International Journal of Contemporary Medical Research [IJCMR]最新文献

{"title":"Study of Glycated Haemoglobin and Lipid Profile in Patients with Diabetic Foot Ulcer","authors":"S. Mushtaq, S. Khan, M. Rashid","doi":"10.21276/ijcmr.2020.7.6.17","DOIUrl":"https://doi.org/10.21276/ijcmr.2020.7.6.17","url":null,"abstract":"Introduction: Diabetic foot ulcer is a major disabling complication of Diabetes Mellitus and often precedes lower extremity amputation. This study aims to evaluate the level of HbA1c and lipid profile in patients with diabetic foot ulcer as T2DM patients are prone to diabetic dyslipidemia,which puts them at risk of developing macrovascular and microvascular diseases. Material and methods: The study was accomplished at a tertiary care hospital in Jammu & Kashmir. One hundred ten subjects with T2DM were enrolled for the present study, this included 55 subjects with DFU and 55 subjects without DFU. The HbA1c and lipid profile of the subjects were measured with standard methods. Results: In our study HbA1c level was found higher in diabetic patients with diabetic foot ulcer when compared with patients without. Also lipid profile was found deranged in diabetic foot ulcer patients in comparison to control group. It was found that approximately 78% DFU have HbA1c levels ˃7%. Unlike the DFU-patients, 79% of patients without DFU have HbA1c level controlled. Conclusion: As diabetic foot ulcer is a major disabling complication of Diabetes Mellitus and often precedes lower extremity amputation, we conclude that HbA1c level should be maintained in normal range and regulating it is imperative for avoiding T2DM complications.","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"2012 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86392416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Immunohistochemistry in Diagnosis and Subtyping of Acute Leukemia using Selected IHC Markers in a Resource Limited Setting","authors":"S. Pant, R. Misra","doi":"10.21276/ijcmr.2020.7.6.15","DOIUrl":"https://doi.org/10.21276/ijcmr.2020.7.6.15","url":null,"abstract":"Introduction: In resource limited settings where genetic studies and flow cytometry were not routinely done or available, morphology is primarily used for diagnosis and subtyping of acute leukemias with use of ancillary tests like cytochemistry and immunohistochemistry in selected cases for a more accurate and definitive diagnosis. This study was done to assess the role of immunohistochemistry in diagnosis and subtyping of acute leukemias in resource poor setting using selected IHC markers and to find diagnostic accuracy of morphologic diagnosis. Material and methods: The study was done on 45 selected cases of acute leukemia. Immunohistochemistry was done on all cases for typing and confirmation of diagnosis after morphological examination of peripheral blood smears and all three bone marrow preparations.A limited panel of IHC markers were used including Anti MPO, Anti CD3, Anti CD20, Anti CD22, Anti TdT, Anti CD117, Anti CD15 and Anti CD68(KP1) for immunohistochemistry. Results: The accuracy of morphological diagnosis in cases of AML and ALL in the study was 84.09% and 82.22% respectively. By intercalating immunohistochemical studies with morphological examination almost all cases of acute leukemia can be diagnosed and subclassified, and diagnostic accuracy is increased as compared to morphological examination alone. Conclusion: Though morphology remains the gold standard for paraffin embedded bone marrow trephines,immunohistochemical staining has became an integral part of diagnostic workup in cases of hematologic malignancies in limited resource settings.","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80493542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Study of Nutritional Health Problems of Adolescent Girls in Rural Area of Nagpur District: A School Based Cross Sectional Study","authors":"S. Thakre, Subhash B. Thakre, Priti N. Tiwari, Hitesh C. Tayade","doi":"10.21276/ijcmr.2020.7.6.34","DOIUrl":"https://doi.org/10.21276/ijcmr.2020.7.6.34","url":null,"abstract":"Introduction: \"Adolescence\" literally means \"to emerge\" or \"to attain identity\" and is essentially the period of rapid physical and psychological development. The World Health Organization (WHO) defines “adolescent” as an individual between 10 to 19 years of age. About 19.7% of Indian population is adolescents. Nutritional health problems are one of the important health problem faced by adolescents. Prevalence of anemia in adolescents (15-19 years) girls is 54%. Underweight is seen among 46.4% adolescent girls. Hence this study was conducted to find out nutritional health problems of adolescent girls in a rural area of Nagpur district. Menstrual hygiene was also studied. Material and methods: A cross sectional study was carried out in one of the randomly selected school in a rural area of Nagpur. Calculated sample size was 145, though the study was carried out on 150 adolescent girls in August 2019 using a pre-designed and pretested questionnaire. Results: Mean age of study participants was 14.87± 2.77 years. Prevalence of anemia was found to be 80%. Prevalence of undernutrition was 36%. None of the student received weekly iron and folic acid tablets in last three months. Only 28% study subjects received information of menstrual hygiene prior to menarche. Conclusion: Prevalence of anemia and undernutrition was found to be high in a school of rural area of Nagpur district. WIFS program should be strengthened through inter-sectoral collaboration among health and education sectors.","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"155 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76744299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paratubal Atypical Proliferative Serous Tumour in