{"title":"Fashion consumers' response to the COVID-19 pandemic and today’s future","authors":"Theodore Tarnanidis","doi":"10.30574/ijsra.2024.12.2.1286","DOIUrl":"https://doi.org/10.30574/ijsra.2024.12.2.1286","url":null,"abstract":"This study examines the effects of the pandemic on the consumption of clothing. After referring to some general elements and characteristics of the situation during the period of Covid-19, the issue addressed and the research carried out are then thoroughly analyzed. Consumption and behavior of the consumers during the pandemic in the broadest sense are the first point of analysis. This study makes three major contributions. First, it highlights the history of the future of covid-19 in fashion. Second, it contributes to research within the fashion marketing domain by examining the interface of the distinct sections of socioeconomic changes. Finally, it presents a snapshot of guidelines to direct companies in understanding the future requirements for sustainable fashion, by offering rich implication for marketing managers and academic research in marketing.","PeriodicalId":14366,"journal":{"name":"International Journal of Science and Research Archive","volume":"4 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141795739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Feto-maternal outcome of Rh-Negative pregnancy presenting in a tertiary healthcare centre","authors":"C. Anu Krishna, Kala K, Ramya K","doi":"10.30574/ijsra.2024.12.2.1174","DOIUrl":"https://doi.org/10.30574/ijsra.2024.12.2.1174","url":null,"abstract":"Background: The term \"Rhesus incompatibility\" describes the mismatched Rh types of the mother and the fetus. It is linked to the onset of hemolytic disease of the newborn (HDN) ranging from haemolytic anemia to hydrops fetalis and also related to maternal Rh sensitization. The disease incidence is currently declining globally, having dropped from 1.3%–1.7% in the 1980s to 0.17% in the 1990s1. Erythroblastosis foetalis is one of the most terrible consequences of an ABO incompatible or Rh incompatible pregnancy. About 10% of all Rh-negative pregnancies result in Rh incompatibility in the Rh-negative mother carrying a Rh-positive fetus. Methods: This observational study was carried out among 60 Rh negative pregnant women attending our antenatal clinic and delivered in our institution from October 2022 to March 2024.The Rh negative women were followed up with a series of investigations such as Indirect Coombs Test (ICT), MCA-PSV and with regular antenatal care (ANC). After birth neonates were followed up with blood grouping and Rh typing, direct coombs test (DCT), duration of phototherapy, duration of NICU stay , need for immunoglobulin and exchange transfusion were recorded to evaluate the maternal and neonatal outcomes.The data was collected and tabulated in Microsoft excel sheet and the percentages were calculated. Results: This study included a total of 60 Rh negative mothers ,where 48 (80%) of them were aged less than 30 years and 12 of them (20%) were more than 30 years of age. Antenatally, 51 (85%) women were ICT negative and received RAADP, 9(15%) women were ICT positive and anti D titres were less than 1:16 followed up with MCA-PSV which was normal/less than 1.5MoM. The total preterm births were 6(10%).The total admissions to NICU were 12(20%) in our study. All the 9 babies born to ICT positive mothers turned out to be Direct Coombs test (DCT) positive and were managed with double surface phototherapy. For 2(3.3%) babies, human immunoglobulin was given. Only 1(1.6%) baby required exchange transfusion. Conclusion: We conclude that, severe hyperbilirubinemia and hydrops foetalis, which were observed previously are drastically reduced with recent advances and the use of Routine antenatal Anti D prophylaxis (RAADP). Neonatal morbidity and mortality reduced drastically with newer advances like immunoglobulin reducing the need for exchange transfusion and better NICU care. ICT positivity of 15% despite of postnatal immunisation suggest that there is chances of silent fetomaternal haemorrhage during antenatal period, health care professionals should be more knowledgeble with prenatal screening, the value of blood grouping and Rh typing, anti-D immunisation following sensitising events like MTP, abortion, ectopic pregnancy, ECV and regular implementation of RAADP in clinical practice.","PeriodicalId":14366,"journal":{"name":"International Journal of Science and Research Archive","volume":"12 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141795780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vanisri. M, Sreesivasakthi. A, MuthuKaviya. M, Roja Jayashankar, Salai Dhivyathai. N, Rajaganapathy. K, Srinivasan.R
