{"title":"Hepatoprotective Effect of an Antrodia cinnamomea Product Via a Novel Process on Carbon Tetrachloride-Induced Hepatotoxicity in Rats","authors":"H. Hsiao, Y. Weng","doi":"10.11648/J.IJNFS.20180704.14","DOIUrl":"https://doi.org/10.11648/J.IJNFS.20180704.14","url":null,"abstract":"Antrodia cinnamomea , causing a brown heart rot of Cinnamomum kanehirai Hay. endemic to Taiwan, was reported to have several biological activities for treating liver diseases, inflammation, tumors, et al . It was believed that wild or wood-cultured A.cinnamomea on C.kanehirai Hay. was better than by other means. However, C.kanehirai Hay. was rare and expensive, that resulted in a higher price of wild or wood-cultured A.cinnamomea . Hence, a novel process was developed to spray solid-state-cultured A.cinnamomea extracts on wood-cultured A.cinnamomea powder to make a high quality and low price product. The purpose of the study was to evaluate its hepatoprotection against carbon tetrachloride-induced hepatotoxicity in rats. Results revealed that aspartate aminotransferase (AST) and alanine aminotransferase (ALT) of Sprague Dawley rats administered 20% carbon tetrachloride (CCl 4 ) twice a week, when the rats was also administered 413.4 or 1033.5 mg/kg body weight (BW) A.cinnamomea daily for 8 weeks, were significantly reduced in serum. Administration of 1033.5 mg/kg BW A.cinnamomea daily would not only reduce the rats’ liver and spleen swelling, liver fibrosis, and level of hydroxyproline, but increase activities of superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, and glutathione. In conclusion, the A.cinnamomea product via the novel process at 1033.5 mg/kg BW had hepatoprotective effects on carbon tetrachloride-induced hepatotoxicity in rats.","PeriodicalId":14174,"journal":{"name":"International Journal of Nutrition and Food Sciences","volume":"40 1","pages":"134"},"PeriodicalIF":0.0,"publicationDate":"2018-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80151514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Determination of 19 Organochlorine Pesticides Residues in Milk Powder by GPC-GC-MS","authors":"Zhao-hui Wu, Xiao-Jin Peng, Sheng-Min Chen, Zhan-jun Zeng","doi":"10.11648/J.IJNFS.20180704.13","DOIUrl":"https://doi.org/10.11648/J.IJNFS.20180704.13","url":null,"abstract":"To establish the GPC - GC - MS detection method for determination of organochlorine pesticide residues in milk powder. After simple processing samples, concentration with multi-position concentrator, and online cleaning with GPC-GC-MS, injection into the mass spectrometer for analysis. Results showed that in the linear range of 5~100 ug/L, the correlation coefficient were >0.998, and the method detection limits (MDLs) were <0.5 ug/kg. The spiked recoveries at three levels of 10, 50, 100 ug/kg were in the range of 70 ~ 95%, the relative standard deviations (RSDs) (n=6) were<10%. This method had advantages of good accuracy and precision, simple operation, rapid, and was suitable for routine analysis.","PeriodicalId":14174,"journal":{"name":"International Journal of Nutrition and Food Sciences","volume":"31 1","pages":"129"},"PeriodicalIF":0.0,"publicationDate":"2018-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85086993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah I. Iyalomhe, Samuel Esiemokhai Iyalomhe, I. Nwadike, Rosemary Ngozi Osunde, G. Iyalomhe
{"title":"Assessment of Dietary Habits and Nutritional Status of Adolescents in a Resource – Poor Environment in Nigeria","authors":"Sarah I. Iyalomhe, Samuel Esiemokhai Iyalomhe, I. Nwadike, Rosemary Ngozi Osunde, G. Iyalomhe","doi":"10.11648/J.IJNFS.20180704.12","DOIUrl":"https://doi.org/10.11648/J.IJNFS.20180704.12","url":null,"abstract":"Information is scarce about dietary habits and nutritional status in adolescents in Ekpoma, Nigeria. This is partly because of this age group’s reputation for capriciousness and also because health services/research in developing countries tend to focus more on pre-school children and pregnant women. This study aimed to optimize the health needs of Nigerian adolescents by determining the dietary habits and the nutritional status of adolescents using anthropometry. The cross-sectional descriptive study engaged 400 adolescents aged 10 - 19 years in four secondary schools in Ekpoma using a semi-structured questionnaire for data