JAMA ophthalmologyPub Date : 2024-12-01DOI: 10.1001/jamaophthalmol.2024.4493
Shreya A Shah, Jared T Sokol, Karen M Wai, Ehsan Rahimy, David Myung, Prithvi Mruthyunjaya, Ravi Parikh
{"title":"Use of Artificial Intelligence-Based Detection of Diabetic Retinopathy in the US.","authors":"Shreya A Shah, Jared T Sokol, Karen M Wai, Ehsan Rahimy, David Myung, Prithvi Mruthyunjaya, Ravi Parikh","doi":"10.1001/jamaophthalmol.2024.4493","DOIUrl":"10.1001/jamaophthalmol.2024.4493","url":null,"abstract":"","PeriodicalId":14518,"journal":{"name":"JAMA ophthalmology","volume":" ","pages":"1171-1173"},"PeriodicalIF":7.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11581731/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA ophthalmologyPub Date : 2024-12-01DOI: 10.1001/jamaophthalmol.2024.4527
Judith C Maro, Richard Platt, Sengwee Toh
{"title":"Considerations Regarding Association of Semaglutide and Nonarteritic Anterior Ischemic Optic Neuropathy.","authors":"Judith C Maro, Richard Platt, Sengwee Toh","doi":"10.1001/jamaophthalmol.2024.4527","DOIUrl":"10.1001/jamaophthalmol.2024.4527","url":null,"abstract":"","PeriodicalId":14518,"journal":{"name":"JAMA ophthalmology","volume":" ","pages":"1176"},"PeriodicalIF":7.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA ophthalmologyPub Date : 2024-12-01DOI: 10.1001/jamaophthalmol.2024.4815
Nicholas A V Beare, Geraint Davies
{"title":"Tuberculosis Uveitis-Consumed by Uncertainty.","authors":"Nicholas A V Beare, Geraint Davies","doi":"10.1001/jamaophthalmol.2024.4815","DOIUrl":"10.1001/jamaophthalmol.2024.4815","url":null,"abstract":"","PeriodicalId":14518,"journal":{"name":"JAMA ophthalmology","volume":" ","pages":"1148-1149"},"PeriodicalIF":7.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA ophthalmologyPub Date : 2024-12-01DOI: 10.1001/jamaophthalmol.2024.4524
Dong Wook Kim, Caroline M Apovian
{"title":"Considerations Regarding Association of Semaglutide and Nonarteritic Anterior Ischemic Optic Neuropathy.","authors":"Dong Wook Kim, Caroline M Apovian","doi":"10.1001/jamaophthalmol.2024.4524","DOIUrl":"10.1001/jamaophthalmol.2024.4524","url":null,"abstract":"","PeriodicalId":14518,"journal":{"name":"JAMA ophthalmology","volume":" ","pages":"1175-1176"},"PeriodicalIF":7.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA ophthalmologyPub Date : 2024-12-01DOI: 10.1001/jamaophthalmol.2024.4801
David W Hutton, Joshua D Stein
{"title":"Holistic Evaluation of the Burden of Eye Disease.","authors":"David W Hutton, Joshua D Stein","doi":"10.1001/jamaophthalmol.2024.4801","DOIUrl":"10.1001/jamaophthalmol.2024.4801","url":null,"abstract":"","PeriodicalId":14518,"journal":{"name":"JAMA ophthalmology","volume":" ","pages":"1130-1131"},"PeriodicalIF":7.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA ophthalmologyPub Date : 2024-12-01DOI: 10.1001/jamaophthalmol.2024.4401
Nabin Paudel, Laura Brady, Petia Stratieva, Orla Galvin, Beverly Lui, Iris Van den Brande, Jean-Pierre Malkowski, Mayvis Rebeira, Simon MacAllister, Tara O'Riordan, Avril Daly
{"title":"Economic Burden of Late-Stage Age-Related Macular Degeneration in Bulgaria, Germany, and the US.","authors":"Nabin Paudel, Laura Brady, Petia Stratieva, Orla Galvin, Beverly Lui, Iris Van den Brande, Jean-Pierre Malkowski, Mayvis Rebeira, Simon MacAllister, Tara O'Riordan, Avril Daly","doi":"10.1001/jamaophthalmol.2024.4401","DOIUrl":"10.1001/jamaophthalmol.2024.4401","url":null,"abstract":"<p><strong>Importance: </strong>Age-related macular degeneration (AMD) is a highly prevalent and debilitating retinal condition that affects more than 200 million people globally, with the severe late-stage forms-neovascular AMD (nAMD) and geographic atrophy (GA)-affecting more than 11 million people globally. However, much is unknown about the economic burden of the disease.</p><p><strong>Objective: </strong>To estimate the economic burden associated with late-stage AMD in Bulgaria, Germany, and the US at the societal level.