{"title":"Accelerate drug repurposing with in-silico molecular modelling techniques, tools and databases: A comprehensive review","authors":"Vanisri. M, Sreesivasakthi. A, MuthuKaviya. M, Roja Jayashankar, Salai Dhivyathai. N, Rajaganapathy. K, Srinivasan.R","doi":"10.30574/ijsra.2024.12.2.1197","DOIUrl":"https://doi.org/10.30574/ijsra.2024.12.2.1197","url":null,"abstract":"Exploring innovative ways to accelerate drug repurposing through in-silico molecular modeling techniques, tools, and databases is paramount in modern pharmaceutical research. Exploring the vast landscape of drug repurposing presents both a challenge and an opportunity in the realm of pharmaceutical research. With the escalating costs and time-consuming nature of developing new drugs from scratch, the urgency to identify novel therapeutic uses for existing compounds has never been more pressing. Readers can expect a detailed exploration of how computational methods are revolutionizing drug repurposing efforts, offering insights into accelerated drug discovery and development timelines. This comprehensive review dives deep into the opportunities and challenges of leveraging computational approaches to identify new therapeutic uses for existing drugs and this article highlights the potential of in-silico methods to revolutionize drug discovery by repurposing existing compounds efficiently and cost-effectively, ultimately leading to faster development timelines and improved patient outcomes and will be focused for In-silico molecular modeling techniques, tools, and databases as powerful allies in expediting this crucial process.","PeriodicalId":14366,"journal":{"name":"International Journal of Science and Research Archive","volume":"9 37","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141795796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mangrove flora as an ecotourism attraction in the Perancak Mangrove, Jembrana Bali","authors":"I Ketut Ginantra, I Ketut Muksin, Martin Joni","doi":"10.30574/ijsra.2024.12.2.1251","DOIUrl":"https://doi.org/10.30574/ijsra.2024.12.2.1251","url":null,"abstract":"The coastal mangroves of Perancak Jembrana Village cover an area of around 177.09 hectares, some of the area (around 10 ha) has been developed into a tourist attraction. The tourism being developed is ecotourism based on ecology, biodiversity, conservation of natural resources, environmental education and economic empowerment of local communities. The aim of the research is to identify and describe the diversity of mangrove flora. Analysis of mangrove vegetation uses the square method, the parameters determined are the number of individuals of each species, the area of canopy cover for each species and the frequency of presence. Diversity was calculated with the Shanon-Wiener index. The research results showed that in the Perancak ecotourism area, 25 mangrove flora were found, consisting of 16 species of true mangrove flora and nine species of associated mangroves. The species that dominate are Rhizophora mucronata (important value 52.63), Rhizophora apiculata (important value 31.93), Avicennia marina (28.70), Rhizophora stylosa (important value 24.81), Avicennia officinalis (important value 17, 73) and Sonneratia alba (important value 16.39). The diversity index (H) is 2.89 and the species evenness index is 0.90. Species diversity in mengrove vegetation with a diversity index >1 and evenness approaching 1 means that the condition of the Perancak mangrove is in the stable/good category. Interpretation of the diversity of mangrove flora, habitus characteristics, fruit morphology, root types, typical substrate types is an interesting attraction for ecotourism activities.","PeriodicalId":14366,"journal":{"name":"International Journal of Science and Research Archive","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141796690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparing ai detectors: evaluating performance and efficiency","authors":"Jeremie Busio Legaspi, Roan Joyce Ohoy Licuben, Emmanuel Alegado Legaspi, Joven Aguinaldo Tolentino","doi":"10.30574/ijsra.2024.12.2.1276","DOIUrl":"https://doi.org/10.30574/ijsra.2024.12.2.1276","url":null,"abstract":"The widespread utilization of AI tools such as ChatGPT has become increasingly prevalent among learners, posing a threat to academic integrity. This study seeks to evaluate capability and efficiency of AI detection tools in distinguishing between human-authored and AI-generated works. Three-paragraph works on “AutoCAD and Architecture” were generated through ChatGPT, and three human-written works were subjected to evaluation. AI detection tools such as