Vishal Sharma, Bobby John, Max K Shibu, Navpreet Singh
{"title":"Trajectory of functional recovery and health-related quality of life following multilevel soft-tissue surgery in children with spastic diplegic cerebral palsy: a prospective longitudinal observational study.","authors":"Vishal Sharma, Bobby John, Max K Shibu, Navpreet Singh","doi":"10.1097/MRR.0000000000000723","DOIUrl":"https://doi.org/10.1097/MRR.0000000000000723","url":null,"abstract":"<p><p>This prospective longitudinal observational study characterized 3-year functional mobility and health-related quality-of-life trajectories following single-event multilevel soft-tissue surgery in 32 children with spastic diplegic cerebral palsy, Gross Motor Function Classification System levels II-IV. Functional Mobility Scale (FMS) scores at 5, 50, and 500 m and parent-proxy Pediatric Quality of Life Inventory (PedsQL) Cerebral Palsy Module scores were assessed preoperatively and at 3, 6, 9 months, 1 year, and 3 years. FMS varied over time at all distances (Friedman P < 0.001). Median 5-m and 50-m FMS fell from 4.5 preoperatively to 2.0 at 3 months and returned to 4.5 by 3 years; baseline-to-3-year shifts were favorable (5 m: Bonferroni-adjusted P = 0.0087, r = 0.608; 50 m: adjusted P = 0.0158, r = 0.579). At 500 m, the median increased from 0 to 4.5 (adjusted P = 0.0191, r = 0.570), while N (does not apply; distance not completed) decreased from 19/32 to 8/32; 4.5 is an interpolated median between categories 4 and 5. Mean PedsQL increased from 68.2 ± 14.7 to 74.3 ± 14.5 (change +6.13, 95% confidence interval = 4.30-7.96; P < 0.001) without early decline. No FMS distance changed significantly from 1 to 3 years. Short- and intermediate-distance mobility showed early deterioration followed by recovery to baseline medians, whereas community mobility and caregiver-reported quality of life showed favorable long-term shifts. These observational changes cannot be attributed solely to surgery.</p>","PeriodicalId":14301,"journal":{"name":"International Journal of Rehabilitation Research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149069475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Household income and postdischarge community activity after stroke: a multicenter prospective cohort study.","authors":"Jeong-Soo Kim, Eu Jeong Ko, In-Geon Hwang","doi":"10.1097/MRR.0000000000000720","DOIUrl":"https://doi.org/10.1097/MRR.0000000000000720","url":null,"abstract":"<p><p>Socioeconomic disadvantage is associated with poorer outcomes after stroke, but its relationship with everyday community activity after discharge is unclear, and income and education may not act alike. We examined associations of household income and spousal cohabitation with postdischarge community activity in a multicenter Korean cohort. At four South Korean rehabilitation centers, 153 community-dwelling stroke survivors completed the Physical Activity Scale for Stroke Patients in Daily Living; 103 with valid monthly household-income data formed the primary sample. Associations with total activity score were examined using Kruskal-Wallis tests and sequential linear regression with heteroscedasticity-consistent robust inference on a common complete-case sample, with center fixed effects, median regression, and adjustment for education as sensitivity analyses. Activity differed across the four income groups (H = 10.233, P = 0.017), concentrated in the highest-income group. Lower income predicted a lower activity score before adjustment (β = -23.62, P = 0.010), after demographic adjustment (β = -17.24, P = 0.041) and with center fixed effects (β = -18.41, P = 0.049), but not after adjustment for walking ability and cognition (β = -12.73, P = 0.139), in median regression (P = 0.243), or after adjustment for education (P = 0.167). Education was not associated with activity in any analysis, and spousal cohabitation showed no association. Household income was related to postdischarge community activity, but the association was statistically fragile and largely explained by functional and cognitive status.</p>","PeriodicalId":14301,"journal":{"name":"International Journal of Rehabilitation Research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149074414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Evan R Zeldin, Gary Allen, Anne Serrao, Harrison Jordan, Kevin Chin, Dmitry Tumin, Clinton Faulk
