International Journal of Environmental Health Research最新文献

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Sleep quality and air pollution: evidence from patients attending Family Health Centers in a Turkish metropolitan city. 睡眠质量与空气污染:来自土耳其某大城市家庭健康中心患者的证据
IF 1.9 4区 医学
International Journal of Environmental Health Research Pub Date : 2025-10-14 DOI: 10.1080/09603123.2025.2574402
Tayyip Pak, Oğulcan Çöme, Gizem Limnili, Dilek Guldal
{"title":"Sleep quality and air pollution: evidence from patients attending Family Health Centers in a Turkish metropolitan city.","authors":"Tayyip Pak, Oğulcan Çöme, Gizem Limnili, Dilek Guldal","doi":"10.1080/09603123.2025.2574402","DOIUrl":"https://doi.org/10.1080/09603123.2025.2574402","url":null,"abstract":"<p><p>This cross-sectional study examined whether air pollution is linked to poorer sleep quality among 654 adults from two districts in Izmir, Turkey, with differing pollution levels.This study investigated whether increased air pollution is associated with reduced sleep quality.Adults aged 18-65 were recruited from Family Health Centers in Bayraklı (higher pollution) and Karşıyaka (lower pollution) between December 1-31, 2020. Air Quality Index and PM10 levels were obtained from local stations. Sleep quality was assessed using the Pittsburgh Sleep Quality Index. Sociodemographic, health, and behavioral data were collected via questionnaires.Poor sleep was reported by 15% of participants, more often in Bayraklı (18.8%) than Karşıyaka (11.1%) (p=0.006). Poor sleep correlated with older age, higher BMI, chronic disease, and medication use. Logistic regression showed that living in Karşıyaka was protective (OR=0.48, p=0.006), but this effect disappeared after adjusting for stove use (p=0.092). Stove use strongly predicted poor sleep (OR=5.11, p<0.001).Higher air pollution was associated with poorer sleep, and household coal/wood stove use was an independent risk factor. Public health measures promoting cleaner energy and managing chronic conditions may improve sleep outcomes.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"1-10"},"PeriodicalIF":1.9,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145286093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of cockroaches as mechanical carriers of helminth infections: a systematic review and meta-analysis of environmental and climatic impacts on public health. 蟑螂作为蠕虫感染的机械载体的作用:环境和气候对公众健康影响的系统回顾和荟萃分析。
IF 1.9 4区 医学
International Journal of Environmental Health Research Pub Date : 2025-10-10 DOI: 10.1080/09603123.2025.2571146
Milad Badri, Meysam Olfatifar, Samira Sabzi, Ali Asghari, Leila Zaki, Kareem Hatam-Nahavandi, Giovanni Sgroi, Amir Abdoli, Aida Vafae Eslahi
{"title":"The role of cockroaches as mechanical carriers of helminth infections: a systematic review and meta-analysis of environmental and climatic impacts on public health.","authors":"Milad Badri, Meysam Olfatifar, Samira Sabzi, Ali Asghari, Leila Zaki, Kareem Hatam-Nahavandi, Giovanni Sgroi, Amir Abdoli, Aida Vafae Eslahi","doi":"10.1080/09603123.2025.2571146","DOIUrl":"https://doi.org/10.1080/09603123.2025.2571146","url":null,"abstract":"<p><p>This study investigates the global prevalence of helminthic parasites in contaminated cockroaches, with a particular focus on identifying patterns based on climatic variable, geographic location, sample sources, detection methods, and cockroach species. From 2,884 articles, 39 articles had the eligibility to be included in the current study. The analysis revealed that the highest prevalence was found in household samples (0.399, 95% CI: 0.252-0.556). Specific species, such as <i>Blatta orientalis</i>, showed an exceptionally high prevalence of 0.885 (95% CI: 0.822 - 0.928). Regionally, Cameroon had the highest prevalence at 0.898 (95% CI: 0.856 - 0.934). Furthermore, environmental factors significantly influenced prevalence, with regions having annual precipitation over 1000 mm and humidity above 75% showing prevalence rates of 0.387 (95% CI: 0.164 - 0.638) and 0.590 (95% CI: 0.283 - 0.863), respectively. The findings indicate a significant global challenge posed by helminthic parasites associated with cockroaches, particularly in Africa and low-income settings. Higher prevalence rates correlate with factors such as household environments and specific detection methods, notably in regions characterized by warm and humid climates. These results underscore the necessity for targeted public health interventions and the implementation of effective pest management strategies to mitigate the risks associated with cockroach-related helminthiases.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"1-18"},"PeriodicalIF":1.9,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145274609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Corymbia terminalis kino extracts for antibacterial activity against wound-associated pathogens: bridging ethnopharmacology and experimental validation. 山茱萸kino提取物对伤口相关病原体的抗菌活性评价:连接民族药理学和实验验证。
