International journal of sport nutrition and exercise metabolism最新文献

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Impact of 24-Hr Diet and Physical Activity Control on Short-Term Precision Error of Dual-Energy X-Ray Absorptiometry Physique Assessment. 24小时饮食和运动控制对双能x线吸收体质评估短期精度误差的影响
IF 2.5 3区 医学
International journal of sport nutrition and exercise metabolism Pub Date : 2023-01-01 DOI: 10.1123/ijsnem.2022-0125
Gary J Slater, Ava Farley, Luke Hogarth, Jose L Areta, Gøran Paulsen, Ina Garthe
{"title":"Impact of 24-Hr Diet and Physical Activity Control on Short-Term Precision Error of Dual-Energy X-Ray Absorptiometry Physique Assessment.","authors":"Gary J Slater,&nbsp;Ava Farley,&nbsp;Luke Hogarth,&nbsp;Jose L Areta,&nbsp;Gøran Paulsen,&nbsp;Ina Garthe","doi":"10.1123/ijsnem.2022-0125","DOIUrl":"https://doi.org/10.1123/ijsnem.2022-0125","url":null,"abstract":"<p><p>Dual-energy X-ray absorptiometry (DXA) is a popular technique used to quantify physique in athletic populations. Due to biological variation, DXA precision error (PE) may be higher than desired. Adherence to standardized presentation for testing has shown improvement in consecutive-day PE. However, the impact of short-term diet and physical activity standardization prior to testing has not been explored. This warrants investigation, given the process may reduce variance in total body water and muscle solute, both of which can have high daily flux amongst athletes. Twenty (n = 10 males, n = 10 females) recreationally active individuals (age: 30.7 ± 7.5 years; stature: 176.4 ± 9.1 cm; mass: 74.6 ± 14.3 kg) underwent three DXA scans; two consecutive scans on 1 day, and a third either the day before or after. In addition to adhering to standardized presentation for testing, subjects recorded all food/fluid intake plus activity undertaken in the 24 hr prior to the first DXA scan and replicated this the following 24 hr. International Society of Clinical Densitometry recommended techniques were used to calculate same- and consecutive-day PE. There was no significant difference in PE of whole-body fat mass (479 g vs. 626 g) and lean mass (634 g vs. 734 g) between same- and consecutive-day assessments. Same- and consecutive-day PE of whole-body fat mass and lean mass were less than the smallest effect size of interest. Inclusion of 24-hr standardization of diet and physical activity has the potential to reduce biological error further, but this needs to be verified with follow-up investigation.</p>","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":"33 1","pages":"30-38"},"PeriodicalIF":2.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10428128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Cardiorespiratory Fitness and Bone Turnover Markers in Adults With Metabolic Syndrome: The Mediator Role of Inflammation. 成人代谢综合征的心肺健康和骨转换标志物:炎症的中介作用。
IF 2.5 3区 医学
International journal of sport nutrition and exercise metabolism Pub Date : 2023-01-01 DOI: 10.1123/ijsnem.2022-0109
José J Gil-Cosano, Luis Gracia-Marco, Daniel Courteix, Bruno Lesourd, Robert Chapier, Philippe Obert, Guillaume Walther, Agnes Vinet, David Thivel, Manuel Muñoz-Torres, Ukadike C Ugbolue, Reza Bagheri, Marek Zak, Frédéric Dutheil, Esther Ubago-Guisado
{"title":"Cardiorespiratory Fitness and Bone Turnover Markers in Adults With Metabolic Syndrome: The Mediator Role of Inflammation.","authors":"José J Gil-Cosano,&nbsp;Luis Gracia-Marco,&nbsp;Daniel Courteix,&nbsp;Bruno Lesourd,&nbsp;Robert Chapier,&nbsp;Philippe Obert,&nbsp;Guillaume Walther,&nbsp;Agnes Vinet,&nbsp;David Thivel,&nbsp;Manuel Muñoz-Torres,&nbsp;Ukadike C Ugbolue,&nbsp;Reza Bagheri,&nbsp;Marek Zak,&nbsp;Frédéric Dutheil,&nbsp;Esther Ubago-Guisado","doi":"10.1123/ijsnem.2022-0109","DOIUrl":"https://doi.org/10.1123/ijsnem.2022-0109","url":null,"abstract":"<p><p>The relationship between inflammatory markers and bone turnover in adults is well known, and a negative association between cardiorespiratory fitness (CRF) and inflammatory markers has also been described. Hence, we tested whether the association between CRF and bone turnover markers is mediated by inflammatory markers in adults with metabolic syndrome. A total of 81 adults (58.5 ± 5.0 years, 62.7% women) were included in the analysis. CRF was measured by the 6-min walking test. Serum interleukin (IL)-1β, IL-6, IL-10, tumor necrosis factor alpha, high-sensitivity c-reactive protein (hsCRP) and vascular endothelial growth factor, collagen