Interventional Neuroradiology最新文献

筛选
英文 中文
Trans-Clot MAP gradient: A novel innovative technique during thrombectomy for acute ischemic stroke with potential applications for assessing collateral circulation, determining clot etiology, informing device selection, and predicting first-pass success. 经血栓 MAP 梯度:急性缺血性脑卒中血栓切除术中的一项创新技术,可用于评估侧支循环、确定血栓病因、指导设备选择和预测首次手术成功率。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2026-10-01 Epub Date: 2024-09-27 DOI: 10.1177/15910199241286547
Amit Chaudhari, Mohammad Al Majali, Eugene I Lin, Osama O Zaidat
{"title":"Trans-Clot MAP gradient: A novel innovative technique during thrombectomy for acute ischemic stroke with potential applications for assessing collateral circulation, determining clot etiology, informing device selection, and predicting first-pass success.","authors":"Amit Chaudhari, Mohammad Al Majali, Eugene I Lin, Osama O Zaidat","doi":"10.1177/15910199241286547","DOIUrl":"10.1177/15910199241286547","url":null,"abstract":"<p><p>Endovascular mechanical thrombectomy has significantly improved recovery in acute ischemic stroke (AIS). While traditional patient selection has relied on factors such as last known well and penumbra volume, emerging research highlights the importance of collateral circulation in influencing thrombectomy success. However, current methods to assess collateral circulation are often unreliable and lack standardization, limiting their integration into clinical decision-making and prompting the need for innovative approaches. This study introduces trans-clot manometry as a promising approach for quantitatively assessing collateral blood flow before thrombectomy. Two patients were included in this study: a 64-year-old female with a left M1 near-complete occlusion and an 81-year-old male with a left P1 occlusion. After receiving intravenous tenecteplase, each patient underwent emergent thrombectomy where intraoperative trans-clot manometry revealed significant trans-clot mean arterial pressure (MAP) gradients (66.7% for Patient 1 and 96.9% for Patient 2). Both patients had successful first-pass thrombectomy (Patient 1: TICI 3; Patient 2: TICI 3), with substantial clinical improvement (Patient 1: NIHSS 11 to 1; Patient 2: NIHSS 19 to 8). Intraoperative trans-clot manometry offers a simple yet powerful, objective, and generalizable measure of collateral circulation, applicable to a wide range of AIS cases regardless of clot location or vessel size. In addition, real-time correlations with heart-rate variability and radial artery pressures provide an intrinsic quality control, ensuring proper execution of the technique and accuracy of the resulting MAP gradient. Future research will focus on validating this approach, determining its generalizability, and establishing MAP gradient thresholds to enhance device selection and predict first-pass success.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2868-2873"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intra-arterial thrombolysis after successful endovascular reperfusion for large vessel occlusion stroke: A meta-analysis of randomized seven controlled trials. 血管内再灌注成功后动脉内溶栓治疗大血管闭塞性卒中:一项随机7项对照试验的meta分析。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2026-10-01 Epub Date: 2025-08-13 DOI: 10.1177/15910199251367556
Ali Mortezaei, Nadir Al-Saidi, Yan Lin Li, Vivek S Yedavalli, Robert W Regenhardt, Adam A Dmytriw
{"title":"Intra-arterial thrombolysis after successful endovascular reperfusion for large vessel occlusion stroke: A meta-analysis of randomized seven controlled trials.","authors":"Ali Mortezaei, Nadir Al-Saidi, Yan Lin Li, Vivek S Yedavalli, Robert W Regenhardt, Adam A Dmytriw","doi":"10.1177/15910199251367556","DOIUrl":"10.1177/15910199251367556","url":null,"abstract":"<p><p>BackgroundAlthough thrombectomy is the standard of care for acute ischemic stroke (AIS) due to large-vessel occlusion (LVO), many patients fail to achieve disability-free recovery, highlighting the need for adjunctive therapy to improve outcomes.PurposeThis systematic