International journal of reproduction, contraception, obstetrics and gynecology最新文献

{"title":"Study of fetomaternal implications in intrauterine growth restriction pregnancies","authors":"Prachi Sharma, Amiya U. Mehta","doi":"10.18203/2320-1770.ijrcog20240783","DOIUrl":"https://doi.org/10.18203/2320-1770.ijrcog20240783","url":null,"abstract":"Background: Fetal growth restriction (FGR) is a pathological condition in which a fetus has not achieved its genetic growth potential. FGR incidence is 6 times higher in underdeveloped and developing countries as compared to the developed world.\u0000Methods: This is a retrospective study done in the department of obstetrics and gynaecology, civil hospital and B. J. Medical college, Ahmedabad over the period of 6 months from December 2022 to May 2023. A total of 30 cases of intrauterine growth restriction (IUGR) pregnancies were studied.\u0000Results: Majority of the study population, 60% belonged to younger age group of 20-30 years. Multiparity was associated with IUGR babies. Majority of patients i.e. 76.66%. Presented at gestational age of ≥37 weeks and 23.33% at <37 weeks. Most IUGR babies (73.33%) had a birth weight between 2 to 2.5 kg. One third of babies required NICU admission while the perinatal mortality was 10%. Doppler changes in umbilical artery were noted in 27% of cases of IUGR. Among risk factors anemia, preeclampsia and oligohydramnios had equal contributions at 10% each. Previous history for SGA baby is a significant association in 16% of cases. Induction of labor was done in 60% cases, 63% were delivered vaginally and rest via lower segment caesarean section (LSCS), the most common indication of LSCS was fetal distress.\u0000Conclusions: The study concluded that IUGR continues to be one of the major etiological factors for fetal morbidity and mortality and increase in rates of LSCS contributing maternal morbidity. IUGR was commonly observed in multigravida patients lacking antenatal care. Anemia and hypertensive disorders of pregnancy as well as oligohydramnios are the potential risk factors for IUGR.","PeriodicalId":14225,"journal":{"name":"International journal of reproduction, contraception, obstetrics and gynecology","volume":"130 28","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140369903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human papillomavirus genotype distribution among colposcopy diagnosed cervical precancerous lesions","authors":"Fahmida Sultana, Mishkat Tabassum, M. Jakanta Faika, Anamica Dev, K. S. Haque, M. N. Aktar, S. N. Sharmin, A. Nessa","doi":"10.18203/2320-1770.ijrcog20240767","DOIUrl":"https://doi.org/10.18203/2320-1770.ijrcog20240767","url":null,"abstract":"Background: Cervical cancer (CC) is one of the primary causes of gynaecological cancer death. Cervical cancer is the fourth most frequent cancer worldwide, and it is the second most common cancer in Bangladesh. The stage of cervical cancer at diagnosis has a significant impact on survival. Cervical cancer mortality is high in Bangladesh due to late detection and limited management facilities. The aim of the study was to determine the pattern of human papillomavirus (HPV) genotype among colposcopy diagnosed cervical precancerous lesions.\u0000Methods: This cross-sectional study was conducted in the department of gynecological oncology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka. Total of 142 women attending the colposcopy clinic of BSMMU.\u0000Results: The mean age was found 38.7±7.3 years with a range from 30 to 60 years. 10 (7.0%) patients were found HPV 16 positive followed by 1 (0.7%) HPV 18, another hr-HPV 3 (2.1%), HPV 16 and other hr-HPV 3 (2.1%) and HPV 16, HPV 18 and other hr-HPV 1 (0.7%). Regarding colposcopy reports 99 (69.7%) patients had CIN I, 33 (23.7%) had CIN II and 10 (7.0%) had CIN III identification by colposcopy reports. 61 (43.0%) patients had CIN I followed by 15 (10.6%) had CIN II, 11 (7.7%) had CIN III, 7 (4.9%) had CIS, and 48 (33.8%) had normal or squamous metaplasia by histopathological reports.\u0000Conclusions: It can be concluded that among all the 14 hr-HPV genotype HPV 16 is more prevalent while HPV18 prevalence was very low in colposcopy diagnosed cervical precancer cases. The study revealed HPV16 was more common among high grade lesions.","PeriodicalId":14225,"journal":{"name":"International journal of reproduction, contraception, obstetrics and gynecology","volume":"108 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140370434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of abruptio placenta in patient with pre-eclampsia with severe features and without severe features","authors":"Rakshith Nagaraj, Hemalatha C. Ramakrishnappa, Anusha B. Chandrashekhar, Swathi L. Iyengar","doi":"10.18203/2320-1770.ijrcog20240786","DOIUrl":"https://doi.org/10.18203/2320-1770.ijrcog20240786","url":null,"abstract":"Background: Placental abruption is responsible for increased risk of maternal and fetal morbidity and mortality worldwide. Studies specific to placental abruption in pregnancy-induced hypertension (PIH) are still lacking. This study is designed to focus on collecting data on placental abruption and to objectively determine its impact on the outcome of pregnancy complicated with PIH in terms of improving fetal and maternal morbidity and mortality.