International journal of MS care最新文献_第6页

Mapping Resilience: Structural Equation Modeling of Psychological Resilience in Multiple Sclerosis Care Partners. 映射弹性:多发性硬化症护理伙伴心理弹性的结构方程模型。

International journal of MS care Pub Date : 2023-11-01 Epub Date: 2023-11-08 DOI: 10.7224/1537-2073.2023-078

Katherine L Cardwell, Laura Koch, Odessa J McKenna, Lara A Pilutti, Afolasade Fakolade

{"title":"Mapping Resilience: Structural Equation Modeling of Psychological Resilience in Multiple Sclerosis Care Partners.","authors":"Katherine L Cardwell, Laura Koch, Odessa J McKenna, Lara A Pilutti, Afolasade Fakolade","doi":"10.7224/1537-2073.2023-078","DOIUrl":"10.7224/1537-2073.2023-078","url":null,"abstract":"Background: Care partners are essential supports to individuals with multiple sclerosis (MS). Both negative and positive outcomes associated with the caregiving role have been reported. Psychological resilience may be an important factor influencing the MS caregiving experience, but an MS-specific model of care partner resilience has yet to be established. This study sought to explore an explicit model of MS care partner resilience.Methods: Cross-sectional data from 471 Canadian MS care partners were collected via an online survey. Confirmatory factor analysis (CFA) and structural equation modeling (SEM) were used to test measures within a hypothesized model of resilience. Resilience was measured using the 25-item Connor-Davidson Resilience Scale.Results: Following CFA, the hypothesized model was simplified due to the poor fit of several variables. The final model yielded a moderate SEM fit (χ2 = 6030.95, P < .01). Being a woman was associated with greater caregiving tasks (β = 0.53, P < .001) and poorer spiritual health (β = -0.35, P < .001). Spiritual health, but not caregiving tasks, had a positive impact on both positive (β = 0.48, P < .01) and negative coping (β = 0.49, P = .01). Quality of life and resilience did not have relationships with other variables in the model. However, quality of life had a positive, unidirectional influence on resilience (β = 0.83, P < .01).Conclusions: Our findings indicate that spiritual health is an important predictor of coping and should be further explored in MS care partners. Quality of life may act as a precursor to resilience within MS care partners. Further research and exploration into MS care partner resilience is warranted to confirm this exploratory model.","PeriodicalId":14150,"journal":{"name":"International journal of MS care","volume":"25 6","pages":"245-251"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134648930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Opportunities in Multiple Sclerosis Care Partner Research: An Interview. 多发性硬化症护理合作伙伴研究的机会:访谈。

International journal of MS care Pub Date : 2023-11-01 Epub Date: 2023-11-08 DOI: 10.7224/1537-2073-25.6.278

Marcia Finlayson, Kenneth Pakenham

{"title":"Opportunities in Multiple Sclerosis Care Partner Research: An Interview.","authors":"Marcia Finlayson, Kenneth Pakenham","doi":"10.7224/1537-2073-25.6.278","DOIUrl":"https://doi.org/10.7224/1537-2073-25.6.278","url":null,"abstract":"Guest editor Marcia Finlayson, PhD, OT Reg (Ont), OTR, is a professor in the School of Rehabilitation Therapy at Queen's University in Ontario, Canada. She began her career as a clinical occupational therapist and shifted to a research career focused on generating and sharing knowledge to help people affected by multiple sclerosis (MS) lead healthy, meaningful lives with control over their participation in daily activities, at home and in the community, particularly as they age. For this special issue on caregiving in MS, she chose to interview Kenneth Pakenham, PhD, emeritus professor of clinical and health psychology at the University of Queensland in Brisbane, Australia. For more than 4 decades, he has investigated the psychological well-being welle-eing of caregivers, including coping mechanisms and innovative interventions to improve their quality of life. His work is dedicated to applying positive health frameworks to chronic illnesses and to empowering caregivers and individuals with MS. Together, their expertise illuminates the multifaceted challenges and opportunities in MS caregiving research and understanding.","PeriodicalId":14150,"journal":{"name":"International journal of MS care","volume":"25 6","pages":"278-280"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134650854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Supportive Interventions for Caregivers of Individuals With Multiple Sclerosis: A Systematic Review. 多发性硬化患者护理人员的支持性干预：一项系统综述

