研究宫内发育受限妊娠对胎儿和母体的影响

Prachi Sharma, Amiya U. Mehta
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摘要

背景:胎儿生长受限(FGR)是指胎儿未达到遗传生长潜能的一种病理状态。与发达国家相比,不发达国家和发展中国家的胎儿生长受限发生率高出 6 倍:这是一项回顾性研究,在艾哈迈达巴德市民用医院和 B. J. 医学院妇产科进行,研究时间为 2022 年 12 月至 2023 年 5 月,为期 6 个月。共研究了 30 例宫内发育受限(IUGR)孕妇:研究对象中,60%属于20-30岁的年轻群体。多胎妊娠与 IUGR 胎儿有关。大多数患者,即 76.66%。孕周≥37周,23.33%的患者孕周<37周。大多数 IUGR 婴儿(73.33%)的出生体重在 2 至 2.5 公斤之间。三分之一的婴儿需要入住新生儿重症监护室,围产期死亡率为 10%。有 27% 的 IUGR 病例出现了脐动脉多普勒变化。在风险因素中,贫血、先兆子痫和少腹水的比例相当,均为 10%。在 16% 的病例中,SGA 胎儿的既往病史与此密切相关。60%的病例进行了引产,63%经阴道分娩,其余通过下段剖腹产(LSCS),LSCS最常见的指征是胎儿窘迫:该研究得出结论,IUGR 仍是导致胎儿发病率和死亡率的主要病因之一,而 LSCS 率的上升则导致了产妇发病率的上升。缺乏产前保健的多胎妊娠患者通常会出现 IUGR。贫血和妊娠高血压疾病以及少尿是导致 IUGR 的潜在风险因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Study of fetomaternal implications in intrauterine growth restriction pregnancies
Background: Fetal growth restriction (FGR) is a pathological condition in which a fetus has not achieved its genetic growth potential. FGR incidence is 6 times higher in underdeveloped and developing countries as compared to the developed world. Methods: This is a retrospective study done in the department of obstetrics and gynaecology, civil hospital and B. J. Medical college, Ahmedabad over the period of 6 months from December 2022 to May 2023. A total of 30 cases of intrauterine growth restriction (IUGR) pregnancies were studied. Results: Majority of the study population, 60% belonged to younger age group of 20-30 years. Multiparity was associated with IUGR babies. Majority of patients i.e. 76.66%. Presented at gestational age of ≥37 weeks and 23.33% at <37 weeks. Most IUGR babies (73.33%) had a birth weight between 2 to 2.5 kg. One third of babies required NICU admission while the perinatal mortality was 10%. Doppler changes in umbilical artery were noted in 27% of cases of IUGR. Among risk factors anemia, preeclampsia and oligohydramnios had equal contributions at 10% each. Previous history for SGA baby is a significant association in 16% of cases. Induction of labor was done in 60% cases, 63% were delivered vaginally and rest via lower segment caesarean section (LSCS), the most common indication of LSCS was fetal distress. Conclusions: The study concluded that IUGR continues to be one of the major etiological factors for fetal morbidity and mortality and increase in rates of LSCS contributing maternal morbidity. IUGR was commonly observed in multigravida patients lacking antenatal care. Anemia and hypertensive disorders of pregnancy as well as oligohydramnios are the potential risk factors for IUGR.
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