review and meta-analysis aimed to compare intra-arterial thrombolysis (IAT) and placebo following the successful recanalization of AIS-LVO.Materials and MethodsA systematic literature review of four databases was performed. Categorical and continuous outcomes were calculated using Risk ratios (RRs) and mean differences (MDs) with 95% confidence intervals (CIs), respectively. Any potential heterogeneity was resolved through leave-one-out influence analysis. Risk of bias was assessed using the RoB2 tool. Our study was not registered in PROSPERO. The primary analysis included three published RCTs; four additional trials, including posterior circulation or preliminary data, were incorporated in sensitivity analyses to validate robustness.ResultsA total of three trials with enrolled patients 1187 were included in the study. Four additional trials were also included only for sensitivity analysis. The findings showed that patients who received IAT had a significantly higher rate of 90-day functional excellence (RR = 1.15, 95%CI = 1.01-1.3, <i>P</i> = .032, <i>I</i><sup>2</sup> = 0.0%) than the control group. There was no significant difference between the two groups regarding functional independence, mortality, symptomatic or any intracranial hemorrhage, and total adverse events. There was a significantly higher functional excellence rate in IAT group compared with control group in studies that included patients with expanded thrombolysis in cerebral infarction score (eTICI) score of 2b-3 versus 2c-3 (RR = 1.5, 95%CI = 1.23-1.82 <i>P</i> = .016, <i>I</i><sup>2</sup> = 0.0%) and female patients derived more benefit from IAT than placebo (RR = 1.42, 95%CI = 1.15-1.75, <i>P</i> = .001, <i>I</i><sup>2</sup> = 0.0%). Notably, there was no significant heterogeneity across any primary and secondary outcomes.ConclusionIn patients with AIS-LVO presenting within 24 h of time last seen well who achieved successful endovascular recanalization, IAT significantly improved the likelihood of functional excellence at three months without hemorrhagic risk. Further research is warranted to validate these findings.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2709-2718"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12350307/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144835065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High mechanical thrombectomy procedural volume is not a reliable predictor of improved thrombectomy outcomes in patients with acute ischemic stroke in the United States. 在美国,机械血栓切除术的手术量大并不能可靠地预测急性缺血性中风患者的血栓切除效果。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2026-10-01 Epub Date: 2024-11-06 DOI: 10.1177/15910199241288611
Adnan I Qureshi, Hamza Maqsood, Daniel E Ford, Camilo R Gomez, Daniel F Hanley, Ameer E Hassan, Thanh N Nguyen, Farhan Siddiq, Alejandro M Spiotta, Syed F Zaidi, Chun Shing Kwok
{"title":"High mechanical thrombectomy procedural volume is not a reliable predictor of improved thrombectomy outcomes in patients with acute ischemic stroke in the United States.","authors":"Adnan I Qureshi, Hamza Maqsood, Daniel E Ford, Camilo R Gomez, Daniel F Hanley, Ameer E Hassan, Thanh N Nguyen, Farhan Siddiq, Alejandro M Spiotta, Syed F Zaidi, Chun Shing Kwok","doi":"10.1177/15910199241288611","DOIUrl":"10.1177/15910199241288611","url":null,"abstract":"<p><p>BackgroundThe volume of mechanical thrombectomy (MT) performed at hospitals is used as one of the criteria for advanced-level designation for stroke care.ObjectiveOur study sought to determine the relationship between annual MT procedural volume and in-hospital outcomes in acute ischemic stroke patients undergoing MT in the United States.MethodsWe analyzed the National Inpatient Sample from 2016 to 2020. The hospitals were grouped into quartiles based on the volume of MT procedures performed within the calendar year. We compared the rates of routine discharge/home health care; in-hospital mortality, and post-treatment intracranial hemorrhage (ICH) between the quartiles after adjusting