International Journal of Research in Dermatology最新文献_第9页

Repigmentation of vitiligo universalis masquerading as pseudo-melasma

International Journal of Research in Dermatology Pub Date : 2023-06-26 DOI: 10.18203/issn.2455-4529.intjresdermatol20231831

Bushra Muna, Srikanth Shanmugam

引用次数: 0

The association of cytosine-adenine-guanine repeat polymorphism in the androgen receptor gene with nodulocystic acne in Egyptian patients 雄激素受体基因中胞嘧啶-腺嘌呤-鸟嘌呤重复多态性与埃及患者结节性痤疮的关系

International Journal of Research in Dermatology Pub Date : 2023-06-26 DOI: 10.18203/issn.2455-4529.intjresdermatol20231823

Nehal M. Zuelfakkar, N. Ragab, A. Shehab, Momena Nagy

{"title":"The association of cytosine-adenine-guanine repeat polymorphism in the androgen receptor gene with nodulocystic acne in Egyptian patients","authors":"Nehal M. Zuelfakkar, N. Ragab, A. Shehab, Momena Nagy","doi":"10.18203/issn.2455-4529.intjresdermatol20231823","DOIUrl":"https://doi.org/10.18203/issn.2455-4529.intjresdermatol20231823","url":null,"abstract":"Background: The role of androgens in acne pathophysiology has been supported by long-standing clinical and experimental observations.\u0000Methods: Genotyping for the androgen receptor gene was performed by PCR-based fragment length analysis, aiming to investigate cytosine-adenine-guanine (CAG) repeat polymorphism in Egyptian nodulocystic acne patients to clarify its relevance to the pathogenesis. Detailed frequency of CAG repeats number in patients and control groups, in 25 males and 25 females and Comparison of CAG repeat number regarding demographic and clinical characteristics was performed.\u0000Results: It was found that females had a higher frequency of longer CAG repeats compared to males, while in control group there was an even distribution of CAG number repeats in both females and males. Male and female acne patients had significantly lower number of CAG repeats compared to controls with statistically significant difference (p≤0.05). Comparison of CAG repeat number regarding demographic and clinical characteristics revealed no significant correlation or association with patients’ age, duration of acne, onset or course of the disease.\u0000Conclusions: These findings support the hypothesis that CAG repeats number affects AR activity, therefore, acne development and severity. Moreover, analysis of CAG repeats number in acne patients can be of considerable importance in the treatment strategy, indicating the role of antiandrogen therapy in acne patients.","PeriodicalId":14331,"journal":{"name":"International Journal of Research in Dermatology","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75267570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of metabolic syndrome and insulin resistance in papulosquamous diseases 丘疹鳞状病变代谢综合征与胰岛素抵抗的关系

International Journal of Research in Dermatology Pub Date : 2023-06-26 DOI: 10.18203/issn.2455-4529.intjresdermatol20231826

Abhineetha Hosthota, I. U., Anila Sara Thampi, S. R, Chaganam Kavya, Chandan B. C., Bhavana Venumbaka

