36.6% of DDDs) than those of Access (15.7% of DDDs) and Watch group antibiotics (14.2% of DDDs).</p><p><strong>Conclusions: </strong>A comprehensive policy approach is needed to ensure the affordability and to reduce dependency on imported Reserve group antibiotics.</p>","PeriodicalId":14594,"journal":{"name":"JAC-Antimicrobial Resistance","volume":"7 1","pages":"dlae221"},"PeriodicalIF":3.7,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11735462/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploration of interprofessional collaboration for the diagnosis of infections and antibiotic prescription in nursing homes using multiple case study observational research.","authors":"Damien Gonthier, Laetitia Ricci, Marie Buzzi, Gabriel Birgand, Joëlle Kivits, Nelly Agrinier","doi":"10.1093/jacamr/dlae205","DOIUrl":"10.1093/jacamr/dlae205","url":null,"abstract":"<p><strong>Background: </strong>Antibiotic resistance in nursing homes (NHs) is inconsistently tackled by antimicrobial stewardship programmes. The literature on individual determinants of antibiotic prescriptions (APs) in NHs is extensive. However, less is known about the structural determinants of AP in NHs.</p><p><strong>Objectives: </strong>To examine how different organizational contexts influenced interprofessional collaboration in the diagnosis and treatment of infections in NHs.</p><p><strong>Methods: </strong>We conducted multiple case study observational research through field notes and sketches from pictures of NH layouts.</p><p><strong>Results: </strong>We observed three NHs for 10 days (i.e. 82 h). We inductively identified four successive steps: (i) trigger by an assistant nurse, (ii) internal decision-making, (iii) calling on an external general practitioner (GP) and (iv) GP intervention. Diagnosis and treatment of infections involved various degrees of interprofessional collaboration within NHs, resulting in a range of actions, more or less directly involving AP by external GPs. In the case of onsite AP, external GPs barely relied on information about residents provided by NH professionals and did not provide any feedback regarding their decision, resulting in limited interprofessional collaboration. In contrast, remote AP (through phone calls) relied on interprofessional collaboration through mandatory exchanges between external GPs and NH nurses about the resident's symptoms and signs.</p><p><strong>Conclusions: </strong>Diagnosis and treatment of infections through AP involved two distinct organization types (institutional versus private practices) and often lacked interprofessional collaboration. Future antimicrobial stewardship in NHs should consider (i) improving the connection between these two organizations and (ii) developing tools to support remote interprofessional collaboration to sustain prescription.</p>","PeriodicalId":14594,"journal":{"name":"JAC-Antimicrobial Resistance","volume":"7 1","pages":"dlae205"},"PeriodicalIF":3.7,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11725391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142978437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibiotic use at the Centre Hospitalier Universitaire de Zone d'Abomey Calavi/Sô-Ava (CHUZ/AS) in Benin: a point prevalence survey.","authors":"Morelle Sèssiwèdé Gnimavo, Bawa Boya, Steward Mudenda, Aurel Constant Allabi","doi":"10.1093/jacamr/dlae220","DOIUrl":"10.1093/jacamr/dlae220","url":null,"abstract":"<p><strong>Background: </strong>Antimicrobial stewardship promotes the appropriate use of antibiotics to prevent the emergence and spread of antimicrobial resistance. This study evaluated the use of antibiotics using a point prevalence survey at the Centre Hospitalier Universitaire de Zone d'Abomey Calavi/Sô-Ava (CHUZ/AS) in Benin.</p><p><strong>Methods: </strong>This cross-sectional study utilized the WHO point prevalence survey methodology for monitoring antibiotic use among inpatients in hospitals. The survey was conducted from 11 January 2022 to 19 January 2022 among hospitalized patients before 8:00 a.m. on the day of the survey.</p><p><strong>Results: </strong>Of the 111 inpatient medical files reviewed, the prevalence of antibiotic use was 82.9%. The number of antibiotics received per patient ranged from 1 to 5, with a mean of 2.45 ± 1.11 and a median of 2. The most commonly prescribed class of antibiotics was beta-lactams (46.7%), aminoglycosides (20.6%) and nitroimidazoles (19.7%). According to the WHO AWaRe classification, 30.4% of inpatients received the Access group of antibiotics and 44% received a combination of Access and Watch group antibiotics; treatment was empiric in 94.5% of encounters. Only 22.7% of patients were treated based on microbiological examination/culture and sensitivity testing.