for potential confounders.ResultsPatients undergoing MT ranged from 15,395 in quartile 1 to 78,510 MT in quartile 4. There were lower rates of discharge home/self-care of 22.5%, 20.8%, and 20.8% for quartiles 2, 3, and 4, respectively, compared with 34.9% in quartile 1. The odds of ICH increased to 1.81 (<i>p</i> < 0.001), 1.84 (<i>p</i> < 0.001), and 1.98 (<i>p</i> < 0.001) among the quartiles from lowest to highest procedural volumes. The odds of home discharge/self-care decreased to 0.66 (<i>p</i> < 0.001), 0.60 (<i>p</i> < 0.001), and 0.63 (<i>p</i> < 0.001) among the quartiles from lowest to highest procedural volumes. The odds of in-hospital mortality increased to 1.92 (<i>p</i> < 0.001), 1.99 (<i>p</i> < 0.001), and 1.84 (<i>p</i> < 0.001) among the quartiles from lowest to highest procedural volumes.ConclusionsWe observed a paradoxical relationship between adverse outcomes and the annual procedural volume of MT at the hospital presumably due to the higher severity of acute ischemic stroke treated at high-volume hospitals.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2521-2529"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Arterial spin labeling detects trapped labeled spins in flow-diverted aneurysms and it reflects intra-aneurysmal flow stasis. 动脉自旋标记可检测到血流偏离动脉瘤中的滞留标记自旋体,它反映了动脉瘤内血流瘀滞的情况。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2026-10-01 Epub Date: 2024-09-27 DOI: 10.1177/15910199241286130
Tatsuya Oki, Atsushi Tsuji, Shota Ishida, Jun Matsubayashi, Kazumichi Yoshida, Yoshiyuki Watanabe
{"title":"Arterial spin labeling detects trapped labeled spins in flow-diverted aneurysms and it reflects intra-aneurysmal flow stasis.","authors":"Tatsuya Oki, Atsushi Tsuji, Shota Ishida, Jun Matsubayashi, Kazumichi Yoshida, Yoshiyuki Watanabe","doi":"10.1177/15910199241286130","DOIUrl":"10.1177/15910199241286130","url":null,"abstract":"<p><p>BackgroundThis study evaluated arterial spin labeling (ASL) imaging findings in flow-diverted aneurysms (FD-ANs).MethodsTwenty-one patients with internal carotid artery aneurysms treated with flow-diverter stent (FDS) were included. Time-of-flight magnetic resonance angiography (TOF-MRA) and ASL were performed before and after follow-up digital subtraction angiography (DSA) on the day, 6 months, and/or 1 year after treatment. Two radiologists rated the clarity of the depiction of FD-ANs for MRA on a 3-point scale and the ASL signal intensity of the aneurysm as negative or positive. A neurosurgeon assessed DSA findings using the O'Kelly-Marotta (OKM) grading scale, categorizing them into filling and stasis grades. The 23 examinations were classified according to the OKM grading scale, and the proportion of ASL-positive cases and the proportion of cases with MRA scores of 1-2 (detectable) were calculated for each grade. The relationship between the OKM grading scale and ASL positivity or MRA detectable was examined using Fisher's exact test.ResultsOf seven examinations where the statis grade was 1 or 2, no examinations showed ASL positivity. However, among the 16 examinations in which the stasis grade was 3, 9 examinations showed ASL positivity. A significant association was observed between stasis grade and ASL positivity (<i>p </i>= 0.035). In contrast, no significant relationship was observed between the OKM grading scale and the MRA 3-point scale.ConclusionHigh-signal ASL in FD-ANs could reflect stasis within the aneurysm; therefore, noninvasive ASL can indicate reduction in intra-aneurysmal blood flow after treatment and reperfusion during posttreatment observation.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2423-2430"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559746/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perfusion deficit and vessel wall characteristics to predict recurrent ischemic events in medically treated patients with chronic symptomatic anterior circulation large vessel occlusion. 通过灌注缺陷和血管壁特征预测接受药物治疗的慢性症状性前循环大血管闭塞患者的复发性缺血事件。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2026-10-01 Epub Date: 2024-09-08 DOI: 10.1177/15910199241270653
