International Journal of Vascular Medicine最新文献

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Long-Term Follow-Up of Contrast-Induced Acute Kidney Injury: A Study from a Developing Country. 发展中国家造影剂所致急性肾损伤的长期随访研究
IF 1.3
International Journal of Vascular Medicine Pub Date : 2020-12-21 eCollection Date: 2020-01-01 DOI: 10.1155/2020/8864056
Ashraf O Oweis, Sameeha A Alshelleh, Nesreen Saadeh, Mohamad I Jarrah, Rasheed Ibdah, Karem H Alzoubi
{"title":"Long-Term Follow-Up of Contrast-Induced Acute Kidney Injury: A Study from a Developing Country.","authors":"Ashraf O Oweis,&nbsp;Sameeha A Alshelleh,&nbsp;Nesreen Saadeh,&nbsp;Mohamad I Jarrah,&nbsp;Rasheed Ibdah,&nbsp;Karem H Alzoubi","doi":"10.1155/2020/8864056","DOIUrl":"https://doi.org/10.1155/2020/8864056","url":null,"abstract":"<p><strong>Introduction: </strong>Contrast-induced acute kidney injury (CI-AKI) is a worldwide known complication related to the use of contrast media with either imaging or angiography; it carries its own complications and effect on both morbidity and mortality; early identification of patients at risk and addressing modifiable risk factors may help reducing risk for this disease and its complications.</p><p><strong>Methods: </strong>This was a prospective observational study, where all patients admitted for cardiac catheterization between June 2015 and January 2016 were evaluated for CI-AKI. There were two study groups: contrast-induced acute kidney injury (CI-AKI) group, and noncontrast-induced acute kidney injury (non-CI-AKI) group.</p><p><strong>Results: </strong>Patients (<i>n</i> = 202) were included and followed up for 4 years. Death and development of chronic kidney disease (CKD) need for another revascularization were the end points. The incidence of CI-AKI was 14.8%.In univariate analysis, age (<i>P</i> = 0.016) and serum albumin at admission (<i>P</i> = 0.001) were statistically significant predictors of overall death. Age (<i>P</i> = 0.002), HTN (<i>P</i> = 0.002), DM (<i>P</i> = 0.02), and the use of diuretics (<i>P</i> = 0.001) had a statistically significant impact on eGFR. The rate of recatheterization was not statistically significant between the two groups (61 (35.5%) for the non-CI-AKI vs. 12 (40%) for the other group; <i>P</i> = 0.63). Some inflammatory markers (NGAL <i>P</i> = 0.06, IL-19 <i>P</i> = 0.08) and serum albumin at admission <i>P</i> = 0.07 had a trend toward a statistically significant impact on recatheterization. Death (<i>P</i> = 0.66) and need for recatheterization (<i>P</i> = 0.63) were not statistically different between the 2 groups, while the rate of eGFR decline in for the CI-AKI was significant (<i>P</i> = 0.004).</p><p><strong>Conclusion: </strong>CI-AKI is a common complication post percutaneous catheterization (PCI), which may increase the risk for CKD, but not death or the need for recatheterization. Preventive measures must be taken early to decrease the morbidity.</p>","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2020-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769673/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38794612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Corrigendum to "Evaluation of the Correlation between Serum Concentrations of Asymmetric Dimethylarginine and Corrected TIMI Frame Count in Patients with Slow Coronary Flow". “评估冠状动脉血流缓慢患者血清不对称二甲基精氨酸浓度与校正后TIMI框架计数之间的相关性”的勘误表。
IF 1.3
International Journal of Vascular Medicine Pub Date : 2020-12-11 eCollection Date: 2020-01-01 DOI: 10.1155/2020/9796012
Mahshid Naserifar, Mahshid Ataei, Nadia Behzadian, Amir Hooshang Mohammadpour, Mostafa Dastani, Jamal Shamsara, Sepideh Elyasi, Amirhossein Sahebkar, Hesamoddin Hosseinjani
