Charles S Urwin, Rodney J Snow, Dominique Condo, Rhiannon M J Snipe, Glenn D Wadley, Lilia Convit, Amelia J Carr
{"title":"A Comparison of Sodium Citrate and Sodium Bicarbonate Ingestion: Blood Alkalosis and Gastrointestinal Symptoms.","authors":"Charles S Urwin, Rodney J Snow, Dominique Condo, Rhiannon M J Snipe, Glenn D Wadley, Lilia Convit, Amelia J Carr","doi":"10.1123/ijsnem.2022-0083","DOIUrl":"https://doi.org/10.1123/ijsnem.2022-0083","url":null,"abstract":"<p><p>This study compared the recommended dose of sodium citrate (SC, 500 mg/kg body mass) and sodium bicarbonate (SB, 300 mg/kg body mass) for blood alkalosis (blood [HCO3-]) and gastrointestinal symptoms (GIS; number and severity). Sixteen healthy individuals ingested the supplements in a randomized, crossover design. Gelatin capsules were ingested over 15 min alongside a carbohydrate-rich meal, after which participants remained seated for forearm venous blood sample collection and completion of GIS questionnaires every 30 min for 300 min. Time-course and session value (i.e., peak and time to peak) comparisons of SC and SB supplementation were performed using linear mixed models. Peak blood [HCO3-] was similar for SC (mean 34.2, 95% confidence intervals [33.4, 35.0] mmol/L) and SB (mean 33.6, 95% confidence intervals [32.8, 34.5] mmol/L, p = .308), as was delta blood [HCO3-] (SC = 7.9 mmol/L; SB = 7.3 mmol/L, p = .478). Blood [HCO3-] was ≥6 mmol/L above baseline from 180 to 240 min postingestion for SC, significantly later than for SB (120-180 min; p < .001). GIS were mostly minor, and peaked 80-90 min postingestion for SC, and 35-50 min postingestion for SB. There were no significant differences for the number or severity of GIS reported (p > .05 for all parameters). In summary, the recommended doses of SC and SB induce similar blood alkalosis and GIS, but with a different time course.</p>","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":"33 1","pages":"1-10"},"PeriodicalIF":2.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10451731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"For Flux Sake: Isotopic Tracer Methods of Monitoring Human Carbohydrate Metabolism During Exercise.","authors":"Javier T Gonzalez, Andy J King","doi":"10.1123/ijsnem.2022-0170","DOIUrl":"https://doi.org/10.1123/ijsnem.2022-0170","url":null,"abstract":"<p><p>Isotopic tracers can reveal insights into the temporal nature of metabolism and track the fate of ingested substrates. A common use of tracers is to assess aspects of human carbohydrate metabolism during exercise under various established models. The dilution model is used alongside intravenous infusion of tracers to assess carbohydrate appearance and disappearance rates in the circulation, which can be further delineated into exogenous and endogenous sources. The incorporation model can be used to estimate exogenous carbohydrate oxidation rates. Combining methods can provide insight into key factors regulating health and performance, such as muscle and liver glycogen utilization, and the underlying regulation of blood glucose homeostasis before, during, and after exercise. Obtaining accurate, quantifiable data from tracers, however, requires careful consideration of key methodological principles. These include appropriate standardization of pretrial diet, specific tracer choice, whether a background trial is necessary to correct expired breath CO2 enrichments, and if so, what the appropriate background trial should consist of. Researchers must also consider the intensity and pattern of exercise, and the type, amount, and frequency of feeding (if any). The rationale for these considerations is discussed, along with an experimental design checklist and equation list which aims to assist researchers in performing high-quality research on carbohydrate metabolism during exercise using isotopic tracer methods.</p>","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":"33 1","pages":"60-70"},"PeriodicalIF":2.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10428659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acknowledgments","authors":"","doi":"10.1123/ijsnem.2022-0234","DOIUrl":"https://doi.org/10.1123/ijsnem.2022-0234","url":null,"abstract":"Journal Name: International Journal of Sport Nutrition and Exercise Metabolism<br/>Volume: 33<br/>Issue: 1<br/>Pages: 71-71","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":"278 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2022-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138505605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrew T Askow, Kevin J M Paulussen, Colleen F McKenna, Amadeo F Salvador, Susannah E Scaroni, Jade S Hamann, Alexander V Ulanov, Zhong Li, Scott A Paluska, Kayleigh M Beaudry, Michael De Lisio, Nicholas A Burd