Chun Zhou, Yue-Zhou Cao, Zhen-Yu Jia, Lin-Bo Zhao, Shan-Shan Lu, Xiao-Quan Xu, Hai-Bin Shi, Sheng Liu
{"title":"Perfusion deficit and vessel wall characteristics to predict recurrent ischemic events in medically treated patients with chronic symptomatic anterior circulation large vessel occlusion.","authors":"Chun Zhou, Yue-Zhou Cao, Zhen-Yu Jia, Lin-Bo Zhao, Shan-Shan Lu, Xiao-Quan Xu, Hai-Bin Shi, Sheng Liu","doi":"10.1177/15910199241270653","DOIUrl":"10.1177/15910199241270653","url":null,"abstract":"<p><p>BackgroundTo investigate the association between perfusion deficit, vessel wall characteristics, and risk of recurrent ischemic events in medically treated patients with chronic symptomatic anterior circulation large vessel occlusion.MethodsWe retrospectively reviewed chronic symptomatic patients due to anterior circulation large vessel occlusion in our center. All patients received multiparametric magnetic resonance imaging (including perfusion-weighted imaging and high-resolution vessel wall imaging) within 4 weeks to 3 months after symptom onset. The association between baseline clinical or imaging variables and recurrent ischemic events was assessed in bivariate models and multivariable logistic regression to identify independent predictors of recurrence.ResultsAmong 71 enrolled patients, 21.1% (15/71) patients had recurrent ischemic events (nine ischemic strokes and six transient ischemic attacks) during a 2-year follow-up. In bivariate models, hypertension, occlusion with hyperintense signals, the presence of intraluminal thrombus, Tmax >4 s volume, Tmax >6 s volume, Tmax >8 s volume, and Tmax >10 s volume were associated with recurrence (all <i>p</i> < 0.05). In multivariate analysis, hypertension (<i>p</i> = 0.039, OR 10.057 (95% CI, 1.123-90.048)), higher deficit volume of Tmax >4 s (<i>p</i> = 0.011, OR 1.012 (95% CI, 1.003-1.021)) and occlusion with hyperintense signal (<i>p</i> = 0.030, OR 6.732 (95% CI, 1.200-37.772)) were still independent predictors of recurrent ischemic events.ConclusionsBesides hypertension history, higher deficit volume of Tmax >4 s and occlusion with hyperintense signal determined using multiparametric MRI are strongly associated with risk for recurrent ischemic events in medically treated patients with chronic symptomatic anterior circulation large vessel occlusion. Future studies are needed to determine the utility of revascularization strategies in such high-risk patients.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2336-2344"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569740/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142153991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The relative cerebral blood volume (rCBV) < 42% is independently associated with hemorrhagic transformation in anterior circulation large vessel occlusion. 相对脑血容量(rCBV) < 42%与前循环大血管闭塞出血转化独立相关。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2026-10-01 Epub Date: 2025-01-06 DOI: 10.1177/15910199241308322
Dhairya A Lakhani, Aneri B Balar, Subtain Ali, Musharaf Khan, Hamza A Salim, Manisha Koneru, Sijin Wen, Richard Wang, Janet Mei, Argye E Hillis, Jeremy J Heit, Gregory W Albers, Adam A Dmytriw, Tobias D Faizy, Max Wintermark, Kambiz Nael, Ansaar T Rai, Vivek S Yedavalli
{"title":"The relative cerebral blood volume (rCBV) < 42% is independently associated with hemorrhagic transformation in anterior circulation large vessel occlusion.","authors":"Dhairya A Lakhani, Aneri B Balar, Subtain Ali, Musharaf Khan, Hamza A Salim, Manisha Koneru, Sijin Wen, Richard Wang, Janet Mei, Argye E Hillis, Jeremy J Heit, Gregory W Albers, Adam A Dmytriw, Tobias D Faizy, Max Wintermark, Kambiz Nael, Ansaar T Rai, Vivek S Yedavalli","doi":"10.1177/15910199241308322","DOIUrl":"10.1177/15910199241308322","url":null,"abstract":"<p><p>BackgroundPretreatment CT perfusion (CTP) marker relative cerebral blood volume (rCBV) < 42% lesion volume has recently shown to predict poor