Nur Naqibah Lokhman, Zailina Hashim, Juliana Jalaludin, Ho Yu Bin, Vivien How, Nur Adibah Mohidem
{"title":"Levels of acetylcholinesterase and DNA damage in children exposed to organophosphate pesticides in Tanjung Karang, Selangor, Malaysia.","authors":"Nur Naqibah Lokhman, Zailina Hashim, Juliana Jalaludin, Ho Yu Bin, Vivien How, Nur Adibah Mohidem","doi":"10.1080/09603123.2025.2492367","DOIUrl":"https://doi.org/10.1080/09603123.2025.2492367","url":null,"abstract":"<p><p>This study aims to determine the levels of acetylcholinesterase in blood and DNA damage in children exposed to organophosphate pesticides in Tanjung Karang, Selangor, Malaysia. The acetylcholinesterase level was analysed using a Cholinesterase Test Kit. A comet assay was applied on the cheek wall, where DNA was liberated from the head of the comet assay. There was a significant difference in the acetylcholinesterase levels (<i>p</i> = <0.001) between the exposed and control groups. There was also a significant correlation between acetylcholinesterase levels and the length of the comet tail in the exposed group (<i>p</i> = 0.028) and in the combined groups (<i>p</i> < 0.001). The distance from the children's houses to the paddy field ranged from less than 100 m to more than 1,000 m, and acetylcholinesterase levels showed a significant relationship with micronucleus frequency and comet assay. Cycling showed a significant relationship with the micronucleus frequency. A distance of less than 100 m from home to school, completion of primary school, and having a father who worked as a farmer were significantly associated with the comet assay. The children exposed to organophosphate pesticides exhibit lower levels of acetylcholinesterase and an increase in comet tail length, indicating heightened DNA damage.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"1-12"},"PeriodicalIF":2.2,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enhancing grape maturation and antioxidant profiles in <i>Red Globe</i> grapes (<i>Vitis vinifera</i>) using nanoemulsion of <i>Tetraclinis articulata</i> essential oil.","authors":"Safa Rguez, Ghassen Abid, Naceur Djébali, Iness Bettaieb Rebey, Rym Essid, Majdi Hammami, Kamel Hessini, Kamel Msaada, Ibtissem Hamrouni","doi":"10.1080/09603123.2025.2492370","DOIUrl":"https://doi.org/10.1080/09603123.2025.2492370","url":null,"abstract":"<p><p>The growing demand for eco-friendly agricultural solutions has led to increased interest in plant-based biostimulants. This study evaluates the potential of a nanoemulsion of <i>Tetraclinis articulata</i> essential oil (NANO-TA) as a natural elicitor to enhance the technological and phenolic maturity of Red Globe grapes in an organic cultivation system. Vine plants were treated with NANO-TA, formulated from an essential oil rich in α-pinene (17.43%) and bornyl acetate (22.29%). Treated grapes showed faster maturation, with an increased pH (3.96 vs. 3.87), higher soluble solids (16.54 vs. 15.32°Brix), and improved maturity index (17.98 vs. 16.13), alongside reduced titratable acidity (10.40 g/L vs. 12.18 g/L). Enhanced berry coloration (CIRG 4.18 vs. 3.67) further confirmed its effect on fruit ripening. In early veraison, treated grapes exhibited higher polyphenol levels and antioxidant activity. However, at full maturity, untreated grapes accumulated more polyphenols and flavonoids (2.33 mg GAE/mL and 3.08 mg QE/mL vs. 1.22 mg GAE/mL and 2.3 mg QE/mL) and showed greater antioxidant activity (61.18% vs. 51.55% DPPH inhibition), likely due to a dilution effect in larger berries. These findings suggest that NANO-TA accelerates grape maturation naturally and enhances key quality indicators, positioning it as a sustainable alternative to synthetic agrochemicals in organic viticulture.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"1-13"},"PeriodicalIF":2.2,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of the relationship between intuitive eating, mindful eating, body weight, and eating disorders: path analysis research on future health professionals.","authors":"Çağdaş Salih Meriç, Nurcan Yabanci Ayhan","doi":"10.1080/09603123.2025.2492362","DOIUrl":"https://doi.org/10.1080/09603123.2025.2492362","url":null,"abstract":"<p><p>Intuitive and mindful eating are included in the current literature as two adaptable, current, and positive eating styles. This descriptive-cross-sectional study included 689 university students. The questionnaire form consists of the nutritional habits and anthropometric measurements of university students, \"Mindful Eating Questionnaire (MEQ)\", \"Intuitive Eating Scale-2 (IES-2)\", \"Eating Attitudes Test-Short Form (EAT-26)\", and the \"International Physical Activity Questionnaire-Short Form (IPAQ-SF)\". About 70.4% of participants with a mean age of 19.76 ± 1.32 years were classified as \"normal\" according to BMI; the mean BMI was 21.9 ± 3.2 kg/m<sup>2</sup>. IES-2 and MEQ scores of overweight/obese students are lower than those of underweight and normal-weight students (<i>p</i> < 0.01). A strong negative correlation exists between BMI, MEQ (<i>r</i> = -.134), IES-2 (<i>r</i> = -.353), and IPAQ-SF (<i>r</i> = -.127), and a strong positive correlation with EAT-26 (<i>r</i> = .209; <i>p</i> < 0.01). Standardized coefficients in the path model between IES and BMI (β= -0.314, <i>R</i> = -.167, <i>p</i> < 0.01), EAT (β= -0.221, <i>R</i> = -3.32, <i>p</i> < 0.01), MEQ (β = 0.304, <i>R</i> = 0.188, <i>p</i> < 0.01) indicate that intuitive eating significantly affects the BMI, eating attitudes, and mindful eating. Intuitive eating and mindful eating may be a promising, holistic, and long-term treatment approach for future health professionals by integrating traditional body weight management strategies.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"1-10"},"PeriodicalIF":2.2,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Valorisation of hydrodistillation by-products from Damask Rose (<i>Rosa damascena</i>): extraction, characterization, and bioactivity of phenolic compounds with biological properties.","authors":"Walid Yeddes, Safa Reguez, Iness Betaieb Rebey, Wissem Aidi Wannes, Hammami Majdi, Sarra Dakhlaoui, Selmi Sawsen, Kamel Msaada, Moufida Saidani Tounsi","doi":"10.1080/09603123.2025.2491634","DOIUrl":"https://doi.org/10.1080/09603123.2025.2491634","url":null,"abstract":"<p><p>The present study focuses on the valorization of aqueous waste generated from the essential oil distillation of Damask rose (<i>Rosa damascena</i>) petals through the extraction and characterization of their bioactive compounds having potential antioxidant and anti-inflammatory properties. The aqueous waste, referred to as rose water, was subjected to liquid-liquid extraction using ethyl acetate, followed by solvent evaporation and methanol solubilization. The final extract shows a significant bioactivity, with a total phenolic content of 255.45 µg GAE/g dry extract (DE) and a total flavonoid content of 320.86 µg QE/g DE. The antioxidant capacity, assessed via the DPPH radical scavenging assay, revealed an IC<sub>50</sub> value of 18.23 µg/mL, indicating potent activity. HPLC-DAD analysis identified key phenolic compounds, including protocatechuic acid, gallic acid, syringic acid, ferulic acid, isorhamnetin-3-<i>O</i>-glucoside, quercetin-3-<i>O</i>-rutinoside, ellagic acid, and quercetin. The extract also exhibited dose-dependent anti-inflammatory effects, as evidenced by the inhibition of nitric oxide production in LPS-stimulated RAW 264.7 macrophage cells. The valorization of rose water not only contributes to the discovery of bioactive compounds but also promotes the sustainable management of distillation by-products, reducing waste and minimizing environmental impact.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"1-9"},"PeriodicalIF":2.2,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Phthalate exposure in primary school children: concentrations, oral intake, and risk assessment in Jinan, China.","authors":"Zhiyu Jiang, Lixin Wang, Haoming Yang, Meinan Qu","doi":"10.1080/09603123.2025.2493305","DOIUrl":"https://doi.org/10.1080/09603123.2025.2493305","url":null,"abstract":"<p><p>Phthalates in indoor environments can enter the human body through non-dietary exposure routes. Excessive exposure to phthalates in children may cause health issues. We examined exposure concentrations, oral intake, and risks for primary-school students in their living environments (home, classroom, and outdoor) in Jinan. We collected 138 dust samples and focused on 13 common phthalates. Phthalates were ubiquitous across all environments, with di(2-ethylhexyl) phthalate (DEHP), di-n-butyl phthalate (DnBP), and di-iso-butyl phthalate (DiBP) representing the highest proportions. Concentrations varied by environment: girls' bedrooms > boys' bedrooms, girls' living rooms > boys' living rooms, homes > classrooms > outdoors, and urban outdoors > suburban outdoors. Factors such as PM<sub>2.5</sub> levels, the use of personal care products, item types, and fabric types influenced indoor phthalate concentrations. Oral exposure data showed that the home is the primary exposure environment, accounting for 51%-88%, followed by the classroom and outdoor environments. The carcinogenic risk associated with DEHP exceeded acceptable limits for all children, with four children exhibiting hazard index values greater than 1. We provide significant data on phthalate exposure in primary school children and suggest that exposure reduction strategies should focus on DEHP, DnBP, and DiBP in both homes and classrooms.