International journal of sport nutrition and exercise metabolism最新文献_第3页

Effect of Menstrual Cycle Phase and Hormonal Contraceptives on Resting Metabolic Rate and Body Composition. 月经周期阶段和荷尔蒙避孕药对静息代谢率和身体成分的影响

IF 3 3区医学

International journal of sport nutrition and exercise metabolism Pub Date : 2024-04-23 Print Date: 2024-07-01 DOI: 10.1123/ijsnem.2023-0193

Megan A Kuikman, Alannah K A McKay, Clare Minahan, Rachel Harris, Kirsty J Elliott-Sale, Trent Stellingwerff, Ella S Smith, Rachel McCormick, Nicolin Tee, Jessica Skinner, Kathryn E Ackerman, Louise M Burke

{"title":"Effect of Menstrual Cycle Phase and Hormonal Contraceptives on Resting Metabolic Rate and Body Composition.","authors":"Megan A Kuikman, Alannah K A McKay, Clare Minahan, Rachel Harris, Kirsty J Elliott-Sale, Trent Stellingwerff, Ella S Smith, Rachel McCormick, Nicolin Tee, Jessica Skinner, Kathryn E Ackerman, Louise M Burke","doi":"10.1123/ijsnem.2023-0193","DOIUrl":"10.1123/ijsnem.2023-0193","url":null,"abstract":"The cyclical changes in sex hormones across the menstrual cycle (MC) are associated with various biological changes that may alter resting metabolic rate (RMR) and body composition estimates. Hormonal contraceptive (HC) use must also be considered given their impact on endogenous sex hormone concentrations and synchronous exogenous profiles. The purpose of this study was to determine if RMR and dual-energy X-ray absorptiometry body composition estimates change across the MC and differ compared with HC users. This was accomplished during a 5-week training camp involving naturally cycling athletes (n = 11) and HC users (n = 7 subdermal progestin implant, n = 4 combined monophasic oral contraceptive pill, n = 1 injection) from the National Rugby League Indigenous Women's Academy. MC phase was retrospectively confirmed via serum estradiol and progesterone concentrations and a positive ovulation test. HC users had serum estradiol and progesterone concentrations assessed at the time point of testing. Results were analyzed using general linear mixed model. There was no effect of MC phase on absolute RMR (p = .877), relative RMR (p = .957), or dual-energy X-ray absorptiometry body composition estimates (p > .05). There was no effect of HC use on absolute RMR (p = .069), relative RMR (p = .679), or fat mass estimates (p = .766), but HC users had a greater fat-free mass and lean body mass than naturally cycling athletes (p = .028). Our findings suggest that RMR and dual-energy X-ray absorptiometry body composition estimates do not significantly differ due to changes in sex hormones in a group of athletes, and measurements can be compared between MC phases or with HC usage without variations in sex hormones causing additional noise.","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":" ","pages":"207-217"},"PeriodicalIF":3.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140865174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Caffeine, but Not Creatine, Improves Anaerobic Power Without Altering Anaerobic Capacity in Healthy Men During a Wingate Anaerobic Test. 咖啡因（而非肌酸）能提高健康男性在 Wingate 无氧测试中的无氧功率，但不会改变其无氧能力。

IF 2.5 3区医学

International journal of sport nutrition and exercise metabolism Pub Date : 2024-03-07 Print Date: 2024-05-01 DOI: 10.1123/ijsnem.2023-0191

Alisson Henrique Marinho, Marcos David Silva-Cavalcante, Gislaine Cristina-Souza, Filipe Antonio de Barros Sousa, Thays Ataide-Silva, Romulo Bertuzzi, Gustavo Gomes de Araujo, Adriano Eduardo Lima-Silva

