Iranian Journal of Radiation Research最新文献

{"title":"Volumetric-modulated arc stereotactic radiotherapy for intramedullary cervical spinal cord metastases: Report of two cases","authors":"Y. Mori, Toshie Mori, K. Adachi, S. Abe, Y. Oshima, A. Takeuchi, Makoto Ito","doi":"10.18869/ACADPUB.IJRR.18.3.599","DOIUrl":"https://doi.org/10.18869/ACADPUB.IJRR.18.3.599","url":null,"abstract":"The treatment results of intensity-modulated stereotactic radiotherapy (IMSRT) by volumetric-modulated arc therapy (VMAT) for intramedullary cervical spinal cord metastases (IMCSCM) in two cases were presented. Case 1: A 76year-old woman showed left-sided motor weakness and left arm pain and dysesthesia due to IMCSCM at C [cervical] 6-7 (located a little to the left laterally) with multiple small brain metastases from thyroid carcinoma. Multiple brain metastases were successfully treated by stereotactic radiosurgery (SRS). In addition, IMCSCM was treated by IM-SRT. Case 2: A 48year-old man presented with asymptomatic IMCSCM at C2 (located a little to the right laterally) after conventional whole brain radiotherapy (WBRT) and multiple sessions of SRS/SRT for multiple brain metastases from lung adenocarcinoma. IMCSCM was treated by IM-SRT. In both cases 39 Gy in 13 fractions (without PTV [planning target volume] margin, D95%=95% dose) was delivered to the IMCSCM (0.3 ml and 0.5 ml in volume respectively) by coplanar 2-full circular arc VMAT. The maximum dose to the tumor was 46.3 Gy in case 1 and 47.1 Gy in case 2. IMCSCM in both cases shrank markedly without adverse effects during the follow-up period of 32 months and 8 months respectively. The symptoms of the extremities in case 1 were subsided completely until the patient’s death at 34 months after SRT from lung metastasis. In case 1 IMCSCM had been thought to be a relatively radioresistant thyroid carcinoma metastasis. In case 2 IMCSCM was near the field of the prior WBRT. However, both tumors were successfully treated without adverse effects by VMAT IM-SRT.","PeriodicalId":14498,"journal":{"name":"Iranian Journal of Radiation Research","volume":"18 1","pages":"599-604"},"PeriodicalIF":0.0,"publicationDate":"2020-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46611600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effective radium content and radon concentrations in coffee samples","authors":"Ammar S. Hameed, A. Hashim, E. J. Mohammed","doi":"10.18869/ACADPUB.IJRR.18.3.461","DOIUrl":"https://doi.org/10.18869/ACADPUB.IJRR.18.3.461","url":null,"abstract":"Background: Many people in Iraq and indeed the world choose to drink coffee on a daily basis; accordingly, we planned to find the radium and uranium concentrations in addition to the Radon emission rate to determine if coffee shows the levels of radioactivity that may affect people’s lives. Material and Methods: A nuclear track detector (CR-39) was used to study the natural radioactivity of ten samples of coffee collected from local Iraqi markets. Results: The effective radium content varied from 0.13 to 0.66 Bq/kg with a mean 0.32 Bq/kg. The mass exhalation rates of radon vary from 0.024 – 0.121/kg .h, with a mean 0.059 Bq/kg .h, while the surface exhalation rates of radon vary from 0.47 – 2.39/ .h, with a mean 1.16 Bq/m. h. Uranium content varied from 0.10 to 0.54 ppm with a mean value of 0.26 ppm. Conclusion: Insofar as health effects are concerned, the results have shown that all the samples were entirely safe.","PeriodicalId":14498,"journal":{"name":"Iranian Journal of Radiation Research","volume":"18 1","pages":"461-466"},"PeriodicalIF":0.0,"publicationDate":"2020-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41793013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in the radiochemical purity of [18-F]FDG radiopharmaceutical according to the amount of ethanol added","authors":"S. Kim, E. Han","doi":"10.18869/ACADPUB.IJRR.18.3.593","DOIUrl":"https://doi.org/10.18869/ACADPUB.IJRR.18.3.593","url":null,"abstract":"","PeriodicalId":14498,"journal":{"name":"Iranian