International journal of MS care Pub Date : 2023-11-01 Epub Date: 2023-11-08 DOI: 10.7224/1537-2073.2022-083

Fatemeh Hoseinpour, Setareh Ghahari, Fatemeh Motaharinezhad, Maryam Binesh

{"title":"Supportive Interventions for Caregivers of Individuals With Multiple Sclerosis: A Systematic Review.","authors":"Fatemeh Hoseinpour, Setareh Ghahari, Fatemeh Motaharinezhad, Maryam Binesh","doi":"10.7224/1537-2073.2022-083","DOIUrl":"10.7224/1537-2073.2022-083","url":null,"abstract":"Background: Caregivers of individuals with multiple sclerosis (MS) are key members of the treatment team. Their needs and challenges should be met as interventions can be effective in improving not only their own health, well-being, and quality of life but also that of those they care for. The aim of this systematic review was to investigate supportive interventions for caregivers of individuals with MS.Methods: We conducted a database search of PubMed, Google Scholar, Science Direct, Scopus, and the Cochrane Library from 2000 to 2021. English-language studies that examined interventions administered directly to caregivers of individuals with MS and evaluated various outcomes were included. The Downs and Black checklist was used to assess the methodological quality of included studies.Results: Twenty of 367 relevant papers fit the eligibility criteria outlined in the methods of this study and were subsequently selected for this review. Of the included studies, there was a notable variance in key characteristics such as methods, outcome measures, sample size, and procedures. Supportive interventions, psychoeducational group interventions, and behavioral-adaptive therapies were the 3 main categories of interventions reviewed; however, each study had a significant correlation between the intervention and outcomes.Conclusions: Despite the small sample size in this study, this review showed that various intervention models that target caregivers of individuals with MS have been successful.","PeriodicalId":14150,"journal":{"name":"International journal of MS care","volume":" ","pages":"266-272"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45192887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Striving to Limit the Impact: Parenting an Adult Child Who Has Multiple Sclerosis-A Grounded Theory Study. 努力限制影响:养育患有多发性硬化症的成年子女-一项有根据的理论研究

International journal of MS care Pub Date : 2023-11-01 Epub Date: 2023-11-08 DOI: 10.7224/1537-2073.2021-053

Camilla Holden, Peter Hewitt, Rachel Tams

{"title":"Striving to Limit the Impact: Parenting an Adult Child Who Has Multiple Sclerosis-A Grounded Theory Study.","authors":"Camilla Holden, Peter Hewitt, Rachel Tams","doi":"10.7224/1537-2073.2021-053","DOIUrl":"10.7224/1537-2073.2021-053","url":null,"abstract":"Background: Multiple sclerosis (MS) is a chronic, progressive autoimmune inflammatory disorder. Its impact is felt not only by individuals but also by their families; however, little is known about the effect on their parents. This study of a cohort from the United Kingdom aimed to develop a conceptual understanding of the parental role and how it changes over time when an adult son or daughter has MS via firsthand accounts.Methods: Twelve parents of adults with MS were recruited from a UK hospital providing outpatient services to people with MS and a branch of a national MS charity. A social constructivist grounded theory approach informed audio-recorded semistructured interviews and subsequent data analysis.Results: In this sample, parents of adults with MS strove to limit the impact of MS on their son or daughter by undertaking practical caring activities and providing emotional support. The developed theoretical model illustrates how, in their efforts to meet this aim, parents experienced competing demands between prioritizing their child's needs and managing the effects on their life, between managing the emotional experience and protecting their child from the burden of their experience, and between an intensified instinct/desire to help while maintaining their child's independence.Conclusions: Findings indicate that parents may be uniquely affected by their adult son or daughter having MS, advocating for their inclusion in research and clinical interventions addressing family adjustment to MS. Further research is needed to ascertain the generalizability of these findings in comparable samples and to determine the impact of sociodemographic and cultural variables on the observed phenomena.","PeriodicalId":14150,"journal":{"name":"International journal of MS care","volume":" ","pages":"259-265"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634593/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47517415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of Calcitonin Gene-Related Peptide Monoclonal Antibodies for the Treatment of Migraines in Individuals With Multiple Sclerosis 使用降钙素基因相关肽单克隆抗体治疗多发性硬化症患者偏头痛