{"title":"Association of metabolic syndrome and insulin resistance in papulosquamous diseases","authors":"Abhineetha Hosthota, I. U., Anila Sara Thampi, S. R, Chaganam Kavya, Chandan B. C., Bhavana Venumbaka","doi":"10.18203/issn.2455-4529.intjresdermatol20231826","DOIUrl":"https://doi.org/10.18203/issn.2455-4529.intjresdermatol20231826","url":null,"abstract":"Background: Metabolic syndrome (MetS), insulin resistance (IR) and papulosquamous diseases with shared pathophysiology leads to conglomeration of risk factors of non-communicable diseases like cardiovascular disease (CVD) and type 2 diabetes (T2D) causing high mortality worldwide. The objective is to study the association of MetS and IR in papulosquamous diseases.\u0000Methods: It is a hospital-based case-control study conducted on 200 age-sex matched cases and controls with consent. Subjects were administered a pre-validated questionnaire, diagnosis of papulosquamous diseases was based on clinical examination and skin biopsy. MetS was diagnosed based on national cholesterol education program's- adult treatment plan iii with Asian modification for abdominal circumference criteria. Fasting serum insulin levels (FI) was used as a surrogate marker of IR. \u0000Results: Mean serum HDL- C level was low and statistically significant (p=0.017). Mean fasting plasma glucose level was significantly higher in patients (p=0.008). Mean FI level was significant between cases and controls (p=0.013). IR was found in 76% of cases which was significantly higher than in controls (p<0.05). IR was highest in psoriasis 29% followed by LP 22%, PRP 19%, and LS 6% which was statistically significant (p<0.05). MetS was mostly found in psoriasis (17%), LP (9%) and least in PRP, LS.\u0000Conclusions: This study intends clinicians to do periodic MetS and IR evaluation in papulosquamous diseases. Thus, subclinical cases of non-communicable diseases can be detected and potential co-morbidities can be prevented.","PeriodicalId":14331,"journal":{"name":"International Journal of Research in Dermatology","volume":"130 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80705823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A real-world data analysis on the usage of paraphenylenediamine and ammonia free hair dye 对苯二胺和无氨染发剂使用情况的真实数据分析

International Journal of Research in Dermatology Pub Date : 2023-06-20 DOI: 10.18203/issn.2455-4529.intjresdermatol20231795

M. Chatterjee, Vijayajyothi Mallela, Gaurav Bhaskar, Vidya T. S., Bhagyashree Mohod, Ashok Jaiswal

{"title":"A real-world data analysis on the usage of paraphenylenediamine and ammonia free hair dye","authors":"M. Chatterjee, Vijayajyothi Mallela, Gaurav Bhaskar, Vidya T. S., Bhagyashree Mohod, Ashok Jaiswal","doi":"10.18203/issn.2455-4529.intjresdermatol20231795","DOIUrl":"https://doi.org/10.18203/issn.2455-4529.intjresdermatol20231795","url":null,"abstract":"Background: Dyeing of hair for various reasons is a common practice across a broad age group. Most hair dyes available in the market contain para-phenylenediamine (PPD) and/or ammonia, which are proven skin and scalp irritants. A quest for better tolerable hair dyes has led to emergence of toluene-2, 5-diamine sulfate (TDS) and monoethanolamine (MEA), as a substitute to PPD and ammonia, respectively.\u0000Methods: This retrospective study was conducted on 35 participants from four centers across India to evaluate the efficacy, and tolerance of ammonia-free and PPD-free permanent hair dye.\u0000Results: A PPD-free and ammonia-free cream-based hair dye showed promising results. The color uptake following 35 minutes of application was 100% in 54.2% of the participants. The color retention was more than 95% in 74.3% participants after 8-10 shampoo washes. The adverse effects were noted to be markedly less with only a few cases experiencing itching. The participants' feedback obtained showed a conclusively high satisfaction rate. The Physicians' assessment of efficacy and safety recorded favorable scores.\u0000Conclusions: A TDS and MEA based cream hair color can be an effective and safe alternative to PPD and ammonia-based hair dye.","PeriodicalId":14331,"journal":{"name":"International Journal of Research in Dermatology","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88804561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of long pulse neodymium-doped yttrium aluminium garnet 1064 laser permanent hair reduction treatment in skin types V and VI Nigerian patients 长脉冲掺钕钇铝石榴石1064激光永久性脱毛治疗皮肤V型和VI型尼日利亚患者的疗效

International Journal of Research in Dermatology Pub Date : 2023-04-27 DOI: 10.18203/issn.2455-4529.intjresdermatol20231159