{"title":"Creatine Monohydrate Supplementation, but not Creatyl-L-Leucine, Increased Muscle Creatine Content in Healthy Young Adults: A Double-Blind Randomized Controlled Trial.","authors":"Andrew T Askow, Kevin J M Paulussen, Colleen F McKenna, Amadeo F Salvador, Susannah E Scaroni, Jade S Hamann, Alexander V Ulanov, Zhong Li, Scott A Paluska, Kayleigh M Beaudry, Michael De Lisio, Nicholas A Burd","doi":"10.1123/ijsnem.2022-0074","DOIUrl":"https://doi.org/10.1123/ijsnem.2022-0074","url":null,"abstract":"<p><p>Creatine (Cr) supplementation is a well-established strategy to enhance gains in strength, lean body mass, and power from a period of resistance training. However, the effectiveness of creatyl-L-leucine (CLL), a purported Cr amide, is unknown. Therefore, the purpose of this study was to assess the effects of CLL on muscle Cr content. Twenty-nine healthy men (n = 17) and women (n = 12) consumed 5 g/day of either Cr monohydrate (n = 8; 28.5 ± 7.3 years, 172.1 ± 11.0 cm, 76.6 ± 10.7 kg), CLL (n = 11; 29.2 ± 9.3 years, 170.3 ± 10.5 cm, 71.9 ± 14.5 kg), or placebo (n = 10; 30.3 ± 6.9 years, 167.8 ± 9.9 cm, 69.9 ± 11.1 kg) for 14 days in a randomized, double-blind design. Participants completed three bouts of supervised resistance exercise per week. Muscle biopsies were collected before and after the intervention for quantification of muscle Cr. Cr monohydrate supplementation which significantly increased muscle Cr content with 14 days of supplementation. No changes in muscle Cr were observed for the placebo or CLL groups. Cr monohydrate supplementation is an effective strategy to augment muscle Cr content while CLL is not.</p>","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":"32 6","pages":"446-452"},"PeriodicalIF":2.5,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9755768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on: \"Association of Vitamin D Supplementation in Cardiorespiratory Fitness and Muscle Strength in Adult Twins: A Randomized Controlled Trial\".","authors":"Nicholas B Tiller","doi":"10.1123/ijsnem.2022-0101","DOIUrl":"10.1123/ijsnem.2022-0101","url":null,"abstract":"","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":"61 1","pages":"419-420"},"PeriodicalIF":3.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84027648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erratum. Heat Adaptation and Nutrition Practices: Athlete and Practitioner Knowledge and Use.","authors":"","doi":"10.1123/ijspp.2022-0128","DOIUrl":"https://doi.org/10.1123/ijspp.2022-0128","url":null,"abstract":"<p><p>TO OUR READERS: An error appeared in the ahead-of-print version of the following article: Alabdulwahed S, Galán-López N, Hill T, et al. Heat adaptation and nutrition practices: athlete and practitioner knowledge and use [published online March 24, 2022]. Int J Sports Physiol Perform. https://doi.org/10.1123/ijspp.2021-0462. The wrong versions of Figures 1–4 were placed in the article, and in Supplementary Material S3 posted online with the article, the figure captions did not match up correctly with the figures. The article was corrected April 20, 2022. We apologize for this error.</p>","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":"17 6","pages":"991"},"PeriodicalIF":2.5,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10524850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retraction: Medeiros et al. (2022).","authors":"J. Betts","doi":"10.1123/ijsnem.2022-0104","DOIUrl":"https://doi.org/10.1123/ijsnem.2022-0104","url":null,"abstract":"This issue of the International Journal of Sport Nutrition and Metabolism (IJSNEM) includes a letter to the editor (Tiller, 2022) that expresses concern regarding a recently published paper by Medeiros et al. (2022). The expression of concern primarily relates to the maximal oxygen uptake (V̇O2max) data in the study. Specifically, our reader noticed that the magnitude of change in absolute V̇O2max (L·min ) after 60 days of vitamin D supplementation (i.e. 28% increase) is both physiologically implausible when considering the known responsivity of that parameter