{"title":"Predicting unplanned acute care transfer from an inpatient rehabilitation facility across rehabilitation populations.","authors":"Evan R Zeldin, Gary Allen, Anne Serrao, Harrison Jordan, Kevin Chin, Dmitry Tumin, Clinton Faulk","doi":"10.1097/MRR.0000000000000722","DOIUrl":"https://doi.org/10.1097/MRR.0000000000000722","url":null,"abstract":"<p><p>Risk factors for acute care transfers (ACTs) from inpatient rehabilitation facilities (IRFs) vary by setting and patient population. Prior risk prediction models designed to apply to all IRF patients in an IRF have achieved poor to acceptable predictive value, while better performance (C-statistic > 0.8) was attained by models isolated to specific impairment groups. Our aim was to determine if a general risk prediction model for ACT attained sufficient predictive utility when applied across all patients requiring IRF stay. We retrospectively reviewed adults admitted to an academic, rural IRF between January 2016 and September 2019. Predictors were selected based on variables that were statistically significant in prior studies, and covariates significant on bivariate analysis were included in a multivariable logistic regression model of ACT. The predictive utility of the model (bootstrapped C-statistic) was evaluated within each impairment group with greater than 100 patients. The analysis included 2275 patients (median age: 64 years; 57% male; 7% with unplanned ACT). Multivariable logistic regression of unplanned ACT demonstrated fair predictive utility [C-statistic: 0.75; 95% confidence interval (CI): 0.72-0.79], while applying the same risk score to individual impairment groups revealed highly heterogeneous C-statistics, from 0.81 (95% CI: 0.72-0.91) among patients with spinal cord dysfunction to 0.63 (95% CI: 0.50-0.75) among patients with amputation. Our derivation of a comprehensive risk score for ACT based on all patients admitted to IRF demonstrated fair predictive utility in the overall cohort, but predictive utility differed strongly across impairment groups. Further work is needed to develop personalized prediction of ACT risk based on the intersection of impairment group, clinical status at IRF admission, and pertinent medical and surgical history.</p>","PeriodicalId":14301,"journal":{"name":"International Journal of Rehabilitation Research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149016439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Discriminative accuracy of the 42-point modified Mini-Balance Evaluation Systems Test for identifying Expanded Disability Status Scale-defined disability in relapsing-remitting multiple sclerosis: an exploratory diagnostic accuracy study.","authors":"Tadeja Hernja Rumpf","doi":"10.1097/MRR.0000000000000721","DOIUrl":"https://doi.org/10.1097/MRR.0000000000000721","url":null,"abstract":"<p><p>Balance impairment is common in multiple sclerosis, but the discriminative performance of clinical balance measures for Expanded Disability Status Scale (EDSS)-defined disability remains unclear. I compared the 42-point modified Mini-Balance Evaluation Systems Test (modified Mini-BESTest) and the Single-Leg Stance Test (SLST) for EDSS greater than or equal to 4.0 in adults with relapsing-remitting multiple sclerosis. This secondary, single-center, cross-sectional diagnostic accuracy analysis used prospectively collected data from 54 ambulatory participants with static or dynamic balance impairment (EDSS = 1.0-6.0). Both balance tests were administered during the same outpatient visit, while EDSS was assessed separately by a neurologist. Areas under the receiver operating characteristic curve (AUC) were compared using the DeLong test; associations were estimated with Firth penalized logistic regression, and the Youden-derived threshold was assessed by bootstrapping. Twenty-five participants (46%) had EDSS greater than or equal to 4.0. The modified Mini-BESTest showed an AUC of 0.95 [95% confidence interval (CI) = 0.90-1.00], exceeding the SLST (0.77, 0.65-0.90; DeLong Z = 3.18, P = 0.002). An exploratory threshold of less than or equal to 31/42 yielded 92% sensitivity, 90% specificity, a positive likelihood ratio of 8.9 and a negative likelihood ratio of 0.09, and recurred in 79% of 2000 bootstrap resamples. Each additional point was associated with lower adjusted odds of EDSS greater than or equal to 4.0 (odds ratio = 0.75, 95% CI = 0.61-0.86). The modified Mini-BESTest showed excellent discrimination and outperformed the SLST. The less than or equal to 31/42 threshold is exploratory, requires external validation, and must not be applied to the standard 28-point Mini-BESTest.</p>","PeriodicalId":14301,"journal":{"name":"International Journal of Rehabilitation Research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149016446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samantha J Stauffer, Ryan T Pohlig, John R Horne, Frank B Sarlo, Jaclyn M Sions