International journal of MS care Pub Date : 2023-10-20 DOI: 10.7224/1537-2073.2023-013

Ashley Mason, Lauren Fragapane, Zuleyma Toledo-Nieves, Natalie Moreo, Angela Aungst, Derrick Robertson, Janice Maldonado

{"title":"Use of Calcitonin Gene-Related Peptide Monoclonal Antibodies for the Treatment of Migraines in Individuals With Multiple Sclerosis","authors":"Ashley Mason, Lauren Fragapane, Zuleyma Toledo-Nieves, Natalie Moreo, Angela Aungst, Derrick Robertson, Janice Maldonado","doi":"10.7224/1537-2073.2023-013","DOIUrl":"https://doi.org/10.7224/1537-2073.2023-013","url":null,"abstract":"Abstract Background: Migraines are a common comorbidity and source of disability in patients with chronic inflammatory diseases like multiple sclerosis (MS). Recently, therapeutic agents for episodic and chronic migraine known as calcitonin gene-related peptide (CGRP) inhibitors have shown to effectively control migraine attacks and improve quality of life in the general population. This study explored the use of these novel agents in individuals with comorbid MS. Methods: This was a retrospective, population-based cohort study at the University of South Florida’s neurology clinic; it evaluated individuals with both MS and migraine. Results: A total of 27 individuals with MS and chronic or episodic migraine who received treatment with a CGRP monoclonal antibody were identified. Of these, 63% reported a reduction in their migraine frequency of greater than 75%. Concurrent use of a disease modifying therapy (DMT) for MS occurred in 82% of patients, and in 37% of these, the DMT used was also a monoclonal antibody. Adverse effects from CGRP monoclonal antibodies were mild and occurred in only 11% of patients, and no patient experienced worsening of their MS symptoms during cotreatment over the duration of the study. Conclusions: Our study showed a significant reduction in migraine frequency and a favorable adverse event profile for individuals with comorbid MS who took CGRP monoclonal antibodies and experienced no worsening of MS symptoms. In individuals with MS, CGRP monoclonal antibodies seem to be a safe and effective therapy for episodic or chronic migraine.","PeriodicalId":14150,"journal":{"name":"International journal of MS care","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135616893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association Between Disease-Modifying Therapy and Information Processing Speed in Multiple Sclerosis 多发性硬化症疾病改善治疗与信息处理速度的关系

International journal of MS care Pub Date : 2023-10-20 DOI: 10.7224/1537-2073.2023-010

Albert Aboseif, Moein Amin, James Bena, Kunio Nakamura, Gabrielle Macaron, Daniel Ontaneda