IF 1.9 4区 医学
International Journal of Environmental Health Research Pub Date : 2025-10-09 DOI: 10.1080/09603123.2025.2573181
Marzieh Negahban, Chris Collet, Kamel Msaada, Trudi Collet
{"title":"Evaluation of <i>Corymbia terminalis</i> kino extracts for antibacterial activity against wound-associated pathogens: bridging ethnopharmacology and experimental validation.","authors":"Marzieh Negahban, Chris Collet, Kamel Msaada, Trudi Collet","doi":"10.1080/09603123.2025.2573181","DOIUrl":"https://doi.org/10.1080/09603123.2025.2573181","url":null,"abstract":"<p><p>Kino, a red resin from <i>Corymbia terminalis</i>, has long been used in Indigenous Australian medicine for wound care, but its antimicrobial properties remain underexplored. This study assessed the antibacterial efficacy of kino extracts against 19 wound-colonizing bacterial strains using well diffusion (WDA), minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) assays. Extracts were prepared using various organic solvents and water-based methods, including hot/cold infusion, crude aqueous extraction, and sequential solvent extractions. All kino extracts demonstrated bactericidal activity against all 19 wound-associated bacterial strains, with the methanolic and crude aqueous extracts producing the largest inhibition zones (up to 8.96 ± 0.49 mm) and the lowest MIC values (as low as 2 μg/mL). MICs ranged from 2 to 64 μg/mL, while MBCs ranged from 20 to 100 mg/mL, reflecting the higher concentrations typically required for bactericidal activity. Hot-start infusions retained antimicrobial activity, suggesting thermostability of active compounds. While organic solvents improved extraction efficiency, water-based preparations - commonly used in traditional medicine - also yielded substantial antimicrobial effects. The data affirm the potential of <i>C. terminalis</i> kino as a natural antimicrobial agent and validate its ethnopharmacological use in wound management. Future studies should isolate and characterize its active constituents and evaluate <i>in vivo</i> efficacy.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"1-13"},"PeriodicalIF":1.9,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in PM₂.₅ and mortality risks in an industrial District of Taiwan: a 12-year analysis. PM₂的趋势。台湾某工业区的₅和死亡风险:12年分析
IF 1.9 4区 医学
International Journal of Environmental Health Research Pub Date : 2025-10-08 DOI: 10.1080/09603123.2025.2568695
Yu-Hsiang Tsao, Joh-Jong Huang, Chih-Hsing Hung, Su-Hong Chang, Hui-Min Hsieh
{"title":"Trends in PM₂.₅ and mortality risks in an industrial District of Taiwan: a 12-year analysis.","authors":"Yu-Hsiang Tsao, Joh-Jong Huang, Chih-Hsing Hung, Su-Hong Chang, Hui-Min Hsieh","doi":"10.1080/09603123.2025.2568695","DOIUrl":"https://doi.org/10.1080/09603123.2025.2568695","url":null,"abstract":"<p><p>Ambient air pollution, particularly fine particulate matter (PM₂.₅), poses a major global public health concern. We examined trends in all-cause and respiratory disease-specific mortality and their association with PM₂.₅ concentrations during three time periods (2008-2011, 2012-2015, 2016-2019) in Linyuan District, Kaohsiung City, and Taiwan, using generalized Poisson mixed models. PM₂.₅ concentrations declined by 23.6% in Taiwan, from 24.5 µg/m<sup>3</sup> (2008-2011) to 18.8 µg/m<sup>3</sup> (2016-2019), with similar reductions observed in Kaohsiung City and Linyuan District. Age-standardized all-cause mortality rates also decreased over time. Nevertheless, residents of Linyuan consistently exhibited higher mortality than those in Kaohsiung City and Taiwan. Each 1 µg/m<sup>3</sup> increase in PM₂.₅ was associated with higher all-cause mortality risk (men: RR = 1.011, 95% CI: 1.001-1.021; women: RR = 1.017, 95% CI: 1.004-1.031). Despite overall declines in PM₂.₅ and mortality rates, excess risks persist in heavily industrialized areas. These findings highlight the public health benefits of air-quality improvements and the need for sustained pollution control efforts. In addition, as this study is observational and ecological in nature, the findings should be interpreted with caution and not as evidence of causality.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"1-12"},"PeriodicalIF":1.9,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145244526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identifying interventions to support mental health for those affected by climate change and related extreme weather events: a scoping review. 确定支持受气候变化和相关极端天气事件影响者心理健康的干预措施:范围审查。
IF 1.9 4区 医学