to various interventions and, moreover, is mathematically incompatible with the completely stable relative V̇O2max (mL·kg ·min) values reported in the same paper (unless body mass changed by circa 18 kg). The authors of the original article were asked to provide an explanation for the apparent inconsistencies, along with their source data, in the hope that an erratum might clarify and/or correct any issues. No coherent explanation or adequate response to the expression of concern could be obtained from the authors, although various revised data files were made available. In summary, those revised data still included unprecedented changes in absolute V̇O2max (L·min ) at both a group and especially an individual level, with no logical reason to account for that variance; whereas the authors now acknowledge that some of the relative V̇O2max (mL·kg ·min) data in their original manuscript were incorrect (it is uncertain how these errors occurred). Unfortunately, it appears that almost one-third of the original measurements have been lost and so it is now impossible to recover relative V̇O2max data for the complete study population (n.b. relative data cannot be retrospectively derived from absolute values since the authors claim not to have recorded body mass). It is therefore necessary to retract the original article on the basis that the originally published data are now known to be inaccurate and a complete set of corrected data are not available. Interested readers can consider for themselves the various other issues identified in the associated expression of concern (Tiller, 2022), including the puzzling effect of vitamin D on strength in only one arm (but not the other) and the mis-citation of key references. In terms of lessons to be learnt from this instance, it is firstly regrettable that these particular issues with the data were not identified during the peer-review process, for which I take primary responsibility as Editor-in-Chief. We are therefore refining our processes at IJSNEMwith immediate effect, such that authors will increasingly be asked to provide source data files where relevant when responding to reviewer/editorial comments. Furthermore, authors are encouraged to adhere to best practice for data management (Nightingale, 2020) and certainly to retain source data (ideally in a public repository). One practical suggestion would be for some/all co-authors to be provided with ","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":"14 1","pages":"1"},"PeriodicalIF":2.5,"publicationDate":"2022-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72950626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ivy Evangelista Ramos, Gabriela Morgado de Oliveira Coelho, H. S. Lanzillotti, E. Marini, J. Koury
{"title":"Fat-Free Mass Using Bioelectrical Impedance Analysis as an Alternative to Dual-Energy X-Ray Absorptiometry in Calculating Energy Availability in Female Adolescent Athletes.","authors":"Ivy Evangelista Ramos, Gabriela Morgado de Oliveira Coelho, H. S. Lanzillotti, E. Marini, J. Koury","doi":"10.1123/ijsnem.2021-0301","DOIUrl":"https://doi.org/10.1123/ijsnem.2021-0301","url":null,"abstract":"Energy availability (EA) is calculated by subtracting exercise energy expenditure from energy intake, adjusted for fat-free mass (FFM) obtained using accurate methods, such as dual-energy X-ray absorptiometry (DXA). Unlike DXA, the bioelectrical impedance analysis (BIA) is low in cost, simple and easy to carry out. This study aimed to test the concordance between the calculation of EA using FFM values from four BIA predictive equations and FFM obtained using DXA in female adolescent athletes (n = 94), recruited via social media. Paired Student's t test, Wilcoxon test, Lin's concordance correlation coefficient, root mean square error, limits of agreement, and mean absolute percentage error were used to evaluate agreement between the FFM values obtained by the four SF-BIA predictive equations and DXA. Regression linear analysis was used to determine the relation between FFM values obtained using DXA and the BIA predictive equations. Standardized residuals of the FFM and EA were calculated considering DXA values as reference. The most appropriate model for the FFM (limits of agreement = 4.0/-2.6 kg, root mean square error = 1.9 kg, mean absolute percentage error = 4.34%, Lin's concordance correlation coefficient = .926) and EA (limits of agreement = 2.51/4.4 kcal·kg