{"title":"Nanosecond vs Microsecond PFA: Can Shorter Pulses Eliminate General Anesthesia?","authors":"Craig C Morris, Babak Nazer","doi":"10.1016/j.jacep.2025.02.030","DOIUrl":"https://doi.org/10.1016/j.jacep.2025.02.030","url":null,"abstract":"","PeriodicalId":14573,"journal":{"name":"JACC. Clinical electrophysiology","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2025-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Outcomes and Electrophysiological Characteristics of Partial Perforation After Left Bundle Branch Area Pacing.","authors":"Hiroyuki Kato, Satoshi Yanagisawa, Yuuki Shimizu, Ryusuke Ota, Taku Sakurai, Kazumasa Suga, Hisashi Murakami, Kenji Kada, Naoya Tsuboi, Yasuya Inden, Toyoaki Murohara","doi":"10.1016/j.jacep.2025.01.016","DOIUrl":"https://doi.org/10.1016/j.jacep.2025.01.016","url":null,"abstract":"<p><strong>Background: </strong>Septal perforation, defined as partial or complete protrusion of a lead helix, is a potential complication of left bundle branch area pacing, theoretically increasing risks of pacing failure and thromboembolism. However, no studies have examined the long-term prognosis of patients with partial perforations (PPs).</p><p><strong>Objectives: </strong>This study aimed to elucidate the incidence, outcomes, and electrophysiological characteristics of PP in clinical and experimental swine studies.</p><p><strong>Methods: </strong>Patients requiring pacing who underwent successful left bundle branch area pacing were retrospectively included. PP was identified using postoperative echocardiography. Clinical outcomes, including all-cause mortality, thromboembolism, and lead-related complications, were compared between the PP and non-PP groups. Waveforms from the nonfiltered unipolar electrogram (NF-EGM) recorded at the lead tip were evaluated to identify morphology specific to PP.</p><p><strong>Results: </strong>Of the 95 patients, PP was confirmed in 25 (26.3%), occurring only in patients with left bundle branch capture, with an incidence rate of 41.7%. Event-free survival rates were comparable between the PP and non-PP groups at a median follow-up of 24 months (log rank, P = 0.298). No thromboembolisms or lead-related complications occurred in the PP group. The type-QS and type-R morphologies of NF-EGM reliably identified and excluded PP, respectively, as validated in swine heart experiments.</p><p><strong>Conclusions: </strong>This study found that PP is not associated with an increased risk of adverse clinical outcomes. Deep septal lead deployment utilizing the NF-EGM morphology would be useful in recognizing and avoiding PP intraoperatively.</p>","PeriodicalId":14573,"journal":{"name":"JACC. Clinical electrophysiology","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shohei Kataoka, Ellie J Coromilas, Chun Hwang, Duy T Nguyen, Jason T Jacobson, Sei Iwai, Melvin M Scheinman
{"title":"Varied Successful Ablation Sites of Nodoventricular/Nodofascicular Pathway-Mediated Tachycardias.","authors":"Shohei Kataoka, Ellie J Coromilas, Chun Hwang, Duy T Nguyen, Jason T Jacobson, Sei Iwai, Melvin M Scheinman","doi":"10.1016/j.jacep.2025.02.027","DOIUrl":"https://doi.org/10.1016/j.jacep.2025.02.027","url":null,"abstract":"","PeriodicalId":14573,"journal":{"name":"JACC. Clinical electrophysiology","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Circumflex Artery Spasm After Cardioversion With a Decapolar Catheter at the Distal Coronary Sinus.","authors":"Emir Baskovski, Omer Akyurek, Timucin Altin","doi":"10.1016/j.jacep.2025.02.019","DOIUrl":"https://doi.org/10.1016/j.jacep.2025.02.019","url":null,"abstract":"","PeriodicalId":14573,"journal":{"name":"JACC. Clinical electrophysiology","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giovanni Peretto, Cristina Basso, Antonio Esposito, Lorenzo Dagna, Paolo Della Bella
