International Journal of Research in Medical Sciences最新文献_第6页

Esophageal diverticulum: a case report 食管憩室：病例报告

International Journal of Research in Medical Sciences Pub Date : 2024-03-29 DOI: 10.18203/2320-6012.ijrms20240855

Olga E. Amador, Gabriel Gutierrez, Miguel A. Echeverry, Francisco Ayón, Jessica Esmeralda Miguel Sánchez, Cruz Alberto Tirado, Faustino Rubio Soto, Arturo Ramos Ruelas

引用次数: 0

A rare nexus: G6PD deficiency's uncommon affiliation with rapidly progressive renal failure through the prism of pigment nephropathy 罕见的联系：从色素肾病的角度看 G6PD 缺乏症与快速进展性肾衰竭的罕见关联

International Journal of Research in Medical Sciences Pub Date : 2024-03-29 DOI: 10.18203/2320-6012.ijrms20240861

Ayush Thakur, Vandana Admane, P. Jawandhiya, Shital Bahekar, Akshay Jaiswal

{"title":"A rare nexus: G6PD deficiency's uncommon affiliation with rapidly progressive renal failure through the prism of pigment nephropathy","authors":"Ayush Thakur, Vandana Admane, P. Jawandhiya, Shital Bahekar, Akshay Jaiswal","doi":"10.18203/2320-6012.ijrms20240861","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240861","url":null,"abstract":"Acute kidney injury (AKI) with evidence of hemolysis is associated with tropical infections. However, pigment-induced AKI can happen with relatively uncommon genetic causes of hemolytic anemia, i.e., glucose 6-phosphate deficiency (G6PD). We share our experience of one such patients whose clinical presentation was rapidly progressive glomerulonephritis. On evaluation, she had a history of usage of some drugs and with G6PD estimation revealing deficient status even during the episode while other tests such as Coomb's test and bone marrow biopsy was normal. The kidney biopsy revealed diffuse tubular injury with presence of several coarse granular/pigmented casts in tubular lamina. She was managed with hemodialysis and showed complete recovery. Thus, in tropical countries G6PD deficiency although is not common, should be considered among patients who presented as rapidly progressive renal failure (RPRF) and having history of precipitating factors for G6PD deficiency and a detailed hemolytic work-up needs to be carried out as an important cause of preventable recurrent AKI in tropical countries.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"30 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140365973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinico-pathological profile of breast cancer patients in a radiation therapy centre 放射治疗中心乳腺癌患者的临床病理特征

International Journal of Research in Medical Sciences Pub Date : 2024-03-29 DOI: 10.18203/2320-6012.ijrms20240831

M. M. Rahman, M. J. Shams, Mostafa Sanaul Haque, Shourov Biswas

{"title":"Clinico-pathological profile of breast cancer patients in a radiation therapy centre","authors":"M. M. Rahman, M. J. Shams, Mostafa Sanaul Haque, Shourov Biswas","doi":"10.18203/2320-6012.ijrms20240831","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240831","url":null,"abstract":"Background: The aim of the study was to evaluate the clinico-pathological characteristics of patients with breast cancer at the Radiation Center of Bangabandhu Sheikh Mujib Medical University (BSMMU), a tertiary‑care cancer center in Dhaka, Bangladesh. \u0000Methods: This descriptive study was conducted from March 2021 to February 2022 where patients receiving radiotherapy for breast cancer were included. Data were collected from face-to-face interviews with patients and from their investigation reports. Data regarding age, presenting symptoms, histological type, tumor size, involvement of regional nodes, hormonal receptor status, and human epidermal growth factor receptor 2 (HER2) amplification were recorded and then analyzed.\u0000Results: The mean age of the patients was 52.53 years. Most of the patients (93%) were multiparous and 62.24% were postmenopausal. The most common symptom was breast lump (91.6%). Infiltrating ductal carcinoma and lobular carcinoma were seen in 136 (95.1%) and 7 (4.9%) cases respectively. The TNM stage distribution was stage I, 6 (4.2%); stage II, 52 (36.36%); stage III, 76 (53.15%); and stage IV, 9 (6.29%). Locally advanced breast cancer constituted 42.66% of the cases. Among the patients 90 (62.94%) patients were ER/PR positive and 42 (29.37%) patients were HER2 positive. Triple negative breast cancer (TNBC) constituted 25.17% (36) of the study population. All receptors were positive in 25 patients (17.48%).\u0000Conclusions: Majority of our patients receiving breast radiotherapy at our center are middle aged and have advanced disease. TNBC and HER2 positive breast cancer are more common in our population.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"11 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140366783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The universal immunization programme coverage and determining factors among tribal children under the age of five in the Wayanad district of Kerala, South India 印度南部喀拉拉邦 Wayanad 地区五岁以下部落儿童的全民免疫计划覆盖率和决定因素

International Journal of Research in Medical Sciences Pub Date : 2024-03-29 DOI: 10.18203/2320-6012.ijrms20240842

Arun Krishna S. R., H. A. S., Kalpana S.