{"title":"Corrigendum to \"Evaluation of the Correlation between Serum Concentrations of Asymmetric Dimethylarginine and Corrected TIMI Frame Count in Patients with Slow Coronary Flow\".","authors":"Mahshid Naserifar,&nbsp;Mahshid Ataei,&nbsp;Nadia Behzadian,&nbsp;Amir Hooshang Mohammadpour,&nbsp;Mostafa Dastani,&nbsp;Jamal Shamsara,&nbsp;Sepideh Elyasi,&nbsp;Amirhossein Sahebkar,&nbsp;Hesamoddin Hosseinjani","doi":"10.1155/2020/9796012","DOIUrl":"https://doi.org/10.1155/2020/9796012","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1155/2020/4592190.].</p>","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2020-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2020/9796012","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38794613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Beneficial Effects of Spirulina Aqueous Extract on Vasodilator Function of Arteries from Hypertensive Rats. 螺旋藻水提取物对高血压大鼠动脉血管扩张功能的有益影响
IF 1.3
International Journal of Vascular Medicine Pub Date : 2020-12-08 eCollection Date: 2020-01-01 DOI: 10.1155/2020/6657077
Diva M Villalpando, Carlos M Verdasco-Martín, Ignacio Plaza, Juan Gómez-Rivas, Fermín R de Bethencourt, Morris Villarroel, José L García, Cristina Otero, Mercedes Ferrer
{"title":"Beneficial Effects of Spirulina Aqueous Extract on Vasodilator Function of Arteries from Hypertensive Rats.","authors":"Diva M Villalpando, Carlos M Verdasco-Martín, Ignacio Plaza, Juan Gómez-Rivas, Fermín R de Bethencourt, Morris Villarroel, José L García, Cristina Otero, Mercedes Ferrer","doi":"10.1155/2020/6657077","DOIUrl":"10.1155/2020/6657077","url":null,"abstract":"<p><p>Hypertension is a multifactorial disorder considered one of the major causes of premature death worldwide. This pathology is associated with vascular functional/structural alterations in which nitric oxide (NO) and oxygen reactive species participate. On the other hand, the use of microalgae extracts in the treatment of cardiovascular diseases is increasing. Based on the antioxidant and antihypertensive properties of Spirulina, this study aims to investigate the effect of an aqueous extract of Spirulina on the vasodilator function of the aorta from spontaneously hypertensive rats (SHR), analyzing the functional role of NO. For this, aortic segments from male SHR were divided into two groups, one control and the other exposed to an Spirulina aqueous extract (0.1% w/v, for 3 hours), to analyze (i) the production of NO, superoxide anion, and hydrogen peroxide; (ii) the vasodilator response induced by acetylcholine (ACh), by the NO donor and sodium nitroprusside (SNP), and by the K<sub>ATP</sub> channel opener and pinacidil; and (iii) the expression of the p-Akt, p-eNOS, and HO-1 proteins. The results showed that the aqueous Spirulina extract (i) increased the production of NO, did not significantly modify that of superoxide, while decreased that of hydrogen peroxide; (ii) increased the vasodilatory responses induced by ACh, NPS, and pinacidil; and (iii) increased the expression of p-Akt and HO-1. These results suggest that incubation with the aqueous Spirulina extract improves the vascular function of arteries from SHR by increasing the release/bioavailability/function of NO. Increased K<sub>ATP</sub> channel activation and expression of pAkt and HO-1 appear to be participating in these actions.</p>","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2020-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787865/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38827875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparing and Correlating Outcomes between Open and Percutaneous Access in Endovascular Aneurysm Repair in Aortic Aneurysms Using a Retrospective Cohort Study Design. 应用回顾性队列研究设计比较经皮与开放入路在主动脉瘤内修复术中的疗效。
IF 1.3
International Journal of Vascular Medicine Pub Date : 2020-11-27 eCollection Date: 2020-01-01 DOI: 10.1155/2020/8823039
Peter DeVito, Ali Kimyaghalam, Sameh Shoukry, Robert DeVito, John Williams, Eashaa Kumar, Eugene Vitvitsky