{"title":"Association Between Disease-Modifying Therapy and Information Processing Speed in Multiple Sclerosis","authors":"Albert Aboseif, Moein Amin, James Bena, Kunio Nakamura, Gabrielle Macaron, Daniel Ontaneda","doi":"10.7224/1537-2073.2023-010","DOIUrl":"https://doi.org/10.7224/1537-2073.2023-010","url":null,"abstract":"Abstract: Background: Cognitive impairment (CI) is common in multiple sclerosis (MS). Processing speed (PS) is often affected, making it an ideal target for monitoring CI. This study aims to evaluate the association between disease-modifying therapy (DMT) use and intensity and longitudinal changes in Processing Speed Test (PST) scores for individuals with MS. Methods: A retrospective analysis of individual PST scores at a single MS center was conducted. Individuals with 2 or more PST assessments were included. Scores on the PST were compared longitudinally between those who had been on a DMT for 2 or more years and those who had been off a DMT for 2 or more years and between those on high-efficacy DMTs and those on low-/moderate-efficacy DMTs. A linear regression model was approximated to evaluate the rate of cognitive change over time. A propensity score adjustment was conducted using a multivariable logistic regression. Results: The cohort was 642 individuals, 539 on DMT and 103 off DMT. Median age and disease duration was 49.7 (interquartile range [IQR] 42.4-57.9) and 16.6 years (IQR 9.3-23.0) in the DMT group, and 58.9 (IQR 52.2-65.3) and 20.0 years (IQR 14.1-31.4) in the non-DMT group. Both cohorts were predominantly female (75% DMT, 79.6% non-DMT), with a mean of 4 assessments (IQR 3-5), and an average monitoring duration of 1.9 years (1.2-2.4) in the DMT group, and 1.8 years (1.4-2.4) in the non-DMT group. After adjusting for multiple factors, DMT status and intensity were not found to be significant predictors of longitudinal PST change. Conclusions: Neither DMT status nor intensity were significant predictors of cognitive processing speed over a period of approximately 2 years. Future prospective multicenter trials are needed to further support these findings.","PeriodicalId":14150,"journal":{"name":"International journal of MS care","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135618177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association Between Improved Serum Fatty Acid Profiles and Cognitive Function During a Dietary Intervention Trial in Relapsing-Remitting Multiple Sclerosis 在一项复发-缓解型多发性硬化症患者饮食干预试验中，血清脂肪酸谱改善与认知功能的关系

International journal of MS care Pub Date : 2023-09-29 DOI: 10.7224/1537-2073.2023-037

Solange M. Saxby, Carlyn Haas, Farnoosh Shemirani, Tyler J. Titcomb, Patrick Ten Eyck, Linda M. Rubenstein, Karin F. Hoth, Linda G. Snetselaar, Terry L. Wahls

{"title":"Association Between Improved Serum Fatty Acid Profiles and Cognitive Function During a Dietary Intervention Trial in Relapsing-Remitting Multiple Sclerosis","authors":"Solange M. Saxby, Carlyn Haas, Farnoosh Shemirani, Tyler J. Titcomb, Patrick Ten Eyck, Linda M. Rubenstein, Karin F. Hoth, Linda G. Snetselaar, Terry L. Wahls","doi":"10.7224/1537-2073.2023-037","DOIUrl":"https://doi.org/10.7224/1537-2073.2023-037","url":null,"abstract":"Abstract Background: Cognitive impairment is a common multiple sclerosis (MS)-related symptom that impacts quality of life (QOL). Diet interventions are shown to be beneficial in managing QOL, and the intake of essential fatty acids is linked with improved cognitive function. However, the effect of diets on serum fatty acid profiles and cognitive function is unknown. Methods: A previous randomized parallel-arm trial recruited participants with relapsing-remitting MS (N = 77). Study visits included 4 time points: run-in, baseline, 12 weeks, and 24 weeks. During the run-in phase, participants followed their usual diet and were then randomly assigned to either a modified paleolithic (Wahls) or a low saturated fat (Swank) diet at baseline. Assessments at study visits included cognitive function assessed by Symbol Digit Modalities Test-Oral (SDMT-O) and Perceived Deficits Questionnaire (PDQ), and serum fatty acids, including eicosapentaenoic (EPA), docosahexaenoic (DHA), and arachidonic (ARA) acids. Results: Both groups had significant improvements in all serum fatty acids (P &lt; .01), except for ARA, as well as SDMT-O at 24-weeks (P &lt; .05), total PDQ at 12- and 24-weeks (P &lt; .01) compared to baseline values. The 12-week changes in omega-3 (EPA + DHA) index and EPA serum fatty acids were associated with SDMT-O changes (P ≤ .05); however, the changes in fatty acid levels did not mediate the effect of the diets on SDMT-O or PDQ (P &gt; .05). Conclusions: Both diets led to improvements in serum fatty acid profiles and cognitive function, with associations between the 12-week omega-3 (EPA + DHA) index and EPA changes with SDMT-O.","PeriodicalId":14150,"journal":{"name":"International journal of MS care","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135132141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Multiple Sclerosis, Fatigue, Expanded Disability Status Scale: A Cross-Sectional Exploration of Sleep Efficiency and Quantitative Sleep Parameters 多发性硬化症，疲劳，扩展残疾状态量表:睡眠效率和定量睡眠参数的横断面探索