a Young Adolescent Female - A Diagnostic Dilemma","authors":"M. Garg, N. Kaur, Kanwardeep Kaur, Amrinder Kaur, C. Chandrika","doi":"10.21276/ijcmr.2020.7.3.34","DOIUrl":"https://doi.org/10.21276/ijcmr.2020.7.3.34","url":null,"abstract":"Introdcution: Paratubal atypical proliferative serous tumours are rare usually arising from the mesothelium or from the remnants of mesonephric and paramesonephric ducts. We present a rare case of paratubal borderline serous tumour in a young adolescent female presenting clinically as an omental cyst. Case Report: A 14-year old unmarried female presented with abdominal pain in right iliac fossa. MRI revealed a well demarcated space occupying lesion in the pelvis almost in midline measuring 12x11x8cm. Lesion was abutting and displacing overlying bowel loops with likely adhesions suggestive of complex omental cyst. The patient underwent cystectomy. The final histopathologic report confirmed the cyst as Paratubal atypical proliferative serous tumour. Conclusion: We experience a rare case of atypical proliferative serous tumour of paratubal origin. The patient was youngest than any of the other cases reported in the literature. Fertility sparing surgery should be considered as a standard treatment of borderline paratubal tumour, if patient desires future","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79715947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Evaluation of Three Different Pit and Fissure Sealants","authors":"Ifzah Ifzah, Saranya Kumar","doi":"10.21276/ijcmr.2020.7.3.15","DOIUrl":"https://doi.org/10.21276/ijcmr.2020.7.3.15","url":null,"abstract":"Introduction: Dental caries is an infectious mulifactorial disease which can affect any tooth in the oral cavity. As such it is important to protect them from becoming carious. Resin sealant methods developed by Bowen in 1962 still continue to form the basis of presently available sealants. An important factor for sealant success is its marginal integrity and retention. Hence this study was undertaken to assess the retention and marginal discoloration of conventional pit and fissure sealants, Glass ionomer sealant type VII and Helioseal-F. Study aimed to assess the retention and marginal discoloration of conventional pit and fissure sealants, glass ionomer sealant type VII and helioseal -F. Material and methods: This study was conducted in a private dental clinic in Bangalore from 2015 to 2016. Thirty children aged 6 to 8 years were selected. The children were divided into 3 groups of 10 children each. First group, ortho Phosphoric acid etchant gel was applied with a disposable nylon applicator tip on to the pit and fissures. Conventional light-cured resinbased pit-and-fissure sealant (ClinproTM Sealant (3M ESPE) was cured with the light curing unit for 20 seconds. Second group (Group II): Fuji VII cement was mixed according to manufacturer’s instructions and applied to the occlusal surface using a plastic-filling instrument and a disposable nylon brush to spread it into the pits and fissures. Third Group (Group III): Etching was done with 37% phosphoric acid for 20 seconds. Using the syringe needle tip, Helioseal F sealant was flowed into the fissures for 20 seconds. First follow up examination was done at 3 months recall by using visual and tactile examination. The sealants were examined for their integrity, retention and marginal discoloration. The data was obtained at 3 months and 6 months intervals. The teeth were visually inspected for caries. Results: At 3-month evaluation 89.7% of retention was seen for conventional resin sealant, 72.7% retention for Helioseal F and 65.3% for Glass ionomer sealant. At 6month follow up 73.3% retention was seen for conventional resin sealant, 52.4% retention for Helioseal F and 34.9% for Glass ionomer sealant. There was no significant difference in terms of marginal discoloration between conventional resin sealant and helioseal F. However glass ionomer sealant showed a significant marginal discoloration as compared to helioseal F. No significant differe-nce was seen in the development of caries between the three groups. Conclusion: Conventional sealants are better sealants with respect to retention.","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"136 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81744085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osseous Metaplasia in Leiomyoma: Case Report with Literature Review","authors":"P. Kaur, M. Garg, Veerpal Kaur, M. Monika, Ira Moudgil","doi":"10.21276/ijcmr.2020.7.3.33","DOIUrl":"https://doi.org/10.21276/ijcmr.2020.7.3.33","url":null,"abstract":"Introduction: Leiomyoma is being one of the commonest tumors of the female genital tract during the reproductive years. It is a benign neoplasm of smooth muscle. Case report: We present one such case in a 60 year old postmenopausal female patient presented with uterovaginal prolapse. Conclusion: The leiomyoma demonstrate a wide spectrum of histological variation, but osseous metaplasia is a rare clinical entity. Keyword: Leiomyoma, Neoplasm, Metaplasia, Osseous,","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77736253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role and Clinical efficacy of Subconjunctival Injection Bevacizumab in Nonsurgical Management of Pterygium","authors":"S. Gaur, Vivek Sharma","doi":"10.21276/ijcmr.2020.7.3.40","DOIUrl":"https://doi.org/10.21276/ijcmr.2020.7.3.40","url":null,"abstract":"Introduction: Pterygium progression and recurrence is a common complication. In various studies conducted on role of subconjunctival depot injection of bevacizumab, nothing has been standardized with regards to dosage and its frequency. The study was done with aim to assess role and clinical efficacy of subconjunctival injection of bevacizumab as a non surgical treatment