\u0000Methods: This was retrospective observational study conducted at Cheluvamba Hospital, Mysore Medical College and Research Institute (MMCRI), Mysore, in the department of obstetrics and gynaecology. All pregnant women with diagnosis of abruptio placenta over 28 weeks and with PIH between January 2022 to August 2023 were included. Data was collected from medical records department and results were analysed.\u0000Results: During the study period there were total of 14027 deliveries. Of this 63 (0.44%) occurred in patients with placental abruption with PIH. Mean age group was 24.57 years; majority were multigravida (58.46%) Majority were preterm (77.77%). 61.90% had pre-eclampsia with severe features. Mean systolic blood pressure (SBP) was 151.90 mmHg, diastolic blood pressure (DBP) was 98.73 mmHg. 65.08% delivered by caesarean section. 47.61% was the perinatal mortality, perinatal asphyxia was 45.71%, prematurity was 65.71%, low birth weight was 84.12%. 71.42% was the neonatal intensive care unit (NICU) admission rate. Maternal complications seen was postpartum haemorrhage (PPH) (31.74%), requiring blood and blood products transfusion (63.49%), coagulopathy (14.28%), shock (12.69%). 4 women developed severe features of pre-eclampsia in postpartum period, 2 of them needed MgSO4. 58.73% had requirement of antihypertensives in postpartum period.\u0000Conclusions: Abruption is one of the obstetric emergencies. In our study severe adverse maternal and perinatal outcomes were more pronounced in pre-eclampsia with severe features and it needs an individual and intense surveillance and management to have better maternal and perinatal outcome.","PeriodicalId":14225,"journal":{"name":"International journal of reproduction, contraception, obstetrics and gynecology","volume":"51 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140371423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative study between vaginal sacrospinous ligament fixation with abdominal sacrocolpopexy","authors":"Renu Chaudhary, Shakun Singh, Anupam Rani, R. Chaudhary","doi":"10.18203/2320-1770.ijrcog20240808","DOIUrl":"https://doi.org/10.18203/2320-1770.ijrcog20240808","url":null,"abstract":"Vaginal vault prolapse is about 4-6 per 1000 but it is increasing with increase in life expectancy with more number of years in menopausal age. It is not a common condition following abdominal and vaginal hysterectomy. It has a negative impact on the quality of life of women due to incontinence of urine, irregular defecation symptoms and sexual dysfunction along with psychosocial problems. This study compares the efficacy of most two successful surgeries which were done by abdominal and vaginal route for correcting post hysterectomy vault prolapse by postoperative assessment and at least 6 to 12 months follow up. This is the retrospective case series among post hysterectomy women attending the Gynae OPD in SVBP hospital associated with LLRM medical college Meerut from January 2022 to January 2023. Study population included 19 women divided into two groups; group 1 includes 8 women who underwent unilateral sacrospinous ligament fixation and group 2 includes 11 women who underwent abdominal sacrocolpopexy. In demographic and clinical features between the two groups, there is no statistically difference found in terms of mean age, mean weight, mean BMI and mean parity. Hence, both groups are comparable. The operating time is longer in ASC (85.90±40.23 minutes) group when compared to SSF group (43.43±6.9 minutes) (p value= 0.00096), blood loss reported in ASC (341.72±37.14 ml) slightly more than in SSF group (237.5±32.84 ml) (p value= 0.0001) and mean hospital stay is longer in ASC (6±5.1 days) than SSF group (3.2±0.9 days) (p value=0.0001). Other complications like postoperative pyrexia, wound infection, urinary complaints were higher in ASC group and at follow up, the mean vaginal length was longer in ASC (6.9±0.8 cm) then SSF (5.2±0.8cm) group (p value=0.0005). We concluded that as the ultimate aim of vault prolapse surgery is to improve the function and