International Journal of Environmental Health Research Pub Date : 2025-10-08 DOI: 10.1080/09603123.2025.2568035
Masuma Pervin Mishu, Mm Golam Rabbani, Silke Vereeken, Emma Tkach, Jacqueline Martin-Kerry, T Faiaz Chowdhury, Abrar Wahab, Saidur Rahman Mashreky, Rumana Huque, Richard Friend
{"title":"Identifying interventions to support mental health for those affected by climate change and related extreme weather events: a scoping review.","authors":"Masuma Pervin Mishu, Mm Golam Rabbani, Silke Vereeken, Emma Tkach, Jacqueline Martin-Kerry, T Faiaz Chowdhury, Abrar Wahab, Saidur Rahman Mashreky, Rumana Huque, Richard Friend","doi":"10.1080/09603123.2025.2568035","DOIUrl":"https://doi.org/10.1080/09603123.2025.2568035","url":null,"abstract":"<p><p>We aimed to identify interventions to support mental health for those affected by climate change and related extreme weather events. We conducted a scoping review in accordance with standard guidelines, searching five databases. We identified 26 studies. All twenty-six included studies (one on the overall impact of climate change, eleven on storms, nine on flooding, and five on wildfires) reported different types of interventions and demonstrated the effectiveness of these interventions in improving mental health outcomes. Most of the interventions were conducted in high-income countries, targeted at the individual level, delivered by specialist or non-specialists, and based on Cognitive Behavioural Therapy (CBT) in different forms (face-to-face, online, mobile phone text messages, etc.). There are few studies available on interventions at community and family support, and on basic services delivered to those exposed to extreme weather events. Given that climate change projections indicate intensified frequency, severity and scale of such extreme weather events, there is a need for multi sectoral coordinated interventions targeting the individual, community support and basic services at system level that are tailored to the specific nature of extreme weather events, the kinds of impact they create, and the needs and circumstances of those who are impacted.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"1-27"},"PeriodicalIF":1.9,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145244411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing exposure of young children to air pollutants in urban homes in Alexandria, Egypt. 评估埃及亚历山大城市家庭中幼儿暴露于空气污染物的情况。
IF 1.9 4区 医学
International Journal of Environmental Health Research Pub Date : 2025-10-08 DOI: 10.1080/09603123.2025.2572407
Mahmoud M M Abdel-Salam
{"title":"Assessing exposure of young children to air pollutants in urban homes in Alexandria, Egypt.","authors":"Mahmoud M M Abdel-Salam","doi":"10.1080/09603123.2025.2572407","DOIUrl":"10.1080/09603123.2025.2572407","url":null,"abstract":"<p><p>Sensitive groups, including infants and children, spend much or even all of their time at home and are more exposed to household air pollutants at higher concentrations. Due to behavioral and physiological reasons, young children under the age of 5 are at higher risk when compared to adults from exposure to indoor air pollution. Indoor and outdoor monitoring of particulate matter (PM<sub>10</sub> and PM<sub>2.5</sub>) and gaseous pollutants (CO and CO<sub>2</sub>) were performed in 45 urban homes in Alexandria city, Egypt during the winter season. Occupants were requested to complete a questionnaire and time activity diary to collect information on building characteristics (home area, home age, floor level, etc.), indoor activities (smoking, cooking, and cleaning), and time spent by young children in different microenvironments. Results indicated that young children spent 97.5% of time indoors (49.8% in bedrooms and 47.7% in living rooms). Living rooms showed the largest contribution to the daily average exposure of young children to PM<sub>2.5</sub>, PM<sub>10</sub>, and CO with average values of 59.7%, 59.3%, and 63.9%, respectively. For CO<sub>2</sub>, bedrooms showed the highest contribution to the daily average exposure of young children with an average value of 53.2%. Daily average children's exposures to PM<sub>10</sub> (96.1 ± 21.3 μg/m<sup>3</sup>) and PM<sub>2.5</sub> (65.5 ± 17.0 μg/m<sup>3</sup>) exceeded the WHO guidelines which is of high risk for their health. Daily average children's exposures to CO (0.8 ± 0.5 ppm) and CO<sub>2</sub> (772.7 ± 74.7 ppm) were below the WHO guideline and the ASHRAE Standard 62.1, respectively. Factors that are most likely to lead to high children's exposures to PM<sub>10</sub> and PM<sub>2.5</sub> in homes are outdoor sources (e.g. traffic emissions) and indoor human activities (e.g. smoking, cooking, and cleaning). Specific mitigation measures at the household level associated with policies and regulation for outdoor air pollution can have considerable impact on reducing children's exposure and protect their health.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"1-16"},"PeriodicalIF":1.9,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145244350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Network toxicology, molecular docking and molecular dynamics simulation to explore the potential mechanism of nonylphenol induced cardiotoxicity. 网络毒理学、分子对接、分子动力学模拟,探讨壬基酚诱导心脏毒性的潜在机制。