collection. Height (m 2 ) and weight (kg) were measured and body mass index (BMI) was computed to assess underweight, normal weight, over-weight or obesity. SPSS was used to analyse data. Important factors affecting dietary habits include parental influence (87%), taste of food (71%), mass media reports (61%) and culture (55%). Percentages of underweight, normal weight, overweight, and obese adolescents were 24%, 72%, 3% and 1%, respectively. There was significant association between BMI and monthly household income, p<0.002. There were no significant gender differences. In contrast to the rising prevalence of obesity worldwide, this study has demonstrated that under-nutrition is a challenge in this environment. Intensified nutritional education, provision of adequate healthy diets and motivational strategies are imperatives to prevent malnutrition and its related health consequences in this adolescent population – tomorrow’s adults.","PeriodicalId":14174,"journal":{"name":"International Journal of Nutrition and Food Sciences","volume":"12 1","pages":"121"},"PeriodicalIF":0.0,"publicationDate":"2018-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90951816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Viability of Probiotics in Frozen Yogurt Supplemented with Inulin and Glycerol","authors":"Hafiz Shehzad Muzammil, B. Rasco, M. Junaid","doi":"10.11648/j.ijnfs.20180704.11","DOIUrl":"https://doi.org/10.11648/j.ijnfs.20180704.11","url":null,"abstract":"To evaluate the effect of inulin and glycerol supplementation on the viability of probiotic and yogurt bacterial cultures in frozen yogurt, this study was conducted. The frozen yogurt mixture was prepared with different types of probiotics ( Lactobacillus acidophilus and Bifidobacterium lactis ) along with commercial yogurt starter culture ( Streptococcus thermophilus and Lactobacillus bulgaricus ). Different concentrations of inulin (2%, 4%, and 6%) and glycerol (1%, 2%, 3%, and 4%) were also supplemented. The cultural survival rates before and after freezing and with 3 weeks regular intervals up to 12 weeks were examined. The viability loss during freezing process of S. thermophilus and L. bulgaricus were recorded 0.2-0.3 log cycles. While, in probiotic cultures this was observed 0.2-0.5 log cycles in L. acidophilus and 0.1-0.2 log cycles in B. lactis concentration. The glycerol 4% supplementation in this study has shown most significant improvement in viability (P<0.05).","PeriodicalId":14174,"journal":{"name":"International Journal of Nutrition and Food Sciences","volume":"25 1","pages":"116"},"PeriodicalIF":0.0,"publicationDate":"2018-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90461267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tamiru Kasaye Atlaw, Jha Yogesh Kumar, N. Satheesh
{"title":"Effect of Germination on Nutritional Composition and Functional Propertiesof Fenugreek ( Trigonellafoenum-graecumLinn ) Seed Flour","authors":"Tamiru Kasaye Atlaw, Jha Yogesh Kumar, N. Satheesh","doi":"10.11648/J.IJNFS.20180703.15","DOIUrl":"https://doi.org/10.11648/J.IJNFS.20180703.15","url":null,"abstract":"This study evaluated the effect of germination on the chemical composition and functional properties of fenugreek seed flour. The study was conducted at Addis Ababa Institute of Technology in Food Engineering laboratory. Fenugreek seed was germinated for 0, 24, 48 and 72 hrs. Germinated fenugreek flour had higher crude protein 29.89% in fenugreek flour germinated for 72 hrs followed by 29.36% in fenugreek flour germinated for 48 hrs and 27.42% in raw fenugreek flour. The crude fiber ranged from 11.349 to 14.70%. But as the time of germination increased the crude fiber content slightly decreased. Fenugreek flour germinated for 48 hrs proved to be more beneficial in most mineral content than the rest of the germination periods (p<0.05). Germinated fenugreek flour for 72 hrs had significantly lower contents of anti-nutritional factors. The phytate content decreased significantly (p<0.05) from 64.22 to 18.99 with 53.96% reduction. The study showed that fenugreek flour germinated for 72h proved to be the best for highest nutrient content. The reduction of bulk density further increased as germination time increased. The control fenugreek flour have higher amount of water absorption capacity (401.86%). On germination the water absorption