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"1-19"},"PeriodicalIF":2.2,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of preconception <i>SOD2</i> gene variants and air pollution on gestational length: evidence from a mother-baby cohort.","authors":"Yalong Wang, Junxi Zhang, Jingjing Wu, Panpan Sun, Xi Yan, Cuiping Wu, Wenyi Liu, Na Li, Jing Jin, Fangfang Yu, Yue Ba, Jian Chai, Guoyu Zhou","doi":"10.1080/09603123.2025.2492368","DOIUrl":"https://doi.org/10.1080/09603123.2025.2492368","url":null,"abstract":"<p><p>To explore the relationship between air pollution, preconception <i>SOD2</i> gene variations, and gestational length. A study was conducted on 1,846 mother-baby pairs in Henan Province. Air pollutant was gathered from environmental monitoring stations. Peripheral blood was collected from pregnant women before pregnancy and genotyped to minimize the interference of prenatal air pollution on <i>SOD2</i> gene variations. Multivariable linear regression models were used to analyze the relationship between air pollution and gestational length, with an interaction term (SNP × air pollutant) included to explore the gene-environment interactions. After adjusting for covariates, it was found that exposure to carbon monoxide (CO), sulfur dioxide (SO<sub>2</sub>), ozone (O<sub>3</sub>), fine particulate matter (PM<sub>2.5</sub>), and inhalable particulate matter (PM<sub>10</sub>) was associated with decreased gestational length, while nitrogen dioxide (NO<sub>2</sub>) exposure was associated with increased gestational length (<i>p</i> < 0.05). Furthermore, mothers carrying the A allele of <i>SOD2</i> rs4880 had an increment of 0.17 weeks in gestational length compared to those carrying the G allele (<i>p</i> < 0.05). Interactions on gestational length between <i>SOD2</i> gene polymorphisms (rs4880, rs5746136, and rs2758352) and exposure to CO, NO<sub>2</sub>, SO<sub>2</sub>, PM<sub>2.5</sub>, and PM<sub>10</sub> were observed. These findings suggest that <i>SOD2</i> gene variations may influence the association between prenatal air pollution and gestational length.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"1-11"},"PeriodicalIF":2.2,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143965665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quantification of health risk due to poor sanitation infrastructure in slums of urban Khulna, Bangladesh.","authors":"S M Tafsirul Islam, Md Ahsanul Kabir","doi":"10.1080/09603123.2025.2489128","DOIUrl":"https://doi.org/10.1080/09603123.2025.2489128","url":null,"abstract":"<p><p>Slums worldwide, from Africa to Asia, face inadequate infrastructure, fostering health crises, and hindering progress toward sustainable development goals related to clean water and sanitation. Densely populated slums pose significant health risks due to poor waste management. This study examines the link between sanitation and health risks in 10 slums in Khulna, Bangladesh. The research evaluates 339 randomly selected households using a rapid assessment tool and a detailed survey, with ArcGIS aiding the sampling process. Findings reveal disparities in sanitation infrastructure, with private and public slums facing higher health risks than semi-public ones. About 70% of the slums have a composite risk score above 50%, and 40% are exposed to sanitation crises. Overall, the slums present medium-scale risks due to poor infrastructure, health hazards, and vulnerability. Addressing these challenges requires tackling hazards, exposure, and vulnerability, enhancing access to safe water and sanitation, reducing waterborne diseases, and fostering resilient urban infrastructure. Policymakers should invest in sanitation infrastructure, promote public health education, and implement action plans to improve living conditions in Khulna's slums.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"1-19"},"PeriodicalIF":2.2,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"How allergic conditions influence hygiene practices among adolescents: insights from a nationwide Youth Survey data.","authors":"Hyowon Choi, Seong Woong Yoon, Jeongmin Lee, Hunju Lee, Yeon-Soon Ahn","doi":"10.1080/09603123.2025.2489127","DOIUrl":"https://doi.org/10.1080/09603123.2025.2489127","url":null,"abstract":"<p><p>Effective handwashing is important for preventing exacerbation of allergic diseases, yet the relationship between allergic diseases in adolescents remains underexplored. Utilizing data from the Korea Youth Risk Behavior Survey (2009-2022), a nationwide study involving students aged 12-19, we analyzed the allergic condition, International Study of Asthma and Allergic Conditions (Never, Previous, Current), and their handwashing scores. We analyzed the trend of handwashing by allergic condition. And we conducted the