New Frontiers in Medicine and Medical Research Vol. 8最新文献

{"title":"Early Repolarisation Syndrome in SCD Survivor Patients","authors":"R. Srivastava, Bhanu Mahajan, S. Dutta","doi":"10.9734/bpi/nfmmr/v8/12179d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v8/12179d","url":null,"abstract":"Early repolarization seen in ECGS can be benign and malignant. Fatal ventricular arrythmia may occur with malignant form. Correlating malignant ECG findings with proper past and present history of patient can prevent these events in future.","PeriodicalId":138368,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 8","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127028645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Vitamin D3 in Incidence of Metabolic Syndrome","authors":"Arkajit Dasgupta, S. Maiti, Debojyoti Bhattacharjee","doi":"10.9734/bpi/nfmmr/v8/12120d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v8/12120d","url":null,"abstract":"Metabolic Syndrome is defined as presence of central obesity with certain other metabolic dysregulation like increased fasting blood glucose, dyslipidemia and hypertension. The criteria of metabolic syndrome are increasing day by day. All the conventional and expanded criteria are cardiovascular risk factors. Decreased level of vitamin D3 due sedentary life style is also a potent cardiovascular risk factor. In this study, we have tried to knot metabolic syndrome with vitamin D3.","PeriodicalId":138368,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 8","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129969018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Report on Vascular Malformation of Kidney","authors":"Debajani Deka, Amrita Nidhi, N. Yadav","doi":"10.9734/bpi/nfmmr/v8/3562f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v8/3562f","url":null,"abstract":"The kidneys are a pair of retroperitoneal organs located at the level of the L1, L2, and L3 positions. At the level of the tenth rib, the superior portion of the kidney is located within the lower thoracic cage. Due to the existence of the liver, the right kidney is lower than the left kidney. The adult kidney weights about 150 gm. Right kidney is broad and short and left kidney is narrow and long. Right renal artery is longer than the left renal artery and right renal vein is shorter than the left renal vein. Renal arteries are end arteries while veins anastomose freely. Left gonadal vein and left suprarenal vein (adrenal vein) drain into the left renal vein. Right suprarenal vein and gonadal vein drain into inferior vena cava. Both the ureters are draining from the kidneys behind the renal artery. From anterior to posterior we get renal vein, renal artery and ureter. \u0000In this case report we found pair of kidney with renal vein and renal artery. Right renal artery is longer than the left renal artery and left renal vein is longer than the right renal vein. We can see the posterior aspect of inferior vena cava.Left gonadal vein and left suprarenal vein (adrenal vein) are draining into the left renal vein. Right suprarenal vein and gonadal vein are draining into inferior vena cava. Both the ureters are draining from lower end behind the renal artery. From anterior to posterior we get renal artery, renal vein and ureter. Here we are getting duplication of ureter in the left side. On right side, there three accessory renal arteries, one to the inferior pole and two to the hilum behind the main renal artery of the kidney. On the left side, there are two renal arteries one going to the hilum behind the main renal artery and one going to the inferior pole of the kidney. On right side ureter is draining behind the renal vein. The duplex ureter drains behind the renal vein on the left side. The left suprarenal vein is twisted here, and the gland is also visible farther down because the venacava is turned down, revealing its posterior aspect, and no venous tributaries flow from it.","PeriodicalId":138368,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 8","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130131979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determining the Impact of CAT Score in Chronic Obstructive Pulmonary Diseases Patients Health in Our Region","authors":"S. Choudhary","doi":"10.9734/bpi/nfmmr/v8/11706d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v8/11706d","url":null,"abstract":"COPD is a disease state that causes lot of human suffering, is now recognized as a common disease in developing countries and is one of the fastest growing chronic cause of death. Pulmonary function tests are essential for the diagnosis and evaluation of the severity of COPD but other measures of functional status such as dyspnoea, exercise performance and health status are important components of COPD that cannot be measured by this method. The COPD assessment test (CAT) is a new eight-item specific questionnaire and is intended to provide a short, simple and self-administered test for evaluating symptoms, in assessing the impact of COPD on health status (Quality Of Life) .This