Study of Glycated Haemoglobin and Lipid Profile in Patients with Diabetic Foot Ulcer

Abstract

Introduction: Diabetic foot ulcer is a major disabling complication of Diabetes Mellitus and often precedes lower extremity amputation. This study aims to evaluate the level of HbA1c and lipid profile in patients with diabetic foot ulcer as T2DM patients are prone to diabetic dyslipidemia,which puts them at risk of developing macrovascular and microvascular diseases. Material and methods: The study was accomplished at a tertiary care hospital in Jammu & Kashmir. One hundred ten subjects with T2DM were enrolled for the present study, this included 55 subjects with DFU and 55 subjects without DFU. The HbA1c and lipid profile of the subjects were measured with standard methods. Results: In our study HbA1c level was found higher in diabetic patients with diabetic foot ulcer when compared with patients without. Also lipid profile was found deranged in diabetic foot ulcer patients in comparison to control group. It was found that approximately 78% DFU have HbA1c levels ˃7%. Unlike the DFU-patients, 79% of patients without DFU have HbA1c level controlled. Conclusion: As diabetic foot ulcer is a major disabling complication of Diabetes Mellitus and often precedes lower extremity amputation, we conclude that HbA1c level should be maintained in normal range and regulating it is imperative for avoiding T2DM complications.