International Journal of Virology and AIDS最新文献_第2页

Sexual Health Code Mobile Application to Reduce Transmission of Sexual Diseases 性健康代码移动应用程序，以减少性病的传播

International Journal of Virology and AIDS Pub Date : 2022-01-01 DOI: 10.23937/2469-567x/1510082

Kadir Uludag

引用次数: 0

Antibody Response to SARS-CoV-2 in HIV Patients Co-Infected with COVID-19 HIV合并COVID-19患者对SARS-CoV-2的抗体反应

International Journal of Virology and AIDS Pub Date : 2021-12-31 DOI: 10.23937/2469-567x/1510079

Saha Rumpa, Raizada Alpana, Dewan Pooja, N. Kirti, S. Vikas, Khan Amir Maroof, Mogha Narender Singh, J. Shweta, G. Sunil, Singh Narender Pal

{"title":"Antibody Response to SARS-CoV-2 in HIV Patients Co-Infected with COVID-19","authors":"Saha Rumpa, Raizada Alpana, Dewan Pooja, N. Kirti, S. Vikas, Khan Amir Maroof, Mogha Narender Singh, J. Shweta, G. Sunil, Singh Narender Pal","doi":"10.23937/2469-567x/1510079","DOIUrl":"https://doi.org/10.23937/2469-567x/1510079","url":null,"abstract":"Introduction: As the spike protein of the SARS-CoV-2 envelope has been shown to be highly immunogenic and is the main target for neutralizing antibodies, the present pilot study aimed to evaluate the IgG antibody response to SARS-CoV-2 spike protein in HIV seropositive patients co-infected with COVID 19. Material and methods: This cohort study was carried out in Delhi with HIV seropositive patients infected with COVID -19 whose 6 consecutive blood samples were collected after a gap of every 15 days starting at day 20 post Covid-19 positivity and tested for SARS-CoV-2 anti spike protein IgG antibody by ELISA. Result: Of the 30 patients who were enrolled in this study, in 23.33% specific SARS-CoV-2 spike-binding IgG antibody were not detected in any of their samples. Of the 76.67% patients who had developed COVID-19 IgG antibody, 70% were found to seroconvert at 3 weeks and stability of antibody remained at an average of 65 days post-infection in these patients. Conclusion: The sero-conversion and stability of SARS-CoV-2 anti spike protein IgG antibody in HIV seropositive individuals, who developed COVID-19 infections, are somewhat similar to general population with COVID-19 infections, starting at three weeks post-infection and persisting up to 2-4 months. Seroconversion may not be related to clinical severity of the disease. However 23.33% *","PeriodicalId":14458,"journal":{"name":"International Journal of Virology and AIDS","volume":"73 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86054455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Structural Racism and HIV Risk: Low African American Male to Female Sex Ratio and HIV Diagnosis Rates by State 结构性种族主义和艾滋病毒风险:低非洲裔美国男女性别比例和艾滋病毒诊断率各州

International Journal of Virology and AIDS Pub Date : 2021-10-28 DOI: 10.23937/2469-567x/1510078

Sowah Leonard Anang, Yerkes Brittany

引用次数: 0

A Review on Interventions against COVID-19 2019冠状病毒病防治措施综述

International Journal of Virology and AIDS Pub Date : 2021-09-24 DOI: 10.23937/2469-567x/1510076

Tseha Sintayehu Tsegaye

引用次数: 0

Management and Attitudes of Patients Victims Accidental Exposure to Blood at the Day Care Unit of the Central Hospital of Yaoundé (Cameroon) from January 2007 to December 2016 2007年1月至2016年12月在喀麦隆雅温得中心医院日托病房意外接触血液患者的管理和态度

International Journal of Virology and AIDS Pub Date : 2021-07-26 DOI: 10.21203/rs.3.rs-685953/v1

D. Defo, E. Kouotou, U. Feungue, Joseline Domo, A. N. Ndam, D. Tounouga, E. C. Ndam

{"title":"Management and Attitudes of Patients Victims Accidental Exposure to Blood at the Day Care Unit of the Central Hospital of Yaoundé (Cameroon) from January 2007 to December 2016","authors":"D. Defo, E. Kouotou, U. Feungue, Joseline Domo, A. N. Ndam, D. Tounouga, E. C. Ndam","doi":"10.21203/rs.3.rs-685953/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-685953/v1","url":null,"abstract":"\u0000 Background: There is little data on Accidental Exposure to Blood (AEB) in Cameroon.Objectives: to learn about the management of AEB among professional and non-professional patient at the day care unit of the Central Hospital of YaoundéMethod: This was a 10-year retrospective study in which data concerning socio-demographic characteristics, exposure and consultation circumstances, measures taken after the accident, the status of the source patient and of the patient consultant and the prescribed ARV protocol were analyzed.Results: Six hundred files were selected, including 49.2% professional exposure and 50.2% non-professional. The mean age was 30 ± 9.7 years with extremes of 11 and 67 years. The main circumstances of AEB were needle stick (professional AEB) and rape (non-professional AEB). Prophylaxis with triple antiretroviral therapy has been prescribed to all patients.Conclusion: Non-professional and professional AEB are found in equivalent proportions in our series. Triple antiretroviral therapy was prescribed for all patients. Staff awareness policies could be developed to respect universal precautionary measures.","PeriodicalId":14458,"journal":{"name":"International Journal of Virology and AIDS","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82706193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Subclinical Iron Overload Hampers the Beneficial Effect of Human Pegivirus (Hpgv) On Disease Progression in Human Immunodeficiency Virus Type-1 Infected Blood Donors 亚临床铁超载阻碍人佩吉病毒(Hpgv)对人类免疫缺陷病毒1型感染献血者疾病进展的有益作用