study shows the usefulness of CAT score in our region. The clinical characteristics, Gold Severity and FEVI 1 % of present study were compared with earlier studies of different countries. Total 70 patients with COPD were studied between May 2014 to September 2014.Detail clinical history was obtained .Assessment of symptom severity was made based on the CAT questioanaire.They were subjected to Pulmonary function test (pre and post bronchodilator therapy) and oxygen saturation measurement. Majority of the patients were Male 42 (60%).Total 41(58.6%) patients were smokers of which 36 (87.80%) were males.18(25.7%) patients had positive history of Chula exposure of which 17(94.44%) were females Mean Age of patients was 60.34 SD 9.9, Mean FEV1 62.33 SD 18.2, and SPO2 94.26 SD 2.27. Patients were classified into two groups. Group 1 of low symptoms having CAT Score 10.More than half of the patients 80% had a high CAT score of >10 of Group 2.Most of the patients were of moderate obstruction 50%. Patients in whom Forced expiratory volume in 1 s percent (FEV1%) predicted was significantly decreased had a significantly increased the CAT score (t = 2.67 p= .009). Patients with severe stage of the disease (as GOLD criteria) had high CAT score i.e. have a positive corelation whereas CAT score and FEVI % had inverse co relation. The mean FEV1% predicted was similar to France where as high compared to Germany ,Netherlands ,Spain and U.S.A. and lower than Belgium. The CAT questionnaire proves to be a sensitive test in detecting COPD health status as a simple and reliable tool. By the help of CAT questionnaire the patients and clinician’s awareness of COPD would be improved to make an early diagnosis thus providing a useful and objective tool for early recognition and long term clinical and therapeutic monitoring of COPD patients especially in the clinical settings where spirometry is not yet available. \u0000Aims and Objectives:   \u0000 \u0000COPD Assessment TEST (CAT), in assessing the impact on COPD health status (Quality Of Life) in our region. \u0000Usefulness of CAT scoring in monitoring health status. \u0000Comparison of clinical characteristics of present study with earlier studies of different countries","PeriodicalId":138368,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 8","volume":"150 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128115979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous Pneumomediastinum and Subcutaneous Emphysema: Unusual Presentation of H1N1 Influenza in Adult","authors":"Naorem Dhaneshwor Singh, J. Kaur, D. Deepak, Lobzang Dawa","doi":"10.9734/bpi/nfmmr/v8/3677f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v8/3677f","url":null,"abstract":"Swine flu is highly contagious acute respiratory disease caused by a subtype of influenza A virus. After the 2009 H1N1 virus pandemia the strain has caused multiple localized outbreaks in various part of the world. It typically presents with fever, cough, sore throat, fatigue, headache, dyspnea, myalgia, vomiting, and diarrhea but rarely severe complications like rapidly progressive pneumonia, septic shock and multi-organ failure may appear. \u0000H1N1 swine influenza complicating with spontaneous pneumomediastinum is uncommon, occurring mostly in children with a predisposing co-morbidity like asthma. Though rare, its occurrence in adult should be considered a possibility. Pneumomediastinum is potentially life threatening if not diagnosed and managed promptly. \u0000Here we report in detail a case of adult H1N1 swine influenza developing spontaneous pneumomediastinum (SPM) in absence of any known predisposing comorbidity.","PeriodicalId":138368,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 8","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125688118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Varicocele: Anatomical Background and Uroradiological Aspects","authors":"K. Ramachandran, S. Krishnamoorthy","doi":"10.9734/bpi/nfmmr/v8/11917d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v8/11917d","url":null,"abstract":"Introduction: Varicocele is the dilatation of the pampiniform plexuses. It is a treatable cause of infertility. The incidence is higher in infertile men, ranging from 35-80%. Although various mechanisms are postulated for the formation of varicocele, the pathological mechanisms by which varicocele causes sperm dysfunction are oxidative stress, testicular hypoperfusion, and heat stress. \u0000Anatomical aspects: The intricacy of the venous drainage of the scrotum and its contents and the criss-crossing of the veins makes the thermo-regulatory mechanism regulating spermatogenesis, even more complex. The Cremaster and Dartos greatly aid in facilitating the thermo-regulatory mechanism of scrotal wall, which forms the anatomical basis of oligospermia in patients with varicocele. \u0000Urological aspects: Apart from a visible change in seminal parameters, the benefits of varicocelectomy have extended on to an improvement in serum testosterone and enhancement of erectile and ejaculatory functions. With