restoring anatomy and to improve the quality of life, in that respect, both abdominal sacrocolpopexy and sacrospinous ligament fixation both are effective methods and less complications are noted in SSF group. It also depends on the hands of an expert, though recovery time is faster in SSF than ASC group.","PeriodicalId":14225,"journal":{"name":"International journal of reproduction, contraception, obstetrics and gynecology","volume":"26 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140372724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A cross-sectional study to evaluate uploader-based quality and reliability of content on YouTube about endometriosis","authors":"Shereece Clarke, Monica Ghotra, Mahima Kuruvila, Aarushi Venkatraman, Vasishtha A. Upadrasta, Khrystyna Melnyk","doi":"10.18203/2320-1770.ijrcog20240776","DOIUrl":"https://doi.org/10.18203/2320-1770.ijrcog20240776","url":null,"abstract":"Background: Endometriosis is characterized by the development and presence of endometrial glands and stroma outside of the uterine cavity. Reflux of endometrial tissue fragments, cells, and protein-rich fluid into the pelvis during menstruation is considered the most important mechanism for the development of endometriosis, which is termed reflux menstruation. This study aims to assess quality and reliability of information on YouTube related to endometriosis.\u0000Methods: A cross-sectional observational study of YouTube videos was conducted in April 2023. Videos related to endometriosis were searched by six authors, easy using one search term. Relevant videos in English or Hindi language of duration 1-20 minutes were included in the study. These were evaluated for type of uploader, popularity, type of content and lastly quality and reliability using global quality score (GQS) and DISCERN scores respectively.\u0000Results: The 67 relevant videos conveying Endometriosis related information had 21,620,808 views, 120,830 likes and 11,655 comments. Around 31 (46.3%) of videos uploaded were by doctors and health care organizations, outnumbering those uploaded by news channels 14 (20.9%), patients 5 (7.5%), and others 17 (25.4%). 59 (88.06%) of these videos described symptoms of endometriosis, and 67.1% presented the cause or etiology. A total of 47 (70.1%) of videos discussed information regarding treatment options.\u0000Conclusions: YouTube videos have a wide reach among audience. In this study it was found that there was no significant difference in the quality, reliability or video power index (VPI) of videos uploaded by different types of uploaders. It is important to ensure that content with high quality and reliability is available from qualified medical professionals and organizations; for viewers to understand their disease and take treatment decisions.","PeriodicalId":14225,"journal":{"name":"International journal of reproduction, contraception, obstetrics and gynecology","volume":"25 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140372731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pre-conception and pre-natal diagnostic techniques act-draconian or a considerate de jure tamer","authors":"Vasudha Khanna, K. M. Gopal","doi":"10.18203/2320-1770.ijrcog20240822","DOIUrl":"https://doi.org/10.18203/2320-1770.ijrcog20240822","url":null,"abstract":"Principles of gender equity are an integral part of constitution. The constitution confers equal rights and opportunities on women; bars discrimination on the basis of sex and denounces practices derogatory to the dignity of women. In spite of this, discrimination against women and girls is almost universal. Forced abortions of female foetuses and prenatal sex determination results in millions of girls not being allowed to be born just because they are girls. Pre-conception and pre-natal diagnostic techniques (PC and PNDT) act were enacted in 1994, amended and effectively implemented in 2003 and strictly amended in 2011, to curb this heinous crime of female foeticide that was taking place due to prenatal diagnostic techniques for determination of the sex of the foetus and thus, to balance the disturbed sex ratio of the country. To achieve the said purposes, the act imposes penalties for the offences committed under this Act, including clerical errors. However, according to the radiologists, the PC and PNDT act has become draconian for all practicing sonologists and radiologists instead of serving the purpose of saving the girl child. This article, explaining the provisions of PC and PNDT act, addresses the concerns of sonologists and radiologists in the light of the judgements passed by Hon’ble Supreme Court of India. It further discusses the hindrances occurring in