Disease Models & Mechanisms最新文献

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First person – Saba Naghipour 第一人称,Saba Naghipour
Disease Models & Mechanisms Pub Date : 2023-05-01 DOI: 10.1242/dmm.050247
{"title":"First person – Saba Naghipour","authors":"","doi":"10.1242/dmm.050247","DOIUrl":"https://doi.org/10.1242/dmm.050247","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Saba Naghipour is first author on ‘ A gut microbiome metabolite paradoxically depresses contractile function while activating mitochondrial respiration’, published in DMM. Saba is a PhD candidate in the lab of Eugene Du Toit at Griffith University, Southport, Australia, investigating the role of trimethylamine-N-oxide in the development of cardiovascular disease.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115759394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modifying the approach to cardiomyopathy research 修改心肌病研究方法
Disease Models & Mechanisms Pub Date : 2023-05-01 DOI: 10.1242/dmm.050310
Kirsty M Hooper
{"title":"Modifying the approach to cardiomyopathy research","authors":"Kirsty M Hooper","doi":"10.1242/dmm.050310","DOIUrl":"https://doi.org/10.1242/dmm.050310","url":null,"abstract":"","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126922602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First person – Mark Hanson 第一人称——马克·汉森
Disease Models & Mechanisms Pub Date : 2023-04-01 DOI: 10.1242/dmm.050153
{"title":"First person – Mark Hanson","authors":"","doi":"10.1242/dmm.050153","DOIUrl":"https://doi.org/10.1242/dmm.050153","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Mark Hanson is first author on ‘ Antimicrobial peptides do not directly contribute to aging in Drosophila, but improve lifespan by preventing dysbiosis’, published in DMM. Mark conducted the research described in this article while working as a postdoctoral researcher in Prof. Bruno Lemaitre's lab at École Polytechnique Fédérale de Lausanne (EPFL), Switzerland. He is now a Research Fellow in the lab of Prof. Ben Longdon at University of Exeter, Penryn, UK, investigating the evolution of immune systems to learn how our body's defences are adapted to the world around them.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"1 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134466116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First person – Toni Lemmetyinen 第一人称,Toni Lemmetyinen
Disease Models & Mechanisms Pub Date : 2023-04-01 DOI: 10.1242/dmm.050195
{"title":"First person – Toni Lemmetyinen","authors":"","doi":"10.1242/dmm.050195","DOIUrl":"https://doi.org/10.1242/dmm.050195","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Toni Lemmetyinen is first author on ‘ Fibroblast-derived EGF ligand neuregulin 1 induces fetal-like reprogramming of the intestinal epithelium without supporting tumorigenic growth’, published in DMM. Toni is a PhD student in the lab of Saara Ollila at the University of Helsinki, investigating how stromal fibroblasts regulate the intestinal epithelium.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123562319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First person – Brittany Truong 第一人称,布列塔尼·张
Disease Models & Mechanisms Pub Date : 2023-04-01 DOI: 10.1242/dmm.050192
{"title":"First person – Brittany Truong","authors":"","doi":"10.1242/dmm.050192","DOIUrl":"https://doi.org/10.1242/dmm.050192","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Brittany Truong is first author on ‘ PRDM1 DNA-binding zinc finger domain is required for normal limb development and is disrupted in split hand/foot malformation’, published in DMM. Brittany is a PhD Student in the lab of Kristin B. Artinger at the University of Colorado Anschutz Medical Campus, Aurora, CO, USA, investigating the molecular and genetic mechanisms involved in the development of the limb.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125531111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
To the fin and back again: expanding our understanding of congenital limb malformation 到鳍再回来:扩大我们对先天性肢体畸形的认识
Disease Models & Mechanisms Pub Date : 2023-04-01 DOI: 10.1242/dmm.050230
M. Harris
{"title":"To the fin and back again: expanding our understanding of congenital limb malformation","authors":"M. Harris","doi":"10.1242/dmm.050230","DOIUrl":"https://doi.org/10.1242/dmm.050230","url":null,"abstract":"","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124427005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First person – Rebeka Popovic and Yizhou Yu 第一人称——丽贝卡·波波维奇和俞一舟
Disease Models & Mechanisms Pub Date : 2023-04-01 DOI: 10.1242/dmm.050220
{"title":"First person – Rebeka Popovic and Yizhou Yu","authors":"","doi":"10.1242/dmm.050220","DOIUrl":"https://doi.org/10.1242/dmm.050220","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Rebeka Popovic and Yizhou Yu are co-first authors on ‘ Upregulation of Tribbles decreases body weight and increases sleep duration’, published in DMM. Rebeka conducted the research described in this article while a PhD student in Dr Luis Miguel Martins’ lab at the University of Cambridge, Cambridge, UK. Her PhD investigated mechanisms of neurodegeneration, with a focus on endoplasmic reticulum stress and mitochondrial dysfunction, as well as inter-organ communication in disease. She is now a postdoc in the lab of Prof. Fiona Ducotterd at the Drug Discovery Institute at University College London, London, UK, exploring new therapeutic targets for the treatment of neurodegenerative diseases. Yizhou is a PhD student in the lab of Dr Luis Miguel Martins at the University of Cambridge, Cambridge, UK. His research involves combining computational biology and wet-lab techniques to understand the genetic and environmental causes of age-related diseases.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133863046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Living on the edge: how stromal cells restrict liver cancer invasion 生活在边缘:基质细胞如何限制肝癌的侵袭
Disease Models & Mechanisms Pub Date : 2023-03-01 DOI: 10.1242/dmm.050166
L. Boulter
{"title":"Living on the edge: how stromal cells restrict liver cancer invasion","authors":"L. Boulter","doi":"10.1242/dmm.050166","DOIUrl":"https://doi.org/10.1242/dmm.050166","url":null,"abstract":"","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127161115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First person – John (Eddie) Edmund La Marca 第一人称-约翰(埃迪)埃德蒙·拉·马卡
Disease Models & Mechanisms Pub Date : 2023-03-01 DOI: 10.1242/dmm.050179
{"title":"First person – John (Eddie) Edmund La Marca","authors":"","doi":"10.1242/dmm.050179","DOIUrl":"https://doi.org/10.1242/dmm.050179","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. John La Marca is first author on ‘ A Drosophila chemical screen reveals synergistic effect of MEK and DGKa inhibition in Ras-driven cancer’, published in DMM. John conducted the research described in this article while a research officer in Helena Richardson's lab at La Trobe University, Bundoora, Australia. He is now a research officer in the lab of Gemma Kelly and Marco Herold at the Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia, investigating genetics, cancer and molecular signalling.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"58 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123460020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First person – Xuming Zhu 第一人称:朱旭明
Disease Models & Mechanisms Pub Date : 2023-03-01 DOI: 10.1242/dmm.050160
{"title":"First person – Xuming Zhu","authors":"","doi":"10.1242/dmm.050160","DOIUrl":"https://doi.org/10.1242/dmm.050160","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Xuming Zhu is first author on ‘ FZD2 regulates limb development by mediating β-catenin-dependent and -independent Wnt signaling pathways’, published in DMM. Xuming is an instructor in the lab of Sarah E. Millar at Icahn School of Medicine at Mount Sinai, New York, NY, USA, investigating the molecular mechanisms that underlie the development of appendages, epithelial homeostasis and diseases.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132686746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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