{"title":"Multisite pain is related to performance-based function after lower-limb loss: a secondary analysis of cross-sectional data.","authors":"Samantha J Stauffer, Ryan T Pohlig, John R Horne, Frank B Sarlo, Jaclyn M Sions","doi":"10.1097/MRR.0000000000000718","DOIUrl":"https://doi.org/10.1097/MRR.0000000000000718","url":null,"abstract":"<p><p>Following lower-limb loss (LLL), more than 50% of adults report multisite pain, that is, pain in two or more distinct sites, which is associated with self-reported activity restriction and higher fall risk. This study examined relationships between multisite pain and performance-based mobility among adults with LLL. During an outpatient Limb Loss Clinic, participants completed the timed up and go, the 10-m walk test, and the 6-min walk test. Linear regression modeling (P ≤ 0.0125) evaluated relationships between multisite pain and performance-based measures, considering covariates (e.g. age, sex, amputation level, and time since amputation). Of 112 adults greater than or equal to 6 months after LLL (55.2 ± 13.8 years; 77.7% male), 55.4% had multisite pain. Individuals with multisite pain had slower self-selected (b = -0.126, P = 0.010) and fast (b = -0.172, P = 0.012) gait speeds and shorter 6-min walk test distances (b = -60.87, P = 0.010). Beyond covariates, multisite pain explained 4.2-5.0% of the variance in performance-based measures. Multisite pain should be considered when evaluating performance-based mobility following LLL.</p>","PeriodicalId":14301,"journal":{"name":"International Journal of Rehabilitation Research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148906291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The bone turnover marker procollagen type I N-terminal propeptide is associated with 12-week neurogenic heterotopic ossification after traumatic brain injury.","authors":"Seongmin Choi, Eo Jin Park","doi":"10.1097/MRR.0000000000000719","DOIUrl":"https://doi.org/10.1097/MRR.0000000000000719","url":null,"abstract":"<p><p>Neurogenic heterotopic ossification (NHO) after traumatic brain injury may involve osteogenic synthesis of a type I collagen-rich matrix. Procollagen type I N-terminal propeptide (P1NP) reflects type I collagen formation. This single-center retrospective cohort study examined whether baseline P1NP was associated with radiographic NHO within 12 weeks after traumatic brain injury. We reviewed 124 adults transferred to physical and rehabilitation medicine within 21 days after injury who completed 26-34 days of inpatient rehabilitation and had 12-week follow-up. The primary Firth penalized logistic regression model included P1NP per 50 ng/ml, acute care length of stay per 5 days, overall Modified Ashworth Scale score per 5 points, and neutrophil-to-lymphocyte ratio. Twelve-week NHO occurred in 19 (15.3%) patients. Higher P1NP was associated with NHO in the primary model (odds ratio: 6.11, 95% confidence interval: 1.34-33.97; P = 0.013). Longer acute care length of stay, higher overall Modified Ashworth Scale score, and higher neutrophil-to-lymphocyte ratio were also associated with NHO. In a supplementary model replacing acute care length of stay with the Disability Rating Scale, P1NP did not reach statistical significance (odds ratio: 4.63, 95% confidence interval: 0.85-30.18; P = 0.062). In adults with traumatic brain injury undergoing early inpatient rehabilitation, higher baseline P1NP was associated with 12-week NHO in the primary model. Prospective studies with standardized imaging and serial sampling are needed to confirm its predictive value.</p>","PeriodicalId":14301,"journal":{"name":"International Journal of Rehabilitation Research","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148887554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aryane Caroline Silva, Ludmilla Ribeiro Batista, Carolina Luísa de Almeida Soares, Iza Faria-Fortini, Kênia Kiefer Parreiras de Menezes, Christina Danielli Coelho de Morais Faria
