IP International Journal of Ocular Oncology and Oculoplasty最新文献

{"title":"Granular cell tumor: A rare presentation as intraconal orbital space occupying lesion","authors":"Keerthana Athiaman, Malarvizhi Raman, Anuradha Alagusundaram","doi":"10.18231/j.ijooo.2023.017","DOIUrl":"https://doi.org/10.18231/j.ijooo.2023.017","url":null,"abstract":"Granular cell tumor (GCT) is a rare benign soft tissue tumor. They have been reported in several regions of the body but mostly in the skin and subcutaneous tissue of head and neck. It may involve the orbit, periocular skin, lacrimal sac, optic nerve, ciliary body, conjunctiva and caruncle. Here we present a rare case of intraconal GCT in a 45 year old woman who presented with unilateral proptosis. She presented with forward protrusion of right eye for the past 3 months,MRI orbit revealed a well defined T1/T2/FLAIR hypointense lesion in the inferolateral aspect of intraconal compartment of right orbit. Transconjunctival excision of the lesion was done. Histopathological Examination (HPE) and immunohistochemistry confirmed the diagnosis of Granular cell Tumor.","PeriodicalId":14485,"journal":{"name":"IP International Journal of Ocular Oncology and Oculoplasty","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89140106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Burkholderia pseudomallei – The malicious invader causing orbital cellulitis !!!","authors":"I. Karthiga, Veni Sigamani, S. Bhat, Harish Kumar Aravind","doi":"10.18231/j.ijooo.2023.021","DOIUrl":"https://doi.org/10.18231/j.ijooo.2023.021","url":null,"abstract":"This case report represents an unusual presentation of Melioidosis presenting as orbital cellulitis. Orbital cellulitis is an acute infection of the eye, commonly caused by Staphylococcal, Streptococcal species and also by fungi. Here we report a case of a 57 year old male who was a diabetic and hypertensive presented with fever, protrusion of right eyeball with sudden onset of defective vision. On examination right eye visual acuity was light perception with relative afferent pupillary defect. Proptosis, chemosis and total ophthalmoplegia were present. Routine investigation revealed leucocytosis. Conjunctival swab culture was negative whereas blood culture revealed Burkholderia pseudomallei. On further work up ultrasound abdomen showed splenic abscess. Even with effective treatment with IV antibiotics patient didn’t improve and succumbed to this disease. Ocular involvement in melioidosis is rare but can lead to devastating outcomes. This case represents the highly virulent nature of this organism which rarely presents with ocular involvement as primary presentation.","PeriodicalId":14485,"journal":{"name":"IP International Journal of Ocular Oncology and Oculoplasty","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83295094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemic keratoconjunctivitis: An overview","authors":"R. P. Maurya, Aalok Kumar, Kokil Tiwari","doi":"10.18231/j.ijooo.2023.012","DOIUrl":"https://doi.org/10.18231/j.ijooo.2023.012","url":null,"abstract":"","PeriodicalId":14485,"journal":{"name":"IP International Journal of Ocular Oncology and Oculoplasty","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73069104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary atypical rhabdoid orbital tumor: An entity with aggressive behavior","authors":"Hajar Hanguir, I. Gouzi, A. Akammar, A. Bennis, F. Chraibi, M. Abdellaoui, I. Andaloussi, A. Amarti","doi":"10.18231/j.ijooo.2023.020","DOIUrl":"https://doi.org/10.18231/j.ijooo.2023.020","url":null,"abstract":"Malignant rhabdoid tumors are rare, poorly differentiated tumors which usually affect children under the age of three. These tumors have a predilection for the kidney, central nervous system and soft tissue. The definition classically relies on a characteristic morphology and the inactivation of the hSNF5/INI1 tumor suppressor gene. The diagnosis is based on radiological explorations, as well as anatomopathological and immuno-histochemical studies.Whatever the location of the tumor, the therapeutic protocol is only decided after multidisciplinary consultation meeting, while resorting to a triad of chemotherapy, surgery and radiotherapy. The prognosis remains poor and the survival rate is below 30%. We report a rare case of retro-orbital malignant rhabdoid tumor of a new born girl.","PeriodicalId":14485,"journal":{"name":"IP International Journal of Ocular Oncology and Oculoplasty","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74667760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A clinical study to analyse the effect of treatment on visual outcomes in bilateral refractive myopic amblyopia in pediatric population","authors":"Rinaz Khan, R. Sisodiya","doi":"10.18231/j.ijooo.2023.014","DOIUrl":"https://doi.org/10.18231/j.ijooo.2023.014","url":null,"abstract":"To determine the efficacy of treatment on visual outcomes in bilateral refractive myopic amblyopia according to the degree of amblyopia and myopia in children of 4-18 years of age-group.This