Journal of Radiation Research","volume":"18 1","pages":"593-598"},"PeriodicalIF":0.0,"publicationDate":"2020-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42475654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral cavity cancers treated with superselective intra-arterial chemoradiotherapy with radiation doses less than 60 Gy: implications for dose reduction from a propensity score-matched analysis","authors":"H. Kaizu, M. Hata, K. Mitsudo, Y. Hayashi, E. Ito, M. Sugiura, S. Takano, Y. Mukai, I. Koike, T. Koizumi","doi":"10.18869/ACADPUB.IJRR.18.3.531","DOIUrl":"https://doi.org/10.18869/ACADPUB.IJRR.18.3.531","url":null,"abstract":"Background: The optimal radiation dose for oral cavity cancers treated with retrograde superselective intra-arterial chemoradiotherapy (SIACRT) is unclear. The aim of the present study was to evaluate the treatment outcome and toxicity in patients treated with <60 Gy compared with those treated with ≥60 Gy to provide evidence for determining the optimal dose. Materials and Methods: Between January 2009 and December 2013, 159 oral cavity cancer patients were treated with SIACRT with curative intent at a single institution. One hundred and twenty-nine patients received ≥60 Gy and 30 received <60 Gy. Local control (LC), disease-free survival (DFS), overall survival (OS), and toxicity were compared. Propensity score matching was performed to reduce bias. Results: The median follow-up period was 48 months (range, 2–88 months). LC (<60 Gy vs. ≥60 Gy, 81.5% vs. 86.1% at 3 years, p = 0.534), DFS (68.8% vs. 72.4% at 3 years, p = 0.816), and OS (85.9% vs. 72.3% at 3 years, p = 0.132) were comparable between the two groups. There was also no difference in toxicity. However, the median overall treatment period was significantly shorter in the <60 Gy cohort (39 days vs. 49 days, p < 0.0001). Conclusion: The radiation dose may be reduced to <60 Gy when treating oral cavity cancers with SIACRT.","PeriodicalId":14498,"journal":{"name":"Iranian Journal of Radiation Research","volume":"18 1","pages":"531-538"},"PeriodicalIF":0.0,"publicationDate":"2020-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42566450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of dose grid resolution on the results of patient-specific quality assurance for intensity-modulated radiation therapy and volumetric modulated arc therapy","authors":"M. Chun, Jung In Kim, Dong-Jin Oh, Hong-Gyun Wu, Jung-Bin Park","doi":"10.18869/ACADPUB.IJRR.18.3.521","DOIUrl":"https://doi.org/10.18869/ACADPUB.IJRR.18.3.521","url":null,"abstract":"Background: This study aims to investigate the effect of reference dose calculation grid size (RDCGS) on gamma passing rate (GPR) for patient-specific quality assurance of intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT). Materials and Methods: A total of 20 patients were retrospectively selected. Both IMRT and VMAT plans were generated for each patient. Reference dose distributions for gamma analysis were calculated with RDCGS of 1–5 mm at intervals of 1 mm. Dose distributions were measured using MapCHECK2 and ArcCHECK dosimeters. Both global and local gamma analyses with gamma criteria of 3%/3 mm, 2%/3 mm, 2%/2 mm, and 2%/1 mm were performed with various RDCGS. Results: As the RDCGS increased from 1 mm to 5 mm, the average global GPRs with 2%/2 mm for VMAT with MapCHECK2 and ArcCHECK decreased by 9.3% and 5.9%, respectively. The average local GPRs decreased by 14% and 11.7%, respectively. For IMRT, the global GPRs decreased by 4.8% and 6%, respectively, whereas the local GPRs decreased by 10.5% and 8.6%, respectively. The effect of the RDCGS on the GPRs became larger when performing local gamma analysis as well as when applying small distance-toagreement (DTA). As the RDCGS increased, the average changes in the GPR per mm of DTA change increased regardless of the type of radiotherapy, detector, or gamma analysis. Conclusion: For an accurate verification of the IMRT and VMAT plans, it is recommended that the