International journal of Advanced Biological and Biomedical Research最新文献_第8页

Bioorganic investigation of encapsulated Cysteine derivative into polymeric nanocarrier 半胱氨酸衍生物包封聚合物纳米载体的生物有机研究

International journal of Advanced Biological and Biomedical Research Pub Date : 2019-10-01 DOI: 10.33945/SAMI/IJABBR.2019.4.6

Ehab M. M. Ali, A. Hamed

{"title":"Bioorganic investigation of encapsulated Cysteine derivative into polymeric nanocarrier","authors":"Ehab M. M. Ali, A. Hamed","doi":"10.33945/SAMI/IJABBR.2019.4.6","DOIUrl":"https://doi.org/10.33945/SAMI/IJABBR.2019.4.6","url":null,"abstract":"In this work, the copolymer-based synthesized Cysteine-loaded nanocarriers prepared by a routine protocol, coprecipitation method. It is the first report to investigate the neuroprotective potential and biocompatibility of Cysteine derivatives loaded into poly(ethylene glycol)-block-poly(e−caprolactone) methyl ether (PEG-b-PCL). The average size of the polymeric/empty NCs was 89 nm and for polymeric/Synthesized derivative of Cysteine was 126 nm. The Drug Loading efficiency was 81%. The concentration of Polymeric NCs was 2.1 x 10 10 particles/ml and the zeta potential of polymeric/empty and polymeric/ Synthesized derivative of Cysteine NCs -5 mV and -11 mV respectively. Biological part of this work were investigated in the SH-SY5Y human neuroblastoma cell line using cell viability and toxicity assays. The concentration of polymeric NCs below 1 x 10 10 particles/ml described as a zero-point damageable for the cell line. Also the Synthesized derivative of Cysteine encapsulated into polymeric NCs have more neuroprotective effect compared to free Cysteine at lower concentration, and therefore, have a significant neuroprotective potential against Z-VAD-fmk and St-evoked SH-SY5Y cell damage.","PeriodicalId":13887,"journal":{"name":"International journal of Advanced Biological and Biomedical Research","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85973981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effect of sub-effective dose of GABA agonists on attenuation of morphine tolerance in rats: Behavioral and electrophysiological studies 亚有效剂量GABA激动剂对大鼠吗啡耐受减弱的影响:行为学和电生理研究

International journal of Advanced Biological and Biomedical Research Pub Date : 2019-10-01 DOI: 10.33945/sami/ijabbr.2019.4.4

H. Manaheji, S. Mehrabadi

引用次数: 2

Heamatology, Serum Biochemistry, Relative Organ Weight and Bacteria Count of Broiler Chicken Given Different Levels of Luffa Aegyptiaca Leaf Extracts 饲喂不同水平埃及丝瓜叶提取物对肉鸡血液学、血清生化、相对脏器重量和细菌数量的影响

International journal of Advanced Biological and Biomedical Research Pub Date : 2019-10-01 DOI: 10.33945/SAMI/IJABBR.2019.4.8

A. John

{"title":"Heamatology, Serum Biochemistry, Relative Organ Weight and Bacteria Count of Broiler Chicken Given Different Levels of Luffa Aegyptiaca Leaf Extracts","authors":"A. John","doi":"10.33945/SAMI/IJABBR.2019.4.8","DOIUrl":"https://doi.org/10.33945/SAMI/IJABBR.2019.4.8","url":null,"abstract":"The objective of this study was to evaluate the heamato-biochemical, relative organ weight and bacteria count of broiler chicken given different levels of Luffa aegyptiaca leaf extract (LUF). A total of 250 day old Ross 308 broiler chicks of mixed sex were divided into five treatments, each group was further divided into five replicates each of ten (10) birds in a completely randomized design. Birds in treatment A were given 1.20g/litre of Neomycin in water, treatment B, C, D and E were given 5, 10, 15 and 20 ml/litre of LUF. Clean feed and water was given ad libitum and the experiment lasted for 3 weeks. The data obtained was used to evaluate the haematological parameters (PCV, RBC, Hb, WBC, MCV, MCH and MCHC), serum biochemical indices (Albumin, globulin, calcium, phosphorus, SGPT and SGOT), organ weight (liver, kidney, spleen, heart, lungs, pancreas and small intestine) and bacteria count (E.coli and Lactobacillus). Result obtained revealed that there was no significant differences (p>0.05) in the haematological, relative organ weight, serum biochemical parameters and E.coli count obtained. However, there was a significant difference (p","PeriodicalId":13887,"journal":{"name":"International journal of Advanced Biological and Biomedical Research","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78949355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