International journal of MS care Pub Date : 2023-09-15 DOI: 10.7224/1537-2073.2022-118

Munther Queisi, Hrayr Attarian, Victoria P. Cipriani, Saria Azzi, Olivia Kaczmarek, Barbara Bumstead, Marijean Buhse, Myassar Zarif, Daniel Golan, Jeffrey Wilken, Thomas Covey, Mark Gudesblatt

{"title":"Multiple Sclerosis, Fatigue, Expanded Disability Status Scale: A Cross-Sectional Exploration of Sleep Efficiency and Quantitative Sleep Parameters","authors":"Munther Queisi, Hrayr Attarian, Victoria P. Cipriani, Saria Azzi, Olivia Kaczmarek, Barbara Bumstead, Marijean Buhse, Myassar Zarif, Daniel Golan, Jeffrey Wilken, Thomas Covey, Mark Gudesblatt","doi":"10.7224/1537-2073.2022-118","DOIUrl":"https://doi.org/10.7224/1537-2073.2022-118","url":null,"abstract":"Abstract Background Poor sleep quality and sleep disorders are more prevalent in individuals with multiple sclerosis (MS) than in the general population. Poor sleep has been correlated with worse MS outcomes. Sleep efficiency (SE) is one of the most sensitive markers of sleep quality. There is very little written about SE and other polysomnography (PSG) parameters and MS measures. Methods This is a retrospective review of 280 consecutive individuals with MS evaluated by PSGs and other standardized MS measures over 13 years at a comprehensive MS center. In addition, the cohort was assessed with 2 fatigue scales, the Epworth Sleepiness Scale, and the Expanded Disability Status Scale. A comparison of means test (independent t test) and r, or correlation coefficient, were used. Results The PSG measures of SE and Total Sleep Time were significantly different between a group of individuals with MS with a disease duration of more than 5 years vs a group of individuals with MS with a disease duration less then or equal to 5 years. Prevalence of obstructive sleep apnea was 63%, higher than reported in the literature while the prevalence of moderate to severe obstructive sleep apnea was 33.4%, which was lower than reported. Conclusions Longer disease duration as well as worse disability correlate with sleep quality as measured by SE.","PeriodicalId":14150,"journal":{"name":"International journal of MS care","volume":"169 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135436956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validated, Quantitative, Machine Learning-Generated Neurologic Assessment of Multiple Sclerosis Using a Mobile Application 使用移动应用程序验证，定量，机器学习生成的多发性硬化症神经系统评估

International journal of MS care Pub Date : 2023-09-12 DOI: 10.7224/1537-2073.2023-009