International Journal of Virology and AIDS Pub Date : 2021-03-31 DOI: 10.23937/2469-567X/1510074

Chattopadhyay Debasish, V. Alice, S. Uma, Rai Arvind

{"title":"Subclinical Iron Overload Hampers the Beneficial Effect of Human Pegivirus (Hpgv) On Disease Progression in Human Immunodeficiency Virus Type-1 Infected Blood Donors","authors":"Chattopadhyay Debasish, V. Alice, S. Uma, Rai Arvind","doi":"10.23937/2469-567X/1510074","DOIUrl":"https://doi.org/10.23937/2469-567X/1510074","url":null,"abstract":"Background: Despite frequent association of Human Pegivirus (HPgV) and Torque Teno Virus (TTV) infections with Human Immunodeficiency Virus type-1 (HIV-1) infection, their roles on HIV-1 disease progression remain unclear. Methods: A prospective study on HIV-1 disease progres sion was undertaken in three HIV-1 infected blood donor subgroups at early asymptomatic stages: Those with HPgV co-infections (n = 60), with TTV co-infections (n = 48) and without the two co-infections (n = 54). Within each subgroup, both replacement and voluntary donors are exam -ined. The markers of HIV-1 disease progression included the following virological and immunological parameters: Rate of increase in plasma HIV-1 viral load, rate of fall in CD4+ T lymphocyte count, serum levels of Tumor necrosis factor alpha (TNF-α), TNF-α receptors (TNFRI and TNFRII), and levels of Nuclear Factor kappa beta (NF-kB) in peripheral blood mononuclear cells (PBMCs). Results: In all three HIV-1 infected subgroups, replacement donors displaying biochemical evidence of iron overload had higher levels of disease progression markers at enrollment and lower symptom-free survival duration on follow up compared to voluntary donors in the same subgroup. Vol untary donors in the HPgV co-infected subgroup showed significantly slower rate of HIV-1 disease progression com pared to voluntary donors in the other two subgroups. Re placement donors in the HPgV co-infected subgroup that showed loss HPgV viraemia at 3 years post-enrollment were associated with faster disease progression compared to those showing persistence of HPgV viraemia at the same point. Conclusion: The present study favors the concept that HPgV co-infection slows down disease progression in HIV-1 infected individuals. However, this beneficial effect may be obliterated due to subclinical iron overload, resulting in loss of HPgV vireamia consequent to fall in peripheral CD4+ T lymphocyte count.","PeriodicalId":14458,"journal":{"name":"International Journal of Virology and AIDS","volume":"77 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87450668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influenza A or COVID-19 Reinfection? Making the Right Diagnosis during the COVID-19 Pandemic 甲型流感还是COVID-19再感染?在COVID-19大流行期间做出正确诊断

International Journal of Virology and AIDS Pub Date : 2021-01-16 DOI: 10.23937/2469-567X/1510073

Udochi Njideka, P. Jones, Owusu Melonie

引用次数: 0

Chemotherapy of Potato Virus Y Infecting Potato Plants Using Antiviral Drugs 马铃薯Y病毒感染马铃薯植株的抗病毒药物化疗研究

International Journal of Virology and AIDS Pub Date : 2021-01-15 DOI: 10.3923/ijv.2021.8.19

Mohamed N. Rizk, Y. Shabana, H. Ketta

引用次数: 0

The Transformation of Burnet's Immune Surveillance Cells into Natural Killer Cells and its Circumstances 伯内特免疫监视细胞向自然杀伤细胞的转化及其情况

International Journal of Virology and AIDS Pub Date : 2020-12-31 DOI: 10.23937/2469-567x/1510072

Sinkovics Joseph Geza, Horvath Joseph Csaba

引用次数: 0

Viral Investigation in the Mass Mortality Phenomenon Occurred During Summer Season in Cultured Tilapia Fish 罗非鱼养殖夏季大量死亡现象的病毒调查

International Journal of Virology and AIDS Pub Date : 2020-12-15 DOI: 10.3923/IJV.2021.1.7

A. Ammar, S. Sakr, A. M. A. Waha, A. A. Ahmed, M. M. Eladwey, T. M. Nageeb

引用次数: 0