2011 International Workshop on Biophotonics最新文献

{"title":"Bone tissue ablation by femtosecond laser beam","authors":"I. Ioniță, M. Zamfirescu","doi":"10.1109/IWBP.2011.5954802","DOIUrl":"https://doi.org/10.1109/IWBP.2011.5954802","url":null,"abstract":"We report here bone tissue ablation experiments performed with femtosecond laser. We determined ablation threshold value of human mandible which is the hardest bone of the skull.","PeriodicalId":142421,"journal":{"name":"2011 International Workshop on Biophotonics","volume":"62 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114016911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glass-clad crystal fibers based functional optical coherence tomography","authors":"T. Ho, N. Cheng, C. K. Chang, K. Hsu, D. Jheng, Y. T. Wang, Y. S. Lin, C. Lai, P. Huang, S. L. Huang, P. S. Yeh, J. Tjiu","doi":"10.1109/IWBP.2011.5954852","DOIUrl":"https://doi.org/10.1109/IWBP.2011.5954852","url":null,"abstract":"Broadband emissions centered at 560 nm, 770 nm, and 1380 nm from glass-clad crystal fibers with 3-dB bandwidths of 98, 180, and 240 nm were used for various biomedical and in-vivo optical tomography applications with cellular resolution. The adjacent image pixel cross talks are less than −20 dB due to the near Gaussian spectral shapes of the broadband emissions.","PeriodicalId":142421,"journal":{"name":"2011 International Workshop on Biophotonics","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124873090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single particle tracking of amyloid oligomers on the plasma membrane of living cells","authors":"Martino Calamai, F. Pavone","doi":"10.1109/IWBP.2011.5954833","DOIUrl":"https://doi.org/10.1109/IWBP.2011.5954833","url":null,"abstract":"This research uses innovative nanotechnology approaches to tackle the causes of Alzheimer's disease and other amyloid disorders. The ultimate goal is the development of alternative strategies to study these debilitating pathologies.","PeriodicalId":142421,"journal":{"name":"2011 International Workshop on Biophotonics","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128889468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of scanning ion conductance microscopy to map elastic properties of cell membranes","authors":"M. Pellegrino, P. Orsini, M. Pellegrini, E. Tognoni, P. Baschieri, F. Dinelli, D. Petracchi, C. Ascoli","doi":"10.1109/IWBP.2011.5954800","DOIUrl":"https://doi.org/10.1109/IWBP.2011.5954800","url":null,"abstract":"We discuss on the feasibility of mapping the elastic properties of cellular regions with small thickness by means of a Scanning Ion Conductance Microscope employed to deliver mechanical stimuli in noncontact mode.","PeriodicalId":142421,"journal":{"name":"2011 International Workshop on Biophotonics","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125356714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experimental study on laser assisted vascular repair and anastomosis with ICG-infused chitosan films","authors":"F. Rossi, P. Matteini, F. Ratto, R. Pini, G. Esposito, A. Albanese, A. Puca, G. Maira, Giovanni Battista Rossi","doi":"10.1109/IWBP.2011.5954804","DOIUrl":"https://doi.org/10.1109/IWBP.2011.5954804","url":null,"abstract":"Laser-based approach for suturing biological tissues is emerging as a valid alternative to conventional techniques, because of its widely demonstrated advantages, such as immediate watertight closure of the wound, minimal inflammatory response and scar formation, and reduced wound healing time. Moreover the laser based techniques may provide suturing in hardly accessible sites (e.g. in microsurgery, endoscopic and minimally invasive surgery) or in thin tissues that are impossible to treat with staples and/or stitches (e.g. the lens capsule bag). Usually, the biological tissue is stained with a liquid or semisolid preparation of organic chromophores (indocyanine green - ICG): a near infrared laser light is locally absorbed and converted into a photothermal effect, thus inducing welding of the wound. Some limitations are ascribed to the use of organic chromophores, such as their poor photochemical stability, excessive diffusiveness in the biological matrices and inadequate stability when stored in an aqueous solution or dispersed in a physiological environment. To overcome these problems we proposed the use of chitosan matrices, properly stained with conventional chromophores (ICG). The Indocyanine Green (ICG) is included into the chitosan matrices: the matrix enwraps the chromophore particles, thus enhancing their stability, durability and effectiveness. The final product has thus the necessary optical and mechanical characteristics to design a safe and standard laser-based tissue closuring procedure. The ICG infused chitosan patches were used to perform Laser Assisted Vasular Repair (LAVR) and Anastomosis (LAVA) in an in vivo experimental study in carotid rabbits. An ICG-infused chitosan patch was used to wrap the artery in the lesion area. A diode laser emitting at 810 nm, equipped with a 300 °m diameter optical fiber was used to weld the patch onto the artery wall, by delivering single laser spots to induce local patch/tissue adhesion. The result is an immediate closure of the wound, with no bleeding at clamps release. The animals were observed during follow-up. All the anastomosis were patent, no bleeding signs were documented. The carotid samples underwent histological examinations. The advantages of the proposed technique are: simplification of the