GPTZero, Copyleaks and Writer AI were used to evaluate these paragraphs. Parameters such as “Human/Human Text/Human Generated Text” and “AI/AI Content Detected” were used to evaluate the performance of the three AI detection tools in evaluating outputs. Findings indicate that GPT Zero and Copyleaks have higher reliability in determining human-authored work and AI generated work while Writer AI showed a notable content classification of “Human Generated Content” on all tested outputs showing less sensitivity on determining human-authored work and AI generated work. Findings indicate that the use of Artificial Intelligence as an AI detection tool should be accompanied with thorough validation and cross-referencing of results.","PeriodicalId":14366,"journal":{"name":"International Journal of Science and Research Archive","volume":"1 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141795627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Kalaivanan, S. Showbharnikhaa, T. Thenmozhi, S. Preethi, A. Ayisha Siddiqkha, A. Hema Malini, K. Rajaganapathy, R. Srinivasan
{"title":"In-vitro and In-vivo screening methods for targeting HMBG1 in RA: A comprehensive overview","authors":"S. Kalaivanan, S. Showbharnikhaa, T. Thenmozhi, S. Preethi, A. Ayisha Siddiqkha, A. Hema Malini, K. Rajaganapathy, R. Srinivasan","doi":"10.30574/ijsra.2024.12.2.1237","DOIUrl":"https://doi.org/10.30574/ijsra.2024.12.2.1237","url":null,"abstract":"Targeting High Mobility Group Box 1 (HMGB1) in rheumatoid arthritis (RA) holds promise for mitigating inflammation and joint damage. This paper comprehensively overviews In Vitro and In Vivo screening methods for HMGB1 targeting in RA. In Vitro, assays include cell-based assays, ELISA, and Western blotting to assess HMGB1 release, receptor activation, and downstream signalling pathways. In Vivo, models such as collagen-induced arthritis (CIA) in mice and adjuvant-induced arthritis (AIA) in rats mimic RA pathogenesis and enable evaluation of HMGB1 inhibitors' efficacy, safety, and pharmacokinetics. Advanced imaging technologies, including PET and MRI, allow non-invasive visualization of HMGB1 expression In Vivo. Biomarker analyses complement screening methods by correlating HMGB1 levels with disease activity and treatment response. Integration of these screening methods facilitates the development of HMGB1-targeted therapies with the potential to transform RA management. In this review we proposed certain In-vitro and In-vivo screening methods for RA.","PeriodicalId":14366,"journal":{"name":"International Journal of Science and Research Archive","volume":"10 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141795864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A study on the relationship between taekwondo athletes’ psychological capital and athletic achievement","authors":"Wenpeng Zhan","doi":"10.30574/ijsra.2024.12.2.1247","DOIUrl":"https://doi.org/10.30574/ijsra.2024.12.2.1247","url":null,"abstract":"The aim of this study is to investigate how psychological capital can predict athletic achievement among Taekwondo athletes. Data was collected using the psychological capital questionnaire and the athletic achievement scale through a survey of Taekwondo athletes. A total of 421 valid responses were collected with a response rate of 81.7%. The data was analyzed using SEM-PLS. The results show that the psychological capital dimensions of self-efficacy, hope, resilience, and optimism have a significant impact on the athletic achievement of Taekwondo athletes. Among these dimensions, self-efficacy has the greatest impact on athletic achievement, while optimism has the least influence. Overall, psychological capital accounts for 79.6% of the variance in athletic achievement. Based on these results, the study suggests several recommendations for future research.","PeriodicalId":14366,"journal":{"name":"International Journal of Science and Research Archive","volume":"10 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141795866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Tanzanian child with WAGR syndrome: A case report","authors":"Pius David Muzzazzi, Kandi Catherine Muze","doi":"10.30574/ijsra.2024.12.2.1235","DOIUrl":"https://doi.org/10.30574/ijsra.2024.12.2.1235","url":null,"abstract":"WAGR syndrome is a rare genetic disorder characterized by a de novo deletion of 11p 13 (PAX6 and WT1 genes), clinically associated with Wilms’ tumor, aniridia, genitourinary anomalies, and mental retardation. It affects 1 in 500,000 to 1 million people worldwide. Wilms tumor occurs in half of the children with WAGR syndrome. We admitted 3-year-old boy who presented in our institution with the complaints of