reference dose distribution must be calculated with the smallest possible RDCGS.","PeriodicalId":14498,"journal":{"name":"Iranian Journal of Radiation Research","volume":"18 1","pages":"521-530"},"PeriodicalIF":0.0,"publicationDate":"2020-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41644343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of level-I, -II and -III dosimetry quality audits for MV-photon beams emitted from medical linear accelerators","authors":"K. Masood, A. Ullah, A. Hussain, Kh. Mahmood, Gregory R. Hart, W. Muhammad","doi":"10.18869/ACADPUB.IJRR.18.3.505","DOIUrl":"https://doi.org/10.18869/ACADPUB.IJRR.18.3.505","url":null,"abstract":"Background: Dosimetry audits have an important role to safely deliver the prescribed radiation dose to the cancerous area. It not only maintains and improve the treatment standards but also identify issues that are potentially harmful to the patients. This article presents the results of a comparative study of beam output measurements of a high-energy photon beam emitted from a medical linear accelerator. Materials and Methods: The measurements were performed by an International Atomic Energy Commission (IAEA) Quality Assurance/Quality Control survey mission (level-I dosimetry), a national Secondary Standard Dosimetry Laboratory (SSDL) experts (level-II dosimetry) and hospital physicists (level-III dosimetry). Glass dosimeters and cylindrical ionization chambers for level I and cylindrical ionization chambers for level-II and -III dosimetry were used in water by following IAEA TRS-398 protocol. Results: The level-I dosimetry results of glass dosimeters and ionization chambers were compared and percent deviations of -0.4 % and 0.3 % were found for 6 and 15 MV-photon beams, respectively. Similarly, level-II and -III dosimetry results with respect to level-I are in good agreement and within the optimum uncertainty level of ±5%. The annual level-II dosimetry quality audits (i.e., from 2010 to 2015) showed that only one dosimetry audit is out of the optimum level set for this study. However, it is within the tolerance level set for level-II quality audit programs (i.e., < ±5%). Conclusion: In conclusion, this article has demonstrated consistent radiotherapy radiation dosimetry results for MV-photons beams. It also showed quantitative information in-line with the currently achieved accuracy and precision of external megavoltage photon beam dosimetry. Furthermore, this study also established a baseline for current routine audits of radiotherapy dosimetry. Studies of this type are essential to appropriately follow the recommendations and procedures of the pertinent dosimetry protocols.","PeriodicalId":14498,"journal":{"name":"Iranian Journal of Radiation Research","volume":"18 1","pages":"505-510"},"PeriodicalIF":0.0,"publicationDate":"2020-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41676503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of various dosimetric parameters using multiple detectors in the cyberknife® robotic radiosurgery system","authors":"M. Manavalan, M. Duraisamy, V. Subramani, H. Godson, G. Krishnan, M. Venkataraman, T. Ganesh","doi":"10.18869/ACADPUB.IJRR.18.3.437","DOIUrl":"https://doi.org/10.18869/ACADPUB.IJRR.18.3.437","url":null,"abstract":"","PeriodicalId":14498,"journal":{"name":"Iranian Journal of Radiation Research","volume":"18 1","pages":"437-447"},"PeriodicalIF":0.0,"publicationDate":"2020-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49018587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tumor shrinkage evaluation based interfractional cone beam computed tomography for limited disease small-cell lung cancer and relevant impact on dosimetry","authors":"Hui Wang, Hongzhuan Chen, Y. Shao, J. Wang, J. Guo, X. Cai, X. Fu, Zhiyong Xu","doi":"10.18869/ACADPUB.IJRR.18.3.467","DOIUrl":"https://doi.org/10.18869/ACADPUB.IJRR.18.3.467","url":null,"abstract":"","PeriodicalId":14498,"journal":{"name":"Iranian Journal of Radiation Research","volume":"18 