{"title":"Caffeine, but Not Creatine, Improves Anaerobic Power Without Altering Anaerobic Capacity in Healthy Men During a Wingate Anaerobic Test.","authors":"Alisson Henrique Marinho, Marcos David Silva-Cavalcante, Gislaine Cristina-Souza, Filipe Antonio de Barros Sousa, Thays Ataide-Silva, Romulo Bertuzzi, Gustavo Gomes de Araujo, Adriano Eduardo Lima-Silva","doi":"10.1123/ijsnem.2023-0191","DOIUrl":"10.1123/ijsnem.2023-0191","url":null,"abstract":"There is a lack of evidence on the additional benefits of combining caffeine (CAF) and creatine (CRE) supplementation on anaerobic power and capacity. Thus, the aim of the present study was to test the effects of combined and isolated supplementation of CAF and CRE on anaerobic power and capacity. Twenty-four healthy men performed a baseline Wingate anaerobic test and were then allocated into a CRE (n = 12) or placebo (PLA; n = 12) group. The CRE group ingested 20 g/day of CRE for 8 days, while the PLA group ingested 20 g/day of maltodextrin for the same period. On the sixth and eighth days of the loading period, both groups performed a Wingate anaerobic test 1 hr after either CAF (5 mg/kg of body mass; CRE + CAF and PLA + CAF conditions) or PLA (5 mg/kg of body mass of cellulose; CRE + PLA and PLA + PLA conditions) ingestion. After the loading period, changes in body mass were greater (p < .05) in the CRE (+0.87 ± 0.23 kg) than in the PLA group (+0.13 ± 0.27 kg). In both groups, peak power was higher (p = .01) in the CAF (1,033.4 ± 209.3 W) than in the PLA trial (1,003.3 ± 204.4 W), but mean power was not different between PLA and CAF trials (p > .05). In conclusion, CAF, but not CRE ingestion, increases anaerobic power. Conversely, neither CRE nor CAF has an effect on anaerobic capacity.","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":" ","pages":"137-144"},"PeriodicalIF":2.5,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140065105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trehalose Improved 20-min Cycling Time-Trial Performance After 100-min Cycling in Amateur Cyclists. 在业余自行车运动员进行 100 分钟自行车运动后，特利哈糖可提高他们的 20 分钟自行车计时赛成绩。

IF 3 3区医学

International journal of sport nutrition and exercise metabolism Pub Date : 2024-03-07 Print Date: 2024-07-01 DOI: 10.1123/ijsnem.2023-0241

Nathan Gobbi de Oliveira, Luana Farias de Oliveira, Rafael Pires da Silva, Tamires Nunes Oliveira, Gabriella Berwig Möller, Juliana Murasaki, Manoel Antônio Ramires, Rafael de Almeida Azevedo, Guilherme Giannini Artioli, Hamilton Roschel, Bruno Gualano, Bryan Saunders

{"title":"Trehalose Improved 20-min Cycling Time-Trial Performance After 100-min Cycling in Amateur Cyclists.","authors":"Nathan Gobbi de Oliveira, Luana Farias de Oliveira, Rafael Pires da Silva, Tamires Nunes Oliveira, Gabriella Berwig Möller, Juliana Murasaki, Manoel Antônio Ramires, Rafael de Almeida Azevedo, Guilherme Giannini Artioli, Hamilton Roschel, Bruno Gualano, Bryan Saunders","doi":"10.1123/ijsnem.2023-0241","DOIUrl":"10.1123/ijsnem.2023-0241","url":null,"abstract":"Carbohydrate (CHO) supplementation during endurance exercise can improve performance. However, it is unclear whether low glycemic index (GI) CHO leads to differential ergogenic and metabolic effects compared with a standard high GI CHO. This study investigated the ergogenic and metabolic effects of CHO supplementation with distinct GIs, namely, (a) trehalose (30 g/hr), (b) isomaltulose (30 g/hr), (c) maltodextrin (60 g/hr), and (d) placebo (water). In this double-blind, crossover, counterbalanced, placebo-controlled study, 13 male cyclists cycled a total of 100 min at varied exercise intensity (i.e., 10-min stages at 1.5, 2.0, and 2.5 W/kg; repeated three times plus two 5-min stages at 1.0 W/kg before and after the protocol), followed by a 20-min time trial on four separated occasions. Blood glucose and lactate (every 20 min), heart rate, and ratings of perceived exertion were collected throughout, and muscle biopsies were taken before and immediately after exercise. The results showed that trehalose improved time-trial performance compared with placebo (total work done 302 ± 39 vs. 287 ± 48 kJ; p = .01), with no other differences between sessions (all p ≥ .07). Throughout the 100-min protocol, blood glucose was higher with maltodextrin compared with the other supplements at all time points (all p < .05). Heart rate, ratings of perceived exertion, muscle glycogen content, blood glucose, and lactate were not different between conditions when considering the 20-min time trial (all p > .05). Trehalose supplementation throughout endurance exercise improved cycling performance and appears to be an appropriate CHO source for exercise tasks up to 2 hr. No ergogenic superiority between the different types of CHO was established.","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":" ","pages":"199-206"},"PeriodicalIF":3.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140065106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cold Ambient Temperature Does Not Alter Subcutaneous Abdominal Adipose Tissue Lipolysis and Blood Flow in Endurance-Trained Cyclists. 低温环境不会改变耐力训练自行车运动员的皮下腹部脂肪组织脂肪分解和血流量。