The evaluation and comparison of thermo-physical, chemical and biological properties of palladium (II) complexes on binuclear diamine ligands with different anions using the DFT method 用DFT方法评价和比较不同阴离子双核二胺配体上钯(II)配合物的热物理、化学和生物性质

International journal of Advanced Biological and Biomedical Research Pub Date : 2019-10-01 DOI: 10.33945/SAMI/IJABBR.2019.4.3

Mohammad Jahidul Islam, Md. Nuruzzaman Sarker, A. Kumer, Sunanda Paul

{"title":"The evaluation and comparison of thermo-physical, chemical and biological properties of palladium (II) complexes on binuclear diamine ligands with different anions using the DFT method","authors":"Mohammad Jahidul Islam, Md. Nuruzzaman Sarker, A. Kumer, Sunanda Paul","doi":"10.33945/SAMI/IJABBR.2019.4.3","DOIUrl":"https://doi.org/10.33945/SAMI/IJABBR.2019.4.3","url":null,"abstract":"As cancer is the top killer diseases in the world, the scientists and researchers have been searching the new drugs and remedy methods. Most of the anticancer drugs are organic compounds which were approved by the FDA while metallodrugs are very rare. In the present time, some palladium and rhodium complexes are going to use as anticancer molecules. The palladium (II) complex has higher anticancer activity against different cancer cell that is why the different amine ligands are considered under theoretical study by the method of density functional theory (DFT) to make a new molecule. Some thermo-physical parameter was conducted such as free energy, entropy, dipole moment, binding energy, nuclear energy, electronics energy, the heat of formation. On the other hand, the chemical reactivity properties like occupied Molecular Orbital Highest (HOMO), Lowest Unoccupied Molecular Orbital (LUMO), HOMO-LUMO gap, ionization potential, electronegativity, hardness, softness and electron affinity, and biological properties like charge density, surface area grid, volume, LogP, polarizability, refractivity, molecular mass were calculated using the DFT method. To make comparative biological properties, different anions such as chloride, nitrate, hydroxide, carbonate and sulfate ions were used as homogeneous and heterogeneous adding.","PeriodicalId":13887,"journal":{"name":"International journal of Advanced Biological and Biomedical Research","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80967242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Effect of Feeding Different Levels of Luffa aegyptiaca Extracts on the Growth Performance of Broiler Chicken Fed Corn-Soya Meal Diet 饲喂不同水平埃及丝瓜提取物对玉米-豆粕饲粮肉鸡生长性能的影响

International journal of Advanced Biological and Biomedical Research Pub Date : 2019-10-01 DOI: 10.33945/SAMI/IJABBR.2019.4.1

A. John

引用次数: 1

Evaluation of Spent Engine Oil and other Natural Materials on the Emergence of Harvester Ants (Messor galla Forel) in North Eastern Nigeria 废机油和其他天然物质对尼日利亚东北部收获蚁(Messor galla Forel)出现的影响

International journal of Advanced Biological and Biomedical Research Pub Date : 2019-10-01 DOI: 10.33945/SAMI/IJABBR.2019.4.5