capacity decreased to 250.07, 248.13, and 245.15% at 24, 48, 72 hrs germination, respectively. The processed fenugreek flour had a higher oil absorption capacity in the range of 346.13-398.40 ml/g, which was significantly (p<0.05) higher than that of control flour. Therefore, the use of processed fenugreek seed flour can be exploited in functional foods as well as a therapeutic agent on a regular basis.","PeriodicalId":14174,"journal":{"name":"International Journal of Nutrition and Food Sciences","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88514901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hagan Lynda Larmkie, Johnson Paa-Nii Torgbor, O. Mary, Blay Adjei Maame Yaa, S. Christopher, Dzomeku Matilda
{"title":"Sensory Attributes of Three Edible Tropical Mushrooms and Their Use in Formulating Food Products for Children 2 -5 Years Old","authors":"Hagan Lynda Larmkie, Johnson Paa-Nii Torgbor, O. Mary, Blay Adjei Maame Yaa, S. Christopher, Dzomeku Matilda","doi":"10.11648/J.IJNFS.20180703.14","DOIUrl":"https://doi.org/10.11648/J.IJNFS.20180703.14","url":null,"abstract":"Background : Mushrooms are important sources of proteins and vitamins, but have unique sensory properties in appearance, flavour and texture that can lead to polarized liking amongst consumers. Children between the ages of 2 to 5 years can be picky eaters and adding vegetables such as mushrooms into their diets can be a challenge. Objective : This study involved the development of mushroom-based food products acceptable to children within this age bracket through a stepwise approach. Materials and Methods : Sensory attributes of three tropical edible mushrooms, Pleurotus ostreatus (EMI), Pleurotus sajor-caju (PSCW) and Auricularia ssp. (ART), were characterized using quantitative descriptive analysis (QDA), using 30 descriptors. The QDA revealed that all three mushrooms differ distinctly from each other in appearance, mouthfeel and aftertaste. The aroma and flavour profiles of EM1 and PSCW mushrooms were comparable. From the QDA, EMI and PSCW were selected and used to formulate six mushroom-based food prototypes; three of which included cereals and the other three had orange–flesh yellow potato flour as main components. The 6 prototype foods were then assessed by three sets of focus groups of caregivers and mothers on the suitability of using the mushrooms in the preparation of foods for children of the target age. Two mushroom-based food products, one with cereal blends and the other with 30% orange flesh yellow potato flour were further subjected to consumer-liking tests involving 83 children 2-5 years old. and this final test established the mushrooms can be incorporated into children’s diet. Conclusion : The study established two of the mushrooms could be used as flavourant; EMI mushroom suitable for fish or savory-flavoured products whilst the PSCW mushroom was preferred for nutty-flavoured products and these two when used in mushroom-based foods were highly acceptable to children 2 to 5 year old.","PeriodicalId":14174,"journal":{"name":"International Journal of Nutrition and Food Sciences","volume":"12 1","pages":"100"},"PeriodicalIF":0.0,"publicationDate":"2018-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82329613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Yamashita, N. Shimamoto, Kyoko Morita, H. Sugiyama, M. Kimoto, K. Toda, M. Ota
{"title":"Thiamine and Quinine Differently Inhibit the Early Phase of Acetylcholine-Dependent Contraction of Mouse Ileum in vitro","authors":"A. Yamashita, N. Shimamoto, Kyoko Morita, H. Sugiyama, M. Kimoto, K. Toda, M. Ota","doi":"10.11648/J.IJNFS.20180703.13","DOIUrl":"https://doi.org/10.11648/J.IJNFS.20180703.13","url":null,"abstract":"Thiamine and quinine are popular bitter substances and their physiological effects have been studied; however, their impact on digestion remains unknown. Here, the physiological effects of thiamine and quinine was investigated for in vitro contraction of mouse ileum. Acetylcholine stimulates autonomous contraction of mouse ileum in a dose-dependent manner. The effect of Acetylcholine for contraction of ileum was partly suppressed by the adrenaline administration. Upon simultaneous treatment of the ileum by acetylcholine, thiamine, and quinine decreased the maximum contraction. The period till half maximum contraction was prolonged