有严重特征和无严重特征的先兆子痫患者胎盘早剥的相关性

Rakshith Nagaraj, Hemalatha C. Ramakrishnappa, Anusha B. Chandrashekhar, Swathi L. Iyengar
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摘要

背景:胎盘早剥是导致全球孕产妇和胎儿发病率和死亡率增加的主要原因。目前仍缺乏针对妊娠高血压(PIH)胎盘早剥的研究。本研究旨在重点收集有关胎盘早剥的数据,并客观地确定胎盘早剥对妊娠合并妊娠高血压(PIH)的结局的影响,以改善胎儿和孕产妇的发病率和死亡率:这项回顾性观察研究在迈索尔医学院和研究所(MMCRI)的 Cheluvamba 医院妇产科进行。研究纳入了 2022 年 1 月至 2023 年 8 月期间诊断为胎盘早剥超过 28 周且患有 PIH 的所有孕妇。数据收集自医疗记录部门,并对结果进行了分析:研究期间共有 14027 例分娩。结果:在研究期间,共有 14027 例分娩,其中 63 例(0.44%)为胎盘早剥合并 PIH 患者。平均年龄为 24.57 岁,大多数为多胎妊娠(58.46%),大多数为早产(77.77%)。61.90%的孕妇患有重度子痫前期。平均收缩压(SBP)为 151.90 mmHg,舒张压(DBP)为 98.73 mmHg。65.08%的产妇通过剖腹产分娩。围产期死亡率为 47.61%,围产期窒息率为 45.71%,早产率为 65.71%,出生体重不足率为 84.12%。新生儿重症监护室入院率为 71.42%。产妇并发症包括产后出血(PPH)(31.74%)、需要输血和血制品(63.49%)、凝血功能障碍(14.28%)和休克(12.69%)。4 名产妇在产后出现了严重的子痫前期症状,其中 2 人需要服用硫酸镁。58.73%的产妇在产后需要服用降压药:流产是产科急症之一。在我们的研究中,具有严重特征的先兆子痫会对孕产妇和围产期造成更严重的不良后果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Association of abruptio placenta in patient with pre-eclampsia with severe features and without severe features
Background: Placental abruption is responsible for increased risk of maternal and fetal morbidity and mortality worldwide. Studies specific to placental abruption in pregnancy-induced hypertension (PIH) are still lacking. This study is designed to focus on collecting data on placental abruption and to objectively determine its impact on the outcome of pregnancy complicated with PIH in terms of improving fetal and maternal morbidity and mortality. Methods: This was retrospective observational study conducted at Cheluvamba Hospital, Mysore Medical College and Research Institute (MMCRI), Mysore, in the department of obstetrics and gynaecology. All pregnant women with diagnosis of abruptio placenta over 28 weeks and with PIH between January 2022 to August 2023 were included. Data was collected from medical records department and results were analysed. Results: During the study period there were total of 14027 deliveries. Of this 63 (0.44%) occurred in patients with placental abruption with PIH. Mean age group was 24.57 years; majority were multigravida (58.46%) Majority were preterm (77.77%). 61.90% had pre-eclampsia with severe features. Mean systolic blood pressure (SBP) was 151.90 mmHg, diastolic blood pressure (DBP) was 98.73 mmHg. 65.08% delivered by caesarean section. 47.61% was the perinatal mortality, perinatal asphyxia was 45.71%, prematurity was 65.71%, low birth weight was 84.12%. 71.42% was the neonatal intensive care unit (NICU) admission rate. Maternal complications seen was postpartum haemorrhage (PPH) (31.74%), requiring blood and blood products transfusion (63.49%), coagulopathy (14.28%), shock (12.69%). 4 women developed severe features of pre-eclampsia in postpartum period, 2 of them needed MgSO4. 58.73% had requirement of antihypertensives in postpartum period. Conclusions: Abruption is one of the obstetric emergencies. In our study severe adverse maternal and perinatal outcomes were more pronounced in pre-eclampsia with severe features and it needs an individual and intense surveillance and management to have better maternal and perinatal outcome.
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