E. Okrikata, C. E. Anaso, S. Bukar

{"title":"Evaluation of Spent Engine Oil and other Natural Materials on the Emergence of Harvester Ants (Messor galla Forel) in North Eastern Nigeria","authors":"E. Okrikata, C. E. Anaso, S. Bukar","doi":"10.33945/SAMI/IJABBR.2019.4.5","DOIUrl":"https://doi.org/10.33945/SAMI/IJABBR.2019.4.5","url":null,"abstract":"Harvester ants (Messor galla Forel) defied various control strategies. Two field experiments were conducted to evaluate the effects of Spent Engine-Oil and other nature-based materials on their emergence in Maiduguri, Borno State of Nigeria. The treatments evaluated are spot application of spent engine-oil and some natural materials in experiment 1 and individual and equal mixture of Pure Neem Seed Kernel oil and Spent Engine-oil in experiment 2. Spot application of permethrin served as control. Experiment 1 results shows no significant difference (p > 0.05) between permethrin and spent engine-oil (which was the most effective treatment). While neem seed oil was significantly (p 0.05) in the population index of ants that emerged from nests treated with aqueous neem seed extract, salt/potash solution and extract of Eugenia aromatic fruit from those of the control. Experiment 2 result showed no significant difference (p 0.05) from the untreated control. While the result shows no significant difference between the treatments, it was observed that equal mixture of Spent Engine-oil and Neem Seed Kernel Oil was most effective, followed by Spent Engine-Oil, Permethrin and Neem Seed Kernel Oil, in that order.","PeriodicalId":13887,"journal":{"name":"International journal of Advanced Biological and Biomedical Research","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87277969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Experimental Investigation of Turbidity Flow in 90 Degree Bend with Mobile Bed 90度弯曲流动床浊度流动的实验研究

International journal of Advanced Biological and Biomedical Research Pub Date : 2019-10-01 DOI: 10.33945/SAMI/IJABBR.2019.4.7

M. Mohammadi, M. Ghomeshi

{"title":"Experimental Investigation of Turbidity Flow in 90 Degree Bend with Mobile Bed","authors":"M. Mohammadi, M. Ghomeshi","doi":"10.33945/SAMI/IJABBR.2019.4.7","DOIUrl":"https://doi.org/10.33945/SAMI/IJABBR.2019.4.7","url":null,"abstract":"Turbidity currents in the ocean and lakes are driven by suspended sediment. The vertical profiles of velocity and excess density are shaped by interaction between the current and bed as well as between the current and the ambient water. This paper presents 48 series of experiments in which saline gravity currents flow through a laboratory sinuous flume. flume contains three successive bends with three different relative curvature radiuses: R/B=2, 4 and 6, 8.5m length, 20cm width and 70cm height. Experiments performed by four discharges (0.7, 1, 1.5, 2 lit/s) and four concentrations (10, 15, 20, 25 gr/lit). ADV was used to record the local velocity. According to the results of experiments on the mobile bed, increasing the concentration of the incoming flow, the flow velocity of the fluid is also increased and, the maximum velocity occurs near the bed instead of the top of the current. The important point in the flow rate profiles is that the rate of increase in velocity depends on changes in the form of the bed due to the increase in concentration. By increasing concentrations of turbidity flow, the shear stress of the bed is also increased. Therefore, the rate of increase in velocity will occur by removing the bed forms and reducing the roughness and shear stress of the bed. Thus, increasing the concentration increases the power of the current, so at the beginning, the roughness and shear stress of the bed increased and then by removal of bed forms shear stress decreased.","PeriodicalId":13887,"journal":{"name":"International journal of Advanced Biological and Biomedical Research","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91352314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Neem Dust Formulations for the Control of Sorghum Stemborers in the Semi-Arid Zone of Nigeria 尼日利亚半干旱区印楝粉防治高粱螟虫效果评价

International journal of Advanced Biological and Biomedical Research Pub Date : 2019-10-01 DOI: 10.33945/SAMI/IJABBR.2019.4.2

E. Okrikata, C. E. Anaso

引用次数: 1

Risk Factors of Gangrenous Cholecystitis in Patients with Acute Cholecystitis: A Cross-Sectional Study 急性胆囊炎患者坏疽性胆囊炎的危险因素:横断面研究

International journal of Advanced Biological and Biomedical Research Pub Date : 2019-09-01 DOI: 10.33945/SAMI/IJABBR.2019.3.7