IF 1.9 4区 医学
International Journal of Environmental Health Research Pub Date : 2025-10-05 DOI: 10.1080/09603123.2025.2563057
Nana Huang, Yuanyuan Xiao, Xiaoyue Zhang, Yue Pan, Yonghong Xu, Fang Peng, Wenchao Tang
{"title":"Network toxicology, molecular docking and molecular dynamics simulation to explore the potential mechanism of nonylphenol induced cardiotoxicity.","authors":"Nana Huang, Yuanyuan Xiao, Xiaoyue Zhang, Yue Pan, Yonghong Xu, Fang Peng, Wenchao Tang","doi":"10.1080/09603123.2025.2563057","DOIUrl":"https://doi.org/10.1080/09603123.2025.2563057","url":null,"abstract":"<p><p>This study aims to elucidate the potential mechanism of cardiotoxicity induced by nonylphenol (NP) through network toxicology, molecular docking and molecular dynamics simulation. With the help of Swisstarget prediction, the comparative toxicology database and genecards database, 197 genes related to NP-induced cardiac toxicity were identified as Potential target. Using the STRING database and cytoscape 3.10.1 software, 8 core targets (such as AKT1, MAPK3, STAT3) were further screened. GO and KEGG enrichment analyses showed that NP mainly affects PI3K-Akt, MAPK and JAK-STAT pathways, regulating cell apoptosis and inflammation. Molecular docking demonstrated that NP stably binds to the core target, and molecular dynamics simulations further verified the stability of the NP-MAPK3 complex, with a binding free energy of -1.215 kcal/mol, and the system exhibits good stability. In conclusion, NP may induce cardiotoxicity by interfering with PI3K-Akt, MAPK and other signaling pathways. This research provides a multi-dimensional methodological framework for analyzing the toxic mechanism of environmental pollutants, and lays the theoretical foundation for risk assessment and prevention strategies.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"1-13"},"PeriodicalIF":1.9,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mapping the environmental risk of coccidioidomycosis in Sonora, Mexico: a Bayesian spatiotemporal perspective (2010-2022). 绘制墨西哥索诺拉球虫菌病的环境风险:贝叶斯时空视角(2010-2022)。
IF 1.9 4区 医学
International Journal of Environmental Health Research Pub Date : 2025-10-02 DOI: 10.1080/09603123.2025.2566245
Laura Rosio Castañón-Olivares, Edith Sánchez-Paredes, José Mauricio Galeana-Pizaña
{"title":"Mapping the environmental risk of coccidioidomycosis in Sonora, Mexico: a Bayesian spatiotemporal perspective (2010-2022).","authors":"Laura Rosio Castañón-Olivares, Edith Sánchez-Paredes, José Mauricio Galeana-Pizaña","doi":"10.1080/09603123.2025.2566245","DOIUrl":"10.1080/09603123.2025.2566245","url":null,"abstract":"<p><p>Coccidioidomycosis, a fungal disease caused by <i>Coccidioides</i> spp. is endemic in arid regions of the Americas. Although northern Mexico shows increasing incidence, its environmental determinants remain understudied. This research examines the association between coccidioidomycosis and environmental factors in Sonora, Mexico, from 2010 to 2022. We integrated municipal-level hospital discharge data with mean annual temperature, total annual precipitation, wind speed and direction, soil moisture, vegetation index and land use (human settlements and agriculture). Using a Bayesian hierarchical spatiotemporal model with a second-order random walk structure, we estimated posterior relative risk. Results indicate that higher mean annual temperature, total annual precipitation, and wind patterns were associated with increased hospitalization rates, whereas greater vegetation cover and soil moisture were associated with reduced rates. Spatial heterogeneity in posterior relative risk was substantial, with hotspots detected in municipalities such Hermosillo, Cajeme and Caborca showing marked increases. These results contribute to a better understanding of the dynamic environmental factors influencing coccidioidomycosis acquisition, which can inform more effective public health strategies. However, to improve future risk prediction and disease prevention, it will be necessary to also consider immunological, genetic, and lifestyle factors among populations living in endemic areas.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"1-15"},"PeriodicalIF":1.9,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low-level environmental lead exposure alters serum metabolic profiles in preschool children. 低水平环境铅暴露改变学龄前儿童血清代谢谱。
