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Izvestiia Akademii nauk SSSR. Seriia biologicheskaia最新文献

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[The development of the pouch-like structures at the angles of the mouth in the ontogeny of the hamster Phodopus campbelli]. [在campbelli仓鼠个体发育过程中，嘴角处袋状结构的发育]。
Izvestiia Akademii nauk SSSR. Seriia biologicheskaia Pub Date : 1992-09-01
V E Sokolov, N I Demina
{"title":"[The development of the pouch-like structures at the angles of the mouth in the ontogeny of the hamster Phodopus campbelli].","authors":"V E Sokolov,&nbsp;N I Demina","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The development of mouth angle sacciform structure was studied in the ontogenesis of hamster Phodopus campbelli. It was found that the true sacciform structure with all components characteristic for adult animals was formed by the 20th day of postnatal development. Histological data have shown than the sacciform structure is formed in ontogenesis as a result of a complex epidermal transformation involving muscular and connective tissues which comprise the external coat. The structure studied is not formed on the basis of sebaceous glands and cannot be assigned to the class of gland as considered before.</p>","PeriodicalId":14529,"journal":{"name":"Izvestiia Akademii nauk SSSR. Seriia biologicheskaia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1992-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12619249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Synthetic bioantioxidants--inhibitors of acetylcholinesterase activity]. [合成生物抗氧化剂——乙酰胆碱酯酶活性抑制剂]。
Izvestiia Akademii nauk SSSR. Seriia biologicheskaia Pub Date : 1992-09-01
F I Braginskaia, O M Zorina, E M Molochkina, G A Nikiforov, E B Burlakova
{"title":"[Synthetic bioantioxidants--inhibitors of acetylcholinesterase activity].","authors":"F I Braginskaia,&nbsp;O M Zorina,&nbsp;E M Molochkina,&nbsp;G A Nikiforov,&nbsp;E B Burlakova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The inhibitory effects of synthetic antioxidants (3-oxypyridine, pyrimidine and hindered phenols) on the enzymic activity of membrane-bound acetylcholinesterase (AChE) was studied. In terms of estimated kinetic characteristics of AChE-reaction (KM, Vmax, KI), the pattern of enzyme inhibition by the hindered phenol compounds was found to be of non-competitive or mixed type depending on the inhibitor structure or on the substrate acetylcholine or acetylthiocholine used. The comparative study of the inhibitory action of water-soluble derivatives of hindered phenols and fatty-soluble ionol made it possible to reveal possible contributions to the inhibition of both direct and mediated (by the membrane microsurroundings) effects on the membrane-bound AChE by the studied synthetic bioantioxidants.</p>","PeriodicalId":14529,"journal":{"name":"Izvestiia Akademii nauk SSSR. Seriia biologicheskaia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1992-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12619247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[3'-->5'-exonucleases of the rat liver and the correction of replication errors]. [3'- >5'-大鼠肝脏外切酶和复制错误的纠正]。
Izvestiia Akademii nauk SSSR. Seriia biologicheskaia Pub Date : 1992-09-01
N V Beliakova, N E Kleĭner, T P Kravetskaia, O K Legina, S N Naryzhnyĭ, F V Perrino, I V Shevelev, V M Krutiakov
{"title":"[3'-->5'-exonucleases of the rat liver and the correction of replication errors].","authors":"N V Beliakova,&nbsp;N E Kleĭner,&nbsp;T P Kravetskaia,&nbsp;O K Legina,&nbsp;S N Naryzhnyĭ,&nbsp;F V Perrino,&nbsp;I V Shevelev,&nbsp;V M Krutiakov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Mammalian nuclear DNA polymerases alpha and beta are lack of the proofreading 3'-->5' exonucleolytic activity. 40 and 50 kDa 3'-->5' exonucleases were isolated from rat liver. The exonucleases were shown to excise mismatched nucleotides from poly[d(A--T)] template 10 and 2 fold faster than matched ones. The addition of either exonuclease to DNA polymerase alpha from rat liver or calf thymus 5-10 times increased the accuracy of reproduction of primed DNA from bacteriophage phi X174 amber 3, values of exonuclease and DNA polymerase activities being approximately equal. The exonuclease activity surpasses the DNA polymerase one by an order of magnitude in chromatin and nuclear membrane. These data, taken together, are indicative of potent proofreading into hepatocytes.</p>","PeriodicalId":14529,"journal":{"name":"Izvestiia Akademii nauk SSSR. Seriia biologicheskaia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1992-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12506532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The bioenergetic aspects of the mechanism of aging]. [衰老机制的生物能量方面]。