collateral status and poor 90-day functional outcome. However, there is a paucity of studies assessing its association with hemorrhagic transformation (HT). Here, we aim to assess the relationship between rCBV < 42% lesion volume with HT.MethodsIn this retrospective study, we included patients with acute ischemic stroke secondary to large vessel occlusion (AIS-LVO) of anterior circulation who had successful recanalization from two comprehensive stroke centers between 9/1/2017 and 10/01/2023. Successful recanalization was defined as modified treatment in cerebral infarction (mTICI) 2b or greater. Logistic regression analysis and ROC analysis were used to assess the relationship between rCBV <42% and HT.ResultsIn total, 150 patients (median age: 69 years, 58.7% female) met our inclusion criteria. On multivariable logistic regression analysis, taking into account age, sex, hypertension, hyperlipidemia, diabetes, prior stroke or transient ischemic attack, admission National Institute of Health stroke scale (NIHSS), Alberta Stroke Program Early CT Score (ASPECTS), and intravenous thrombolysis, rCBV <34% (aOR:1.01, <i>P</i> < .05), rCBV <38% (aOR:1.01, <i>P</i> < .05) and rCBV <42% (aOR:1.01, <i>P</i> < .05) lesion volumes were independently associated with HT. On ROC analysis rCBV < 42% (AUC = 0.61, <i>P</i> < .05) performed slightly better than rCBV < 38% (AUC = 0.59, <i>P</i> < .05) and rCBV < 34% (AUC = 0.59, <i>P</i> < .05) in predicting HT.ConclusionThe rCBV <42% lesion volume is independently associated with HT in AIS-LVO patients who underwent successful recanalization.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2617-2624"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11705296/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142948459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimizing Tigertriever adjustable stentriever technique: Operators' experience. 优化 Tigertriever 可调式支架刀技术:操作员的经验。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2026-10-01 Epub Date: 2024-09-02 DOI: 10.1177/15910199241272743
Brian Jankowitz, Eitan Abergel, Ronit Agid, Abdul Rahman Al-Schameri, Krzysztof Bartosz Kądziołka, Allan Brook, Michael Diepers, Jeffrey Farkas, Johanna Fifi, Sebastian Fischer, Chirag Gandhi, Reid Gooch, Ramesh Grandhi, Guglielmo Pero, Guy Raphaeli, Sudipta Roychowdhury, Shahram Majidi, Christian Paul Stracke, Nader Sourour, Omar Tanweer, Satoshi Tateshima, Phil Taussky, Martin Wiesmann, Albert Yoo, Daniel W Zumofen, Justin Singer
{"title":"Optimizing Tigertriever adjustable stentriever technique: Operators' experience.","authors":"Brian Jankowitz, Eitan Abergel, Ronit Agid, Abdul Rahman Al-Schameri, Krzysztof Bartosz Kądziołka, Allan Brook, Michael Diepers, Jeffrey Farkas, Johanna Fifi, Sebastian Fischer, Chirag Gandhi, Reid Gooch, Ramesh Grandhi, Guglielmo Pero, Guy Raphaeli, Sudipta Roychowdhury, Shahram Majidi, Christian Paul Stracke, Nader Sourour, Omar Tanweer, Satoshi Tateshima, Phil Taussky, Martin Wiesmann, Albert Yoo, Daniel W Zumofen, Justin Singer","doi":"10.1177/15910199241272743","DOIUrl":"10.1177/15910199241272743","url":null,"abstract":"<p><p>The Tigertriever is a novel, radially adjustable stentriever that addresses limitations in traditional mechanical thrombectomy devices by providing enhanced user control over clot integration. This provides the ability to adapt to patient-specific factors such as varying vessel sizes and clot compositions and may be particularly crucial for ensuring efficacy and safety in distal locations. This consensus paper synthesizes the clinical techniques from a consortium of experienced international operators. It outlines the current data on the Tigertriever, discusses the new operator-controlled capabilities, and provides a recommended approach for both proximal and distal mechanical thrombectomy, emphasizing the \"FLEX\" approach (Fast Controlled Expansion with Relaxation) for optimal integration and reduced clot disruption.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2772-2779"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11573707/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142107419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigator-initiated clinical trial of stabilizer device: A novel intracranial exchange guidewire for neuroendovascular treatments. 由研究者发起的稳定器临床试验:用于神经内血管治疗的新型颅内交换导丝。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2026-10-01 Epub Date: 2024-08-07 DOI: 10.1177/15910199241262851