prospective interventional study enrolled 25 cases with bilateral myopia in the age group of 4-18yrs excluding those with organic cause. Thorough ocular examination carried out including subjective test, torch-light and slit-lamp examination, fundoscopy, cycloplegic refraction, wet retinoscopy,. Myopia not improving with best-corrected visual acuity[BCVA] selected and classified according to the degree of amblyopia. The Initial and final BCVA compared converted to log MAR scale for statistical analysis. Treatment planned according to degree of amblyopia and myopia were macular stimulation, occlusion, and combination of occlusion with macular stimulation and spectacle correction. Follow-up period was 1 year with initial weekly visits followed by monthly visits. Percentage improvement of visual acuity assessed in each patient.Among 25 cases, with respect to difference in amblyopia grade in BE, maximum mild amblyopia in 10 eyes improved with macular stimulation and 8 eyes of moderate-severe amblyopia improved with combination of macular stimulation and occlusion. P-value[0.01] is statistically significant with macular stimulation in LE.Untreated refractive errors in myopic are more prone to develop bilateral amblyopia. Timely proper treatment and compliance are necessary for visual improvement.","PeriodicalId":14485,"journal":{"name":"IP International Journal of Ocular Oncology and Oculoplasty","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88097769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent updates on the management of ocular sebaceous gland carcinoma","authors":"R. P. Maurya, Sneha Gupta, S. Kadir, Murtuza Nuruddin, Aalok Kumar, M. Prajapat, V. Singh, Gaurav K Pande, Swati Gautam, Varshika Panday","doi":"10.18231/j.ijooo.2023.013","DOIUrl":"https://doi.org/10.18231/j.ijooo.2023.013","url":null,"abstract":"Ocular sebaceous gland carcinoma (SGC) is a relatively rare, slow growing, but most aggressive and life-threatening tumor. It accounts for around 1% of all cutaneous malignancies. In Caucasians, SGCs are rare accounting for 1-5.5% of eyelid malignancies with a high incidence rate (28-60%) reported in the Asian population. In most SGCs no obvious etiology has been identified but few cases are associated with Muir-Torre syndrome. The dysregulation of several cell signaling pathways has been reported in tumorigenesis of SGC. Recently genome sequencing of periocular SGC revealed several gene mutations like TP53 and RB1 genes. Ocular SGC is known as the ‘great masquerader’ as it mimics several benign and inflammatory conditions like chalazion and chronic blepharitis/ blepharoconjunctivitis which may be responsible for delayed diagnosis and high mortality. Clinico-pathologically ocular SGC can be broadly categorized into nodular and pagetoid subtypes. The latter is more aggressive and associated with a high rate of lymph node metastasis and recurrence hence requiring aggressive multimodal treatment. More aggressive features associated with poor prognosis include involvement of both eyelids, infiltrative growth pattern, multicentric in origin with a pattern of spread to surrounding structures like pagetoid spread, vascular, lymphatic and orbital invasion. Although wide surgical excision with tumor-free margin is the gold standard treatment for the localized nodular type of ocular SGC, but the management of advanced-stage disease, invasive or aggressive lesions and recurrence is challenging and often needs a multidisciplinary approach that can reduce the mortality rate in patients with SGC. In this review article, we report recent research in molecular pathogenesis, clinicopathological features, the importance of TNM staging, sentinel lymph node biopsy, map biopsy and immunohistochemical evaluation of tumor markers like p,Ki-67, bcl-1, and p. We also emphasized the treatment of ocular SGC, i.e. surgical excision & reconstruction, topical therapy, neoadjuvant chemotherapy, targeted therapy, and radiation therapy.","PeriodicalId":14485,"journal":{"name":"IP International Journal of Ocular Oncology and Oculoplasty","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91276546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vascular occlusion in a patient with posteriorly dislocated double IOL","authors":"Kanav Gupta, Kritika, B. K. Gupta, Vimal Vashistha","doi":"10.18231/j.ijooo.2023.023","DOIUrl":"https://doi.org/10.18231/j.ijooo.2023.023","url":null,"abstract":"Age and uncontrolled hypertension are well established risk factors for retinal vascular occlusion. IOL (intraocular lens) implantation following intraoperative posterior capsule rupture has an increased risk of IOL dislocation in the posterior segment. We came across a case of infero-temporal branched retinal vein occlusion followed by a direct injury by a mobile IOL which was posteriorly dislocated. The patient also had one another posteriorly dislocated IOL which was stuck in the anterior vitreous. This case highlights the need for the urgent removal of a posteriorly dislocated mobile IOL, which should precede the placement of a secondary IOL to avoid ocular complications.