by the presence of thiamine and quinine but not by adrenaline. Because a physiological effect of thiamine and quinine was observed on acetylcholine-induced contraction of the ileum, the repertoire of human bitter taste receptors, TAS2R-1, -4, -7, -10, -14, -31, -39, -40, -43, and -46, were investigated to which thiamine and quinine may bind. These human bitter taste receptors were further analyzed among the database for mouse homologs using evolutionally conserved amino acid sequences. The only bitter receptor for both thiamine and quinine was TAS2R-39, the homology of TAS2R-139 to human TAS2R-39 was 74%. Importantly, the homology of mouse TAS2R-119 to human TAS2R-1 which interact with thiamine was 91%, and that of TAS2R-130 to human TAS2R-7 that interact with quinine was 81%. The present study indicated that thiamine and quinine changed the early phase of contraction of ileum in mice and suggested that TAS2R119 and TAS2R130 expressed in mouse enteroendocrine cells to modify the physiological effects of thiamine and quinine on the acetylcholine-induced contraction of the ileum.","PeriodicalId":14174,"journal":{"name":"International Journal of Nutrition and Food Sciences","volume":"1 1","pages":"94"},"PeriodicalIF":0.0,"publicationDate":"2018-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83081148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Trend Analysis on Maternal Health Care Services Utilization in Amhara Region Referral Hospitals, Ethiopia","authors":"Genanew Timerga, Solomon Hailemeskel","doi":"10.11648/J.IJNFS.20180703.11","DOIUrl":"https://doi.org/10.11648/J.IJNFS.20180703.11","url":null,"abstract":"According to World Health Organization (WHO) repot complications arising during pregnancy death accounts 580,000 women of reproductive age each year, and a high proportion of these deaths contributed in sub-Saharan Africa. Impediments to the effective delivery care, ANC and PNC include geographical, financial and cultural barriers. The objectives of this study were to assess the current status of maternal health care services, compared to previous data factors that influence the utilization of these services, and to investigate trend analysis of improvement of utilization of maternal health care services in Amhara region, Ethiopia. Institution based cross sectional study design was conducted in Amhara region referral hospitals from January 2016 to December 2016. Maternal health care service providers in the respective health facilities collected primary and secondary data using structured and semi structured questionnaire. Odds Ratios, Bivariate and Multivariate logistic regression were used to identify predictor variables associated with the dependent variables. A total of 415 primary data and different samples in different year for secondary data were completed and making utilization of Antenatal Care (ANC), Delivery Care (DC) and Postnatal Care (PNC) services in 2000 to 2016 was found to be the children birth order of 1 mothers (primipara) (21.8%, 18.2%, 15.5% and 65.8%), (18.4%, 18.4%, 15.5% and 50.1%) and (31.7%, 33.4%, 14.4% and 54.9%) with respective years. Women residing in urban areas were 1.5, 1.7, 1.2 and 1.5 times more likely than women in rural areas to receive ANC from a health professional in respective years. Almost all predicted response CI out of covering 1 implies that there was an effect of the factor under consideration. Birth order (gravidity), residence, mothers’ education and wealth index in explaining the utilization of maternal health care services confirmed both bivariate and multivariate analyses significant effect in every year.","PeriodicalId":14174,"journal":{"name":"International Journal of Nutrition and Food Sciences","volume":"37 1","pages":"81"},"PeriodicalIF":0.0,"publicationDate":"2018-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81697941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors Affecting Consumers’ Choice in Consumption of Organic Vegetables and Methods Used to Avoid Consumption of Unhealthy Foods in Tanzania","authors":"W. Kawemama, J. Mugula, Alexander Wostry, J. Maro","doi":"10.11648/j.ijnfs.20180702.15","DOIUrl":"https://doi.org/10.11648/j.ijnfs.20180702.15","url":null,"abstract":"In the previous decades, there has been an upsurge of use of pesticides on food produces. Many consumers now perceive or are knowledgeable