Sharon Stoll, Charisse Litchman, Noah Rubin, Larry Rubin, Timothy Vartanian

{"title":"Validated, Quantitative, Machine Learning-Generated Neurologic Assessment of Multiple Sclerosis Using a Mobile Application","authors":"Sharon Stoll, Charisse Litchman, Noah Rubin, Larry Rubin, Timothy Vartanian","doi":"10.7224/1537-2073.2023-009","DOIUrl":"https://doi.org/10.7224/1537-2073.2023-009","url":null,"abstract":"Abstract Background: The BeCare MS Link mobile app collects data as users complete different in-app assessments. It was specifically developed to evaluate the symptomatology and neurologic function of patients with multiple sclerosis (MS) and to become a digital equivalent of the Expanded Disability Status Scale (EDSS) and other standard clinical metrics of MS progression. Methods: Our research compared EDSS scores derived from the BeCare MS link app to EDSS scores derived from neurologist assessment for the same cohort of 35 patients diagnosed with MS. App-derived data was supplied to 4 different machine learning algorithms (MLAs) with an independent EDSS score prediction generated from each. These scores were compared to the clinically-derived EDSS score to assess the similarity of the scores and to determine an accuracy estimate for each MLA. The trial is registered on ClinicalTrials.gov as NCT04281160. Results: Out of the 4 MLAs employed, the most accurate MLA produced 19 EDSS score predictions that exactly matched the clinically-derived scores, 21 score predictions within 0.5 EDSS points, and 32 score predictions within 1 EDSS point. The remaining MLAs also provided a relatively high level of accuracy in predicting EDSS scores when compared to clinically-derived EDSS, with over 80% of scores predicted within 1 point and a mean squared error with a range of 1.05 to 1.37. Conclusions: The BeCare MS Link app can replicate the clinically-derived EDSS assessment of a patient with MS. The app may also offer a more complete evaluation of disability in patients with MS.","PeriodicalId":14150,"journal":{"name":"International journal of MS care","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135877989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Foot Reflexology on Patients With Multiple Sclerosis: A Systematic Review of Current Evidence 足部反射疗法对多发性硬化症患者的影响:当前证据的系统回顾

International journal of MS care Pub Date : 2023-09-12 DOI: 10.7224/1537-2073.2022-093

Boopalan Deenadayalan, Vijayakumar Venugopal, Ravi Poornima, Vanamoorthy Mahesh Kannan, Anandhan Akila, Chidambaram Yogapriya, Kuppusamy Maheshkumar

{"title":"Effect of Foot Reflexology on Patients With Multiple Sclerosis: A Systematic Review of Current Evidence","authors":"Boopalan Deenadayalan, Vijayakumar Venugopal, Ravi Poornima, Vanamoorthy Mahesh Kannan, Anandhan Akila, Chidambaram Yogapriya, Kuppusamy Maheshkumar","doi":"10.7224/1537-2073.2022-093","DOIUrl":"https://doi.org/10.7224/1537-2073.2022-093","url":null,"abstract":"Abstract Background: Individuals with multiple sclerosis (MS) commonly experience fatigue, discomfort, sleep problems, anxiety, and reduced quality of life. Studies have shown that foot reflexology can help relieve these symptoms. The objective of this current study is to systematically review the effects of foot reflexology on patients with MS. Methods: We conducted a systematic review of published literature in many databases, including PubMed, EMBASE, and Cochrane Library, from January 1, 2000, to January 27, 2022. With language restrictions, we included randomized controlled trials of foot reflexology interventions for MS that had any clinical or psychological symptom measurements as outcomes. The Cochrane risk-of-bias tool was used to assess evidence quality. Two authors independently screened titles and abstracts. Potential eligible articles were retrieved for full-text review. A third author checked for excluded records. All discrepancies were resolved through a discussion among the 4 reviewing authors. Results: A total of 154 studies were identified; 9 studies with 545 MS patients were included in this review. The most frequently reported findings of foot reflexology intervention in individuals with MS were reductions in fatigue, pain, muscle spasms, stiffness, and psychological symptoms and improvement in bowel and bladder functions and quality of life Conclusions: The findings suggest that foot reflexology could be a safe and effective modality to reduce the physical, and psychological symptoms and also improve the quality of life for individuals with MS; however, well-designed, large-scale trials are required to confirm the effect.","PeriodicalId":14150,"journal":{"name":"International journal of MS care","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135877987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1