the usage of evolved medical technology due to the provisions of the Act thereby paving way towards a much-needed legitimate decision to settle the ongoing country-wide debate.","PeriodicalId":14225,"journal":{"name":"International journal of reproduction, contraception, obstetrics and gynecology","volume":"132 36","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140369864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Female pelvic floor myofascial syndrome and its relationship with lower urinary tract storage symptoms","authors":"José I. Leyva Vázquez, Guadalupe Guerrero Reyes, Adrián Gutiérrez González, Ricardo Hernández Velázquez, Karen M. Loya Maldonado, Omar Treviño Cavazos, Jennifer E. Reyes Alcaraz, Alejandra Robledo Torres, Sara Y. Saca Cuevas, Juan C. Herrera Morales","doi":"10.18203/2320-1770.ijrcog20240772","DOIUrl":"https://doi.org/10.18203/2320-1770.ijrcog20240772","url":null,"abstract":"Background: Pelvic floor myofascial syndrome is defined as non-articular skeletal muscle pain, characterized by the presence of trigger points. Present in 14-23% of patients with chronic pelvic pain. It has an impact on urinary function. The prevalence of lower urinary tract symptoms is 15-67%, with storage symptoms predominating in patients with PFMS. Objective was to determine the relationship between female pelvic floor myofascial syndrome and lower urinary tract storage symptoms.\u0000Methods: This was a retrospective, observational, descriptive, cross-sectional, homodemic and single-center study at University Hospital Doctor José Eleuterio González, Monterrey, Nuevo Leon, Mexico from period one from April 1st to June 30th, 2022. Type of non-probabilistic convenience sampling. Database in Excel 2016, Pearson's Х² statistical test in the SPSS V25® program.\u0000Results: 136 patients with PFMS and LUTS storage were evaluated. The most frequent age group was 46-55 years with 33.1% (N=45); the marital status was married with 74.3% (N=101). In relation to education 55.9% (N=76) with a bachelor's degree. The most frequent storage symptoms were nocturia 67.6% (N=92) p<0.05, frequency 60.3% (N=82) p=0.512, urgency 57.4% p<0.005.\u0000Conclusions: Knowing the correlation between PFMS and storage LUTS can guide specific pain treatment with review of urinary symptoms. In patients with nocturia, frequency, urgency, SUI and UUI, a physical examination should be performed and included trigger points in the pelvic floor. Nocturia is the most prevalent storage LUTS in PFMS.","PeriodicalId":14225,"journal":{"name":"International journal of reproduction, contraception, obstetrics and gynecology","volume":"35 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140372307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison between colposcopic and biopsy findings to determine the frequency cervical intraepithelial neoplasia I to III in visual inspection with acetic acid","authors":"Khaleda Akter Bhuiyan, Deepa Das, Mumu Tasnuva Sharmin","doi":"10.18203/2320-1770.ijrcog20240775","DOIUrl":"https://doi.org/10.18203/2320-1770.ijrcog20240775","url":null,"abstract":"Background: While visual inspection with acetic acid (VIA) is an effective and affordable screening tool, the determination of the severity of cervical intraepithelial neoplasia (CIN) relies heavily on the expertise of healthcare professionals and the interpretation of colposcopic and biopsy findings. The aim of this study is to compare the frequency CIN I-III in VIA positive cases with the help of colposcopic and biopsy findings.\u0000Methods: The prospective cross sectional descriptive study conducted among the VIA positive cases (n=100) who were attending at in colposcopic clinic of department of obstetrics and gynecology, Dhaka Bangabandhu Sheikh Mujib medical university (BSMMU) during 1st June 2010 to 30th August 2010. History includes present and past illness, personal, family history, drug history and blood pressure were done.\u0000Results: The mean duration of married life was 16.8±10.6 years and more than a half (52.0%) of the patients’ age was 15-20 years of their first intercourse. More than one fourth (27.0%) of the patients had irregular menstrual cycle and 10.0% patients were menopause. Most (72.0%) of the study patients were multipara and the mean age of 'last confinement was 7.8±6.8 years. Majority 38(38.0%) of the patient was normal, 25 (25.0%) of the study patients had CIN I and CIN II in 13 (13.0%), CIN III in 5 (5.0%), 4 (4.0%) had invasive carcinoma and 15 (15.0%) unsatisfactory colposcopy. The colposcopic related biopsy findings was observed, 27.1% of the study patients had CIN I, 12.9% had CIN II, 12.9% invasive carcinoma, 5.9% had CIN III and 5.9% had inflammatory change.