</p><p><strong>Conclusions: </strong>This study found a high prevalence of antibiotic use among inpatients at the CHUZ/AS Tertiary Care Hospital in Benin. The most prescribed antibiotics were ampicillin, metronidazole and ceftriaxone. Consequently, the study found a low use of culture and sensitivity testing to guide treatment, particularly in the paediatric and surgical population, and the preference for broad-spectrum antibiotics suggests that antibiotic use at the CHUZ/AS Tertiary Care is not optimal. Therefore, antimicrobial stewardship programmes, policies and guidelines must be instigated and strengthened to address these gaps and promote rational use of antibiotics.</p>","PeriodicalId":14594,"journal":{"name":"JAC-Antimicrobial Resistance","volume":"7 1","pages":"dlae220"},"PeriodicalIF":3.7,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11719636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and factors associated with TB among presumptive TB patients in war-affected areas of North Wollo, Ethiopia.","authors":"Zelalem Asmare, Abebe Assefa, Amanuel Belay, Ayehu Mulie, Dawit Aschil, Yalewayker Gashaw","doi":"10.1093/jacamr/dlae206","DOIUrl":"10.1093/jacamr/dlae206","url":null,"abstract":"<p><strong>Background: </strong>TB is a leading infectious disease globally, with war and displacement significantly increasing its burden. In Ethiopia, ongoing conflict and displacement have worsened health conditions, yet data on TB prevalence and resistance remain scarce. This study aimed to determine the prevalence of TB, rifampicin-resistant TB (RR-TB), and associated factors among presumptive TB patients in hospitals during the ongoing crisis.</p><p><strong>Methods: </strong>A cross-sectional study was conducted with 273 presumptive TB participants, recruited via convenience sampling. Data on socio-demographic and behavioural factors were collected through interviews using a pre-tested structured questionnaire. Sputum samples were examined using the Xpert MTB/RIF molecular assay. Binary logistic regression was used to analyse the association between independent variables and TB. Variables with a <i>P</i> value  ≤0.25 in the univariate analysis were included in the multivariable regression to identify independent predictors, with a <i>P</i> value ≤0.05 considered statistically significant.</p><p><strong>Results: </strong>Among the 273 study participants, 47 were confirmed to have <i>Mycobacterium tuberculosis</i>, resulting in a prevalence of 17.2%. Of the 47 patients diagnosed with <i>M. tuberculosis</i>, 17 (36.2%) were found to have rifampicin-resistant strains. Previous contact with displaced persons [adjusted odds ratio (AOR): 4.237; 95% CI: 1.67-10.762; <i>P</i> value: 0.002), contact with TB-infected individuals (AOR: 5.644; 95% CI: 2.46-12.96; <i>P</i> value: <0.01) and being HIV positive (AOR: 3.074; 95% CI: 1.26-7.50; <i>P</i> value: 0.014) were the significant predictors for TB.</p><p><strong>Conclusions: </strong>Our study revealed a troubling prevalence of RR-TB, underscoring the adverse effects of war and displacement on healthcare services. Significant associations with predictors like HIV infection and close contact with TB-infected individuals necessitate targeted interventions.</p>","PeriodicalId":14594,"journal":{"name":"JAC-Antimicrobial Resistance","volume":"7 1","pages":"dlae206"},"PeriodicalIF":3.7,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11694660/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142921709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antifungal stewardship in the UK: where are we now?","authors":"Silke Schelenz, Samir Agrawal, Aaron Brady, Gillian Kiely, Zeshan Riaz, Emilie Howes, Tim Felton, Christianne Micallef, Netta Tyler, Tihana Bicanic, P Lewis White","doi":"10.1093/jacamr/dlae209","DOIUrl":"10.1093/jacamr/dlae209","url":null,"abstract":"<p><strong>Background: </strong>Antifungal stewardship (AFS) is the judicious use of today's antifungal agents with the aim of improving patient outcomes and preserving their future effectiveness. Antifungal resistance (AFR) is increasing globally, with more patients at risk of Invasive Fungal Disease (IFD), highlighting the urgent need to standardize AFS practices in the UK. The aim of this position paper is to understand the current AFS landscape in the UK.</p><p><strong>Methods: </strong>A virtual panel discussion was held from September to October 2023 on an online platform followed by a virtual meeting with nine healthcare professionals from across the UK selected for their expertise on IFD management and AFS. The discussion was structured across four topics: current AFS landscape, key elements of an AFS programme, diagnostics and diagnostic stewardship, and unmet needs in education and training. A thematic analysis was carried out. The results represent the collated and summarized views from these activities.