Disease Models & Mechanisms最新文献

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First person – Anaïs Kervadec and James Kezos 第一人称 - 安娜-凯尔瓦达克和詹姆斯-凯佐斯
Disease Models & Mechanisms Pub Date : 2023-07-01 DOI: 10.1242/dmm.050355
{"title":"First person – Anaïs Kervadec and James Kezos","authors":"","doi":"10.1242/dmm.050355","DOIUrl":"https://doi.org/10.1242/dmm.050355","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Anaïs Kervadec and James Kezos are co-first authors on ‘ Multiplatform modeling of atrial fibrillation identifies phospholamban as a central regulator of cardiac rhythm’, published in DMM. Anaïs conducted the research described in this article while a postdoctoral associate in Alexandre Colas' lab at Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA, and is now a scientist at Avidity Biosciences, La Jolla, CA, USA, utilising cutting-edge scientific approaches to discover molecular mechanisms of action, with the ultimate goal of developing novel therapies for patients in need. James is a postdoctoral fellow in the lab of Karen Ocorr at Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA, utilising multimodel system approaches to investigate genetic, molecular and physiological mechanisms underlying cardiac development and disease.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134154629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First person – Kevin Zhang 第一人称——张凯文
Disease Models & Mechanisms Pub Date : 2023-07-01 DOI: 10.1242/dmm.050389
{"title":"First person – Kevin Zhang","authors":"","doi":"10.1242/dmm.050389","DOIUrl":"https://doi.org/10.1242/dmm.050389","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Kevin Zhang is first author on ‘ Oxidative stress induces lysosomal membrane permeabilization and ceramide accumulation in retinal pigment epithelial cells’, published in DMM. Kevin is an MD/PhD student in the lab of Dr Joshua Dunaief at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA, investigating the cell biology and metabolism of the eye.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"122 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127507515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unsheathing new insights into lysosomal storage disorders 揭示溶酶体贮积障碍的新见解
Disease Models & Mechanisms Pub Date : 2023-06-27 DOI: 10.1242/dmm.050364
Kirsty M Hooper
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引用次数: 0
First person – Valentina Zuco 第一人称,瓦伦蒂娜·祖科
Disease Models & Mechanisms Pub Date : 2023-06-01 DOI: 10.1242/dmm.050313
{"title":"First person – Valentina Zuco","authors":"","doi":"10.1242/dmm.050313","DOIUrl":"https://doi.org/10.1242/dmm.050313","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Valentina Zuco is first author on ‘ Effects of irinotecan plus trabectedin on a desmoplastic small round cell tumor patient-derived xenograft’, published in DMM. Valentina is a scientist in the lab of Nadia Zaffaroni at Fondazione IRCCS Istituto Tumori, Milan, Italy, investigating patient-derived tumor models to identify new therapeutic strategies for patients with rare cancers to be translated into clinical trials.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122907629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First person – Sara Bonzano 第一人称- Sara Bonzano
Disease Models & Mechanisms Pub Date : 2023-06-01 DOI: 10.1242/dmm.050335
{"title":"First person – Sara Bonzano","authors":"","doi":"10.1242/dmm.050335","DOIUrl":"https://doi.org/10.1242/dmm.050335","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Sara Bonzano is first author on ‘ NR2F1 shapes mitochondria in the mouse brain, providing new insights into Bosch-Boonstra-Schaaf optic atrophy syndrome’, published in DMM. Sara is a postdoc in the lab of Silvia De Marchis at the University of Turin, Turin, Italy, investigating the cellular and molecular mechanisms by which NR2F1 regulates postnatal brain plasticity.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125247425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Getting to the cortex of sexual dimorphism 进入两性异形的大脑皮层
Disease Models & Mechanisms Pub Date : 2023-06-01 DOI: 10.1242/dmm.050370
Kirsty M Hooper
{"title":"Getting to the cortex of sexual dimorphism","authors":"Kirsty M Hooper","doi":"10.1242/dmm.050370","DOIUrl":"https://doi.org/10.1242/dmm.050370","url":null,"abstract":"","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116548604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First person – Lorena Maili
Disease Models & Mechanisms Pub Date : 2023-06-01 DOI: 10.1242/dmm.050302
{"title":"First person – Lorena Maili","authors":"","doi":"10.1242/dmm.050302","DOIUrl":"https://doi.org/10.1242/dmm.050302","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Lorena Maili is first author on ‘ Facial analytics based on a coordinate extrapolation system (zFACE) for morphometric phenotyping of developing zebrafish’, published in DMM. Lorena conduced the research described in the article while a graduate research assistant (predoctoral student) in the lab of Dr Jacqueline Hecht (in collaboration with Dr George Eisenhoffer) at The University of Texas MD Anderson Cancer Center, Houston, TX, USA. She is now a postdoctoral fellow in the lab of Dr Paul Trainor at Stowers Institute for Medical Research, Kansas City, MO, USA, investigating genetic regulation of craniofacial development.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"105 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124055987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First person – Rodanthi Lyraki 第一人称- Rodanthi Lyraki
Disease Models & Mechanisms Pub Date : 2023-05-10 DOI: 10.1242/dmm.050246
{"title":"First person – Rodanthi Lyraki","authors":"","doi":"10.1242/dmm.050246","DOIUrl":"https://doi.org/10.1242/dmm.050246","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Rodanthi Lyraki is first author on ‘ Crosstalk between androgen receptor and WNT/β-catenin signaling causes sex-specific adrenocortical hyperplasia in mice’, published in DMM. Rodanthi conducted the research described in this article while a postdoctoral Fellow in Andreas Schedl's lab at Université Côte d’Azur, Nice, France.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129677623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First person – Arthur Lensen and Margarida C. Gomes 第一人称:阿瑟·伦森和玛格丽达·c·戈麦斯
Disease Models & Mechanisms Pub Date : 2023-05-10 DOI: 10.1242/dmm.050255
{"title":"First person – Arthur Lensen and Margarida C. Gomes","authors":"","doi":"10.1242/dmm.050255","DOIUrl":"https://doi.org/10.1242/dmm.050255","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Arthur Lensen and Margarida C. Gomes are co-first authors on ‘ An automated microscopy workflow to study Shigella–neutrophil interactions and antibiotic efficacy in vivo’, published in DMM. Arthur conducted the research described in this article while an MSc student in Serge Mostowy's lab at the London School of Hygiene and Tropical Medicine, UK. He is now a PhD student in the lab of Jost Enninga at Institut Pasteur, Paris, France, investigating host-pathogen interactions at the cellular and molecular level. Margarida is a research fellow in Serge Mostowy's lab at the London School of Hygiene and Tropical Medicine, UK, and works with the zebrafish infection model to study host-pathogen interactions, focusing on trained innate immunity.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"231 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122774546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First person – Ariany Oliveira-Santos
Disease Models & Mechanisms Pub Date : 2023-05-10 DOI: 10.1242/dmm.050221
{"title":"First person – Ariany Oliveira-Santos","authors":"","doi":"10.1242/dmm.050221","DOIUrl":"https://doi.org/10.1242/dmm.050221","url":null,"abstract":"\u0000 First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Ariany Oliveira-Santos is first author on ‘ Vemurafenib improves muscle histopathology in a mouse model of LAMA2-related congenital muscular dystrophy’, published in DMM. Ariany is a postdoctoral researcher in the lab of Dean Burkin at the University of Nevada, Reno, USA, investigating muscle biology and the development of new therapeutics for muscle diseases, particularly muscular dystrophies.","PeriodicalId":141347,"journal":{"name":"Disease Models & Mechanisms","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114362814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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