{"title":"First person – Patricia Dranchak","authors":"","doi":"10.1242/dmm.050157","DOIUrl":"https://doi.org/10.1242/dmm.050157","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Patricia Dranchak is first author on ‘ In vivo quantitative high-throughput screening for drug discovery and comparative toxicology’, published in DMM. She is a staff scientist in the lab of James Inglese at the National Center for Advancing Translational Sciences (NCATS), Rockville, MD, USA. Patricia is interested in developing and integrating novel strategies and model systems to identify chemical modulators targeting the molecular bases of rare and neglected disease pathophysiologies.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125548472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"First person – Derek Reznik","authors":"","doi":"10.1242/dmm.050097","DOIUrl":"https://doi.org/10.1242/dmm.050097","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Derek Reznik is first author on ‘ Magel2 truncation alters select behavioral and physiological outcomes in a rat model of Schaaf-Yang syndrome’, published in DMM. Derek is a PhD student in the lab of Rodney Samaco at Baylor College of Medicine, Houston, TX, USA, investigating the underlying mechanisms of rare neurodevelopmental disorders using novel model systems to bring actionable therapies to patients.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126599236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"First person – Ateequllah Hayat","authors":"","doi":"10.1242/dmm.050100","DOIUrl":"https://doi.org/10.1242/dmm.050100","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Ateequllah Hayat is first author on ‘ Low HER2 expression in normal breast epithelium enables dedifferentiation and malignant transformation via chromatin opening’, published in DMM. Ateequllah conducted the research described in this article while a PhD student in Gabriella Ficz's lab at Queen Mary University of London, London, UK, and is now a lecturer in drug development at St George's, University of London, London, UK, investigating transcriptomic/epigenomic changes in cancer resistance.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116524750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"First person – Lídia Faria","authors":"","doi":"10.1242/dmm.050106","DOIUrl":"https://doi.org/10.1242/dmm.050106","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Lídia Faria is first author on ‘ Activation of an actin signalling pathway in pre-malignant mammary epithelial cells by P-cadherin is essential for transformation’, published in DMM. Lídia is a PhD student in the lab of Florence Janody at Universidade do Porto, Porto, Portugal, investigating how pre-malignant cells acquire characteristics of tumour cells.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127311047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New drugs to squash the spread of malaria","authors":"Kirsty M Hooper","doi":"10.1242/dmm.050096","DOIUrl":"https://doi.org/10.1242/dmm.050096","url":null,"abstract":"","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130583086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"First person – Sabrina Yahiya","authors":"","doi":"10.1242/dmm.050069","DOIUrl":"https://doi.org/10.1242/dmm.050069","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Sabrina Yahiya is first author on ‘ A novel class of sulphonamides potently block malaria transmission by targeting a Plasmodium vacuole membrane protein’, published in DMM. Sabrina conducted the research described in this article while a PhD candidate in Prof. Jake Baum's lab at Imperial College London, UK. She is now a scientist in the Infectious Diseases & Vaccines Group at Kymab, a Sanofi company, in Cambridge, UK, and is interested in the development of therapeutics targeting infectious diseases, with a focus on blocking malaria transmission.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"108 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117254077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Let's talk about sex… obesity and melanoma","authors":"Kirsty M Hooper","doi":"10.1242/dmm.050084","DOIUrl":"https://doi.org/10.1242/dmm.050084","url":null,"abstract":"","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133434432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"First person – Pinaki Mondal and Neesha Patel","authors":"","doi":"10.1242/dmm.050070","DOIUrl":"https://doi.org/10.1242/dmm.050070","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Pinaki Mondal and Neesha Patel are co-first authors on ‘ Induction of pancreatic neoplasia in the KRAS/TP53 Oncopig’, published in DMM. Pinaki is a research scientist, and Neesha is a surgical resident, in the lab of Mark A. Carlson at University of Nebraska Medical Center, Omaha, NE, USA, investigating pancreatic adenocarcinoma and reprograming of its complex microenvironment in therapy resistance.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"328 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122043455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"First person – Marco Travaglio","authors":"","doi":"10.1242/dmm.050030","DOIUrl":"https://doi.org/10.1242/dmm.050030","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Marco Travaglio is first author on ‘ Increased cysteine metabolism in PINK1 models of Parkinson's disease’, published in DMM. Marco is a PhD student at the University of Cambridge in the lab of Luis Miguel Martins at the MRC Toxicology Unit in Cambridge (UK), and interested in developing novel therapeutic targets for Parkinson's disease.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"94 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122307856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"First person – Zhang Li","authors":"","doi":"10.1242/dmm.050040","DOIUrl":"https://doi.org/10.1242/dmm.050040","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Zhang Li is first author on ‘ A kidney resident macrophage subset is a candidate biomarker for renal cystic disease in preclinical models’, published in DMM. Zhang is a postdoc in the lab of Bradley Yoder at University of Alabama at Birmingham, Birmingham, AL, USA, investigating the roles of renal macrophages and kidney injury in the pathology of cystic kidney diseases.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127491286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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