{"title":"Comparing and Correlating Outcomes between Open and Percutaneous Access in Endovascular Aneurysm Repair in Aortic Aneurysms Using a Retrospective Cohort Study Design.","authors":"Peter DeVito,&nbsp;Ali Kimyaghalam,&nbsp;Sameh Shoukry,&nbsp;Robert DeVito,&nbsp;John Williams,&nbsp;Eashaa Kumar,&nbsp;Eugene Vitvitsky","doi":"10.1155/2020/8823039","DOIUrl":"https://doi.org/10.1155/2020/8823039","url":null,"abstract":"<p><strong>Objective: </strong>This retrospective cohort study is aimed at determining the safety and efficacy between Femoral Open-Cutdown access and Percutaneous access with Endovascular Aneurysm Repair (EVAR) by contrasting perioperative complication rates. We hypothesized that the percutaneous approach is a better alternative for aortic aneurysm patients as it is minimally invasive and has been demonstrated to decrease the length of hospital stay.</p><p><strong>Methods: </strong>We retrospectively reviewed data for patients undergoing EVAR between the years of 2005 and 2013. We then compared overall mortality, hematoma or seroma formation, graft infection, arterio-venous injury, distal embolization, limb loss, myocardial infarction or arrhythmia, and renal dysfunction. Results were demonstrated using a retrospective cohort study design to confirm the hematoma rate associated with EVAR open compared to percutaneous access.</p><p><strong>Results: </strong>Our series involves 73 patients who underwent percutaneous access for EVAR (<i>n</i> = 49) or traditional open cutdown (<i>n</i> = 24). Percutaneous access resulted in significantly less hematoma formation when compared to the traditional open cutdown (4% vs. 12.5%; <i>p</i> < 0.059). Our analysis suggests decreased mortality rates associated with EVAR as compared to the Open-Cutdown method using Northside Medical Center's Study and the OVER Veterans Affairs Cooperative Study (<i>p</i> = 0.0053).</p><p><strong>Conclusion: </strong>Percutaneous access for EVAR is safe and effective when compared to Open-Cutdown access for aortic aneurysm patients. Percutaneous access was associated with decreased rates of in-hospital mortality, hematoma formation, graft infection, and respiratory failure.</p>","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2020-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2020/8823039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38708522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Interesting Scenarios during Radiofrequency Ablation of Varicose Veins at University Hospital of Nepal. 尼泊尔大学医院射频消融术治疗静脉曲张的有趣场景。
IF 1.3
International Journal of Vascular Medicine Pub Date : 2020-11-12 eCollection Date: 2020-01-01 DOI: 10.1155/2020/2035494
S Vaidya, R M Karmacharya, A K Singh, P Thapa
{"title":"Interesting Scenarios during Radiofrequency Ablation of Varicose Veins at University Hospital of Nepal.","authors":"S Vaidya,&nbsp;R M Karmacharya,&nbsp;A K Singh,&nbsp;P Thapa","doi":"10.1155/2020/2035494","DOIUrl":"https://doi.org/10.1155/2020/2035494","url":null,"abstract":"<p><p>A varicose vein is a common venous condition which affects the great saphenous vein and small saphenous vein causing symptoms of pain, edema, itchiness, pigmentation, and ulceration. There are various modalities of the treatment of varicose veins; however, radiofrequency ablation is among the tested and proven treatments for varicose veins. With every case, there can be some unexpected or interesting scenarios which can pose both technical and surgical difficulties. The main objective of this paper is to introduce these scenarios which can occur despite following the standard protocol and methods both preoperatively and intraoperatively. In these scenarios, the surgeon quickly need to decide how to deal with the aberrations. Based on extensive literature and consensus of a team of three vascular surgeons, lists of interesting scenarios were prepared along with their definition. Any occurrences of such scenarios were noted in the operation theatre note. Here, we describe 39 (6.38%) interesting cases among 611 cases of radiofrequency ablation that was performed in Dhulikhel Hospital, Kathmandu University Hospital, from January 2014 until December 2019. Despite following the proper protocol, we can face many unexpected challenges preoperatively, peroperatively, and postoperatively. From this article, we concluded that vigilance of all the factors and proper Doppler ultrasonography can help in identifying most of these scenarios and aid in making proper surgical planning.