IF 2.5 3区医学

International journal of sport nutrition and exercise metabolism Pub Date : 2024-02-08 Print Date: 2024-05-01 DOI: 10.1123/ijsnem.2023-0150

Christopher W Bach, Patrick G Saracino, Daniel A Baur, Brandon D Willingham, Brent C Ruby, Michael J Ormsbee

{"title":"Cold Ambient Temperature Does Not Alter Subcutaneous Abdominal Adipose Tissue Lipolysis and Blood Flow in Endurance-Trained Cyclists.","authors":"Christopher W Bach, Patrick G Saracino, Daniel A Baur, Brandon D Willingham, Brent C Ruby, Michael J Ormsbee","doi":"10.1123/ijsnem.2023-0150","DOIUrl":"10.1123/ijsnem.2023-0150","url":null,"abstract":"This study sought to investigate the effect of cold ambient temperature on subcutaneous abdominal adipose tissue (SCAAT) lipolysis and blood flow during steady-state endurance exercise in endurance-trained cyclists. Ten males (age: 23 ± 3 years; peak oxygen consumption: 60.60 ± 4.84 ml·kg-1·min-1; body fat: 18.4% ± 3.5%) participated in baseline lactate threshold (LT) and peak oxygen consumption testing, two familiarization trials, and two experimental trials. Experimental trials consisted of cycling in COLD (3 °C; 42% relative humidity) and neutral (NEU; 19 °C; 39% relative humidity) temperatures. Exercise consisted of 25 min cycling at 70% LT and 25 min at 90% LT. In situ SCAAT lipolysis and blood flow were measured via microdialysis. Heart rate, core temperature, carbohydrate and fat oxidation, blood glucose, and blood lactate were also measured. Heart rate, core temperature, oxygen consumption, and blood lactate increased with exercise but were not different between COLD and NEU. SCAAT blood flow did not change from rest to exercise or between COLD and NEU. Interstitial glycerol increased during exercise (p < .001) with no difference between COLD and NEU. Fat oxidation increased (p < .001) at the onset of exercise and remained elevated thereafter with no difference between COLD and NEU. Carbohydrate oxidation increased with increasing exercise intensity and was greater at 70% LT in COLD compared to NEU (p = .030). No differences were observed between conditions for any other variable. Cycling exercise increased SCAAT lipolysis but not blood flow. Ambient temperature did not alter SCAAT metabolism, SCAAT blood flow, or fat oxidation in well-trained cyclists, though cold exposure increased whole-body carbohydrate oxidation at lower exercise intensities.","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":" ","pages":"145-153"},"PeriodicalIF":2.5,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139706642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Energy Expenditure of Elite Male and Female Professional Tennis Players During Habitual Training. 职业网球男女精英运动员在习惯性训练中的能量消耗。

IF 2.5 3区医学

International journal of sport nutrition and exercise metabolism Pub Date : 2024-01-27 Print Date: 2024-05-01 DOI: 10.1123/ijsnem.2023-0197