1","pages":"457-475"},"PeriodicalIF":0.0,"publicationDate":"2020-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48694871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of patient dose in routine digital radiography in Iran","authors":"B. Mohsenzadeh, M. Deevband, R. Paydar, M. Ghorbani","doi":"10.18869/ACADPUB.IJRR.18.3.449","DOIUrl":"https://doi.org/10.18869/ACADPUB.IJRR.18.3.449","url":null,"abstract":"Background: The present study aimed to investigate patient dose in common X-ray examinations to estimate effective dose in the digital radiography in Iran. Materials and Methods: Entrance surface dose (ESD) was measured based on applied exposure parameters for the common actual examination; and then effective dose (ED) was calculated by use of PCXMC software. The study was conducted on 15358 patients in 85 X-ray rooms; and the necessary data was collected for five age groups, 0-1 year, 1-5 years, 5-10 years, 10-15 years old and adults in each projection. Results: The ranges of ESD and ED in different examinations for all the age groups are 0.02-10.20 mGy and 2.42378.96 μSv respectively. Conclusion: The effective dose as criteria can be used to reduce patients' doses. The special considerations such as: adequate training of imaging staff; updating clinical audits; patient dose considerations; implementation of systematic and regular quality assurance and quality control programs in medical imaging departments should be taken into account to optimize radiological practices.","PeriodicalId":14498,"journal":{"name":"Iranian Journal of Radiation Research","volume":"18 1","pages":"449-460"},"PeriodicalIF":0.0,"publicationDate":"2020-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42372760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of different calculation indexes with dose volume histogram parameters for evaluation of radiation treatment plans in gynecologic malignancies","authors":"Aysun Inal, E. Duman, E. Ozkan","doi":"10.18869/ACADPUB.IJRR.18.3.477","DOIUrl":"https://doi.org/10.18869/ACADPUB.IJRR.18.3.477","url":null,"abstract":"Background: We aimed to investigate the accordance of Critical Organ Scoring Index (COSI), Conformity Index (CI) and Normal Tissue Complication Probability (NTCP) parameters with Dose Volume Histograms (DVH) used for evaluation of 3 different pelvic radiotherapy plans. Materials and Methods: Ten gynecologic carcinoma patients who underwent adjuvant radiotherapy were enrolled in this study. Treatment plans were created with conformal treatment planning (3DCRT) and intensity modulated radiation therapy (IMRT) to a total dose of 50.4 Gy in 28 fractions. Initially, volume related dose evaluation was done via DVH. Subsequently, HI, CI, COSI and NTCP for selected normal tissues were calculated for each plan and compared with DVH parameters. Finally, a graphical demonstration was evaluated to see if the results were in accordance with DVH. Results: CI results were statistically significant in favor of IMRT (p<0.001). Rectum V40Gy decreased with 9IMRT compared to 3DCRT and 7IMRT (p=0.013 and p=0.013). V40Gy for bladder was also lower with 9IMRT compared with 3DCRT and 7IMRT (p=0.005 and p=0.012). COSI calculations revealed better small intestine protection in IMRT plans similar with DVH (p=0.005 and p=0.022). Femoral heads were better protected with IMRT plans were better compared to 3DCRT in NTCP calculations (p=0.002). Normal tissue protection was worst with 3DCRT via both DVH and COSI evaluations (p=0.001 and p<0.001 respectively). Conclusion: Using the indexes in this study to decide the most appropriate plan among multiple treatment plans in gynecologic cancer patients will be timesaving and easier in comparison with evaluating the DVH of every alternative plan.","PeriodicalId":14498,"journal":{"name":"Iranian Journal of Radiation Research","volume":"18 1","pages":"477-486"},"PeriodicalIF":0.0,"publicationDate":"2020-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48682873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}