</p>","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2020-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2020/2035494","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38683909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Evaluation of the Correlation between Serum Concentrations of Asymmetric Dimethylarginine and Corrected TIMI Frame Count in Patients with Slow Coronary Flow. 冠状动脉血流缓慢患者血清不对称二甲基精氨酸浓度与校正后TIMI框架计数的相关性评价。
IF 1.3
International Journal of Vascular Medicine Pub Date : 2020-09-19 eCollection Date: 2020-01-01 DOI: 10.1155/2020/4592190
Mahshid Naserifar, Mahshid Ataei, Nadia Behzadian, Amir Hooshang Mohammadpour, Mostafa Dastani, Amirhossein Sahebkar, Hesamoddin Hosseinjani
{"title":"Evaluation of the Correlation between Serum Concentrations of Asymmetric Dimethylarginine and Corrected TIMI Frame Count in Patients with Slow Coronary Flow.","authors":"Mahshid Naserifar,&nbsp;Mahshid Ataei,&nbsp;Nadia Behzadian,&nbsp;Amir Hooshang Mohammadpour,&nbsp;Mostafa Dastani,&nbsp;Amirhossein Sahebkar,&nbsp;Hesamoddin Hosseinjani","doi":"10.1155/2020/4592190","DOIUrl":"https://doi.org/10.1155/2020/4592190","url":null,"abstract":"<p><p>Coronary slow flow (CSF) is an important angiographic entity that is characterized by delayed opacification of coronary arteries in the absence of epicardial occlusive disease. Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase. Elevated levels of ADMA cause the induction of endothelial dysfunction and thus promote atherosclerosis. This study was aimed at determining the role of ADMA in the development of CSF. One hundred twenty-nine subjects who fulfilled the inclusion criteria were enrolled in this study. According to coronary angiography results, these subjects were divided into five groups. The serum concentration of ADMA was measured in these subjects. In this study, there was no significant correlation between serum concentrations of ADMA and mean corrected TIMI frame count (CTFC) (<i>P</i> > 0.05). However, the ADMA level was significantly correlated with CTFC in the left anterior descending (LAD) coronary artery in patients with CSF (<i>r</i> = -0.381, <i>P</i> = 0.045). Also, plasma ADMA levels were significantly higher in patients with CSF and without CAD compared to patients without CSF and with CAD (50-90%) (<i>P</i> = 0.034). Besides, serum concentrations of ADMA were significantly higher in subjects with BMI < 25 kg/m<sup>2</sup> compared with those having BMI > 30 kg/m<sup>2</sup> (<i>P</i> = 0.003). It was also shown that the levels of ADMA were significantly higher in subjects with age as a cardiovascular risk factor compared with those without this risk factor (<i>P</i> = 0.024). Further studies with larger population sizes are needed to confirm the present findings on the association between the serum concentrations of ADMA and CSF.</p>","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2020-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2020/4592190","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38452351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Three-Dimensional Echocardiography in Evaluating LA Volumes and Functions in Diabetic Normotensive Patients without Symptomatic Cardiovascular Disease. 三维超声心动图评价无症状心血管疾病的糖尿病正常患者的LA容量和功能。
IF 1.3
International Journal of Vascular Medicine Pub Date : 2020-08-19 eCollection Date: 2020-01-01 DOI: 10.1155/2020/5923702
Mohamed Hamza, Ahmed Mamdouh, Dina Ezzeldin, Adnan Tawfik, Ahmed Nayel
