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İstanbul Journal of Pharmacy最新文献

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A chemometrics-based approach for the determination of thymoquinone from Nigella sativa L. (Black Cumin) seeds of different geographical regions using the HPLC technique 基于化学计量学的方法，利用高效液相色谱技术测定不同地理区域黑小茴香种子中的胸腺醌含量
İstanbul Journal of Pharmacy Pub Date : 2023-12-28 DOI: 10.26650/istanbuljpharm.2023.1181298
S. Isik, A. G. Usman, S. Abba
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引用次数: 0
Pro-inflammatory ‘M1 macrophage’ vs anti-inflammatory ‘Hydrocortisone’ a new approach to wound healing in HaCaT cells 促炎性 "M1 巨噬细胞 "与抗炎性 "氢化可的松 "是 HaCaT 细胞伤口愈合的新方法
İstanbul Journal of Pharmacy Pub Date : 2023-12-28 DOI: 10.26650/istanbuljpharm.2023.1229554
Selin Engür Öztürk
{"title":"Pro-inflammatory ‘M1 macrophage’ vs anti-inflammatory ‘Hydrocortisone’ a new approach to wound healing in HaCaT cells","authors":"Selin Engür Öztürk","doi":"10.26650/istanbuljpharm.2023.1229554","DOIUrl":"https://doi.org/10.26650/istanbuljpharm.2023.1229554","url":null,"abstract":"","PeriodicalId":14484,"journal":{"name":"İstanbul Journal of Pharmacy","volume":"341 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139152156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inhibitory potentials of Moringa oleifera on activities of neuraminidase, xanthine oxidase and adenosine deaminase 油杉对神经氨酸酶、黄嘌呤氧化酶和腺苷脱氨酶活性的抑制潜力
İstanbul Journal of Pharmacy Pub Date : 2023-12-28 DOI: 10.26650/istanbuljpharm.2023.1068742
U. Magaji, Özlem Saçan, R. Yanardağ
{"title":"Inhibitory potentials of Moringa oleifera on activities of neuraminidase, xanthine oxidase and adenosine deaminase","authors":"U. Magaji, Özlem Saçan, R. Yanardağ","doi":"10.26650/istanbuljpharm.2023.1068742","DOIUrl":"https://doi.org/10.26650/istanbuljpharm.2023.1068742","url":null,"abstract":"","PeriodicalId":14484,"journal":{"name":"İstanbul Journal of Pharmacy","volume":"345 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139148967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ameliorative effect of cranberry on erectile function in diabetic rats 蔓越莓对糖尿病大鼠勃起功能的改善作用
İstanbul Journal of Pharmacy Pub Date : 2023-12-28 DOI: 10.26650/istanbuljpharm.2023.1167417
Didem Yilmaz Oral, Alev Önder, Serap Gür
{"title":"Ameliorative effect of cranberry on erectile function in diabetic rats","authors":"Didem Yilmaz Oral, Alev Önder, Serap Gür","doi":"10.26650/istanbuljpharm.2023.1167417","DOIUrl":"https://doi.org/10.26650/istanbuljpharm.2023.1167417","url":null,"abstract":"","PeriodicalId":14484,"journal":{"name":"İstanbul Journal of Pharmacy","volume":"27 37","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139148251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Virtual drug screening for p65/rela subunit of nf-κb: Promising repurposable drugs in the treatment of stress-based diseases 针对 nf-κb 的 p65/rela 亚基的虚拟药物筛选：治疗应激性疾病的有望再利用药物
İstanbul Journal of Pharmacy Pub Date : 2023-12-28 DOI: 10.26650/istanbuljpharm.2023.1197571
Hüseyin Portakal
{"title":"Virtual drug screening for p65/rela subunit of nf-κb: Promising repurposable drugs in the treatment of stress-based diseases","authors":"Hüseyin Portakal","doi":"10.26650/istanbuljpharm.2023.1197571","DOIUrl":"https://doi.org/10.26650/istanbuljpharm.2023.1197571","url":null,"abstract":"","PeriodicalId":14484,"journal":{"name":"İstanbul Journal of Pharmacy","volume":"31 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139149987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Attitudes and perceptions of pharmacy students toward pharmacognosy and related competencies of the national core education program in Türkiye 土耳其药学专业学生对国家核心教育计划中的药物认知和相关能力的态度和看法
İstanbul Journal of Pharmacy Pub Date : 2023-12-28 DOI: 10.26650/istanbuljpharm.2023.1363930
Hasan Şahin, İçim Gökkaya, Nurdan Yazici Bektaş
{"title":"Attitudes and perceptions of pharmacy students toward pharmacognosy and related competencies of the national core education program in Türkiye","authors":"Hasan Şahin, İçim Gökkaya, Nurdan Yazici Bektaş","doi":"10.26650/istanbuljpharm.2023.1363930","DOIUrl":"https://doi.org/10.26650/istanbuljpharm.2023.1363930","url":null,"abstract":"","PeriodicalId":14484,"journal":{"name":"İstanbul Journal of Pharmacy","volume":"339 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139152239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of selected steroid hormones in sea of Marmara sediment samples by LC-ESI/MS-MS 利用 LC-ESI/MS-MS 分析马尔马拉海沉积物样本中的部分类固醇激素
İstanbul Journal of Pharmacy Pub Date : 2023-12-28 DOI: 10.26650/istanbuljpharm.2023.1277041