{"title":"Upper limb function predicts quality of life at three and six months after hospital discharge in individuals with stroke: a prospective longitudinal study.","authors":"Aryane Caroline Silva, Ludmilla Ribeiro Batista, Carolina Luísa de Almeida Soares, Iza Faria-Fortini, Kênia Kiefer Parreiras de Menezes, Christina Danielli Coelho de Morais Faria","doi":"10.1097/MRR.0000000000000712","DOIUrl":"10.1097/MRR.0000000000000712","url":null,"abstract":"<p><p>This study aimed to determine whether the upper limb function assessed after stroke during hospital admission predicts health-related quality of life (HRQoL) in individuals with stroke after 3 and 6 months of discharge. This is a prospective longitudinal study. The possible predictors were handgrip strength of the paretic side, upper limb motor recovery (Fugl-Meyer Assessment), upper limb performance in self-care activities (items of eating, personal hygiene, and dressing scores of the modified Barthel Index), and functional independence (modified Barthel Index total score), assessed at hospital discharge. HRQoL was assessed using generic (36-Item Short Form Health Survey) and specific (Stroke Specific Quality of Life) questionnaires at 3 and 6 months after stroke. At 3 months after stroke, upper limb performance in personal hygiene and handgrip strength of the paretic side predicted generic (27%; F = 6.85, P = 0.005) and specific (38%; F = 6.35, P = 0.003) HRQoL. At 6 months after stroke, handgrip strength of the paretic side was the only significant predictor of generic HRQoL (15%; F = 12.90, P < 0.001), and upper limb performance in personal hygiene and upper limb motor recovery were the only significant predictors of specific HRQoL (30%; F = 7.69, P = 0.008). Upper limb performance in personal hygiene and handgrip strength of the paretic side assessed immediately after stroke predicted generic and specific HRQoL at 3 months after stroke. These variables were also important at 6 months, with handgrip strength of the paretic side being the single predictor for generic HRQoL, and upper limb performance in personal hygiene, together with upper limb motor recovery, being the predictors for specific HRQoL.</p>","PeriodicalId":14301,"journal":{"name":"International Journal of Rehabilitation Research","volume":" ","pages":"191-196"},"PeriodicalIF":1.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148198804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Site-specific effects of transcranial direct current stimulation on motor function in Parkinson's disease: a systematic review and meta-analysis.","authors":"Julie Tachet, Maxime Bouriaud, Gauthier Everard","doi":"10.1097/MRR.0000000000000709","DOIUrl":"10.1097/MRR.0000000000000709","url":null,"abstract":"<p><p>We aimed to compare the effect of transcranial direct current stimulation (tDCS) compared with sham or conventional interventions on motor functions and activity in individuals with Parkinson's disease. Two independent reviewers searched four databases (PubMed, Embase, Scopus, and Cochrane Library) from inception to April 2026. We only included randomized controlled trials comparing active tDCS (alone or with training) versus sham tDCS (alone or with training) on walking speed, functional mobility, Parkinson motor symptoms, activities of daily living, quality of life (QoL), dropouts, and adverse events. Two authors independently extracted data, including study source and design, participant and intervention characteristics, and outcomes. We computed a mean difference with a random-effects model. Subgroup analyses were performed for outcomes with greater than or equal to 10 experimental study arms, accounting for intervention protocol and stimulation site. We assessed the risk of bias using ROB 2 tool, and the certainty of evidence using Grading of Recommendations Assessment, Development, and Evaluation. Seventeen randomized controlled trials ( n = 553) were included. Pooled analyses showed little to no effect on walking speed (mean difference: 0.04 m/s 2 , 95% confidence interval: -0.03 to 0.11), functional mobility (mean difference: 0.67 s gained on the Timed Up and Go test, 95% confidence interval: -0.64 to 2.02), and other outcomes. Subgroup analyses based on stimulation site and intervention protocol revealed no differences. Adverse events were minor and infrequent, and dropout rates did not differ between groups. The overall certainty of evidence ranged from very low to low. Current evidence suggests that the effect of tDCS on gait, activities of daily living, or quality of life is probably not superior to other conventional interventions in individuals with Parkinson's disease.</p>","PeriodicalId":14301,"journal":{"name":"International Journal of Rehabilitation Research","volume":" ","pages":"169-190"},"PeriodicalIF":1.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148015570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mikhail Saltychev, Konsta Koivunen, Katri Pernaa, Juhani Juhola