{"title":"Three-Dimensional Echocardiography in Evaluating LA Volumes and Functions in Diabetic Normotensive Patients without Symptomatic Cardiovascular Disease.","authors":"Mohamed Hamza,&nbsp;Ahmed Mamdouh,&nbsp;Dina Ezzeldin,&nbsp;Adnan Tawfik,&nbsp;Ahmed Nayel","doi":"10.1155/2020/5923702","DOIUrl":"https://doi.org/10.1155/2020/5923702","url":null,"abstract":"<p><strong>Background: </strong>Cardiovascular complications are the most serious threat to diabetic patients. Associated metabolic and microvascular changes are the main cause of cardiac function affection, and the earliest cardiac change is diastolic dysfunction. Assessment of LA function changes is a key to determine early heart damage of diabetic patients.</p><p><strong>Objectives: </strong>To evaluate the effect of diabetes mellitus on left atrial volumes and functions by using real-time 3-dimensional echocardiography in normotensive patients free from cardiovascular disease.</p><p><strong>Methods: </strong>The study included 110 individuals, 50 controls and 60 patients with diabetes mellitus, 30 patients with type 1 diabetes mellitus and 30 patients with type 2 diabetes mellitus. 2-dimensional echocardiography was used to assess the LA maximum volume and LA phasic volumes, and LA maximum volume indexed to body surface area were measured by 3D echocardiography. LA functions (LA total stroke volume, LA active stroke volume, and LA active emptying fraction) were obtained from RT3D volumetric analysis.</p><p><strong>Results: </strong>The results of the analysis revealed that type 2 diabetes mellitus showed enlarged <i>V</i> <sub>max</sub>, <i>V</i> <sub>min</sub>, and LAVi with an increased LA total stroke volume and decreased active emptying fraction, while type 1 diabetics showed only decreased in active emptying fraction. The LA maximum volume indexed to body surface area (LAVi) was significantly higher in type 2 diabetic patients as compared to normal controls which was 23.55 ± 3.37 ml/m<sup>2</sup> versus 20.30.</p><p><strong>Conclusion: </strong>Patients with type 2 diabetes mellitus have an increased LA volume with impaired compliance and contractility, while patients with type 1 diabetes mellitus have only impaired contractility compared to nondiabetic subjects.</p>","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2020-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2020/5923702","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38376189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Serum Endothelin-1 Correlates with Myocardial Injury and Independently Predicts Adverse Cardiac Events in Non-ST-Elevation Acute Myocardial Infarction. 血清内皮素-1与心肌损伤相关并独立预测非st段抬高急性心肌梗死的不良心脏事件
IF 1.3
International Journal of Vascular Medicine Pub Date : 2020-08-04 eCollection Date: 2020-01-01 DOI: 10.1155/2020/9260812
Anggoro Budi Hartopo, Indah Sukmasari, Ira Puspitawati, Budi Yuli Setianto
{"title":"Serum Endothelin-1 Correlates with Myocardial Injury and Independently Predicts Adverse Cardiac Events in Non-ST-Elevation Acute Myocardial Infarction.","authors":"Anggoro Budi Hartopo,&nbsp;Indah Sukmasari,&nbsp;Ira Puspitawati,&nbsp;Budi Yuli Setianto","doi":"10.1155/2020/9260812","DOIUrl":"https://doi.org/10.1155/2020/9260812","url":null,"abstract":"<p><strong>Introduction: </strong>Serum endothelin-1 is increasingly released in acute myocardial infarction, by necrotic cardiomyocytes. In non-ST-elevation acute myocardial infarction (Non-STEMI), increased serum endothelin-1 on-admission may have clinical significance during acute hospitalisation events.</p><p><strong>Objective: </strong>The purpose of this study is to investigate whether increased serum endothelin-1 level predict adverse cardiac events in patients hospitalized with Non-STEMI.</p><p><strong>Methods: </strong>The design of this research was a prospective cohort study. Consecutive subjects with Non-STEMI undergoing symptom onset ≤24 hour were enrolled and observed during intensive hospitalization. Serum endothelin-1, troponin-I, and hs-C reactive protein were measured from peripheral blood taken on-admission. In-hospital adverse cardiac events were a composite of death, acute heart failure, cardiogenic shock, reinfarction, and resuscitated VT/VF.