type I cross-linked C-telopeptide, procollagen type I N-terminal propeptide (P1NP), and total osteocalcin were assessed using a sensitive ELISA kit. Body composition was assessed by dual-energy X-ray absorptiometry. Partial correlation was used to test the relationship between CRF, inflammatory markers, and bone turnover markers, controlling for sex, lean mass, and fat mass. Boot-strapped mediation procedures were performed, and indirect effects with confidence intervals not including zero were interpreted as statistically significant. CRF was positively correlated with P1NP levels (r = .228, p = .044) and osteocalcin levels (r = .296, p = .009). Furthermore, CRF was positively correlated with IL-1β levels (r = .340, p = .002) and negatively correlated with hsCRP levels (r = -.335, p = .003), whereas IL-1β levels were positively correlated with P1NP levels (r = .245, p = .030), and hsCRP levels were negatively correlated with P1NP levels (r = -.319, p = .004). Finally, the association between CRF and P1NP levels was totally mediated by hsCRP (percentage of mediation = 39.9). Therefore, CRF benefits on bone formation could be dependent on hsCRP concentrations in this population.</p>","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":"33 1","pages":"23-29"},"PeriodicalIF":2.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10428129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A Delayed Evening Meal Enhances Sleep Quality in Young Rugby Players. 晚餐会提高年轻橄榄球运动员的睡眠质量。
IF 2.5 3区 医学
International journal of sport nutrition and exercise metabolism Pub Date : 2023-01-01 DOI: 10.1123/ijsnem.2022-0014
Lisa Lehmann, Oussama Saidi, Magali Giacomoni, Giovanna Del Sordo, Freddy Maso, Irène Margaritis, Pascale Duché
{"title":"A Delayed Evening Meal Enhances Sleep Quality in Young Rugby Players.","authors":"Lisa Lehmann,&nbsp;Oussama Saidi,&nbsp;Magali Giacomoni,&nbsp;Giovanna Del Sordo,&nbsp;Freddy Maso,&nbsp;Irène Margaritis,&nbsp;Pascale Duché","doi":"10.1123/ijsnem.2022-0014","DOIUrl":"https://doi.org/10.1123/ijsnem.2022-0014","url":null,"abstract":"<p><p>The aim of this study was to examine the effect of delayed evening mealtime on sleep quality in young athletes. Twelve rugby players (age 15.8 ± 0.7 years) participated in a crossover within-participant design. Adolescents spent five consecutive days in each of two conditions, separated by a 2-week washout period: routine dinner (3.5 hr before bedtime) and late dinner (LD, 1.5 hr before bedtime). Other mealtimes as well as bedtime and wake-up time were usual and remained the same in both conditions. Their schedules, dietary intakes, and physical activity were controlled and kept constant throughout the study. Sleep was assessed using polysomnography on the first and the last nights in the individual rooms of the boarding school. An increase in total sleep time by 24 min (p = .001, d = 1.24) and sleep efficiency by 4.8% was obtained during LD (p = .001, d = 1.24). Improvement in sleep efficiency was mainly due to a lower wake after sleep onset (-25 min, p = .014, d = -3.20), a decrease of microarousals (-25%, p = .049, d = -0.64), and awakenings ≥90 s (-30%, p < .01, d = -0.97) in LD compared to routine dinner. There were no significant differences in sleep architecture except for a shorter slow-wave sleep (N3) latency (-6.9 min, p = .03, d = -0.778) obtained during LD. In this study, evening dinner 1.5 hr before bedtime leads to better quality and less fragmented sleep compared to evening dinner 3.5 hr before bedtime in young athletes.</p>","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":"33 1","pages":"39-46"},"PeriodicalIF":2.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10419384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Effects of Physical Exercise Training on Cerebral Blood Flow Measurements: A Systematic Review of Human Intervention Studies. 体育锻炼对脑血流测量的影响:人为干预研究的系统回顾。
IF 2.5 3区 医学
International journal of sport nutrition and exercise metabolism Pub Date : 2023-01-01 DOI: 10.1123/ijsnem.2022-0085
Jordi P D Kleinloog, Kevin M R Nijssen, Ronald P Mensink, Peter J Joris