{"title":"Identifying classes with different disability profiles among patients undergoing lumbar discectomy: a latent class analysis.","authors":"Mikhail Saltychev, Konsta Koivunen, Katri Pernaa, Juhani Juhola","doi":"10.1097/MRR.0000000000000707","DOIUrl":"10.1097/MRR.0000000000000707","url":null,"abstract":"<p><p>The objective of this retrospective register-based study among 534 patients undergoing lumbar discectomy was to identify larger classes with different functional profiles. Main statistical method was latent class analysis. The mean age was 46.0 (17.8) years. Based on the distribution of 10 domains of functioning included in Oswestry Disability Index, four latent classes were identified: 'no or mild disability' (26% of the sample); 'moderate restrictions in sitting and traveling' (26%); 'moderate restrictions in standing and lifting and severe pain' (19%); and 'severe disability in most of the domains' (30%). Female sex (49 vs. 37%), obesity (48 vs. 28%), older age (63 vs.42%), greater pain severity (73-83 vs. 59-65%), and longer preoperative pain (27 vs. 20%) were associated with a higher likelihood of classification into a severe disability class. The results show that the functional difficulties of patients undergoing lumbar discectomy are not evenly distributed in the same way across individuals and are not simply a matter of variation at the individual level. It seems that there are larger classes whose disability domains are distributed in a different way than other classes. Belonging to a particular class can potentially be predicted by descriptive factors such as sex, age, pain intensity and pain history. This information can help identify risks that predict particularly severe disability and recognize the most common functional limitations that may be overlooked if all the patients are treated as a homogeneous group and the severity of disability is described by only one composite score .</p>","PeriodicalId":14301,"journal":{"name":"International Journal of Rehabilitation Research","volume":" ","pages":"214-221"},"PeriodicalIF":1.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147868277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seung Heun An, Eun Joo Kim, Sung Phil Yang, Jun Min Lee
{"title":"Comparison of the 2-min walk test and the first 2-min performance of the 6-min walk test across walking conditions in subacute stroke.","authors":"Seung Heun An, Eun Joo Kim, Sung Phil Yang, Jun Min Lee","doi":"10.1097/MRR.0000000000000710","DOIUrl":"10.1097/MRR.0000000000000710","url":null,"abstract":"<p><p>Walking endurance is commonly assessed using the 6-min walk test (6MWT), but its duration may limit repeated assessments in the subacute phase, and shorter alternatives [2-min walk test (2MWT) and first 2-min performance of the 6MWT (2'6MWT)] remain insufficiently characterized across different walking environments. This retrospective observational study examined the measurement properties of 2MWT and 2'6MWT in 20 individuals with subacute stroke under two indoor walking path configurations: a rectangular path (11.5 × 5 m) requiring repeated turns and a 30-m straight path. Test-retest reliability, measurement error, convergent validity, and explanatory capacity were evaluated. Both indices showed excellent test-retest reliability (intraclass correlation coefficient = 0.973-0.988). Measurement error was higher on the rectangular path than on the straight path (minimal detectable change: 22.0-24.3 vs. 15.8-18.9 m). Correlations with the 6MWT were strong ( r = 0.936-0.988). The 2MWT distance explained 94 and 95% of the variance in 6MWT distance on the rectangular and straight paths, whereas the 2'6MWT distance explained 77 and 96%. Adding the Berg Balance Scale and Fugl-Meyer Assessment for the lower extremity substantially improved the 2'6MWT model on rectangular path (Δ R2 = 0.15), with minimal changes elsewhere (Δ R2 = 0.008-0.011). These findings suggest that both the 2MWT and 2'6MWT may serve as reliable and valid measures of walking endurance. However, the strength of association varied by walking path configuration, with reduced explanatory power for the 2'6MWT on the rectangular path, suggesting environment-specific influences on performance. Accordingly, interpretation of these endurance tests should account for walking path configuration and dimensions, which should be routinely reported.</p>","PeriodicalId":14301,"journal":{"name":"International Journal of Rehabilitation Research","volume":" ","pages":"206-213"},"PeriodicalIF":1.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148030513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}