ordinal logistic regression between allergic condition and handwashing, adjusted with gender, age, economic status, urbanization, smoking status, alcohol consumptions, surveyed year, and education on HW. A total of 3,258,610 adolescents were analyzed. We observed spikes in mean handwashing scores in 2009, 2013, 2015, and 2020, which corresponded with trends in allergic conditions. Adolescents with current asthma and allergic rhinitis had higher odds ratios (ORs) for better handwashing practices compared to those without these conditions. Conversely, those with current or previous atopic dermatitis had lower ORs compared to those without these conditions. In adolescent age, asthma and allergic rhinitis positively influence handwashing practices, while atopic dermatitis negatively influences handwashing practice, due to their comorbidities, highlighting the need for specialized handwashing guidelines that address the unique challenges of those with allergic diseases.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"1-11"},"PeriodicalIF":2.2,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quality assessment of online wildfire infographics in the United States.","authors":"Aliba Omar Syed, Saulat Jahan","doi":"10.1080/09603123.2025.2489666","DOIUrl":"https://doi.org/10.1080/09603123.2025.2489666","url":null,"abstract":"<p><p>In recent years, the occurrence of global and regional wildfires has increased. Wildfire infographics may serve as effective risk communication tools. In this cross-sectional study, we evaluated US based wildfire infographics posted online. Google search was initiated using the terms: \"wildfires,\" and \"infographics\". An evaluation tool was used to assess infographics on clear headings, content, font size, visual elements, color theme and overall design on a scale of 1-5. Data was analyzed using the Jamovi statistical software. Seventy-eight wildfire infographics were evaluated with most originating from California. Fact-based infographics (46.15%) predominated while few addressed prevention (6.41%). Forty-six infographics were high quality, 23 were medium quality and 9 were low quality. Governmental sources published 60.26%, of which 65.96% were high quality. Most of the high-quality infographics were text-light (65.21%) and icon-based (65%). A significant association was found between information type and text density (<i>p</i> = 0.005). Out of the total score of 30, the mean total infographic score was 24.85 ± 3.28. None of the infographics were customized for high-risk populations. We recommend creating wildfire prevention infographics targeting high risk populations. Further research is recommended to assess the effectiveness of the infographics.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"1-10"},"PeriodicalIF":2.2,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohd Amierul Fikri M, Faizul Akmal Ar, Eida Nurhadzira M, Mohd Hazrin H, Hanipah S, Izfa Riza H
{"title":"Spatial and breeding site analysis of <i>Aedes</i> spp. at dengue-prone areas in Kuala Lumpur, Malaysia.","authors":"Mohd Amierul Fikri M, Faizul Akmal Ar, Eida Nurhadzira M, Mohd Hazrin H, Hanipah S, Izfa Riza H","doi":"10.1080/09603123.2025.2488484","DOIUrl":"10.1080/09603123.2025.2488484","url":null,"abstract":"<p><p>Understanding Aedes breeding sites is crucial for effective vector control, yet the application of Geographic Information Systems (GIS) and spatial analysis in Kuala Lumpur is limited. This study explores the spatial distribution and characteristics of <i>Aedes aegypti</i> and <i>Aedes albopictus</i> breeding sites in dengue-prone areas of Bandar Tasik Selatan. Entomological data from the Kuala Lumpur Health Department (2022-2023) were analyzed using Average Nearest Neighbor (ANN), Global Moran's I, and Kernel Density Estimation (KDE). Logistic regression and principal component analyses (PCA) were used to assess breeding site characteristics. Of 6,027 water containers inspected, 402 (6.7%) were positive for Aedes larvae. ANN and Moran's I analyses revealed significant clustering in Zone A and Zone B, while KDE identified breeding hotspots. Logistic regression indicated higher risk in plastic (aOR = 69.58), rubber (aOR = 35.11), and cement (aOR = 24.70) containers, while rainwater (aOR = 0.24), tap water (aOR = 0.27), and partial shading (aOR = 0.41) reduced risk. PCA revealed key breeding site variations across residential, public, school, and food areas. These findings support targeted vector control, efficient resource allocation, and tailored interventions to mitigate dengue risks in high-priority areas.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"1-20"},"PeriodicalIF":2.2,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143811393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}