{"title":"The universal immunization programme coverage and determining factors among tribal children under the age of five in the Wayanad district of Kerala, South India","authors":"Arun Krishna S. R., H. A. S., Kalpana S.","doi":"10.18203/2320-6012.ijrms20240842","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240842","url":null,"abstract":"Background: Globally an estimated two to three million deaths occur every year in all age groups, from six major vaccine-preventable diseases and accounts for almost a quarter of all deaths in children under the age of five years. As Immunization is one of the most successful and cost-effective methods for preventing infectious diseases, the Indian government initiated a vaccination programme to reduce infant mortality and morbidity owing to vaccine-preventable diseases, and achieve vaccine self-sufficiency. In Kerala, about 1.5% of the total population makes up Scheduled Tribes, a socioeconomic group with continuously poor health indicators.\u0000Methods: Through a community-based cross-sectional study using cluster sampling technique, this study intends to determine the coverage of the universal immunization programme among tribal children (0-59 months), the factors affecting vaccination coverage as well as the reasons for partial immunization in Noolpuzha Panchayat, Wayanad. A semi-structured questionnaire was used to collect information from caregivers/mothers.\u0000Results: Out of 289 study population, 64.4% were fully immunized and 35.6% were partially immunized. Children's age and the father's education were found to affect immunization.\u0000Conclusions: As a lack of knowledge about immunizations and subsequent doses was the primary reason for partial immunization. There is a need to create awareness about the importance of vaccination and the subsequent doses among the tribal people of Wayanad.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"4 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140367260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A rare cause of epididymo-orchitis 附睾睾丸炎的罕见病因

International Journal of Research in Medical Sciences Pub Date : 2024-03-29 DOI: 10.18203/2320-6012.ijrms20240862

S. B. Patil, B. Patil, Santosh Patil, V. Kundargi, Nawaz A. Shariff

引用次数: 0

Zollinger-Ellison syndrome: case report and topic review 佐林-艾利森综合征：病例报告和专题综述

International Journal of Research in Medical Sciences Pub Date : 2024-03-29 DOI: 10.18203/2320-6012.ijrms20240856

Rosaura J. Serrano, Kevin Avilés, Yanetzy E. Corona, Gaby A. Alarcón

{"title":"Zollinger-Ellison syndrome: case report and topic review","authors":"Rosaura J. Serrano, Kevin Avilés, Yanetzy E. Corona, Gaby A. Alarcón","doi":"10.18203/2320-6012.ijrms20240856","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240856","url":null,"abstract":"Zollinger-Ellison syndrome (ZES) is characterized by gastrin-secreting neuroendocrine tumors (gastrinomas) in the duodenum or pancreas. It is a rare condition, most patients are diagnosed between the ages of 20 and 50, and a higher incidence in men. Gastrinomas are associated with a high risk of malignancy and the diagnosis is confirmed by the secretin stimulation test and imaging studies such as octreotide scintigraphy. We present the case of a 24-year-old man who presented with melena, asthenia, adynamia and abdominal pain, in addition to a history of peptic ulcer. Laboratory tests revealed low levels of hemoglobin and elevated levels of gastrin. Endoscopy showed a giant ulcer and subsequent surgery revealed stomach-jejunum adhesions, gastric lesions and Meckel's diverticulum. Imaging studies confirmed neuroendocrine tumor activity in the pancreas. ZES leads to sustained hypergastrinemia, causing peptic ulcers and other digestive tract complications. Gastrinomas can arise from a variety of locations and can cause peptic ulcers, malabsorption, and diarrhea. Diagnosis requires elevated fasting serum gastrin levels and hypersecretion of gastric acid. Treatment involves discontinuation of proton pump inhibitors (PPIs) before diagnostic testing and surgical resection of tumors in suitable candidates. The diagnosis of ZES can be complicated due to the unreliability of the assays and the need for secretin testing. Surgical resection is recommended for sporadic gastrinomas without metastasis, while medical treatment may be necessary for postsurgical residual hyperacidity. Patients should undergo imaging studies for tumor localization and regular monitoring for complications and recurrences.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"29 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140368164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of rifaximin among non-constipated irritable bowel syndrome patients with or without small intestinal bacterial overgrowth: a randomized, double-blind, placebo-controlled trial 利福昔明对伴有或不伴有小肠细菌过度生长的非便秘型肠易激综合征患者的疗效：随机、双盲、安慰剂对照试验