IF 1.9 4区 医学
International Journal of Environmental Health Research Pub Date : 2025-09-29 DOI: 10.1080/09603123.2025.2564302
Lichun Qiao, Liangjia Wang, Miaoye Bao, Miaoqian Li, Shaoteng Shi, Ping Wan, Huan Deng, Jing Han
{"title":"Low-level environmental lead exposure alters serum metabolic profiles in preschool children.","authors":"Lichun Qiao, Liangjia Wang, Miaoye Bao, Miaoqian Li, Shaoteng Shi, Ping Wan, Huan Deng, Jing Han","doi":"10.1080/09603123.2025.2564302","DOIUrl":"https://doi.org/10.1080/09603123.2025.2564302","url":null,"abstract":"<p><p>Environmental lead (Pb) exposure has been recognized as a significant public health concern, with high levels of exposure leading to serious health damage. However, the effects of exposure to lower levels of Pb on health are poorly understood, especially in preschool children. This study aimed to investigate the impact of Pb exposure on serum metabolic profiles in preschool children and screen for potential biomarkers. Forty-two preschool children were included. The blood samples were collected to detect the serum metabolomics. The urine samples were also collected to quantify the urinary Pb and creatinine concentrations. Orthogonal projections of potential structure discrimination analyses were used to assess intergroup metabolite differences. Receiver operating characteristic curves were used to screen for biomarkers. The results showed that environmental Pb exposure could cause serum metabolic disturbances in preschool children, mainly involving disturbances in lipid, amino acid, and carbohydrate metabolism. Beta-doradecin, traumatic acid, 5(S)-HpETE and 1-Hexanethiol have been identified as potential biomarkers. In conclusion, exposure to low levels of environmental Pb can disrupt metabolic homeostasis in preschool children, primarily affecting normal neural development and energy metabolism. This study provides new insights into the possible health hazards associated with low-level environmental Pb exposure in preschool children.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"1-12"},"PeriodicalIF":1.9,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145185645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of PM2.5 with hypertension, type 2 diabetes, and multimorbidity: evidence from the China Migrants Dynamic Survey of 165,075 individuals. PM2.5与高血压、2型糖尿病和多种疾病的关系:来自165,075名中国移民动态调查的证据
IF 1.9 4区 医学
International Journal of Environmental Health Research Pub Date : 2025-09-29 DOI: 10.1080/09603123.2025.2562028
Yang Zhao, Hongyu Li, Cao Zhang, Shijia Yuan, Surong Zhao, Chunlei Han
{"title":"Association of PM<sub>2.5</sub> with hypertension, type 2 diabetes, and multimorbidity: evidence from the China Migrants Dynamic Survey of 165,075 individuals.","authors":"Yang Zhao, Hongyu Li, Cao Zhang, Shijia Yuan, Surong Zhao, Chunlei Han","doi":"10.1080/09603123.2025.2562028","DOIUrl":"https://doi.org/10.1080/09603123.2025.2562028","url":null,"abstract":"<p><p>This study aims to investigate the relations of exposure to ambient PM<sub>2.5</sub> with hypertension, type 2 diabetes, and multimorbidity among the Chinese mobile population. The study used the China Migrants Dynamic Survey (CMDS) data, PM<sub>2.5</sub> and Meteorological data in 2017. Binary logistic regression models were performed to examine the relationships between PM<sub>2.5</sub> and chronic diseases in mobile population after adjusting for covariates. Overall, each tertile increase in PM<sub>2.5</sub> was associated with increased odds of hypertension (OR = 1.047, 95% CI: 1.013-1.082), type 2 diabetes (OR = 1.095, 95% CI: 1.014-1.182) and multimorbidity (OR = 1.098, 95% CI: 1.005-1.199) in mobile population. Greater OR for association of PM<sub>2.5</sub> with multimorbidity than a single disease. Stratified analyses revealed that males were susceptible to PM<sub>2.5</sub>-related hypertension and diabetes, and females were susceptible to PM<sub>2.5</sub>-related multimorbidity. The older and people with low incomes were more likely to be affected by PM<sub>2.5</sub> to develop hypertension, type 2 diabetes, and multimorbidity. This study suggested that PM<sub>2.5</sub> was associated with hypertension, type 2 diabetes, and multimorbidity in Chinese mobile population. The elderly and those with low incomes mobile population were susceptible to PM<sub>2.5</sub>. Effective strategies for air pollution reduction should be taken by local policymakers to further improve the migrants' health status.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":" ","pages":"1-14"},"PeriodicalIF":1.9,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145185707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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