that consumption of organic vegetables is healthier than consuming their corresponding items. A cross sectional study was done to assess the factors affecting consumers’ choice in consumption of organic vegetables and methods used to avoid consumption of unhealthy foods in Morogoro and Kinondoni municipalities. A total of 200 paticipants half from each segment were interviewed using a constructed and pretested structured questionnaire. However, the analysis was done to 192 residents, half from each study segment. Data analysis was done through SPSS version 20. Scale liability was tested with Cronbach alpha. Multiple regression analysis was conducted to determine factors that affected the consumers’ choice and identify as well as the approaches used by them to avoid the consumption of unhealthy foods. To avoid consumption of foods that were perceived perilous, physical appearance was a common method used by most (52%, β = 0.493) consumers compared to reading product labels (45.3%, β = 0.296), asking product information (38%, β = 0.434) and product tasting (26%, β = 0.146). The low purchasing and consumption rates of organic vegetables were significantly different (P< 0.05), affected by their perceived low shelf life (β = 0.108), lack of uniqueness (β = 0.071) and unavailability in the market (β = 0.032). Most organic food growers (97%) needed an external participatory guarantee system for liable market so that producers and investors cooperate with organic growers for business-oriented aspects.","PeriodicalId":14174,"journal":{"name":"International Journal of Nutrition and Food Sciences","volume":"39 1","pages":"71"},"PeriodicalIF":0.0,"publicationDate":"2018-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87121385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Islam, Tarek Hasan, N. Lina, Fatematujjohra, Shovon Al-Fuad, R. Roy
{"title":"Assessment of Nutritional Status and Its Determinants Among Pre-School Children Within Dalit Communities of Jessore City in Bangladesh: A Cross-Sectional Study","authors":"A. Islam, Tarek Hasan, N. Lina, Fatematujjohra, Shovon Al-Fuad, R. Roy","doi":"10.11648/J.IJNFS.20180702.14","DOIUrl":"https://doi.org/10.11648/J.IJNFS.20180702.14","url":null,"abstract":"Background : The socio-religiously considered low class Dalit communities are living below extreme poverty line in Bangladesh. They face discrimination at all levels of social interactions. Lack of access to education, extreme poverty issues, health and housing problems, and unequal access to work and employment may put this underprivileged community at the risk of malnutrition. Objectives : This study was carried out to determine the nutritional status and associated factors among preschool children within various Dalit communities in Jessore city, Bangladesh. Study Design : A cross sectional study was undertaken among 165 pre-school children (24-60 months) randomly selected from different Dalit families living in Jessore city, Bangladesh. Anthropometric methods and a structured questionnaire were used to collect the required data. WHO based anthropometric Z scores and MUAC (Mid Upper Arm Circumference) indicators were used to measure nutritional status of the children. Data analysis at 5% level of significance was performed by Statistical Package for Social Science (SPSS)-22 software. Results : About 58% and 45% of the studied preschool children were stunted and underweight respectively while 22.5% children were wasted. Nearly 8.5% children were obese or at risk of being obese. Most of the parents were illiterate or just completed only primary education. Mother and father education status was not statistically significant with stunting, wasting and underweight status of pre-school children. Moderate and severe stunting were relatively higher among younger children (p Conclusions : About half of preschool children among Dalit communities in Jessore city live with chronic malnutrition like stunting and underweight. Maternal health status as well as other socio-demographic factors can affect the nutritional status of children.","PeriodicalId":14174,"journal":{"name":"International Journal of Nutrition and Food Sciences","volume":"33 1","pages":"65"},"PeriodicalIF":0.0,"publicationDate":"2018-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88008523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}