{"title":"Effects of Physical Exercise Training on Cerebral Blood Flow Measurements: A Systematic Review of Human Intervention Studies.","authors":"Jordi P D Kleinloog,&nbsp;Kevin M R Nijssen,&nbsp;Ronald P Mensink,&nbsp;Peter J Joris","doi":"10.1123/ijsnem.2022-0085","DOIUrl":"https://doi.org/10.1123/ijsnem.2022-0085","url":null,"abstract":"<p><p>The aim of this systematic review was to examine the effects of physical exercise training on cerebral blood flow (CBF), which is a physiological marker of cerebrovascular function. Relationships between training-induced effects on CBF with changes in cognitive performance were also discussed. A systematic search was performed up to July 2022. Forty-five intervention studies with experimental, quasi-experimental, or pre-post designs were included. Sixteen studies (median duration: 14 weeks) investigated effects of physical exercise training on CBF markers using magnetic resonance imaging, 20 studies (median duration: 14 weeks) used transcranial Doppler ultrasound, and eight studies (median duration: 8 weeks) used near-infrared spectroscopy. Studies using magnetic resonance imaging observed consistent increases in CBF in the anterior cingulate cortex and hippocampus, but not in whole-brain CBF. Effects on resting CBF-measured with transcranial Doppler ultrasound and near-infrared spectroscopy-were variable, while middle cerebral artery blood flow velocity increased in some studies following exercise or hypercapnic stimuli. Interestingly, concomitant changes in physical fitness and regional CBF were observed, while a relation between training-induced effects on CBF and cognitive performance was evident. In conclusion, exercise training improved cerebrovascular function because regional CBF was changed. Studies are however still needed to establish whether exercise-induced improvements in CBF are sustained over longer periods of time and underlie the observed beneficial effects on cognitive performance.</p>","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":"33 1","pages":"47-59"},"PeriodicalIF":2.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10432543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Fasting Before Evening Exercise Reduces Net Energy Intake and Increases Fat Oxidation, but Impairs Performance in Healthy Males and Females. 晚上运动前禁食会减少净能量摄入,增加脂肪氧化,但会损害健康男性和女性的表现。
IF 2.5 3区 医学
International journal of sport nutrition and exercise metabolism Pub Date : 2023-01-01 DOI: 10.1123/ijsnem.2022-0132
Tommy Slater, William J A Mode, Mollie G Pinkney, John Hough, Ruth M James, Craig Sale, Lewis J James, David J Clayton
{"title":"Fasting Before Evening Exercise Reduces Net Energy Intake and Increases Fat Oxidation, but Impairs Performance in Healthy Males and Females.","authors":"Tommy Slater,&nbsp;William J A Mode,&nbsp;Mollie G Pinkney,&nbsp;John Hough,&nbsp;Ruth M James,&nbsp;Craig Sale,&nbsp;Lewis J James,&nbsp;David J Clayton","doi":"10.1123/ijsnem.2022-0132","DOIUrl":"https://doi.org/10.1123/ijsnem.2022-0132","url":null,"abstract":"<p><p>Acute morning fasted exercise may create a greater negative 24-hr energy balance than the same exercise performed after a meal, but research exploring fasted evening exercise is limited. This study assessed the effects of 7-hr fasting before evening exercise on energy intake, metabolism, and performance. Sixteen healthy males and females (n = 8 each) completed two randomized, counterbalanced trials. Participants consumed a standardized breakfast (08:30) and lunch (11:30). Two hours before exercise (16:30), participants consumed a meal (543 ± 86 kcal; FED) or remained fasted (FAST). Exercise involved 30-min cycling (∼60% VO2peak) and a 15-min performance test (∼85% VO2peak; 18:30). Ad libitum energy intake was assessed 15 min postexercise. Subjective appetite was measured throughout. Energy intake was 99 ± 162 kcal greater postexercise (p < .05), but 443 ± 128 kcal lower over the day (p < .001) in FAST. Appetite was elevated between the preexercise meal and ad libitum meal in FAST (p < .001), with no further differences (p ≥ .458). Fat oxidation was greater (+3.25 ± 1.99 g), and carbohydrate oxidation was lower (-9.16 ± 5.80 g) during exercise in FAST (p < .001). Exercise performance was 3.8% lower in FAST (153 ± 57 kJ vs. 159 ± 58 kJ, p < .05), with preexercise motivation, energy, readiness, and postexercise enjoyment also lower in FAST (p < .01). Fasted evening exercise reduced net energy intake and increased fat oxidation compared to exercise performed 2 hr after a meal. However, fasting also reduced voluntary performance, motivation, and exercise enjoyment. Future studies are needed to examine the long-term effects of this intervention as a weight management strategy.</p>","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":"33 1","pages":"11-22"},"PeriodicalIF":2.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10813218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A Comparison of Sodium Citrate and Sodium Bicarbonate Ingestion: Blood Alkalosis and Gastrointestinal Symptoms. 柠檬酸钠和碳酸氢钠摄入的比较:血碱中毒和胃肠道症状。