</p><p><strong>Results and discussion: </strong>Participants reported barriers to implementing AFS and its integration within antimicrobial stewardship (AMS) programmes in the UK. The primary challenge identified was a lack of resources, including funding and staff time. Sub-optimal fungal diagnostics and limited mycology expertise was reported as a barrier to AFS, clinical IFD and AFR surveillance. Approaches to combatting these challenges may include investing in formal mycology networks to serve as centres of clinical expertise and diagnostic hubs.</p><p><strong>Conclusion: </strong>National standards for AFS services and associated outcome metrics need to be established to set a benchmark for centres to improve AFS.</p>","PeriodicalId":14594,"journal":{"name":"JAC-Antimicrobial Resistance","volume":"7 1","pages":"dlae209"},"PeriodicalIF":3.7,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11685713/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142914744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular characterization of antibiotic resistance in bacteria from daycare centres in Ile-Ife, Nigeria.","authors":"Eunice Damilola Wilkie, Jude Oluwapelumi Alao, Oluwakemi Abike Thonda, Anthonia Olufunke Oluduro","doi":"10.1093/jacamr/dlae213","DOIUrl":"10.1093/jacamr/dlae213","url":null,"abstract":"<p><strong>Background: </strong>Antibiotic resistance is an escalating global health issue, with particularly severe implications in low- and middle-income countries (LMICs) such as Nigeria. This study examines antibiotic-resistant bacteria's prevalence and molecular characteristics in daycare centres in Ile-Ife, Nigeria, where high antibiotic use and limited infection control measures present significant challenges.</p><p><strong>Methods: </strong>Between November 2017 and July 2019, samples were collected from 20 daycare centres, including swabs from fomites and children. Bacterial isolates were identified and assessed for antibiotic susceptibility using standard methods. Molecular techniques, including PCR, were employed to detect resistance genes such as <i>blaSHV</i>, <i>tetA</i>, <i>dfr1</i> and <i>mecA</i>.</p><p><strong>Results: </strong>The study found high resistance levels among common pathogens, with <i>S. aureus</i> and other staphylococci showing significant resistance to ampicillin and Augmentin and Gram-negative bacteria exhibiting broad resistance patterns. Resistance genes, including <i>blaSHV</i> and <i>mecA</i>, were identified in multiple isolates, indicating the spread of crucial resistance mechanisms.</p><p><strong>Conclusions: </strong>The results highlight the critical need for improved surveillance, targeted antimicrobial stewardship and enhanced infection control practices in daycare centres to address the growing threat of antibiotic resistance. This research offers valuable insights into resistance dynamics in paediatric settings and supports the development of strategies to manage the spread of resistant bacteria in LMIC contexts.</p>","PeriodicalId":14594,"journal":{"name":"JAC-Antimicrobial Resistance","volume":"7 1","pages":"dlae213"},"PeriodicalIF":3.7,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11683008/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142907183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Doctors' perceptions of antimicrobial resistance in the Northern West Bank, Palestine: a qualitative study.","authors":"Lotta Gustafsson, Zaher Nazzal, Connie Mary Wiskin, Souad Belkebir, Shameq Sayeed, Alix Wood","doi":"10.1093/jacamr/dlae198","DOIUrl":"10.1093/jacamr/dlae198","url":null,"abstract":"<p><strong>Objectives: </strong>In the West Bank, antimicrobial resistance (AMR) is increasingly and alarmingly common. Efforts are being made to introduce antimicrobial stewardship programmes (ASPs). This study explores doctors' perceptions of AMR and context-specific barriers and facilitators to ASPs at a critical point in national ASP development.</p><p><strong>Methods: </strong>Semi-structured interviews were conducted with 22 doctors working in primary healthcare, government and non-governmental hospitals in Nablus in 2019. Two researchers thematically analysed the data.</p><p><strong>Results: </strong>Participants recognized antibiotic resistance as a major threat to health. Few felt that doctors were well informed about ASPs; many had not heard of them. However, there was willingness to expand and begin new education programmes. Barriers and facilitators to ASPs included: (i) doctors were perceived to 'misuse' antibiotics, lack awareness, favour short-term outcomes, and externalize blame; (ii) patients reportedly treat antibiotics 'like analgesia' with high expectations of doctors; (iii) resource limitations make ASPs and infection control difficult-a lack of drugs, laboratory services, infectious disease specialists, and research to develop local guidelines; and (iv) top-down policy is recommended to restrict access to antibiotics without a prescription, but should be coupled with support, collaboration and community action.