E. Anaba, Babawale Arabambi

{"title":"Efficacy of long pulse neodymium-doped yttrium aluminium garnet 1064 laser permanent hair reduction treatment in skin types V and VI Nigerian patients","authors":"E. Anaba, Babawale Arabambi","doi":"10.18203/issn.2455-4529.intjresdermatol20231159","DOIUrl":"https://doi.org/10.18203/issn.2455-4529.intjresdermatol20231159","url":null,"abstract":"Background: There are no studies examining the use, safety, efficacy, effective fluence and pulse duration of Laser hair reduction in Nigerians. This study aimed to document the safety, efficacy, effective fluence and pulse duration, and the number of Laser sessions to achieve permanent hair reduction.\u0000Methods: A retrospective review of Laser hair removal in 87 FitzPatrick skin type V and VI patients from January 2017 to August 2021 using the neodymium-doped yttrium aluminium garnet (Nd:Yag). The fluence (Joules/cm3), pulse duration (msecs), Laser site and interval between Laser sessions were documented. Data was summarized using frequencies and percentage proportion. Comparison of pulse duration, fluence, and the number of sessions between different body sites was tested using analysis of variance.\u0000Results: A total of 354 laser sessions were performed in 87 patients made up of 80 females and 7 males; mean age of 35.8±9.24 years. The face was the most frequently treated site (67.5% of the sessions). The mean number of laser sessions, pulse duration and fluence were 4.07±4.22, 19.38±1.48 (msec) and 18.22±1.29 (J/cm3) respectively. An average of 6 sessions was required to achieve permanent hair reduction: the face required a significantly lower number of sessions, p=0.043.\u0000Conclusions: The long pulse Nd:Yag 1064 laser is an effective and safe Laser for hair removal in skin types V and VI. The effective, safe pulse duration and fluence are 16 to 22 msec and 15 to 20 J/cm2 respectively. The face requires fewer number of Laser sessions.","PeriodicalId":14331,"journal":{"name":"International Journal of Research in Dermatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76578224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An institution-based non-randomised prospective study to estimate the efficacy and adverse effect profile of apremilast for moderate to severe refractory palmoplantar psoriasis 一项基于机构的非随机前瞻性研究，旨在评估阿普米司特治疗中度至重度难治性掌跖牛皮癣的疗效和不良反应

International Journal of Research in Dermatology Pub Date : 2023-04-27 DOI: 10.18203/issn.2455-4529.intjresdermatol20231163

N. Agrawal, Sabina Liangom Joanna Rongong, S. Halder, J. Barua, Param Satsangi, A. Halder, Prabal Samanta

{"title":"An institution-based non-randomised prospective study to estimate the efficacy and adverse effect profile of apremilast for moderate to severe refractory palmoplantar psoriasis","authors":"N. Agrawal, Sabina Liangom Joanna Rongong, S. Halder, J. Barua, Param Satsangi, A. Halder, Prabal Samanta","doi":"10.18203/issn.2455-4529.intjresdermatol20231163","DOIUrl":"https://doi.org/10.18203/issn.2455-4529.intjresdermatol20231163","url":null,"abstract":"Background: Psoriasis is an immune-mediated inflammatory papulo-squamous disorder presenting as chronic plaque, pustular, erythrodermic, nail, scalp, drug induced, inverse, guttate etc. Palmoplantar psoriasis causes significant functional, cosmetic and psychological disability. Apremilast is a relatively newer drug being PDE-4 inhibitor, having negligible adverse effects with minimum blood monitoring.\u0000Methods: It is an institution-based, non-randomised, prospective study conducted over a period of 3 months. 42 patients of moderate to severe disease (assessed using PPPASI), refractory to conventional line of therapy (for atleast 3 months) or had contraindications for the same were selected from our Dermatology OPD. Follow up was done monthly for 6 months.\u0000Results: 42% of the patients were good responders. 1 patient did not respond and 2 had progression of the disease. There was a decrease in the mean DLQI from a baseline of 25 to less than 15 by the end of 1st month and around 5 by the end of 6th month.60% of patients showed onset of response by the 1st month. 45% of the patients showed adverse effects, mostly being nausea followed by dizziness.\u0000Conclusions: From our study and those in the existing literature, it can be inferred that apremilast is a promising drug for palmoplantar as well as other forms of psoriasis, especially in patients with comorbidities or treatment refractory psoriasis.","PeriodicalId":14331,"journal":{"name":"International Journal of Research in Dermatology","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85816300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of atopic dermatitis in children in the city of Goma (Democratic Republic of Congo) 戈马市(刚果民主共和国)儿童特应性皮炎患病率