Chiaki Sakai, Nobuyuki Sakai, Catherine Peterson, Tsuyoshi Ohta, Hidenori Oishi, Toshiyuki Fujinaka, Yuji Matsumaru, Akira Ishii, Hirotoshi Imamura, Shinichi Yoshimura, Takashi Izumi, Tetsu Satow, Yasushi Ito, Kenji Sugiu, Shigeru Miyachi, Teruyuki Hirano, Tatsuo Kagimura, Naoki Kaneko, Satoshi Tateshima
{"title":"Investigator-initiated clinical trial of stabilizer device: A novel intracranial exchange guidewire for neuroendovascular treatments.","authors":"Chiaki Sakai, Nobuyuki Sakai, Catherine Peterson, Tsuyoshi Ohta, Hidenori Oishi, Toshiyuki Fujinaka, Yuji Matsumaru, Akira Ishii, Hirotoshi Imamura, Shinichi Yoshimura, Takashi Izumi, Tetsu Satow, Yasushi Ito, Kenji Sugiu, Shigeru Miyachi, Teruyuki Hirano, Tatsuo Kagimura, Naoki Kaneko, Satoshi Tateshima","doi":"10.1177/15910199241262851","DOIUrl":"10.1177/15910199241262851","url":null,"abstract":"<p><p>BackgroundNeuroendovascular procedures, especially those involving significant vessel tortuosity, giant intracranial aneurysms, or distally located lesions, frequently necessitate exchange methods. However, exchange maneuvers pose a risk of inadvertent vessel injury. To address these challenges, a Stabilizer device was developed and evaluated for its efficacy and safety. This clinical trial aimed to assess the efficacy and safety of the Stabilizer device in facilitating the navigation of neuroendovascular devices to target lesions in cases where the exchange technique was necessary.MethodsThis was a single-arm, prospective, open-label, multicenter clinical trial performed at nine different sites. It focused on investigating the use of the Stabilizer device for treating intracranial aneurysms and atherosclerosis.ResultsA total of 31 patients were enrolled across nine centers in Japan from July 21, 2022, to March 10, 2023. The study enrolled 24 (77.4%) patients with intracranial aneurysms and seven (22.6%) patients with intracranial artery stenosis. Majority of the target lesions were in the middle cerebral artery territory (83.9%). The Stabilizer device was used to exchange for 0.027-inch catheters, intermediate catheters, PTA balloons, and Wingspan stent system. The Stabilizer device demonstrated 100% technical success rate. While three complications related to the treatment were noted, there were no complications related to the device, including any vascular damage.ConclusionsThis is the first multicenter clinical trial that investigated and demonstrated technical efficacy as well as overall safety profile of the Stabilizer device in neuroendovascular procedures where the use of an exchange method was necessary.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2168-2174"},"PeriodicalIF":2.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569718/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141897438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Blazing the trail! Commentary on "Intra-arterial lidocaine administration in middle meningeal artery for short-term treatment of subarachoid hemorrhage-related headaches" by Qureshi et al. 开辟道路!对Qureshi等人“脑膜中动脉内给予利多卡因短期治疗蛛网膜下腔出血相关性头痛”的评论。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2026-08-01 Epub Date: 2025-02-25 DOI: 10.1177/15910199251324039
Alexander Sirakov, Kristian Ninov, Kristina Sirakova, Stanimir Stefanov Sirakov