FFM-1·day-1, root mean square error = 1.8 kcal·kg FFM-1·day-1, mean absolute percentage error 4.24%, Lin's concordance correlation coefficient = .992) was the equation with sexual maturity as a variable, while the equation with the greatest age variability was the one with the lowest agreement. FFM-BIA predictive equations can be used to calculate EA of female adolescent athletes. However, the equation should be chosen considering sex, age, and maturation status. In the case of athletes, researchers should use equations developed for this group.","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":"15 1","pages":"1-9"},"PeriodicalIF":2.5,"publicationDate":"2022-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79889007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah Gehman, Kathryn E. Ackerman, Signe Caksa, S. Rudolph, J. Hughes, Margaret Garrahan, A. Tenforde, M. Bouxsein, Kristin L. Popp
{"title":"Restrictive Eating and Prior Low-Energy Fractures Are Associated With History of Multiple Bone Stress Injuries.","authors":"Sarah Gehman, Kathryn E. Ackerman, Signe Caksa, S. Rudolph, J. Hughes, Margaret Garrahan, A. Tenforde, M. Bouxsein, Kristin L. Popp","doi":"10.1123/ijsnem.2021-0323","DOIUrl":"https://doi.org/10.1123/ijsnem.2021-0323","url":null,"abstract":"Bone stress injuries (BSIs) are common among athletes and have high rates of recurrence. However, risk factors for multiple or recurrent BSIs remain understudied. Thus, we aimed to explore whether energy availability, menstrual function, measures of bone health, and a modified Female Athlete Triad Cumulative Risk Assessment (CRA) tool are associated with a history of multiple BSIs. We enrolled 51 female runners (ages 18-36 years) with history of ≤1 BSI (controls; n = 31) or ≥3 BSIs (multiBSI; n = 20) in this cross-sectional study. We measured lumbar spine, total hip, and femoral neck areal bone mineral density by dual-energy X-ray absorptiometry, bone material strength index using impact microindentation, and volumetric bone mineral density, microarchitecture, and estimated strength by high-resolution peripheral quantitative computed tomography. Participants completed questionnaires regarding medical history, low-energy fracture history, and disordered eating attitudes. Compared with controls, multiBSI had greater incidence of prior low-energy fractures (55% vs. 16%, p = .005) and higher modified Triad CRA scores (2.90 ± 2.05 vs. 1.84 ± 1.59, p = .04). Those with multiBSI had higher Eating Disorder Examination Questionnaire (0.92 ± 1.03 vs. 0.46 ± 0.49, p = .04) scores and a greater percentage difference between lowest and highest body mass at their current height (15.5% ± 6.5% vs. 11.5% ± 4.9% p = .02). These preliminary findings indicate that women with a history of multiple BSIs suffered more prior low-energy fractures and have greater historical and current estimates of energy deficit compared with controls. Our results provide strong rationale for future studies to examine whether subclinical indicators of energy deficit contribute to risk for multiple BSIs in female runners.","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":"6 1","pages":"1-9"},"PeriodicalIF":2.5,"publicationDate":"2022-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86315104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erratum: Fensham et al. (2021).","authors":"","doi":"10.1123/ijsnem.2022-0002","DOIUrl":"https://doi.org/10.1123/ijsnem.2022-0002","url":null,"abstract":"<p><p>In the article Fensham, N.C., McKay, A.K.A., Tee, N., Lundy, B., Anderson, B., Morabito, A., Ross, M.L.R., & Burke, L.M. (2021). Sequential submaximal training in elite male rowers does not result in amplified increases in interleukin-6 or hepcidin. International Journal of Sport Nutrition and Exercise Metabolism, Advanced online publication, https://doi.org/10.1123/ijsnem.2021-0263, an error was introduced in the fourth sentence of the abstract. The sentence should read “Each trial involved two, submaximal 90-min rowing ergometer sessions, 2.5 hr apart, with venous blood sampled at baseline; pre-exercise; and 0, 1, 2, and 3 hr after each session.” The online version of this article has been corrected. We apologize for the error.</p>","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":"32 3","pages":"226"},"PeriodicalIF":2.5,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10524848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}