International Journal of Research in Medical Sciences Pub Date : 2024-03-29 DOI: 10.18203/2320-6012.ijrms20240825

S. Podder, M. Masudur Rahman, M. I. Hossain, R. Datta, Jane Alam, M. Golam Kibria

{"title":"Efficacy of rifaximin among non-constipated irritable bowel syndrome patients with or without small intestinal bacterial overgrowth: a randomized, double-blind, placebo-controlled trial","authors":"S. Podder, M. Masudur Rahman, M. I. Hossain, R. Datta, Jane Alam, M. Golam Kibria","doi":"10.18203/2320-6012.ijrms20240825","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240825","url":null,"abstract":"Background: IBS is a functional gastrointestinal disorder marked by abdominal pain and changes in stool frequency or form. Recent studies indicate a link between IBS, especially the diarrhea-predominant subtype, and small intestinal bacterial overgrowth. This study aimed to evaluate symptom resolution among IBS patients with or without SIBO on rifaximin treatment as compared with placebo.\u0000Methods: A double-blind, placebo-controlled, randomized clinical trial took place at the Department of Gastroenterology, Dhaka Medical College and Hospital, from January to December 2019. In the study 104 non-constipated IBS patients were assessed for SIBO using gut aspirate culture. Those with SIBO (≥105 CFU/ml) and those without were randomly assigned (computer-generated) to receive either 1500 mg/day of rifaximin for 14 days or a placebo.\u0000Results: Among 104 non-constipated IBS patients, 39% had SIBO, with IBS-D patients more associated (83% vs. 60%). Rifaximin significantly improved symptoms in the SIBO group at 4 and 16 weeks (90% vs. 20%, p<0.001; 66% vs. 15%, p<0.001). In the non-SIBO group, significant improvement was observed at 4 weeks (38.7% vs. 18.8%, p<0.001) but not at 16 weeks (25.8% vs. 18.8%, p=0.501). Rifaximin significantly improved abdominal pain, stool form, and frequency in the SIBO group compared to placebo. However, there was no significant improvement in the non-SIBO group.\u0000Conclusions: Rifaximin is superior to placebo in relieving symptoms of non-constipated IBS patients with SIBO.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"64 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140365149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mature cystic teratoma of anterior mediastinum: a case report 前纵隔成熟性囊性畸胎瘤：病例报告

International Journal of Research in Medical Sciences Pub Date : 2024-03-29 DOI: 10.18203/2320-6012.ijrms20240863

C. Anusha, P. S. S. Gopal

引用次数: 0

A case of abdominal tuberculosis presenting as obstructive jaundice 一例表现为阻塞性黄疸的腹腔结核病例

International Journal of Research in Medical Sciences Pub Date : 2024-03-29 DOI: 10.18203/2320-6012.ijrms20240857

Suresh Naik, B. Kulkarni, Siddhant Shrotriya, Kirankumar B. Ghade

引用次数: 0

Yolk sac tumor in children and the resulting biopsychosocial and spiritual aspects 儿童卵黄囊肿瘤及其导致的生物、心理、社会和精神方面的问题

International Journal of Research in Medical Sciences Pub Date : 2024-03-29 DOI: 10.18203/2320-6012.ijrms20240850

Hidayatullah, Irma Savitri, Lenny Lisal

{"title":"Yolk sac tumor in children and the resulting biopsychosocial and spiritual aspects","authors":"Hidayatullah, Irma Savitri, Lenny Lisal","doi":"10.18203/2320-6012.ijrms20240850","DOIUrl":"https://doi.org/10.18203/2320-6012.ijrms20240850","url":null,"abstract":"Yolk sac tumor is a rare germ cell tumor in children, accounting for only about 3.5% of pediatric cancers. However, the yolk sac tumor is a malignant tumor that requires chemotherapy, but the side effects of chemotherapy can have an impact on the biopsychosocial and spiritual aspects of the child. This case report presents the negative impacts on the biopsychosocial and spiritual aspects of a child diagnosed with a yolk sac tumor. 11-year-old girl experienced symptoms of an enlarged abdomen, feeling bloated, pain, and frequent urination. The pathological examination revealed a yolk sac tumor, and the examination of ascites showed malignant cells. The patient was diagnosed with a yolk sac tumor, Stage 1C3, and was to undergo chemotherapy. She scored 15, indicating that the patient experienced anxiety due to the yolk sac tumor diagnosis and was anxious about the side effects of chemotherapy. Examination of the biological, psychological, social, and spiritual aspects in pediatric patients with a yolk sac tumor can assist in addressing the adverse effects of the diagnosis and the anxiety about chemotherapy in a more comprehensive manner.","PeriodicalId":14210,"journal":{"name":"International Journal of Research in Medical Sciences","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140367508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0