International Journal of PIXE最新文献_第3页

Inhibition of metastasis using particles that release chitosan upon radiation: A preliminary study 放射释放壳聚糖颗粒抑制肿瘤转移的初步研究

International Journal of PIXE Pub Date : 2019-01-01 DOI: 10.1142/S0129083519500104

S. Harada, Takahiro Sato

{"title":"Inhibition of metastasis using particles that release chitosan upon radiation: A preliminary study","authors":"S. Harada, Takahiro Sato","doi":"10.1142/S0129083519500104","DOIUrl":"https://doi.org/10.1142/S0129083519500104","url":null,"abstract":"This study aimed to investigate the effect of the particles releasing chitosan upon exposure to radiation on inhibition of metastasis. A 10 mL solution of water containing 0.2% weight/volume alginate, 0.1% hyaluronic acid, and 100-mg chitosan was sprayed into the vibrating solution through a stainless mesh filter (pore size: 0.8 [Formula: see text]m) using an ultrasound disintegrator, thereby generating chitosan particles. Further, [Formula: see text] particles floating in 0.1 mL normal saline were subcutaneously injected around the 4TI cells-derived tumor in the left hind legs of six-week-old male C3He/N mice. Six hours after injection, tumors were exposed to 10 Gy or 20 Gy of 100-keV soft X-ray radiation. The release of chitosan was expressed as the frequency of ruptured chitosan particles 12 h after radiation. The antimetastatic effect was confirmed by a reduction in the number of metastatic pulmonary nodules 21 days after completion of treatment. More than [Formula: see text]% of the chitosan particles released chitosan in response to radiation. The particles releasing chitosan had a prolonged antimetastatic effect when compared with the particles not releasing chitosan, thereby resulting in a significantly greater antimetastatic effect lasting for four weeks since the completion of treatment, in tumors treated with both 10 Gy and 20 Gy of radiation. Hence, particlizing chitosan could be useful in reducing metastasis in irradiated tumors.","PeriodicalId":14345,"journal":{"name":"International Journal of PIXE","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83472112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantification of major and trace elements contained in aircraft JET A-1 fuel by in-vacuum PIXE analysis JET A-1飞机燃料中主要和微量元素的定量分析

International Journal of PIXE Pub Date : 2019-01-01 DOI: 10.1142/S0129083519500165

K. Saitoh, A. Fushimi, N. Takegawa, K. Sera

{"title":"Quantification of major and trace elements contained in aircraft JET A-1 fuel by in-vacuum PIXE analysis","authors":"K. Saitoh, A. Fushimi, N. Takegawa, K. Sera","doi":"10.1142/S0129083519500165","DOIUrl":"https://doi.org/10.1142/S0129083519500165","url":null,"abstract":"To characterize the chemical composition of aircraft exhaust particles, we developed a treatment method of jet fuel for an elemental analysis by an in-vacuum PIXE system. Eleven elements (Si, S, Cl, K, Ca, Cr, Fe, Ni, Cu, Zn, and Pb) were identified from each sample. The concentrations of S from five JET A-1 fuel samples collected on different days ranged from 30.4 to 440 wt.-ppm. The concentration level of S agreed well with the measurement results obtained by an in-air PIXE analysis, which we have previously performed to determine the major content elements and their concentration levels. Nine elements out of the identified 11 elements (Si, Cl, K, Ca, Cr, Ni, Cu, Zn, and Pb), which were not detected by the in-air PIXE analysis, were detected in all the JET A-1 fuel samples measured. Among these elements, Si, Ni, Cu, Zn, and Pb were found to be the major components. It is suggested that particles emitted from aircraft jet engines, which are generally in the size range smaller than 100 nm (ultrafine particles: UFPs), may contain Si, Ni, Cu, Zn, and Pb. These findings provide useful insights into the source apportionment of UFPs in and around airports.","PeriodicalId":14345,"journal":{"name":"International Journal of PIXE","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77266455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Long-term and season-specific changes in the body concentrations of iron, copper, zinc, and selenium by means of quantitative analyses of beard samples collected every day — A case study 通过对每天收集的胡须样本进行定量分析，研究人体铁、铜、锌和硒浓度的长期和季节变化-一个案例研究

International Journal of PIXE Pub Date : 2019-01-01 DOI: 10.1142/s0129083519500207

K. Sera, S. Goto, T. Hosokawa, Y. Saitoh

{"title":"Long-term and season-specific changes in the body concentrations of iron, copper, zinc, and selenium by means of quantitative analyses of beard samples collected every day — A case study","authors":"K. Sera, S. Goto, T. Hosokawa, Y. Saitoh","doi":"10.1142/s0129083519500207","DOIUrl":"https://doi.org/10.1142/s0129083519500207","url":null,"abstract":"A total of 4269 beard samples were collected from the same person every day over a 12-year period and analyzed by PIXE using a standard-free method. It was found that the concentrations of copper and zinc showed certain short-term changes but did not show a noticeable long-term trend over the study period, with only iron showing a slightly decreasing tendency with age. All of these elements showed clear yearly variations with a cycle of a few years possibly due to periodic metabolic changes in the subject’s body or long-term changes in eating habits. In contrast, however, selenium showed clear seasonal variations. Its concentration significantly increased in the summer and decreased in the winter, just as was observed with arsenic and mercury. This suggests that most of the subject’s selenium intake was from marine products, whose supply and consumption were increased in the summer. These findings confirmed that beard analyses are useful not only for evaluating essential-element intake but also for estimating the relationship between the body-element concentrations and ingestion of certain foods.","PeriodicalId":14345,"journal":{"name":"International Journal of PIXE","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78412446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of tooth-bound fluoride after the application of coating materials on the enamel surface with an in-air micro PIXE/PIGE 在牙釉质表面应用涂层材料后，用空气微型PIXE/PIGE分析牙结合氟化物