Izvestiia Akademii nauk SSSR. Seriia biologicheskaia Pub Date : 1992-07-01
V V Lemeshko
{"title":"[The bioenergetic aspects of the mechanism of aging].","authors":"V V Lemeshko","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":14529,"journal":{"name":"Izvestiia Akademii nauk SSSR. Seriia biologicheskaia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12623002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The effectiveness of ultralow doses and concentrations of biologically active compounds]. [超低剂量和超低浓度生物活性化合物的有效性]。
Izvestiia Akademii nauk SSSR. Seriia biologicheskaia Pub Date : 1992-07-01
I P Ashmarin, T V Lelekova, L Ts Sanzhieva
{"title":"[The effectiveness of ultralow doses and concentrations of biologically active compounds].","authors":"I P Ashmarin,&nbsp;T V Lelekova,&nbsp;L Ts Sanzhieva","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Numerous data of literature are analysed on the biological activity of ultra-low (10(-12)-10(-19) M) concentrations and corresponding doses of same bioregulators. Our own data are presented on the modulation of lymphatic vessel contractility by peptides (thyroliberin, defensin, and tuftsin) in concentrations ranging from 10(-13) to 10(-16) M. Hypothetic mechanisms of these phenomena are discussed.</p>","PeriodicalId":14529,"journal":{"name":"Izvestiia Akademii nauk SSSR. Seriia biologicheskaia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12623051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The impossibility in principle of an appreciable increase in the life expectancy of the human species]. [人类的预期寿命原则上不可能有明显的增长]。
Izvestiia Akademii nauk SSSR. Seriia biologicheskaia Pub Date : 1992-07-01
V M Mikhel'son
{"title":"[The impossibility in principle of an appreciable increase in the life expectancy of the human species].","authors":"V M Mikhel'son","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":14529,"journal":{"name":"Izvestiia Akademii nauk SSSR. Seriia biologicheskaia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12623058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Aging is a result of a shortening of the "differotene" in the telomere due to end under-replication and under-repair of DNA]. [衰老是由于DNA复制不足和修复不足导致端粒中“差异蛋白”缩短的结果]。
Izvestiia Akademii nauk SSSR. Seriia biologicheskaia Pub Date : 1992-07-01
A M Olovnikov
{"title":"[Aging is a result of a shortening of the \"differotene\" in the telomere due to end under-replication and under-repair of DNA].","authors":"A M Olovnikov","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":14529,"journal":{"name":"Izvestiia Akademii nauk SSSR. Seriia biologicheskaia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12623059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Experimental approaches to elucidating the patterns of the aging of the body]. [阐明身体衰老规律的实验方法]。
Izvestiia Akademii nauk SSSR. Seriia biologicheskaia Pub Date : 1992-07-01
V N Nikitin, N A Babenko
{"title":"[Experimental approaches to elucidating the patterns of the aging of the body].","authors":"V N Nikitin,&nbsp;N A Babenko","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":14529,"journal":{"name":"Izvestiia Akademii nauk SSSR. Seriia biologicheskaia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12623057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The adaptational-regulatory theory of age-related development]. 年龄相关发展的适应调节理论。
Izvestiia Akademii nauk SSSR. Seriia biologicheskaia Pub Date : 1992-07-01
V V Frol'kis
{"title":"[The adaptational-regulatory theory of age-related development].","authors":"V V Frol'kis","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":14529,"journal":{"name":"Izvestiia Akademii nauk SSSR. Seriia biologicheskaia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12623055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The systems-related preconditions of aging]. [与系统相关的老化先决条件]。
Izvestiia Akademii nauk SSSR. Seriia biologicheskaia Pub Date : 1992-07-01
V P Voĭtenko, A V Pisaruk
{"title":"[The systems-related preconditions of aging].","authors":"V P Voĭtenko,&nbsp;A V Pisaruk","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":14529,"journal":{"name":"Izvestiia Akademii nauk SSSR. Seriia biologicheskaia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12623054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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