</p><p><strong>Design, setting, and participants: </strong>This study used the prevalence approach cost-of-illness economic modeling to estimate costs attributable to late-stage AMD. Data on health care resource utilization, well-being, and productivity were obtained via primary data collection. Additional data required for the model were sourced from available published literature. Data were collected from January 2021 to March 2022, and analyzed from April to July 2022. Participants older than 50 years residing in Bulgaria, Germany, and the US who were diagnosed with late-stage AMD (nAMD or any form of GA) in 1 or both eyes and caregivers who care for people diagnosed with late-stage AMD were recruited through ophthalmological clinics in Bulgaria and Germany and via online newsletters and social media in the US.</p><p><strong>Main outcomes and measures: </strong>The main outcomes were direct medical costs (disease-related health care expenditures), indirect medical costs (care support and assistive technology), well-being cost (loss of well-being), and productivity cost (loss in productivity due to the diseases for both patient and caregivers).</p><p><strong>Results: </strong>Of the 128 individuals with late-stage AMD in this study, 80 (62%) were female, and 120 (94%) were aged 60 years or older. Of the 61 caregivers, 43 (70%) were female and 55 (91%) were aged 45 years or older. Estimated per-annum total costs attributable to late-stage AMD were €449.5 million ($512.5 million) in Bulgaria, €7.6 billion ($8.6 billion) in Germany, and €43.2 billion ($49.4 billion) in the US. Across all countries, 10% to 13% of the total cost incurred was attributed to direct medical costs. In Germany and Bulgaria, the biggest contributor to the total economic burden was reduced well-being (67% and 76%, respectively), whereas in the US, loss of productivity (42%) was the biggest contributor.</p><p><strong>Conclusions and relevance: </strong>The findings of this study indicate a substantial burden of late-stage AMD on patients and caregivers in the US, Germany, and Bulgaria. Across the 3 countries, reduced well-being and loss of productivity were relatively large contributors to the total economic burden. Implementing measures to reduce AMD incidence, delay disease progression, and alleviate humanistic burden may help reduce the economic burden of late-stage AMD.</p>","PeriodicalId":14518,"journal":{"name":"JAMA ophthalmology","volume":" ","pages":"1123-1130"},"PeriodicalIF":7.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA ophthalmologyPub Date : 2024-12-01DOI: 10.1001/jamaophthalmol.2024.4859
Ann M Leahey, Amish Shah, Carol L Shields
{"title":"Three vs 6 Cycles of Adjuvant Chemotherapy for Retinoblastoma.","authors":"Ann M Leahey, Amish Shah, Carol L Shields","doi":"10.1001/jamaophthalmol.2024.4859","DOIUrl":"10.1001/jamaophthalmol.2024.4859","url":null,"abstract":"","PeriodicalId":14518,"journal":{"name":"JAMA ophthalmology","volume":" ","pages":"1107-1108"},"PeriodicalIF":7.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA ophthalmologyPub Date : 2024-12-01DOI: 10.1001/jamaophthalmol.2024.4521
Sylvie Feldman-Billard
{"title":"Considerations Regarding Association of Semaglutide and Nonarteritic Anterior Ischemic Optic Neuropathy.","authors":"Sylvie Feldman-Billard","doi":"10.1001/jamaophthalmol.2024.4521","DOIUrl":"10.1001/jamaophthalmol.2024.4521","url":null,"abstract":"","PeriodicalId":14518,"journal":{"name":"JAMA ophthalmology","volume":" ","pages":"1174-1175"},"PeriodicalIF":7.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JAMA ophthalmologyPub Date : 2024-12-01DOI: 10.1001/jamaophthalmol.2024.4533
Qi N Cui
{"title":"Considerations Regarding Association of Semaglutide and Nonarteritic Anterior Ischemic Optic Neuropathy.","authors":"Qi N Cui","doi":"10.1001/jamaophthalmol.2024.4533","DOIUrl":"10.1001/jamaophthalmol.2024.4533","url":null,"abstract":"","PeriodicalId":14518,"journal":{"name":"JAMA ophthalmology","volume":" ","pages":"1177-1178"},"PeriodicalIF":7.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}