International Journal of PIXE Pub Date : 2019-01-01 DOI: 10.1142/s0129083519500116

K. Okuyama, Y. Tamaki, Y. Matsuda, T. Saito, H. Yamamoto, K. Naito, M. Hayashi, K. Suzuki

{"title":"Analysis of tooth-bound fluoride after the application of coating materials on the enamel surface with an in-air micro PIXE/PIGE","authors":"K. Okuyama, Y. Tamaki, Y. Matsuda, T. Saito, H. Yamamoto, K. Naito, M. Hayashi, K. Suzuki","doi":"10.1142/s0129083519500116","DOIUrl":"https://doi.org/10.1142/s0129083519500116","url":null,"abstract":"Tooth-bound (KOH-insoluble) fluoride prevents caries via long retention within the tooth structure. Tooth-bound fluoride in the enamel was investigated after applying various fluoride-containing tooth-coating materials using an in-air micro [Formula: see text] PIXE/PIGE system. Three different fluoride-containing or a non-fluoride containing coating materials were applied to the coronal enamel surface of 24 extracted human molars. The samples were stored in water for 1 or 7 days and then sectioned into two slices. One slice was immersed in 1M KOH solution for 24 h for KOH-insoluble fluoride (KOH(T)) analysis. The second slice was not subjected to KOH treatment and was used to analyze the whole fluoride (KOH-soluble plus insoluble fluoride: KOH(U)). Fluorine and calcium distribution were measured in all the slices with [Formula: see text]PIXE/PIGE. KOH(U) was higher than KOH(T) on some materials, especially those that released more fluoride. For KOH(T), there was no significant difference among all fluoride-containing materials in the 7-day group. However, there were significant differences in the KOH(U) samples during the same period. PIXE/PIGE analysis confirmed the presence of tooth-bound fluoride in the enamel adjacent to the fluoride-containing coating materials. The amount of tooth-bound fluoride depended on the type of material.","PeriodicalId":14345,"journal":{"name":"International Journal of PIXE","volume":"280 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86270081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Development of a 20MeV proton particle-induced X-ray emission analysis method in a helium atmosphere 氦大气中20MeV质子粒子诱导x射线发射分析方法的建立

International Journal of PIXE Pub Date : 2019-01-01 DOI: 10.1142/s0129083519500219

K. Ishii, A. Terakawa, K. Hitomi, M. Nogami

引用次数: 0

FT-IR measurement on the damage of Japanese paper induced by PIXE analysis FT-IR对日本纸pixie损伤的测量

International Journal of PIXE Pub Date : 2019-01-01 DOI: 10.1142/S012908351950013X

Y. Oguri, J. Hasegawa, H. Fukuda, N. Hagura

引用次数: 0

Adsorption behavior of Cs+ ions to vermiculite demonstrated by molecular dynamics simulations 分子动力学模拟研究了Cs+离子在蛭石上的吸附行为

International Journal of PIXE Pub Date : 2018-01-01 DOI: 10.1142/s0129083519500013

A. Takeuchi

引用次数: 1

Mineral pigment studies on ancient ceramics and glass artifacts from commercial settlements on Danube border between Muntenia and Dobruja 蒙泰尼亚和多布鲁加之间多瑙河边界商业定居点古代陶瓷和玻璃文物的矿物颜料研究

International Journal of PIXE Pub Date : 2018-01-01 DOI: 10.1142/s0129083519500025

B. Constantinescu, D. Cristea-Stan, I. Kovács, Z. Szökefalvi-nagy, I. Poll

引用次数: 0

Analysis of strontium in soil and plant samples contaminated during the 2011 Fukushima Daiichi Nuclear Power Plant accident 2011年福岛第一核电站事故污染土壤和植物样品中的锶分析

International Journal of PIXE Pub Date : 2018-01-01 DOI: 10.1142/s0129083519500049

K. Ishii, H. Arai, Tohru Ohnuma, A. Takeuchi

引用次数: 1

Elemental characterization of gold-plated costume jewelry using particle-induced X-ray emission 使用粒子诱导x射线发射的镀金人造珠宝的元素表征

International Journal of PIXE Pub Date : 2018-01-01 DOI: 10.1142/s0129083519500074

R. Debastiani, I. Almansa, L. A. Boufleur, T. M. Ferrari, C. T. Souza, D. Bauer, L. Amaral, J. Dias

引用次数: 1