Daniel G Ellis, James P Morton, Graeme L Close, Tim F Donovan

{"title":"Energy Expenditure of Elite Male and Female Professional Tennis Players During Habitual Training.","authors":"Daniel G Ellis, James P Morton, Graeme L Close, Tim F Donovan","doi":"10.1123/ijsnem.2023-0197","DOIUrl":"10.1123/ijsnem.2023-0197","url":null,"abstract":"Understanding the daily energy expenditure of athletes during training is important to support recovery, adaptation, and the maintenance of performance. The aim of the current research was to assess the total daily energy expenditure (TDEE) and the acute energy expenditure (EE) of tennis training sessions during habitual training of elite tennis players. Using a cohort study design, 27 (n = 10, male; age; 22.3 ± 3.2 years and n = 17, female; age: 23.8 ± 3.5 years) elite singles tennis players were assessed for TDEE and tennis training EE. Using Actiheart activity monitors during a 2- to 5-day training period, male players were analyzed for 26 days and 33 (1.3 ± 0.5 sessions/day) tennis training sessions, and female players for 43 days and 58 (1.2 ± 0.4 sessions/day) tennis training sessions. Male TDEE (4,708 ± 583 kcal/day) was significantly higher than female (3,639 ± 305 kcal/day). Male absolute and relative tennis training EEs (10.2 ± 2.3 kcal/min and 7.9 ± 1.4 kcal·hr-1·kg-1) were significantly higher than those of females (7.6 ± 1.0 kcal/min and 6.8 ± 0.9 kcal·hr-1·kg-1). The resting metabolic rate was assessed via indirect calorimetry. The physical activity level for both groups was 2.3 AU. The TDEE of male and female players during habitual training now highlights the continual cycle of high energy demands experienced by the elite tennis player. The broad ranges of TDEE and EE reported here suggest individual assessment and nutritional planning be prioritized, with a particular focus on carbohydrate requirements.","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":" ","pages":"172-178"},"PeriodicalIF":2.5,"publicationDate":"2024-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139570174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Timing of Caffeine Ingestion Does Not Improve Three-Point Shooting Accuracy in College Basketball Players. 摄入咖啡因的时机并不能提高大学篮球运动员的三分球命中率

IF 2.5 3区医学

International journal of sport nutrition and exercise metabolism Pub Date : 2024-01-24 Print Date: 2024-05-01 DOI: 10.1123/ijsnem.2023-0217

Zhi Sen Tan, Rachelle Yahn Yee Sim, Masato Kawabata, Dorrain Yanwen Low, Yulan Wang, Stephen F Burns

{"title":"Timing of Caffeine Ingestion Does Not Improve Three-Point Shooting Accuracy in College Basketball Players.","authors":"Zhi Sen Tan, Rachelle Yahn Yee Sim, Masato Kawabata, Dorrain Yanwen Low, Yulan Wang, Stephen F Burns","doi":"10.1123/ijsnem.2023-0217","DOIUrl":"10.1123/ijsnem.2023-0217","url":null,"abstract":"This study investigated the effects of the timing of caffeine (3 mg/kg body mass) ingestion on three-point shooting accuracy and other performance parameters during a basketball exercise simulation test (BEST). Eighteen college basketball players (mean ± SD: age = 24.4 ± 1.5 years, height = 181.7 ± 9.5 cm, body mass = 80.9 ± 13.2 kg) underwent one familiarization trial and three main conditions in a randomized order: (a) placebo (maltodextrin) and placebo, (b) caffeine and placebo, and (c) placebo and caffeine. Participants ingested either the placebo or caffeine pill 75 and 15 min before performing four quarters of the BEST and a three-point shooting protocol. During each quarter, participants completed 16 rounds of the BEST and ten three-point shots. Vertical jump height, 6 m sprint timing, BEST completion timing, three-point shooting accuracy, heart rate, rate of perceived exertion, blood glucose, blood lactate, and psychological measures pertaining to performance were measured. The BEST completion timing differed among conditions (placebo and placebo = 26.4 ± 2.0 s, caffeine and placebo = 25.8 ± 2.0 s, placebo and caffeine = 25.9 ± 2.1 s; p = .031) but not three-point shooting accuracy (placebo and placebo = 12.33 ± 4.10; caffeine and placebo = 12.61 ± 2.81; placebo and caffeine = 11.67 ± 3.77; p = .648), vertical jump height, or sprint times. Manipulating ingestion timing of caffeine did not improve three-point shooting accuracy, vertical jump height, or 6 m sprint timings, but caffeine can improve performance times during simulated basketball exercise irrespective of ingestion timing.","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":" ","pages":"154-163"},"PeriodicalIF":2.5,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139546498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Caffeine Does Not Alter Performance, Perceptual Responses, and Oxidative Stress After Short Sprint Interval Training. 咖啡因不会改变短距离冲刺间歇训练后的表现、知觉反应和氧化应激。