surgical procedure and shortening of the operative time; decreased foreign-body reaction; reduced inflammatory response and improved vascular healing process.","PeriodicalId":142421,"journal":{"name":"2011 International Workshop on Biophotonics","volume":"03 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127452216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-contact monitoring of heart beat using optical laser diode vibrocardiography","authors":"G. Capelli, C. Bollati, G. Giuliani","doi":"10.1109/IWBP.2011.5954805","DOIUrl":"https://doi.org/10.1109/IWBP.2011.5954805","url":null,"abstract":"In the present work we use a compact and low-cost laser sensor based on self-mixing effect for non-invasive non-contact analysis of heart beat, by measuring the vibrations of the skin surface caused by vascular wall motion in carotid, radial and dorsal pedal arteries. The electrocardiography (ECG) and optical vibrocardiography (VCG) signals are simultaneously acquired and analyzed. VCG can be exploited for testing medical parameters beyond the heart rate, such as artery deformation, vessel elasticity and blood pulse characteristics.","PeriodicalId":142421,"journal":{"name":"2011 International Workshop on Biophotonics","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127886065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of water absorption on the stability of a polymer based Young's interferometric sensor","authors":"Meng Wang, R. Myllyla, J. Hiltunen, S. Uusitalo, L. Hakalahti","doi":"10.1109/IWBP.2011.5954831","DOIUrl":"https://doi.org/10.1109/IWBP.2011.5954831","url":null,"abstract":"In this work the refractive index change of a polymer (Ormocer) based waveguide interferometer under the influence of water absorption was analyzed. The water absorption caused refractive index change was up to 10−4. After half an hour contacting with deionized water a pseudo-equilibrium state was reached and the response of the sensor tended to be stabilized. We performed refractive index measurement with glucose water dilutions. The measured refractive index change showed a linear relationship with the glucose concentration.","PeriodicalId":142421,"journal":{"name":"2011 International Workshop on Biophotonics","volume":"238 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114638207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long period optical fiber grating outcladding overlaid sensors: A versatile photonic platform for health and bio applications","authors":"S. Pissadakis, D. Anglos, A. Klini, M. Konstantaki","doi":"10.1109/IWBP.2011.5954850","DOIUrl":"https://doi.org/10.1109/IWBP.2011.5954850","url":null,"abstract":"Long period fiber gratings with suitable thin film overlayers can constitute a strong platform for the development of versatile and multi-functional sensing devices for serving diverse Biological and Health monitoring applications. Herein, we present three cases of thin film overlaid long period gratings that can find direct application in health related applications: the first example refers to a humidity sensing device utilizing PEO/CoCl2 overlayers, and, the second refers to a simple radiation dose sensor utilizing spiropyran doped PMMA overlayers. In the final case, a vapor detection probe is demonstrated utilizing a zinc oxide (ZnO) nanorods coating. The proof of principle of these devices is presented, in conjunction with experimental results on their performance, while their application in health related applications is projected and discussed.","PeriodicalId":142421,"journal":{"name":"2011 International Workshop on Biophotonics","volume":"126 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127400440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of biopsy samples with optical computed tomography","authors":"G. Zacharakis, G. Spiliopoulos, R. Favicchio, J. Ripoll, Athanasios Kokolakis, K. Lasithiotakis, K. Krasagakis, E. Giannikaki, Androniki Toska","doi":"10.1109/IWBP.2011.5954796","DOIUrl":"https://doi.org/10.1109/IWBP.2011.5954796","url":null,"abstract":"Multimodal photonic imaging has been applied for the accurate investigation of biological specimens ranging from biopsy samples to small animals, providing direct imaging of physiology and pathology during disease progression, e.g. cancer proliferation","PeriodicalId":142421,"journal":{"name":"2011 International Workshop on Biophotonics","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125014558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of protein aggregation with a Bloch Surface Wave sensor","authors":"V. Paeder, S. Santi, L. Hvozdara, V. Musi, H. Herzig","doi":"10.1109/IWBP.2011.5954811","DOIUrl":"https://doi.org/10.1109/IWBP.2011.5954811","url":null,"abstract":"We present a study of the dynamics of protein aggregation using a common path heterodyne Bloch surface wave label-free sensing scheme. We demonstrate the ability to detect, during thermal incubation, the first early dynamics events of protein aggregation and fibrillogenesis of amyloid-beta peptides, linked to Alzheimer's Disease. The calibration of the biosensor is made using Lysozyme protein, a well establish protein model system to examine structural and mechanistic principles. The sensor is able to detect the formation of small soluble aggregates at early stages of oligomerisation.","PeriodicalId":142421,"journal":{"name":"2011 International Workshop on Biophotonics","volume":"86 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123175186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}