{"title":"Chemical toxicity of thorium in Saccharomyces cerevisiae","authors":"Satomi Mizukami-Murata, Y. Murata, H. Iwahashi","doi":"10.11403/JSET.9.87","DOIUrl":"https://doi.org/10.11403/JSET.9.87","url":null,"abstract":"Thorium(Th),an actinoide element, is among the most common naturally-occurring radioactive materials found in the environment. Thorium was used as a radiographic contrast agent(thorotrast)from 1930 to 1955, and many studies on its effects on the human body have been reported. Once thorium is absorbed, the risk of cancer increases due to direct bombardment from alpha-particles with high linear energy transfer during thorium decay. Most of these reports focused on irradiation damage caused by long-term thorium exposure. In contrast, acute thorium toxicity derives more from thorium’s chemical reactivity than its radioactive decay. Here, we report the chemical toxicity of thorium using yeast DNA microarray analysis. Thorium treatment of yeast was found to induce 136 genes. Genes involved in“C-compound and carbohydrate metabolism”,“energy”,“cell rescue, defense and virulence”and“biogenesis of cellular component”were induced significantly by thorium treatment. These genes were further classified into the following processes: oxidative stress(7 genes),glycogen and trehalose metabolism(6 genes),and cell wall damage(10 genes).However, only one gene related to DNA damage was induced. These results indicate that thorium causes cell wall damage and induces oxidative stress, and suggest that in order to overcome oxidative stress, cells promote metabolism of energy reserves in the form of glycogen and trehalose.","PeriodicalId":14585,"journal":{"name":"Japanese journal of environmental toxicology","volume":"17 1","pages":"87-100"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87369875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Terrestrial Biotic Ligand model to predict bioavailability of heavy metals in rhizosphere","authors":"R. Shoji","doi":"10.11403/JSET.9.149","DOIUrl":"https://doi.org/10.11403/JSET.9.149","url":null,"abstract":"Bioavailability of heavy metals in soil is to be considered in order to examine toxic effects on soil organisms. Particularly, metal speciation in soil pore water must be taken into account in order to examine the bioavailability to soil organisms. In the Center for the Study of Metals in the Environment, Department of Civil and Environmental Engineering, University of Delaware, some practical studies have been conducted to examine the bioavailability of metals in soil. In this manuscript, some of the promising studies including Terrestrial Biotic Ligand Model(TBLM)are introduced.","PeriodicalId":14585,"journal":{"name":"Japanese journal of environmental toxicology","volume":"2014 1","pages":"149-156"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86631279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of Tributyltin on ephippia production in Daphnia magna","authors":"Osamu Saika, Yoko Kohayakawa, A. Hara","doi":"10.11403/JSET.9.1","DOIUrl":"https://doi.org/10.11403/JSET.9.1","url":null,"abstract":"","PeriodicalId":14585,"journal":{"name":"Japanese journal of environmental toxicology","volume":"32 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82157684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Population and community level impacts on the freshwater Cladocera","authors":"T. Hanazato","doi":"10.11403/JSET.9.43","DOIUrl":"https://doi.org/10.11403/JSET.9.43","url":null,"abstract":"","PeriodicalId":14585,"journal":{"name":"Japanese journal of environmental toxicology","volume":"31 1","pages":"43-50"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78827613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Ishihara, T. Horio, Y. Kobara, A. Yokoyama, S. Mayama
{"title":"Development of A Growth Inhibition Test Method Using Fresh Water Attached Diatoms","authors":"S. Ishihara, T. Horio, Y. Kobara, A. Yokoyama, S. Mayama","doi":"10.11403/JSET.9.101","DOIUrl":"https://doi.org/10.11403/JSET.9.101","url":null,"abstract":"","PeriodicalId":14585,"journal":{"name":"Japanese journal of environmental toxicology","volume":"7 5 1","pages":"101-113"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90319551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Acute Toxicity of Fenthion, an Organophosphorus Insecticide on Damselfly and Freshwater Shrimp through Fenthion-accumulated Midge Larvae","authors":"S. Hatakeyama, Y. Sugaya, Yutaka Ogamino","doi":"10.11403/JSET.8.13","DOIUrl":"https://doi.org/10.11403/JSET.8.13","url":null,"abstract":"","PeriodicalId":14585,"journal":{"name":"Japanese journal of environmental toxicology","volume":"67 4 1","pages":"13-22"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83433116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recent trends in sediment quality standard and importance of the study on fate and transport of chemicals contaminated in coastal sediments","authors":"Yoshiyuki Nakamura","doi":"10.11403/JSET.8.43","DOIUrl":"https://doi.org/10.11403/JSET.8.43","url":null,"abstract":"","PeriodicalId":14585,"journal":{"name":"Japanese journal of environmental toxicology","volume":"44 1","pages":"43-47"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89262848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Toxicity Evaluation of Chlorate by Bioassay Using Seaweeds","authors":"T. Takami, Ayumi Joh","doi":"10.11403/JSET.8.55","DOIUrl":"https://doi.org/10.11403/JSET.8.55","url":null,"abstract":"","PeriodicalId":14585,"journal":{"name":"Japanese journal of environmental toxicology","volume":"14 1","pages":"55-63"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72650652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Nakayama, Yuko Kurokawa, E. Kawahara, Naoko Kitayoshi, H. Harino, T. Miyadai, T. Seikai, S. Kawai
{"title":"The immunotoxic effects of tributyltin on non-specific biodefense system in rainbow trout (Oncorhynchus mykiss)","authors":"A. Nakayama, Yuko Kurokawa, E. Kawahara, Naoko Kitayoshi, H. Harino, T. Miyadai, T. Seikai, S. Kawai","doi":"10.11403/JSET.8.23","DOIUrl":"https://doi.org/10.11403/JSET.8.23","url":null,"abstract":"","PeriodicalId":14585,"journal":{"name":"Japanese journal of environmental toxicology","volume":"245 1","pages":"23-35"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73549526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}