IF 2.5 3区 医学
International journal of sport nutrition and exercise metabolism Pub Date : 2023-01-01 DOI: 10.1123/ijsnem.2022-0083
Charles S Urwin, Rodney J Snow, Dominique Condo, Rhiannon M J Snipe, Glenn D Wadley, Lilia Convit, Amelia J Carr
{"title":"A Comparison of Sodium Citrate and Sodium Bicarbonate Ingestion: Blood Alkalosis and Gastrointestinal Symptoms.","authors":"Charles S Urwin,&nbsp;Rodney J Snow,&nbsp;Dominique Condo,&nbsp;Rhiannon M J Snipe,&nbsp;Glenn D Wadley,&nbsp;Lilia Convit,&nbsp;Amelia J Carr","doi":"10.1123/ijsnem.2022-0083","DOIUrl":"https://doi.org/10.1123/ijsnem.2022-0083","url":null,"abstract":"<p><p>This study compared the recommended dose of sodium citrate (SC, 500 mg/kg body mass) and sodium bicarbonate (SB, 300 mg/kg body mass) for blood alkalosis (blood [HCO3-]) and gastrointestinal symptoms (GIS; number and severity). Sixteen healthy individuals ingested the supplements in a randomized, crossover design. Gelatin capsules were ingested over 15 min alongside a carbohydrate-rich meal, after which participants remained seated for forearm venous blood sample collection and completion of GIS questionnaires every 30 min for 300 min. Time-course and session value (i.e., peak and time to peak) comparisons of SC and SB supplementation were performed using linear mixed models. Peak blood [HCO3-] was similar for SC (mean 34.2, 95% confidence intervals [33.4, 35.0] mmol/L) and SB (mean 33.6, 95% confidence intervals [32.8, 34.5] mmol/L, p = .308), as was delta blood [HCO3-] (SC = 7.9 mmol/L; SB = 7.3 mmol/L, p = .478). Blood [HCO3-] was ≥6 mmol/L above baseline from 180 to 240 min postingestion for SC, significantly later than for SB (120-180 min; p < .001). GIS were mostly minor, and peaked 80-90 min postingestion for SC, and 35-50 min postingestion for SB. There were no significant differences for the number or severity of GIS reported (p > .05 for all parameters). In summary, the recommended doses of SC and SB induce similar blood alkalosis and GIS, but with a different time course.</p>","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":"33 1","pages":"1-10"},"PeriodicalIF":2.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10451731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
For Flux Sake: Isotopic Tracer Methods of Monitoring Human Carbohydrate Metabolism During Exercise. 为了通量的目的:同位素示踪法监测运动期间人体碳水化合物代谢。
IF 2.5 3区 医学
International journal of sport nutrition and exercise metabolism Pub Date : 2023-01-01 DOI: 10.1123/ijsnem.2022-0170
Javier T Gonzalez, Andy J King
{"title":"For Flux Sake: Isotopic Tracer Methods of Monitoring Human Carbohydrate Metabolism During Exercise.","authors":"Javier T Gonzalez,&nbsp;Andy J King","doi":"10.1123/ijsnem.2022-0170","DOIUrl":"https://doi.org/10.1123/ijsnem.2022-0170","url":null,"abstract":"<p><p>Isotopic tracers can reveal insights into the temporal nature of metabolism and track the fate of ingested substrates. A common use of tracers is to assess aspects of human carbohydrate metabolism during exercise under various established models. The dilution model is used alongside intravenous infusion of tracers to assess carbohydrate appearance and disappearance rates in the circulation, which can be further delineated into exogenous and endogenous sources. The incorporation model can be used to estimate exogenous carbohydrate oxidation rates. Combining methods can provide insight into key factors regulating health and performance, such as muscle and liver glycogen utilization, and the underlying regulation of blood glucose homeostasis before, during, and after exercise. Obtaining accurate, quantifiable data from tracers, however, requires careful consideration of key methodological principles. These include appropriate standardization of pretrial diet, specific tracer choice, whether a background trial is necessary to correct expired breath CO2 enrichments, and if so, what the appropriate background trial should consist of. Researchers must also consider the intensity and pattern of exercise, and the type, amount, and frequency of feeding (if any). The rationale for these considerations is discussed, along with an experimental design checklist and equation list which aims to assist researchers in performing high-quality research on carbohydrate metabolism during exercise using isotopic tracer methods.</p>","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":"33 1","pages":"60-70"},"PeriodicalIF":2.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10428659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Acknowledgments 致谢。
