New Frontiers in Medicine and Medical Research Vol. 8最新文献

{"title":"Management of Large Periapical Lesion of Endodontic Origin with the Combination of Second Generation Platelet Extract and Xenograft","authors":"Pradnya Sunilkumar Nagmode, B. S. Kapse, Harshal V Basatwar, Shubham P. Godge, Prachi Janbandhu","doi":"10.9734/bpi/nfmmr/v8/3733f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v8/3733f","url":null,"abstract":"Periapical inflammatory lesion is the local response of bone around the apex of tooth that develops after the necrosis of the pulp tissue or substantial periodontal disease. Periapical surgery aims to remove periapical pathology to achieve wound healing and regeneration of bone and periodontal tissue. The purpose of this case report is to through a light on use of platelet rich fibrin and bone graft in the treatment of large periapical lesion. Platelet rich fibrin (PRF) is a magnificent tissue engineering product and has gained substantial popularity due to its promising results in wound healing bone induction. Bone graft used in both cases in the present case report was xenograft which is similar to human cancellous bone and is known to have osteoinductive as well as osteoconductive properties.\u0000Objectives:\u0000\u0000To remove infected, inflamed, necrotic and granulation tissues.\u0000To disinfect and decontaminate the peri-apical field.\u0000To achieve superior and rapidly progressive healing in peri- apical region by regenerative surgical approach using second generation Platelet extract and Xenograft.","PeriodicalId":138368,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 8","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129151416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case Reports on Surgical Lengthening of the Clinical Crown","authors":"A. Dixit, Seema K. Dixit","doi":"10.9734/bpi/nfmmr/v8/3561f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v8/3561f","url":null,"abstract":"","PeriodicalId":138368,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 8","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124669734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on Color Words Pick-Out Test (CWPT) Available for Classifying the Slight Disorder on the Preclinical Stage of Dementia","authors":"T. Shimura, E. Okuyama, H. Osugi","doi":"10.9734/bpi/nfmmr/v8/12198d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v8/12198d","url":null,"abstract":"Objective: Before concept of mild cognitive impairment (MCI) and preclinical stage of dementia (PCSD) our study started to detect slight declines in the brain. The purpose of this study is to clarify the basis of the ability of the devised CWPT (Color Word Pick-out Test) to detect slight disorder and classify it at the MCI and PCSD. \u0000Methods: CWPT is an application of Stroop effect and is including an examination of episodic memory to obtain the evidence and ? activation of the prefrontal lobe using an inferred spectroscopy, ? criterion-related validity using CWPT, WCST, HCL, FAB and MMSE ? sensitivity and specificity using MMSE and CWPT are examined. \u0000Results: ? It is found using a near infrared spectroscopy that CWPT is the most effective test for the brain activation, in comparison with quick repetition of 4-5numbers in order, in reverse order, Kawashima arithmetic drill and KPT (Kana Pick-out Test). ? among the histograms obtained from 22 healthy aging people, only CWPT and WCST show normal distributions besides CWPT has good correlation with WCST. ? Sensitivity and specificity are calculated using MMSE as a true condition and CWPT as a predicted condition for 29 subjects with dementia. Sensitivity becomes 0.963 and specificity becomes 1.0 by the cutoff of the average-1.5SD of CWPT. \u0000Conclusion: As a result of these analyses, it has been suggested that CWPT can be used to classify the level of disorder during MCI and the preclinical stage of dementia.","PeriodicalId":138368,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 8","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129226155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on Muscle Pedicle Graft in Avascular Necrosis Femoral Head","authors":"R. Bhargava","doi":"10.9734/bpi/nfmmr/v8/12212d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v8/12212d","url":null,"abstract":"Aims: To assess the effectiveness of muscle pedicle graft in avascular necrosis (AVN) head femur in Grade 1 and Grade 2 AVN of femoral head and grade 1 and grade 2 as head sparing procedure. \u0000Method: The pixel count in Tc-99 bone scan single photon emission computed tomography (SPECT) was used as perfusion analysis through a standardized procedure of assessment at six monthly intervals. Comparisons of the scan and the counts at each interval was used to determine whether the procedure was producing a beneficial effect and to what extent. The cases were followed-up for a minimum period of two years. \u0000Result: It was discovered that the comparative ratios had a bearing on the clinical improvement and could be used as a predictor variable for the outcome. They also had a significant prognostic value. \u0000Conclusions: Muscle pedicle graft in Grade 1 and Grade 2 AVN femoral head does benefit the patient. The SPECT analysis of the Tc-99 bone scan can be used as a monitor and reasonably predict the outcome and adverse end results.","PeriodicalId":138368,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 8","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115023760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationships between Myocardial Damage Biomarkers with Infarct Size and Ejection Fraction Impairment Assessed by Cardiac Magnetic Resonance","authors":"Lucía Del Valle-Batalla, Raúl Castillo-Astorga, Rodolfo Prieto-Riveros, Jaime Gonzalez, R. Aguayo, Kjersti Nes, C. Ramos, J. Prieto, R. Rodrigo","doi":"10.9734/bpi/nfmmr/v8/3917f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v8/3917f","url":null,"abstract":"Background: Acute myocardial infarction (AMI) is the leading cause of morbidity and mortality worldwide. The final infarct size (FIS) and left ventricular ejection fraction (LVEF) are the greatest predictors of post-AMI mortality, with cardiac magnetic