</p><p><strong>Results: </strong>We enrolled 66 subjects. The incidence of in-hospital adverse cardiac events is 13.6% (10 out of 66 subjects). Serum endothelin-1 level was significantly higher in subjects with in-hospital adverse cardiac events. Subjects with endothelin-1 level >2.59 pg/mL independently predicted adverse cardiac events in hospitalised Non-STEMI patients (adjusted odds ratio 44.43, 95% confidence interval: 1.44-1372.99, <i>p</i> value 0.03). The serum endothelin-1 level was correlated with serum troponin I level (correlation coefficient of 0.413, <i>p</i> value 0.012).</p><p><strong>Conclusion: </strong>Increased serum endothelin-1 on-admission correlated with increased troponin-I and independently predicted in-hospital adverse cardiac events in patients with Non-STEMI.</p>","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2020-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2020/9260812","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38300655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
The Impact of Coexistence of Smoking and Diabetes on the Coronary Artery Severity and Outcomes following Percutaneous Coronary Intervention: Results from the 1ST Jordanian PCI Registry. 吸烟和糖尿病共存对经皮冠状动脉介入治疗后冠状动脉严重程度和结局的影响:来自约旦第一次PCI登记的结果
IF 1.3
International Journal of Vascular Medicine Pub Date : 2020-07-02 eCollection Date: 2020-01-01 DOI: 10.1155/2020/7624158
Mohamad I Jarrah, Said Al-Khatib, Yousef Khader, Hanin N AlKharabsheh, Ayman Hammoudeh, Karem H Alzoubi, Nasr Alrabadi
{"title":"The Impact of Coexistence of Smoking and Diabetes on the Coronary Artery Severity and Outcomes following Percutaneous Coronary Intervention: Results from the 1<sup>ST</sup> Jordanian PCI Registry.","authors":"Mohamad I Jarrah,&nbsp;Said Al-Khatib,&nbsp;Yousef Khader,&nbsp;Hanin N AlKharabsheh,&nbsp;Ayman Hammoudeh,&nbsp;Karem H Alzoubi,&nbsp;Nasr Alrabadi","doi":"10.1155/2020/7624158","DOIUrl":"https://doi.org/10.1155/2020/7624158","url":null,"abstract":"<p><strong>Introduction: </strong>Diabetes mellitus (DM) and smoking are highly prevalent among Middle Eastern patients admitted with acute coronary syndrome (ACS) or who undergo percutaneous coronary intervention (PCI).</p><p><strong>Methods: </strong>This study used the analysis of the data from the first Jordanian PCI registry (JoPCR1) to determine the impact of coexistence of smoking and diabetes mellitus on the coronary artery severity and outcome following percutaneous coronary intervention in Middle Eastern patients.</p><p><strong>Results: </strong>Of 2426 patients enrolled, 1300 (53.6%) and 1055 (43.5%) were diabetics and smokers, respectively. The patients' age was 59.0 ± 10.1 and ranged between 24 and 95 years. Males comprised 79.4% of all patients. The patients were divided into four groups: nondiabetic-nonsmokers (22.2%), diabetic-nonsmokers (34.3%), nondiabetic-smokers (24.2%), and diabetic-smokers (19.2%). Compared with the other three groups, patients in the diabetic-nonsmoker group were older, more likely to be females, and having a higher prevalence of hypertension, dyslipidemia, chronic renal disease, and history of CVD and revascularization. Consequently, the diabetic-nonsmoker patients (but not the diabetic-smokers) had a higher prevalence of multivessel CAD and PCI than the other three groups, highlighting the importance of other risk factors (age, gender, metabolic syndrome, and comorbidities) and not only smoking in predisposing for CAD. Furthermore, those patients had a higher incidence of ACS as an indication for PCI than the stable coronary disease (73% vs 27%) and the highest CRUSADE bleeding risk score (63.9%) among other groups. The in-hospital events including in-stent thrombosis and emergency CABG events did not significantly differ among groups (<i>p</i> = 0.5 and 0.22). Heart failure and major bleeding events occurred significantly higher among diabetic-nonsmokers compared to other groups. In-hospital deaths occurred significantly more among diabetic-nonsmokers. Moreover, the one-month and one-year follow-up outcome events (the mortality rate, in-stent thrombosis, readmission for ACS, coronary revascularization, and major bleedings) occurred more frequently in the diabetic-nonsmoker group. However, the difference was statistically significant only for major bleeding incidences.