\u0000Conclusions: CIN III in colposcopic-related biopsy findings was associated with a mixture of CIN I and CIN III in colposcopic examinations. Invasive carcinoma in biopsy results was linked to a combination of CIN III and invasive carcinoma in colposcopic findings.","PeriodicalId":14225,"journal":{"name":"International journal of reproduction, contraception, obstetrics and gynecology","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140371797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative study of episiotomy suturing using suture material chromic catgut versus Rapide Vicryl and its outcome","authors":"Trupti Ruge, Lathasri A.","doi":"10.18203/2320-1770.ijrcog20240791","DOIUrl":"https://doi.org/10.18203/2320-1770.ijrcog20240791","url":null,"abstract":"Background: Episiotomy is a surgical incision which is made in the perineum to enlarge the vaginal opening for birth, with a purpose to facilitate the completion of the second stage of labour to improve both the maternal and the neonatal outcomes. A significant number of women experience perineal trauma following vaginal deliveries which may result in perineal pain, dyspareunia and faulty healing. The type of suture material which is used, will influence these factors. Objectives were to assess the effect of suture materials (Rapide Vicryl versus catgut) used in episiotomy and evaluate the wound healing characteristics on day 2 and day 7.\u0000Methods: All the pregnant women in labour admitted in labour room of Navodaya medical college, 200 patients satisfying the inclusion and exclusion criteria were taken and were assigned in one of the groups for episiotomy and suturing was done using either of the materials-Vicryl Rapide 2-0 or chromic catgut 1-0, followed up the women in the postnatal ward on day 2 and day 7 and look for immediate complications of episiotomy like temperature, severe pain, hematoma induration, wound gapping and discharge.\u0000Results: Among a total of 200 cases, at 48 hours, there was no significant difference according to the pain measurement scores, but the median consumption of analgesics was significantly lower with fast-absorbing polyglactin 910. There was no difference in the association with dysparenia at 6 weeks after the delivery between chromic catgut (19%) compared with standard polyglactin 910 group (8%).\u0000Conclusions: Fast-absorbing form of polyglactin sutures are preferred over chromic catgut because of their non- allergic properties, increased tensile strength, lesser probability of pain and lower chances of infection.","PeriodicalId":14225,"journal":{"name":"International journal of reproduction, contraception, obstetrics and gynecology","volume":"68 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140368987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the uncommon: invasive adenocarcinoma cervix presenting during pregnancy: a rare case report","authors":"S. R. Tauro, Yanglem A. Singh, Basanti Namoijam","doi":"10.18203/2320-1770.ijrcog20240817","DOIUrl":"https://doi.org/10.18203/2320-1770.ijrcog20240817","url":null,"abstract":"Adenocarcinoma of the cervix presenting during pregnancy is an exceedingly rare occurrence, and the optimal management approach remains uncertain due to limited reported cases. Here we are presenting a case of a multiparous lady who presented with complaints of amenorrhoea for 3 months, pain abdomen, spotting per vaginum, mass felt per vaginum. Ultrasonography showed single live intrauterine pregnancy at 11 weeks 4 days of gestational age with an ill-defined hyperechoic lesion measuring 4.36×4.92×4.16 cm in cervix. HPE of cervical biopsy confirmed cervical adenocarcinoma-endocervical type, grade 2. On MRI, a heterogeneous exophytic irregular mass involving the external os, protruding into the upper vaginal cavity was identified with infiltration into the anterior upper vaginal wall, pelvic lymphadenopathy, and sub-centimetric inguinal lymph nodes were observed. The patient underwent radical hysterectomy with bilateral pelvic lymph node dissection. The surgical specimen exhibited stromal invasion exceeding 5mm in depth and width greater than 7mm, involving entire cervical wall with lympho-vascular space invasion. The tumor was ER/PR negative, strongly positive for P16, and HPV studies were also positive. Adjuvant external beam radiotherapy (EBRT) was administered to the pelvis, and the patient is currently in remission.","PeriodicalId":14225,"journal":{"name":"International journal of reproduction, contraception, obstetrics and gynecology","volume":"133 28","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140369535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}