IF 2.5 3区 医学
International journal of sport nutrition and exercise metabolism Pub Date : 2022-11-29 DOI: 10.1123/ijsnem.2022-0234
{"title":"Acknowledgments","authors":"","doi":"10.1123/ijsnem.2022-0234","DOIUrl":"https://doi.org/10.1123/ijsnem.2022-0234","url":null,"abstract":"Journal Name: International Journal of Sport Nutrition and Exercise Metabolism<br/>Volume: 33<br/>Issue: 1<br/>Pages: 71-71","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":"278 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2022-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138505605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Creatine Monohydrate Supplementation, but not Creatyl-L-Leucine, Increased Muscle Creatine Content in Healthy Young Adults: A Double-Blind Randomized Controlled Trial. 补充一水肌酸,而不是肌酸- l-亮氨酸,可增加健康年轻人肌肉肌酸含量:一项双盲随机对照试验
IF 2.5 3区 医学
International journal of sport nutrition and exercise metabolism Pub Date : 2022-11-01 DOI: 10.1123/ijsnem.2022-0074
Andrew T Askow, Kevin J M Paulussen, Colleen F McKenna, Amadeo F Salvador, Susannah E Scaroni, Jade S Hamann, Alexander V Ulanov, Zhong Li, Scott A Paluska, Kayleigh M Beaudry, Michael De Lisio, Nicholas A Burd
{"title":"Creatine Monohydrate Supplementation, but not Creatyl-L-Leucine, Increased Muscle Creatine Content in Healthy Young Adults: A Double-Blind Randomized Controlled Trial.","authors":"Andrew T Askow,&nbsp;Kevin J M Paulussen,&nbsp;Colleen F McKenna,&nbsp;Amadeo F Salvador,&nbsp;Susannah E Scaroni,&nbsp;Jade S Hamann,&nbsp;Alexander V Ulanov,&nbsp;Zhong Li,&nbsp;Scott A Paluska,&nbsp;Kayleigh M Beaudry,&nbsp;Michael De Lisio,&nbsp;Nicholas A Burd","doi":"10.1123/ijsnem.2022-0074","DOIUrl":"https://doi.org/10.1123/ijsnem.2022-0074","url":null,"abstract":"<p><p>Creatine (Cr) supplementation is a well-established strategy to enhance gains in strength, lean body mass, and power from a period of resistance training. However, the effectiveness of creatyl-L-leucine (CLL), a purported Cr amide, is unknown. Therefore, the purpose of this study was to assess the effects of CLL on muscle Cr content. Twenty-nine healthy men (n = 17) and women (n = 12) consumed 5 g/day of either Cr monohydrate (n = 8; 28.5 ± 7.3 years, 172.1 ± 11.0 cm, 76.6 ± 10.7 kg), CLL (n = 11; 29.2 ± 9.3 years, 170.3 ± 10.5 cm, 71.9 ± 14.5 kg), or placebo (n = 10; 30.3 ± 6.9 years, 167.8 ± 9.9 cm, 69.9 ± 11.1 kg) for 14 days in a randomized, double-blind design. Participants completed three bouts of supervised resistance exercise per week. Muscle biopsies were collected before and after the intervention for quantification of muscle Cr. Cr monohydrate supplementation which significantly increased muscle Cr content with 14 days of supplementation. No changes in muscle Cr were observed for the placebo or CLL groups. Cr monohydrate supplementation is an effective strategy to augment muscle Cr content while CLL is not.</p>","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":"32 6","pages":"446-452"},"PeriodicalIF":2.5,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9755768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Comment on: "Association of Vitamin D Supplementation in Cardiorespiratory Fitness and Muscle Strength in Adult Twins: A Randomized Controlled Trial". 评论:“补充维生素D与成年双胞胎心肺健康和肌肉力量的关系:一项随机对照试验”。
IF 3 3区 医学
International journal of sport nutrition and exercise metabolism Pub Date : 2022-06-01 Print Date: 2022-09-01 DOI: 10.1123/ijsnem.2022-0101
Nicholas B Tiller
{"title":"Comment on: \"Association of Vitamin D Supplementation in Cardiorespiratory Fitness and Muscle Strength in Adult Twins: A Randomized Controlled Trial\".","authors":"Nicholas B Tiller","doi":"10.1123/ijsnem.2022-0101","DOIUrl":"10.1123/ijsnem.2022-0101","url":null,"abstract":"","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":"61 1","pages":"419-420"},"PeriodicalIF":3.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84027648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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