a greater knowledge of the pathophysiology of varicocele and with better understanding of the roles of gene polymorphisms and reactive oxygen species, the indications for varicocelectomy gain more support and evidence. \u0000Conclusions: A sound anatomical knowledge and an indepth understanding of the events that take place at molecular level might shift the treatment focus in future from varicocelectomy to molecular targeted therapies.","PeriodicalId":138368,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 8","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134630803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review of Sympathetic Ophthalmia as a Major Sight-threatening Disorder","authors":"Mohammed Alkhaibari","doi":"10.9734/bpi/nfmmr/v8/3834f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v8/3834f","url":null,"abstract":"","PeriodicalId":138368,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 8","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129869712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimation of Placental Thickness with Gestational age in Second &Third Trimester-An Ultrasonographic Study","authors":"A. Sinha, P. Potdar","doi":"10.9734/bpi/nfmmr/v8/3288f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v8/3288f","url":null,"abstract":"","PeriodicalId":138368,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 8","volume":"305 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113966945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Diagnostic Difficulty on ANA Negative/ Seronegative Systemic Lupus Erythematosus with Diffuse Alveolar Haemorrhage","authors":"P. Upadhya, A. Priya, M. Chari, P. Toi, G. Vishnukanth","doi":"10.9734/bpi/nfmmr/v8/3807f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v8/3807f","url":null,"abstract":"A 45-year-old hypertensive woman had a dry cough, dyspnea, and a crusted nonhealing ulcer on her right ankle for one month. She was suffering from worsening anaemia, proteinuria, and thrombocytopenia. A CT pulmonary angiogram revealed pulmonary hypertension, a thrombus in the left internal jugular vein, and bilateral multilobar opacities. A Doppler USG revealed thrombus in the right popliteal and left jugular veins. Serology revealed a low C3, C4, negative ANA with antiphospholipid antibodies that were twice positive. Diffuse alveolar bleeding was confirmed by bronchoalveolar lavage (DAH). An ulcer biopsy revealed lymphocytic vasculitis, which is a sign of immune complex deposition disorder.ANA negative SLE with DAH was identified after meeting the clinical and immunological criteria of the Systemic Lupus International Collaborating Clinics (SLICC).","PeriodicalId":138368,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 8","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130194909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Applications of Machine Learning in Stroke Care","authors":"Jing Zhang","doi":"10.9734/bpi/nfmmr/v8/3919f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v8/3919f","url":null,"abstract":"Stroke is one of the leading causes of death and disability worldwide. In recent years, machine learning (ML) methods have been increasingly applied to stroke care. This  research work  reviewed studies using ML approach in stroke care to provide an overview of this field. The advances of ML techniques have made it possible to automatically examine carotid plaques (for stroke risk stratification), detect stroke lesions on imaging, identify possible treatment complications in patients, facilitate brain-computer-interface (BCI)-aided rehabilitation, and predict stroke prognosis. The performances of certain machine learning applications are non-inferior to clinicians in areas such as measuring carotid intima-media thickness and detecting early damage of ischemic stroke on CT imaging. In addition, ML applications in clinical outcome prediction have similar or better performances than the conventional method logistic regression. However, there are still challenges in areas such as automated lesion segmentation, BCI-aided rehabilitation and long-term stroke prognosis prediction. Newly developed ML methods such as deep learning may be promising to overcome the challenges. Further research is needed to verify and optimize these ML applications, and large-sample studies and proper validation are warranted to make these ML methods more accurate, generalizable and reliable. As the need for precision medicine in stroke grows and as the technology of machine learning advances, it is anticipated that the potential of machine learning applications will be released to improve computer-aided stroke prevention and transform conventional stroke medicine into data-driven personalized stroke management, which will reduce morbidity and mortality rates, enhance stroke care and set patients free from stroke-caused disability.","PeriodicalId":138368,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 8","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130915224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}