</p><p><strong>Conclusions: </strong>Doctors' appreciation of the severity of the issue, and willingness for the expansion of existing programmes targeted at their own prescribing practices, provides a strong foundation for successful ASPs. A top-down approach to prevent inappropriate antibiotic prescribing is welcomed by participating doctors. If financial and resource limitations could be addressed, a continued multifaceted approach may enable physician, pharmacist and patient behaviours to change.</p>","PeriodicalId":14594,"journal":{"name":"JAC-Antimicrobial Resistance","volume":"7 1","pages":"dlae198"},"PeriodicalIF":3.7,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11670781/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacterial growth and antimicrobial resistance in urinary <i>Escherichia coli</i> isolates among men with lower UTI in Swedish primary healthcare: retrospective data over a 4 year period.","authors":"Helena Kornfält Isberg, Martin Sundqvist, Eva Melander, Anders Beckman, Katarina Hedin","doi":"10.1093/jacamr/dlae214","DOIUrl":"10.1093/jacamr/dlae214","url":null,"abstract":"<p><strong>Background: </strong><i>Escherichia coli</i>, the most common bacterium causing urinary tract infections (UTIs), is increasingly reported as resistant to multiple antibiotics. Swedish surveillance data from hospital and primary health care (PHC) report a 17%-19% prevalence of resistance to ciprofloxacin in <i>E. coli</i> from urine cultures in men over 20 years of age. Surveillance data may include nosocomial infections. However, few studies have described resistance in <i>E. coli</i> in men with community-acquired UTI in PHC. We aimed to describe the microbiological results, including antibiotic resistance in <i>E. coli</i>, in men with lower UTI (LUTI) attending PHC.</p><p><strong>Methods: </strong>In this retrospective study based on information from electronic medical records, we included patients from 289 PHC centres. For all men aged 18-79 years diagnosed with LUTI in PHC from January 2012 to December 2015, we extracted data on age, UTI diagnosis and results from urine cultures.</p><p><strong>Results: </strong>A total of 17 987 episodes of lower UTI were identified. <i>E. coli</i> was detected in 62% of positive cultures and 63% of detected <i>E. coli</i> isolates were susceptible to all tested antimicrobials. Resistance in <i>E. coli</i> to the first-choice antibiotics pivmecillinam and nitrofurantoin were 2% and 1%, respectively. Resistance to ciprofloxacin was 9%, and to trimethoprim it was 17%.</p><p><strong>Conclusions: </strong>Resistance levels for ciprofloxacin in <i>E. coli</i> among men with LUTI in PHC were lower than in surveillance data. The results of this study point to the importance of surveillance of resistance in urine samples from patients with LUTI in PHC in order to choose the right empirical antibiotic treatment.</p>","PeriodicalId":14594,"journal":{"name":"JAC-Antimicrobial Resistance","volume":"7 1","pages":"dlae214"},"PeriodicalIF":3.7,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11670775/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mentorship advances antimicrobial use surveillance systems in low- and middle-income countries.","authors":"Kiran Sunder Bajracharya, Susan Luu, Ron Cheah, Santosh Kc, Atifa Mushtaq, Marjorie Elijah, Bhupendra Kumar Poudel, Celeste Fernandes Xavier Cham, Shyamu Mandal, Stephen Muhi, Kirsty Buising","doi":"10.1093/jacamr/dlae212","DOIUrl":"10.1093/jacamr/dlae212","url":null,"abstract":"<p><p>A shortage of trained personnel poses significant challenges to implementing antimicrobial use (AMU) surveillance systems in low- and middle-income countries (LMICs). Traditional training models, such as workshops, seminars and online courses, often lack the sustained engagement and support necessary for deep learning and skill mastery. This article advocates for mentorship as an effective training method for AMU professionals in LMICs. Drawing on our experiences as mentors and mentees from 1- to 2-year mentorship programmes in Nepal, Pakistan, Papua New Guinea and Timor-Leste between 2019 and 2023, we highlight the challenges and success factors of mentorship. Our insights demonstrate mentorship's value in building expertise and sustaining capacity in AMU surveillance, offering a promising solution to address the personnel shortage in these regions.</p>","PeriodicalId":14594,"journal":{"name":"JAC-Antimicrobial Resistance","volume":"7 1","pages":"dlae212"},"PeriodicalIF":3.7,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11670778/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}