IF 2.5 3区医学

International journal of sport nutrition and exercise metabolism Pub Date : 2024-01-24 Print Date: 2024-05-01 DOI: 10.1123/ijsnem.2023-0170

Mauro F Bernardo, Alysson Enes, Elisangela F Rezende, Alexandre R Okuyama, Ragami C Alves, Murilo de Andrade, Ana Carolina G Macedo, Marcelo Paes de Barros, Darren G Candow, Scott C Forbes, Tácito P Souza-Junior

{"title":"Caffeine Does Not Alter Performance, Perceptual Responses, and Oxidative Stress After Short Sprint Interval Training.","authors":"Mauro F Bernardo, Alysson Enes, Elisangela F Rezende, Alexandre R Okuyama, Ragami C Alves, Murilo de Andrade, Ana Carolina G Macedo, Marcelo Paes de Barros, Darren G Candow, Scott C Forbes, Tácito P Souza-Junior","doi":"10.1123/ijsnem.2023-0170","DOIUrl":"10.1123/ijsnem.2023-0170","url":null,"abstract":"Despite the abundance of research investigating the efficacy of caffeine supplementation on exercise performance, the physiological and biochemical responses to caffeine supplementation during intermittent activities are less evident. This study investigated the acute effects of caffeine supplementation on measures of exercise performance, ratings of perceived exertion, and biomarkers of oxidative stress induced by an acute bout of sprint interval training. In a randomized crossover design, 12 healthy males (age: 26 ± 4 years, height: 177.5 ± 6 cm, body mass: 80.7 ± 7.6 kg) ingested 6 mg/kg of caffeine or placebo 60 min prior to performing sprint interval training (12 × 6 s \"all-out sprints\" interspersed by 60 s of rest). Performance scores and ratings of perceived exertion were assessed after every sprint. Blood samples were collected before supplementation, prior to and following each sprint, and 5 and 60 min after the last sprint. Caffeine had no effect on any performance measures, ratings of perceived exertion, or biomarkers of oxidative stress (p > .05). In conclusion, caffeine supplementation does not improve performance or decrease oxidative stress after an acute bout of sprint interval training.","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":" ","pages":"179-187"},"PeriodicalIF":2.5,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139546495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute Beetroot Juice Supplementation Has No Effect on Upper- and Lower-Body Maximal Isokinetic Strength and Muscular Endurance in International-Level Male Gymnasts. 急性补充甜菜根汁对国际级男子体操运动员的上下肢最大等速力量和肌肉耐力没有影响。

IF 2.5 3区医学

International journal of sport nutrition and exercise metabolism Pub Date : 2024-01-18 Print Date: 2024-05-01 DOI: 10.1123/ijsnem.2023-0202