\u0000 \u0000","PeriodicalId":14485,"journal":{"name":"IP International Journal of Ocular Oncology and Oculoplasty","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89645187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pheochromocytoma “the great masquerader” presenting as hypertensive retinopathy: A case report","authors":"Sangeeta Agrawal, R. Agrawal, A. Tripathi","doi":"10.18231/j.ijooo.2023.022","DOIUrl":"https://doi.org/10.18231/j.ijooo.2023.022","url":null,"abstract":"At first glance, the ophthalmologist might seem to be invading a medical territory, not in their domain, when they write of Pheochromocytoma, but this is not true. Pheochromocytoma is an uncommon tumor that develops in chromaffin cells of the paraganglia or adrenal medulla which can give rise to malignant hypertension (systolic >200 mg Hg & diastolic >140). Pheochromocytoma-induced hypertension may present with many physical symptoms and signs, although sometimes the ocular features are the only clues that are present. Clinical suspicion of secondary hypertension should always be considered when fundus examination shows hypertensive retinopathy changes in a younger age group (18 years in our case). The patient, in our case, developed hypertensive retinopathy with macular star development due to Pheochromocytoma. It stresses the significance of a thorough search for a secondary cause of hypertension in young patients.","PeriodicalId":14485,"journal":{"name":"IP International Journal of Ocular Oncology and Oculoplasty","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88799849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paediatric painless proptosis-not always benign: A case of adenoid cystic carcinoma of the lacrimal gland in a child treated with globe sparing surgery and proton beam radiation­","authors":"A. K S, Maneksha Velu, Kavya Shetty, Jeyapriya T","doi":"10.18231/j.ijooo.2023.018","DOIUrl":"https://doi.org/10.18231/j.ijooo.2023.018","url":null,"abstract":"Adenoid cystic carcinoma (ACC) of the lacrimal gland is a rare aggressive malignant epithelial neoplasm. This tumor is rarely seen in children and adolescents. There is a paucity of studies describing the optimal treatment and prognosis of adenoid cystic carcinoma in the paediatric age group. Here, we report a case of lacrimal gland ACC in a 11-year-old girl treated with globe-sparing tumor resection and proton beam radiation therapy (PBRT).","PeriodicalId":14485,"journal":{"name":"IP International Journal of Ocular Oncology and Oculoplasty","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75258908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suture and glue-free autologous graft for pterygium surgery","authors":"S. Puttaswamy, S. D. Shetty","doi":"10.18231/j.ijooo.2023.003","DOIUrl":"https://doi.org/10.18231/j.ijooo.2023.003","url":null,"abstract":"Of various techniques of pteryium surgeries to prevent recurrence, conjunctival limbal auto graft has been the most successful adjuvant since the studies have shown the role of limbal stem cell deficiency (LSCD) as pathology of pterygium. The most common method of auto-graft fixation post pterygium excision is suturing; with drawbacks of prolonged operating time and postoperative discomfort. Replacing sutures with tissue adhesives may shorten the operating time, improve postoperative comfort; however, the major concern of the commercial fibrin glue is the cost and the potential risk of transmission of infection.To study, 1. The efficacy and complications of suture free and glue free conjunctival-limbal auto-graft for the management of pterygia, 2. The outcome of surgeries by two different qualified surgeons  Prospective, interventional case study of 108 consecutive cases of pterygia that had excision with conjunctival-limbal auto-grafting without using glue or sutures. The operated eye patched for a day and followed up on day 1, 3 and 7, 6 weeks and 6 months; watched for hemorrhage beneath the graft, graft retraction, chemosis, recurrence or any other complication.  The mean age of the patients was 40.7 years (range, 25 – 68 years) with female preponderance (60.2%) and nasal pterygia in 65.7 %. Not a single graft was dislodged and none had recurrence in the follow up period of 9-20 months. Graft retraction occurred in 7 cases (6.5%) and one patient had sub-graft hemorrhage which lasted for nine days. 76.9% had no discomfort even in immediate post-operative period. The results were comparable among patients of both the surgeons.Suture- and glue-freelimbal conjunctival auto-grafting following pterygium excision is a safe, effective and economical option for the management of both primary and recurrent pterygium. Learning curve is short and consistently similar results possible in different hands.","PeriodicalId":14485,"journal":{"name":"IP International Journal of Ocular Oncology and Oculoplasty","volume":"116 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77267317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}