delay in development milestones and abdomen distension. On thorough examination he was found to have aniridia, Wilms tumor, undescended testis and mental retardation. The observation that aniridia is associated with Wilms tumor led us to believe that the findings were consistent with WAGR syndrome. The diagnosis was confirmed by a genetic testing that revealed loss of 17840kb within the 11p15.1p12 chromosome, confirming the diagnosis of WAGR syndrome.","PeriodicalId":14366,"journal":{"name":"International Journal of Science and Research Archive","volume":"9 49","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141795871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Network protocol-driven real-time tracking radar trajectory simulation using GLG framework for test range applications","authors":"Mitul Goswami, Shashwat Kumar, Sourav Kaity","doi":"10.30574/ijsra.2024.12.2.1245","DOIUrl":"https://doi.org/10.30574/ijsra.2024.12.2.1245","url":null,"abstract":"This research presents an innovative approach to developing a Tracking Radar Trajectory Simulator by integrating advanced network communication protocols and the GLG toolkit framework. The simulator processes raw real-time coordinate system data, specifically in ECEF, ENV, or LLA formats, and converts this to Radar-specific requirements. It serves as a crucial tool for real-time data transmission and visualization of key parameters such as Azimuth Angle, Elevation Angle, and Range, facilitating the study and analysis of Radar trajectory dynamics. The system employs socket programming to enable seamless communication between the simulator and external devices, allowing efficient data exchange in a networked environment. Additionally, it incorporates optimized algorithms to enhance performance and reliability while reducing the time complexity of the simulation. The proposed system surpasses existing state-of-the-art models in terms of agility and performance. Through rigorous experimentation and evaluation, the effectiveness and efficiency of the proposed approach are demonstrated, highlighting its potential applications in Radar technology research and development. This research advances the field of trajectory simulation by providing a robust and scalable solution for real-time data analysis and visualization, contributing significantly to the development of more agile and high-performing tracking systems.","PeriodicalId":14366,"journal":{"name":"International Journal of Science and Research Archive","volume":"5 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141796085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A survey on machine learning system for intraductal papillary mucinous neoplasms detection","authors":"Madhuri Martis, Subramanya Bhat, Sreenivasa B R","doi":"10.30574/ijsra.2024.12.2.1308","DOIUrl":"https://doi.org/10.30574/ijsra.2024.12.2.1308","url":null,"abstract":"IPMN cysts, a pre-malignant risk to the pancreas, have the potential to develop into pancreatic cancer. Accurately identifying and evaluating the risk level is crucial for planning an efficient treatment strategy. However, this task is immensely challenging due to the varied and irregular shapes, textures, and sizes of IPMN cysts, as well as those of the pancreas itself. In this study, we introduce a new computer-aided diagnostic approach for classifying IPMN risk levels based on multi-contrast MRI scans. The proposed analysis framework comprises an efficient volumetric self-adapting segmentation strategy for delineating the pancreas, followed by a newly developed deep learning-based classification scheme incorporating a radiomics-based predictive approach. To evaluate the proposed decision-fusion model, we use multi-centre datasets and multi-contrast MRI scans, aiming to achieve superior performance compared to the current state of the art in this field. The ablation studies illustrate the importance of both radiomics and deep learning modules in achieving a new state-of-the-art (SOTA) performance compared to international guidelines and published studies (81.9% vs 61.3% in accuracy). These key findings carry significant implications for clinical decision-making, potentially revolutionizing the way IPMN risk levels are classified. Through a series of rigorous experiments on multi-centre datasets (involving more MRI scans from five centers), we attained unprecedented performance levels with moderate accuracy. The code will be made available upon publication.","PeriodicalId":14366,"journal":{"name":"International Journal of Science and Research Archive","volume":"4 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141796094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}