International Journal of Research in Dermatology Pub Date : 2023-04-27 DOI: 10.18203/issn.2455-4529.intjresdermatol20231160

N. Pascaline, Ndayazi B. Désiré, Atadokpèdé F., Wembonyama O. Stanis

{"title":"Prevalence of atopic dermatitis in children in the city of Goma (Democratic Republic of Congo)","authors":"N. Pascaline, Ndayazi B. Désiré, Atadokpèdé F., Wembonyama O. Stanis","doi":"10.18203/issn.2455-4529.intjresdermatol20231160","DOIUrl":"https://doi.org/10.18203/issn.2455-4529.intjresdermatol20231160","url":null,"abstract":"Background: Currently, atopic dermatitis is one of the most common chronic inflammatory dermatoses. However, studies concerning its prevalence in children are rare in the Democratic Republic of Congo (DRC). Thus, we proposed to determine the prevalence and sociodemographic factors associated with atopic dermatitis in children.\u0000Methods: We conducted a descriptive cross-sectional study over a 6-month period from June 1 to December 31, 2022. It focused on children aged 0 to 18 years who were brought to the dermatology services of the North Kivu Provincial Hospital (HPNK) for atopic dermatitis. Data were entered and analyzed using SPSS 20 and Epi info 3.5.3 software.\u0000Results: The hospital prevalence of atopic dermatitis in children aged 0-18 years was 12.4%. The 0 to 4 age group was the most affected with 54.4%. Males were the most represented (56.7%). The sex ratio M/F was 1.3. The majority of our patients were from the urban area (72.8%). Atopy (personal or familial) was found in 68.9% of patients and was dominated by asthma (23.9%) and allergic rhinitis (21.1%). The most common trigger was food (30.7%) followed by cosmetics (20.5%). Mean age of symptom onset was 7±2 months. The most represented clinical form was the common or vulgar form with 69.4% of cases. Atopic dermatitis was associated with sleep disorder in 77.8% of cases.\u0000Conclusions: The data presented in our study are also consistent with the literature which states that the prevalence of atopic dermatitis in children ranged from 10 to 20% and was higher in children under 5 years of age living in urban areas.","PeriodicalId":14331,"journal":{"name":"International Journal of Research in Dermatology","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88808571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lupus vulgaris on face: a case report 面部寻常性狼疮1例报告

International Journal of Research in Dermatology Pub Date : 2023-04-27 DOI: 10.18203/issn.2455-4529.intjresdermatol20231169

T. Nandakishore, Mrudula S., Linda Kongbam, Chai E. Buchem, Moirangthem Rokita, Anurag Srivastava

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Folliculitis barbae caused by Staphylococcus lentus: a rarity with its dermoscopy features 由葡萄球菌引起的巴巴性毛囊炎:一种罕见的皮肤镜检查特征

International Journal of Research in Dermatology Pub Date : 2023-04-27 DOI: 10.18203/issn.2455-4529.intjresdermatol20231168

B. Ankad, Sankappanavar V. Smitha, B. Nikam, A. Janagond

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A pediatric case of resistant lichen planus pigmentosus treated with colchicine 秋水仙碱治疗顽固性色素扁平苔藓1例

International Journal of Research in Dermatology Pub Date : 2023-04-27 DOI: 10.18203/issn.2455-4529.intjresdermatol20231164

Mehsas Zoubida, Sektaoui Soukaina, Boubnane Ibtissam, Znati Kaoutar, Senouci Karima, B. Laila

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