M. Roozbahani, M. K. Shahmoradi, J. Mehri, Arefe Qolampoor, B. Nasiri, Fatemeh Pakmehr

{"title":"Risk Factors of Gangrenous Cholecystitis in Patients with Acute Cholecystitis: A Cross-Sectional Study","authors":"M. Roozbahani, M. K. Shahmoradi, J. Mehri, Arefe Qolampoor, B. Nasiri, Fatemeh Pakmehr","doi":"10.33945/SAMI/IJABBR.2019.3.7","DOIUrl":"https://doi.org/10.33945/SAMI/IJABBR.2019.3.7","url":null,"abstract":"Introduction: The aim of this study was to determine factors affecting the development of acute cholecystitis toward gangrenous cholecystitis in an Iranian society.Materials and Methods: In this cross-sectional study, all patients who underwent cholecystectomy in the educational hospitals of Khorramabad from August 2013 to August 2016 were included in the study regardless of their age range. The data collected in each patient included demographic data, underlying illnesses, positive history and physical examination prior to surgery, early laboratory findings and preoperative imaging findings. Finally, patients were divided into two groups of acute Cholecystitis and Gangrenous Cholecystitis based on pathological findings after cholecystectomy. The data was finally analyzed using SPSS software.Results: 51 patients were examined during the study. Histological studies indicated the presence of microscopic evidence of acute cholecystitis in all patients, of which 19 had histological evidence of Gangrenous Cholecystitis. In this study, nine variables that could be effective on the prognosis of acute cholecystitis and its progression toward the Gangrenous Cholecystitis were identified. These variables included age, WBC count, diabetes mellitus and coronary artery disease, fluid accumulation around gallbladder, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, and lipase. Finally, multivariate analysis was performed using logistic regression. It was found that the age of ≥51 was effective in the development of diabetes mellitus.Conclusion: In this study, it was observed that high age, diabetes mellitus and leukocytosis could lead to the development of acute cholecystitis toward Gangrenous Cholecystitis, a finding that requires more extensive studies with more sample size.","PeriodicalId":13887,"journal":{"name":"International journal of Advanced Biological and Biomedical Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85312101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Factors Affecting the Use of Sustainable Agriculture in Iran's Potato Cultivars 影响伊朗马铃薯品种可持续农业利用的因素

International journal of Advanced Biological and Biomedical Research Pub Date : 2019-07-01 DOI: 10.33945/SAMI/IJABBR.2019.3.3

Tahmineh Kashani, M. O. Najafabadi, F. Lashgarara

{"title":"Factors Affecting the Use of Sustainable Agriculture in Iran's Potato Cultivars","authors":"Tahmineh Kashani, M. O. Najafabadi, F. Lashgarara","doi":"10.33945/SAMI/IJABBR.2019.3.3","DOIUrl":"https://doi.org/10.33945/SAMI/IJABBR.2019.3.3","url":null,"abstract":"Current research examines the economic, social, cultural, policy, educational and promotional factors in using sustainable agriculture operations. Research is an applied type and its method is correlation. The statistical population consisted of 102 members of Iran Potato Cultivars. Data were collected using a census method and a questionnaire was used. The Cronbach's alpha coefficient was obtained among 0.4723.0 ± 0.946 / 0, indicating the reliability of this tool. Statistical analysis of data was performed using SPSS20 software. The results of regression analysis indicated that three variables: economic factors, policy factors, educational and promotional factors were the most important independent variables affecting the dependent variable of sustainable agriculture, that was 42.1% of the variation of dependent variable (implementation of sustainable agricultural activity) that explain the research.Also the results indicated that the economic factor variable with the beta coefficient equal to 0.339 is the most important variable affecting the implementation of sustainable agricultural practices. The variable policy making factor with a regression coefficient of 0.146 is the least important factor affecting the implementation of sustainable agricultural operations","PeriodicalId":13887,"journal":{"name":"International journal of Advanced Biological and Biomedical Research","volume":"80 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84332666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0