Esra Aysel, Türkan Yurdun
{"title":"Analysis of selected steroid hormones in sea of Marmara sediment samples by LC-ESI/MS-MS","authors":"Esra Aysel, Türkan Yurdun","doi":"10.26650/istanbuljpharm.2023.1277041","DOIUrl":"https://doi.org/10.26650/istanbuljpharm.2023.1277041","url":null,"abstract":"","PeriodicalId":14484,"journal":{"name":"İstanbul Journal of Pharmacy","volume":"300 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139152462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Taxonomic significance of anatomy and achene micromorphology of selected Cousinia Cass. species (Asteraceae) Cousinia Cass.（菊科）部分品种的解剖学和瘦果微形态的分类意义
İstanbul Journal of Pharmacy Pub Date : 2023-12-28 DOI: 10.26650/istanbuljpharm.2023.1268289
Deniz Ulukuș, O. Tugay
{"title":"Taxonomic significance of anatomy and achene micromorphology of selected Cousinia Cass. species (Asteraceae)","authors":"Deniz Ulukuș, O. Tugay","doi":"10.26650/istanbuljpharm.2023.1268289","DOIUrl":"https://doi.org/10.26650/istanbuljpharm.2023.1268289","url":null,"abstract":"","PeriodicalId":14484,"journal":{"name":"İstanbul Journal of Pharmacy","volume":"15 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139151655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The investigation of drug repurposing for HDAC1 inhibitory effects by in silico and in vitro methods 通过硅学和体外方法研究 HDAC1 抑制作用的药物再利用
İstanbul Journal of Pharmacy Pub Date : 2023-11-28 DOI: 10.26650/istanbuljpharm.2023.1269175
Hüseyin İstanbullu, Ezgi Turunc, Sami Hamdoun, Merve Saylam, H. Koyu, Tijen Kaya Temiz
{"title":"The investigation of drug repurposing for HDAC1 inhibitory effects by in silico and in vitro methods","authors":"Hüseyin İstanbullu, Ezgi Turunc, Sami Hamdoun, Merve Saylam, H. Koyu, Tijen Kaya Temiz","doi":"10.26650/istanbuljpharm.2023.1269175","DOIUrl":"https://doi.org/10.26650/istanbuljpharm.2023.1269175","url":null,"abstract":"","PeriodicalId":14484,"journal":{"name":"İstanbul Journal of Pharmacy","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139218954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of Antioxidant and Cytotoxic Activities of Opuntia ficus-indica (L.) Mill. Fruit extract 无花果树的抗氧化和细胞毒活性研究轧机。水果中提取
İstanbul Journal of Pharmacy Pub Date : 2019-12-01 DOI: 10.26650/istanbuljpharm.2019.19035
M. E. Okur, N. Karakaş, A. Karadaǧ, Damla Uludağ, D. Polat
{"title":"Investigation of Antioxidant and Cytotoxic Activities of Opuntia ficus-indica (L.) Mill. Fruit extract","authors":"M. E. Okur, N. Karakaş, A. Karadaǧ, Damla Uludağ, D. Polat","doi":"10.26650/istanbuljpharm.2019.19035","DOIUrl":"https://doi.org/10.26650/istanbuljpharm.2019.19035","url":null,"abstract":"DOI : 10.26650/IstanbulJPharm.2019.19035 Opuntia ficus-indica fruits are claimed to possess several health-beneficial properties. This study was carried out to determine the phytochemicals as well as to compare antioxidant activity and cell viability of the methanol extract of OFI-fruits. Antioxidant activity was evaluated by various in vitro tests such as DPPH, ABTS. Furthermore LC-MS and HPLC analysis were performed. The activity of the OFI-fruit extract on viability of U87-MG (glioblastoma multiform), HT-29 (colon cancer) and human primary fibroblast cells has been investigated by determining viable cells on a luciferase based system (Cell TiterGlo; Promega;USA). The results showed that OFI-fruits were source of antioxidant compounds. Moreover, the extract was found to have rich phenolic-flavonoid contents. Quercetin was found in the extract according to LC-MS and HPLC studies. The remarkable increased cell death in the HT-29 and U87 cell lines was detected in a concentration-dependent manner (1-10mg/ml). Among these cell lines, HT-29 responded to OFI-fruit treatment more sensitively to even the lowest dose (1mg/ml). The results of this study showed the OFI-fruit has significant antioxidant capacity and leads to strong cytotoxic activity on various cancer cells. Therefore, it can be suggested that OFI-fruits may have chemo-preventive potential and can be studied further to clarify cytotoxic abilities. You may cite this article as : Okur ME, Karakas N, Karadag AE, Uludag D, Polat DC (2019). Investigation of Antioxidant and Cytotoxic Activities of Opuntia ficus-indica (L.) Mill. Fruit extract. Istanbul J Pharm 10.26650/IstanbulJPharm.2019.19035.","PeriodicalId":14484,"journal":{"name":"İstanbul Journal of Pharmacy","volume":"12 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90538827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
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