modality for pterygium. Material and Methods: 80 cases of pterygium were included in this study. Study was done over a period of 12 months from December 2018 to November 2019 at a tertiary care ophthalmic centre of Northern India. In this study, three doses of 2.5 mg of bevacizumab were administered sub-conjunctivally at monthly interval under topical anaesthesia on Outdoor Patient Department basis. Standard aseptic measures were observed. Results: Cases were followed up next day after each injection and thereafter on monthly basis for three months and finally after 06 months of first injection. Progression of pterygium was noted in 8 cases. Subconjunctival haemorrhage was noted in 41 cases. Conjunctival cyst was seen in three cases which were punctured in OPD, however recurrence was noted after one month in one case. No rise in Intra Ocular Pressure (IOP) was noted. Conclusions: Subconjunctival injection of bevacizumab is useful in treatment of patients with pterygium without local or systemic adverse effects.","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84286027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of Glycosylated Haemoglobin (Hba1c) Levels in Non-Diabetic Patients with Hypothyroidism","authors":"N. R. A., P. K G","doi":"10.21276/ijcmr.2020.7.3.27","DOIUrl":"https://doi.org/10.21276/ijcmr.2020.7.3.27","url":null,"abstract":"Introduction: HbA1c used for the assessment of glycemic status of the diabetic patients is widely recommended for its use for diagnosing diabetes. A positive association between thyroid disorder and diabetes mellitus is well recognized but to study the effect of thyroid disorders on glucose metabolism in non diabetic patients is an area for extensive research. Objective of the study was to study the glycosylated haemoglobin (HbA1c) levels in Non diabetic patients with hypothyroidism. Material and methods: Patients attending teaching hospitals attached to BMCRI who fulfilled the inclusion criteria were taken into study during the period from November 2017-May 2019. It was a cross sectional study. Descriptive statistics like mean, standard deviation were calculated. Inferential statistics like Mann-whitney test was used to compare the parameters between two groups. Results: During the period of study, 130 patients were studied of these, 65 were cases who were non diabetic patients with hypothyroidism, 65 controls who were non diabetic euthyroid patients. Among 65 cases 5 patients had normal HbA1C levels (7.7%) and 60 patients had increased HbA1C levels (Prediabetes) (92.3%), among 65 controls 56 patients had normal HbA1C levels (86.2%) and 9 patients had increased HbA1C levels (13.8%). Conclusion: From the results of the present study it can be concluded HbA1c levels were significantly higher in non diabetic patients with hypothyroidism when compared to non diabetic patients with normal thyroid function (mean HbA1C levels were 5.87± 0.23 vs 5.42 ± 0.24) (P <0.0001) which was statistically significant. Therefore it is suggested that the effects of the hypothyroidism on the HbA1c must be considered when interpreting the HbA1c for the diagnosis of prediabetes.","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"141 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76195562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Masculinisation with Increasing Parity in Agroha Village of Haryana","authors":"Pooja Kataria, S. Choudhary, Neelu Saluja, S. Pandey","doi":"10.21276/ijcmr.2020.7.3.16","DOIUrl":"https://doi.org/10.21276/ijcmr.2020.7.3.16","url":null,"abstract":"Introduction: The proportion of girls “missing” has risen sharply, there are obvious moral and human concerns generated by such extreme manifestation of gender inequity. In India, increase in overall sex ratio shown by the 2011 census is applauded at several forums. However, decline in the child sex ratio i.e. number of girls to boys in 0-6 years age group fell from 927 in 2001 to 914 in 2011. It is the lowest since independence. Haryana is among the most affected state regarding imbalance of child sex ratio. Therefore, this study was conducted to assess the present child sex ratio and its trend in Agroha village of Haryana. Material and Methods: This community based cross sectional study was conducted in Agroha village of Haryana. Five hundred and fifteen mothers having children in the age group of less than 6 years were selected for the study. The primary tool in this study was predesigned and pretested interview schedule for recording of family and individual information. Data were analyzed by using appropriate statistical tests (viz. Proportions, Mean ± SD, Chi-square test etc.). Results: With increasing parity significant decline in child sex ratio was observed. Sex Ratio for 1st birth order children was 929 females per 1000 males. It fell in the 2nd birth order to 830, 3rd birth order to 699, 4th birth order to 462, 5th birth order to 417 and still further to only 308 for 6th birth order. There was a significant linear relationship between adverse child sex ratio in the study population with increasing birth order. Conclusion: As masculinisation with increasing parity was observed in the study area, it is concluded that Haryana has yet a long way to go in her fight against declining child sex ratio.","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76123801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eccrine Spiradenoma","authors":"M. Murali Krishna, Y. S. Sarma, M. Srihari Babu","doi":"10.21276/ijcmr.2020.7.2.7","DOIUrl":"https://doi.org/10.21276/ijcmr.2020.7.2.7","url":null,"abstract":"","PeriodicalId":13918,"journal":{"name":"International Journal of Contemporary Medical Research [IJCMR]","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88425603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}