{"title":"The \"Cool Down, Then Ablate\" Principle Guides the Treatment of Ventricular Tachycardias in Myocarditis.","authors":"Giovanni Peretto, Cristina Basso, Antonio Esposito, Lorenzo Dagna, Paolo Della Bella","doi":"10.1016/j.jacep.2025.02.010","DOIUrl":"https://doi.org/10.1016/j.jacep.2025.02.010","url":null,"abstract":"","PeriodicalId":14573,"journal":{"name":"JACC. Clinical electrophysiology","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Atrial Fibrillation Ablation Strategies in Heart Failure Patients: Less Can Be Enough!","authors":"Vanessa Sciacca, Philipp Sommer","doi":"10.1016/j.jacep.2025.02.009","DOIUrl":"https://doi.org/10.1016/j.jacep.2025.02.009","url":null,"abstract":"","PeriodicalId":14573,"journal":{"name":"JACC. Clinical electrophysiology","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marshall Winner, Raul Weiss, Jose Osorio, Devi Nair, Luis Aguinaga, Amin Al-Ahmad, Gery Tomassoni, Rohit Mehta, Ammar M Killu, Emile G Daoud
{"title":"High-Power/Short-Duration Ablation Does Not Reduce Incidence or Severity of Esophageal Lesions.","authors":"Marshall Winner, Raul Weiss, Jose Osorio, Devi Nair, Luis Aguinaga, Amin Al-Ahmad, Gery Tomassoni, Rohit Mehta, Ammar M Killu, Emile G Daoud","doi":"10.1016/j.jacep.2025.02.020","DOIUrl":"https://doi.org/10.1016/j.jacep.2025.02.020","url":null,"abstract":"","PeriodicalId":14573,"journal":{"name":"JACC. Clinical electrophysiology","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143996442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David Schaack, Lukas Urbanek, Stefano Bordignon, Joseph Kheir, Andrea Urbani, Shota Tohoku, Jun Hirokami, Karin Plank, Shaojie Chen, Boris Schmidt, K R Julian Chun
{"title":"The Olive Strategy: Improved Pulmonary Vein Isolation Durability With the Pentaspline Pulsed Field Catheter.","authors":"David Schaack, Lukas Urbanek, Stefano Bordignon, Joseph Kheir, Andrea Urbani, Shota Tohoku, Jun Hirokami, Karin Plank, Shaojie Chen, Boris Schmidt, K R Julian Chun","doi":"10.1016/j.jacep.2025.02.026","DOIUrl":"https://doi.org/10.1016/j.jacep.2025.02.026","url":null,"abstract":"<p><strong>Background: </strong>The pentaspline pulsed field ablation (PFA) catheter is rapidly gaining popularity as a tool for pulmonary vein isolation (PVI). Its standard ablation protocol recommends applying 8 applications per pulmonary vein (PV) with 2 different catheter configurations: the flower and the basket shape. Using this protocol, the rate of durably isolated PVs during repeat procedures is not superior to that after conventional thermal PVI.</p><p><strong>Objectives: </strong>This study aimed to improve PVI durability with the pentaspline PFA catheter through an extension of the ablation protocol and the introduction of a novel catheter shape.</p><p><strong>Methods: </strong>We added 2 applications in a small olive-shaped catheter configuration, leading to a total of 10 applications per PV. Procedural data, safety data, and remapping data from patients undergoing repeat procedures and clinical outcomes were analyzed.</p><p><strong>Results: </strong>A total of 400 consecutive patients were treated with the new olive strategy. In patients undergoing repeat procedures, PV reconnection was significantly less frequent after PVI with the olive strategy (13.6% [3 of 22 patients]) than after the conventional strategy (45% [36 of 80 patients]; P = 0.007). Procedure-related complications occurred in 11 (2.75%) of 400 patients. Comparison of 100 patients treated with the olive strategy vs 100 propensity score-matched conventional patients found no difference in freedom of arrhythmia at 180 days after the procedure (olive strategy: 86%; conventional strategy: 87.3%; P = 0.75).</p><p><strong>Conclusions: </strong>We report on the initial clinical experience of a novel ablation protocol for PVI with the pentaspline PFA catheter. The Olive Strategy is safe to use and significantly improves PVI durability.</p>","PeriodicalId":14573,"journal":{"name":"JACC. Clinical electrophysiology","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143763898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}