</p><p><strong>Conclusions: </strong>In this analysis of a completed prospective Middle Eastern PCI registry, the majority of the diabetic-nonsmoker (and not the diabetic-smokers) patients (73%) presented with ACS. This group was the highest at risk for in-hospital PCI complications as well as the worst in outcomes after one year of follow-up. Those patients were more likely to be older, female, and have the worst cardiovascular baseline features, highlighting the importance of other risk factors (age, gender, metabolic syndrome, and comorbidities) and not only smoking in predisposing for CAD. Thus, more sufficient education about controllin","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2020-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2020/7624158","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38178288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Atherosclerotic Extension of Carotid Arteries: An Insertion in Clinical Practice. 颈动脉粥样硬化性延伸:临床实践中的插入。
IF 1.3
International Journal of Vascular Medicine Pub Date : 2020-06-23 eCollection Date: 2020-01-01 DOI: 10.1155/2020/3120327
M L Furlanetto, E F B Chagas, Payão Slm
{"title":"Atherosclerotic Extension of Carotid Arteries: An Insertion in Clinical Practice.","authors":"M L Furlanetto, E F B Chagas, Payão Slm","doi":"10.1155/2020/3120327","DOIUrl":"10.1155/2020/3120327","url":null,"abstract":"<p><strong>Introduction: </strong>Atherosclerotic disease is a diffuse disease that is strongly associated with age, risk factors, and variable progression. The anatomical prevalence of atheromas does not always follow, a sequence by sectors, and in many cases are concomitant.</p><p><strong>Objectives: </strong>This study is aimed at studying atherosclerosis in the arterial territories of the carotid and lower limbs, in order to correlate their extension as a form of primary prevention.</p><p><strong>Methods: </strong>Participating patients with the main risk factors for atherosclerotic disease were composed of two groups: one with chronic peripheral obstructive arterial disease (PAD) and another without PAD. After performing carotid ultrasound Doppler (USD) of all patients, the occasional prevalence of the disease was evaluated. We performed by statistical tests the correlation between the findings in these patients and the risk factors. Obtaining <i>n</i> from 226 patients, in which 116 patients are from the PAD group and 110 patients are from the group without PAD.</p><p><strong>Results: </strong>Our findings add up to 8.8% for lesions over 50% in patients with PAD, with 6.2% over 70% meeting the few published scientific findings. In this study, the correlation was evaluated between carotid stenosis and PAD, in which we observed a positive association. We observed in the studies that the prevalence of moderate and severe carotid stenosis was similar to patients with coronary artery disease (CAD). There are a number of nonclassical risk factors that we do not evaluate, but even studying the traditional ones, we find that they are less than 27% dependent.</p><p><strong>Conclusion: </strong>Therefore, our study proposes an improvement in the clinical approach of patients with PAD for both the carotid and coronary territory, not using only 2 factors traditional risk factors, for the extension study and to consider the PAD that has 10% dependence alone, as effect and projection of the carotid atherosclerotic plaque.</p>","PeriodicalId":14448,"journal":{"name":"International Journal of Vascular Medicine","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2020-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2020/3120327","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38144994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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