Ozcan Esen, Joseph Fox, Raci Karayigit, Ian Walshe

{"title":"Acute Beetroot Juice Supplementation Has No Effect on Upper- and Lower-Body Maximal Isokinetic Strength and Muscular Endurance in International-Level Male Gymnasts.","authors":"Ozcan Esen, Joseph Fox, Raci Karayigit, Ian Walshe","doi":"10.1123/ijsnem.2023-0202","DOIUrl":"10.1123/ijsnem.2023-0202","url":null,"abstract":"Nitrate (NO3-) has properties that can improve muscle function, leading to improvements in metabolic cost of exercise as well as enhance force production. Gymnastics is a whole-body sport, involving events that demand a high level of strength and fatigue resistance. However, the effect of NO3- supplementation on both upper- and lower-body function in gymnasts is unknown. This study examined the effect of acute beetroot juice (BRJ) supplementation on isokinetic strength and endurance of the upper- and lower-body in highly trained international-level male gymnasts. In a double-blind, randomized crossover design, 10 international-level male gymnasts completed two acute supplementation periods, consuming either 2 × 70 ml NO3--rich (∼12.8 mmol/L of NO3-) or NO3--depleted (PLA) BRJ. Maximal strength of the upper-leg and upper-arm at 60°/s, 120°/s, 180°/s, and 300°/s, and muscular endurance (50 repeated isokinetic contractions at 180°/s) were assessed. Plasma NO3- (BRJ: 663 ± 164 μM, PLA: 89 ± 48 μM) and nitrite (NO2-) concentrations (BRJ: 410 ± 137 nmol/L, PLA: 125 ± 36 nmol/L) were elevated following BRJ compared to PLA (both p < .001). Maximal strength of knee and elbow extensors and flexors did not differ between supplements (p > .05 for all velocities). Similarly, fatigue index of knee and elbow extension and flexion was not different between supplements (all p > .05). Acute BRJ supplementation, containing ∼12.8 mmol/L of NO3-, increased plasma NO3- and NO2- concentrations, but did not enhance isokinetic strength or fatigue resistance of either upper or lower extremities in international-level male gymnasts.","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":" ","pages":"164-171"},"PeriodicalIF":2.5,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139490913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pharmacokinetic Profile of Caffeine and Its Two Main Metabolites in Dried Blood Spots After Five Different Oral Caffeine Administration Forms-A Randomized Crossover Study. 咖啡因及其两种主要代谢物在五种不同咖啡因口服给药形式下干燥血斑中的药代动力学特征--随机交叉研究

IF 3 3区医学

International journal of sport nutrition and exercise metabolism Pub Date : 2024-01-12 Print Date: 2024-03-01 DOI: 10.1123/ijsnem.2023-0141

Chiara Tuma, Andreas Thomas, Lasse Trede, Hans Braun, Mario Thevis

{"title":"Pharmacokinetic Profile of Caffeine and Its Two Main Metabolites in Dried Blood Spots After Five Different Oral Caffeine Administration Forms-A Randomized Crossover Study.","authors":"Chiara Tuma, Andreas Thomas, Lasse Trede, Hans Braun, Mario Thevis","doi":"10.1123/ijsnem.2023-0141","DOIUrl":"10.1123/ijsnem.2023-0141","url":null,"abstract":"Caffeine is an ergogenic substance that is consumed globally in many forms. The use of buccally absorbable formulations instead of gastrointestinal uptake has become increasingly popular over the years, especially when accelerated absorption with minimal gastrointestinal stress is desired. This study investigated the impact of five different formulations and administration routes of caffeine on the whole blood concentrations of caffeine, paraxanthine, and theobromine: caffeinated capsules, tablets, shots, pouches, and chewing gums. A uniform dose of caffeine (200 mg) was administered to 16 healthy recreational athletes (26.0 ± 2.1 years) using a randomized crossover design. Samples were taken in the form of dried blood spots at 16 different time points in a 2-hr timeframe after drug administration. The samples were analyzed using a validated liquid chromatography-tandem mass spectrometry method. The results for caffeine showed no significant differences in the overall bioavailability (area under the concentration-time curve), maximal concentration, and time to maximum concentration. However, when analyzing the bioavailability of caffeine in the first 5, 10, and 15 min, the liquid caffeine formulation was superior to other administered forms (p < .05). This indicates that caffeine solubility has a major influence on its absorption rate. In sports, the rate of caffeine absorption must be considered, not only when ingesting anhydrous caffeine, but also when choosing buccal absorption. These findings imply that general guidelines for ergogenic caffeine use should consider the formulation used and, accordingly, the corresponding route of absorption.","PeriodicalId":14334,"journal":{"name":"International journal of sport nutrition and exercise metabolism","volume":" ","pages":"101-110"},"PeriodicalIF":3.0,"publicationDate":"2024-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139432270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acknowledgments 致谢

IF 2.5 3区医学

International journal of sport nutrition and exercise metabolism Pub Date : 2023-11-29 DOI: 10.1123/ijsnem.2023-0240

引用次数: 0