resonance (CMR) being the gold standard method for their measurement. Myocardial damage biomarkers, such as creatine kinase (CK) and myocardial creatine kinase (CKMB) are currently used to diagnose AMI and estimate the myocardial damage extent. It would be plausible to use them as predictors of FIS and LVEF; however, current evidence is not available up to date. \u0000Objective: To determine the potential power of plasma CK and CKMB levels as predictors of FIS and LVEF impairment, respectively, on the basis of their correlation in patients undergoing primary coronary angioplasty (PCA) following ST-elevation acute myocardial infarction (STEMI). \u0000Methodology: A retrospective analysis of PREVEC Trial (ISRCTN registry: 56034553), a multicentric, randomized, double-blind clinical study was performed. Sixty-seven patients with STEMI scheduled for PCA were enrolled. The CMR was performed 7-15 days after the event. Three radiologists blinded to clinical information measured FIS and LVEF. Total CK and CKMB were measured in peripheral venous blood at 6-8 hours after PCA. Correlation coefficient were obtained, and the tests were considered significant with a p value <0.05. The software GraphPrism 6.0 was used for the statistical analysis. \u0000Results: A significant positive correlation was obtained between levels of cardiac biomarkers and FIS [total CK (r-square 0.3, p<0.0001) and CK MB (r-square 0.15, p<0.0027)]. In addition, the levels of these biomarkers showed a significant negative correlation with LVEF [total CK (r-square 0.3, p<0.0001) and CK MB (r-square 0.18, p<0.0012)]. \u0000Conclusion: These results are consistent with the view that the myocardial damage biomarkers CK and CKMB are reliable as predictors of FIS and LVEF measured by CMR in post-AMI patients. These data suggest that these biomarkers could be included in future Risk Scores.","PeriodicalId":138368,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 8","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116733626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Clinical Significance of Inflammatory Biomarkers of Atherosclerosis in Carotid Disease","authors":"O. Dubenko","doi":"10.9734/bpi/nfmmr/v8/12172d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v8/12172d","url":null,"abstract":"Atherosclerotic disease of the carotid arteries is a major cause of ischemic stroke. The degree of carotid stenosis is the main marker for assessing the risk of stroke in \"carotid disease\", however, the degree of stenosis alone cannot accurately predict future stroke. Asymptomatic carotid artery stenosis is a well-recognized risk factor for ischemic stroke. Non-stenotic atherosclerotic carotid artery plaques can also cause atheroembolism in the presence of ulceration and rupture of the plaque. We aimed to summarizes the current available evidence on the association between carotid atherosclerosis and serum inflammatory biomarkers. Atherosclerosis is a dynamic process involving inflammatory and thrombotic mechanisms with progressive degree of stenosis. The ability to predict the progression of atherosclerotic stenosis can be useful for clinical practice in assessing the risk of stroke development and its prevention. To identify subgroup of patients with higher risk for ipsilateral stroke is important aim. Inflammatory activity is an integral indicator of the development of atherosclerosis and its complications and plays a key role in the pathogenesis, progression, rupture of atherosclerotic plaque and the development of clinical manifestations in patients with atherosclerotic carotid stenosis. Several serum inflammatory markers such as C-reactive protein, interleukin-6, pentraxin 3, lipoprotein-associated phospholipase A2, adhesion molecules ICAM-1 and selectins and matrix metalloproteinases proposed as tool for risk assessment in patients with carotid atherosclerosis. Even though there are some cardiovascular biomarkers identified, they have only modest predictive value. Some well-established biomarkers for coronary disease are not relevant to carotid atherosclerosis. Future research may clarify the clinical significance of serum inflammatory biomarker in carotid atherosclerosis.","PeriodicalId":138368,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 8","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128586240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study Perception of First-Year Medical Students on the Use of WhatsApp as a Supplementary Learning Tool","authors":"K. Ramachandran","doi":"10.9734/bpi/nfmmr/v8/11608d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v8/11608d","url":null,"abstract":"","PeriodicalId":138368,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 8","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121231045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Duties of Doctor in Case of Suspected Poisoning","authors":"H. K. Sahoo, K. Mishra, B. Panda","doi":"10.9734/bpi/nfmmr/v8/3524f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v8/3524f","url":null,"abstract":"Duties of registered medical practitioner (RMP) while dealing a suspected poisoning case increases as it is a medical emergency along with the legal issues associated with it. The role of doctor is not only to follow a basic management protocol, but also to handle the legal formalities, following the treatment part. The basic treatment modalities should be supportive care, accurate diagnosis, use of toxidromes, removal of unabsorbed poison, elimination of absorbed poison and antidote administration if available. The legal documentation, following treatment should be clear and accurate. Police information should be given where necessary. The doctor is duty bound to all other legal and ethical work, concerning a poisoning case otherwise liable for punishment as per the current law. So by applying our skill and knowledge and doing our duty correctly, we doctors not only save the life of the patients but also protect the legal rights of individual or the state.","PeriodicalId":138368,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 8","volume":"117 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116109577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}