{"title":"Blazing the trail! Commentary on \"Intra-arterial lidocaine administration in middle meningeal artery for short-term treatment of subarachoid hemorrhage-related headaches\" by Qureshi et al.","authors":"Alexander Sirakov, Kristian Ninov, Kristina Sirakova, Stanimir Stefanov Sirakov","doi":"10.1177/15910199251324039","DOIUrl":"10.1177/15910199251324039","url":null,"abstract":"<p><p>In their recently published INR study, Qureshi et al. present their results on intra-arterial lidocaine administration in the middle meningeal artery for the short-term treatment of subarachnoid hemorrhage (SAH)-related headaches. The authors demonstrate that their proposed intra-arterial treatment consistently alleviates headaches in patients with SAH. The purpose of this commentary is to commend the authors on their paper and the notable results they have achieved. It is always pleasant to encounter studies that not only make it to the \"Latest Online\" section of neurointerventional journals but also push the boundaries, advancing our understanding and care for patients in the most meaningful ways. There is no doubt that our field has witnessed remarkable progress and an expanding spectrum of interventions that endovascular neuroservices can offer. Several therapeutic approaches have emerged from similarly constructive articles, including intra-arterial chemotherapy for malignant cerebral tumors, innovative treatments for cerebrospinal fluid-venous fistulas, hydrocephalus, and chronic subdural hematomas, as well as the implantation of brain-computer interface devices.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"2047-2049"},"PeriodicalIF":2.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863191/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143501312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rescue extracranial vertebral stenting in tandem occlusions: A preliminary Vietnamese study. 串联闭塞时的颅外椎体支架抢救:越南的一项初步研究。
IF 2.1 4区 医学
Interventional Neuroradiology Pub Date : 2026-08-01 Epub Date: 2024-07-21 DOI: 10.1177/15910199241264342
Thang Le Minh, Cuong Tran Chi, Nam Nguyen Hoai, Dinh Nguyen Hoang, Giang Nguyen Luu, Huy Nguyen Dao Nhat, Linh Duong Hoang, Tran Nguyen Tran, Luan Tran Minh Bao
{"title":"Rescue extracranial vertebral stenting in tandem occlusions: A preliminary Vietnamese study.","authors":"Thang Le Minh, Cuong Tran Chi, Nam Nguyen Hoai, Dinh Nguyen Hoang, Giang Nguyen Luu, Huy Nguyen Dao Nhat, Linh Duong Hoang, Tran Nguyen Tran, Luan Tran Minh Bao","doi":"10.1177/15910199241264342","DOIUrl":"10.1177/15910199241264342","url":null,"abstract":"<p><p>Background and PurposeThe acute vertebrobasilar occlusion associated with the poor prognosis, particularly tandem occlusion. However, few data on the efficacy of the endovascular therapy was indicated in this occlusion. We investigated whether the additional rescue extracranial vertebral stenting improved clinical outcome by modified Rankin scale (mRS) score within 3 months after the procedure.MethodsThis was a retrospective analysis of patients with acute posterior tandem occlusion who were treated with rescue extracranial vertebral stenting between December 2020 and January 2024 at our hospital. Clinical, neuroimaging, procedural, and complication data were collected. Primary outcomes included the rate of good outcomes (mRS ≤ 2) at 3-month follow-up.ResultsNine patients who underwent rescue extracranial vertebral stenting in posterior circulation tandem occlusions were enrolled in the study. All patients were achieved the successful recanalization (mTICI ≥ 2b). Of Dotter technique in the \"distal-to-proximal\" approach, Diagnostic-Dotter made up 66.7%. Five patients (55.6%) with good outcome (mRS ≤ 2) at 3 months, and 1 patient (11.1%) underwent suboccipital decompressive craniectomy due to the malignant cerebellar infarction.ConclusionOur study suggests that despite the small series with posterior tandem occlusions, the rescue extracranial vertebral stenting could be an important alternative treatment followed by mechanical thrombectomy.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"1546-1551"},"PeriodicalIF":2.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571124/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141734120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书